Ring finger protein 213 assembles into a sensor for ISGylated proteins with antimicrobial activity von Thery, Fabien, Martina, Lia, Asselman, Caroline, Zhang, Yifeng, Vessely, Madeleine, Repo, Heidi, Sedeyn, Koen, Moschonas, George D., Bredow, Clara, Teo, Qi Wen, Zhang, Jingshu, Leandro, Kevin, Eggermont, Denzel, De Sutter, Delphine, Boucher, Katie, Hochepied, Tino, Festjens, Nele, Callewaert, Nico, Saelens, Xavier, Dermaut, Bart, Knobeloch, Klaus-Peter, Beling, Antje, Sanyal, Sumana, Radoshevich, Lilliana, Eyckerman, Sven, Impens, Francis

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Two distinct ubiquitin-binding motifs in A20 mediate its anti-inflammatory and cell-protective activities von Martens, Arne, Priem, Dario, Hoste, Esther, Vetters, Jessica, Rennen, Sofie, Catrysse, Leen, Voet, Sofie, Deelen, Laura, Sze, Mozes, Vikkula, Hanna, Slowicka, Karolina, Hochepied, Tino, Iliaki, Kalliopi, Wullaert, Andy, Janssens, Sophie, Lamkanfi, Mohamed, Beyaert, Rudi, Armaka, Marietta, Bertrand, Mathieu J. M., van Loo, Geert

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OTULIN maintains skin homeostasis by controlling keratinocyte death and stem cell identity von Hoste, Esther, Lecomte, Kim, Annusver, Karl, Vandamme, Niels, Roels, Jana, Maschalidi, Sophia, Verboom, Lien, Vikkula, Hanna-Kaisa, Sze, Mozes, Van Hove, Lisette, Verstaen, Kevin, Martens, Arne, Hochepied, Tino, Saeys, Yvan, Ravichandran, Kodi, Kasper, Maria, van Loo, Geert

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NLRP2 controls age-associated maternal fertility von Kuchmiy, Anna A, D'Hont, Jinke, Hochepied, Tino, Lamkanfi, Mohamed

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Familial Mediterranean fever mutations lift the obligatory requirement for microtubules in Pyrin inflammasome activation von Van Gorp, Hanne, Saavedra, Pedro H. V., de Vasconcelos, Nathalia M., Van Opdenbosch, Nina, Vande Walle, Lieselotte, Matusiak, Magdalena, Prencipe, Giusi, Insalaco, Antonella, Van Hauwermeiren, Filip, Demon, Dieter, Bogaert, Delfien J., Dullaers, Melissa, De Baere, Elfride, Hochepied, Tino, Dehoorne, Joke, Vermaelen, Karim Y., Haerynck, Filomeen, De Benedetti, Fabrizio, Lamkanfi, Mohamed

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A knock-in/knock-out mouse model of HSPB8-associated distal hereditary motor neuropathy and myopathy reveals toxic gain-of-function of mutant Hspb8 von Bouhy, Delphine, Juneja, Manisha, Katona, Istvan, Holmgren, Anne, Asselbergh, Bob, De Winter, Vicky, Hochepied, Tino, Goossens, Steven, Haigh, Jody J., Libert, Claude, Ceuterick-de Groote, Chantal, Irobi, Joy, Weis, Joachim, Timmerman, Vincent

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Caspase-1 Engagement and TLR-Induced c-FLIP Expression Suppress ASC/Caspase-8-Dependent Apoptosis by Inflammasome Sensors NLRP1b and NLRC4 von Van Opdenbosch, Nina, Van Gorp, Hanne, Verdonckt, Maarten, Saavedra, Pedro H.V., de Vasconcelos, Nathalia M., Gonçalves, Amanda, Vande Walle, Lieselotte, Demon, Dieter, Matusiak, Magdalena, Van Hauwermeiren, Filip, D’Hont, Jinke, Hochepied, Tino, Krautwald, Stefan, Kanneganti, Thirumala-Devi, Lamkanfi, Mohamed

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MeCP2 binds to methylated DNA independently of phase separation and heterochromatin organisation von Pantier, Raphaël, Brown, Megan, Han, Sicheng, Paton, Katie, Meek, Stephen, Montavon, Thomas, Shukeir, Nicholas, McHugh, Toni, Kelly, David A., Hochepied, Tino, Libert, Claude, Jenuwein, Thomas, Burdon, Tom, Bird, Adrian

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MALT1 Proteolytic Activity Suppresses Autoimmunity in a T Cell Intrinsic Manner von Demeyer, Annelies, Skordos, Ioannis, Driege, Yasmine, Kreike, Marja, Hochepied, Tino, Baens, Mathijs, Staal, Jens, Beyaert, Rudi

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OTULIN protects the intestinal epithelium from apoptosis during inflammation and infection von Verboom, Lien, Anderson, Christopher J., Jans, Maude, Petta, Ioanna, Blancke, Gillian, Martens, Arne, Sze, Mozes, Hochepied, Tino, Ravichandran, Kodi S., Vereecke, Lars, van Loo, Geert

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Innovative mouse models for the tumor suppressor activity of Protocadherin-10 isoforms von Kleinberger, Irene, Sanders, Ellen, Staes, Katrien, Van Troys, Marleen, Hirano, Shinji, Hochepied, Tino, Lemeire, Kelly, Martens, Liesbet, Ampe, Christophe, van Roy, Frans

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Sterile triggers drive joint inflammation in TNF‐ and IL ‐1β‐dependent mouse arthritis models von Thiran, Alexandra, Petta, Ioanna, Blancke, Gillian, Thorp, Marie, Planckaert, Guillaume, Jans, Maude, Andries, Vanessa, Barbry, Korneel, Gilis, Elisabeth, Coudenys, Julie, Hochepied, Tino, Vanhove, Christian, Gracey, Eric, Dumas, Emilie, Manuelo, Teddy, Josipovic, Ivan, van Loo, Geert, Elewaut, Dirk, Vereecke, Lars

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Protein citrullination and NET formation do not contribute to the pathology of A20/TNFAIP3 mutant mice von Van Damme, Karel F. A., Hertens, Pieter, Martens, Arne, Gilis, Elisabeth, Priem, Dario, Bruggeman, Inge, Fossoul, Amelie, Declercq, Jozefien, Aegerter, Helena, Wullaert, Andy, Hochepied, Tino, Hoste, Esther, Vande Walle, Lieselotte, Lamkanfi, Mohamed, Savvides, Savvas N., Elewaut, Dirk, Lambrecht, Bart N., van Loo, Geert

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The impact of hepatocyte-specific deletion of hypoxia-inducible factors on the development of polymicrobial sepsis with focus on GR and PPARα function von Vanderhaeghen, Tineke, Timmermans, Steven, Eggermont, Melanie, Watts, Deepika, Vandewalle, Jolien, Wallaeys, Charlotte, Nuyttens, Louise, De Temmerman, Joyca, Hochepied, Tino, Dewaele, Sylviane, Berghe, Joke Vanden, Sanders, Niek, Wielockx, Ben, Beyaert, Rudi, Libert, Claude

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Caspase-14 protects against epidermal UVB photodamage and water loss von Borgonie, Gaetan, Vandenabeele, Peter, Hachem, Jean-Pierre, Gilbert, Barbara, Presland, Richard B, Van Damme, Petra, Declercq, Wim, Libert, Claude, Gevaert, Kris, Hoste, Esther, D'Herde, Katharina, Hochepied, Tino, Van den Broecke, Caroline, Vandekerckhove, Joël, Ovaere, Petra, Lippens, Saskia, Schoonjans, Luc, Denecker, Geertrui

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Zinc inhibits lethal inflammatory shock by preventing microbe‐induced interferon signature in intestinal epithelium von Souffriau, Jolien, Timmermans, Steven, Vanderhaeghen, Tineke, Wallaeys, Charlotte, Van Looveren, Kelly, Aelbrecht, Lindsy, Dewaele, Sylviane, Vandewalle, Jolien, Goossens, Evy, Verbanck, Serge, Boyen, Filip, Eggermont, Melanie, De Commer, Lindsey, De Rycke, Riet, De Bruyne, Michiel, Tito, Raul, Ballegeer, Marlies, Vandevyver, Sofie, Velho, Tiago, Moita, Luis Ferreira, Hochepied, Tino, De Bosscher, Karolien, Raes, Jeroen, Van Immerseel, Filip, Beyaert, Rudi, Libert, Claude

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A new mouse model to study the role of ectopic Nanos3 expression in cancer von Andries, Vanessa, De Keuckelaere, Evi, Staes, Katrien, Hochepied, Tino, Taminau, Joachim, Lemeire, Kelly, Birembaut, Philippe, Berx, Geert, van Roy, Frans

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Challenging the conventional wisdom: Re‐evaluating Smpd3's role in extracellular vesicle biogenesis von Burgelman, Marlies, Dujardin, Pieter, Willems, Anthony, Hochepied, Tino, Van Imschoot, Griet, Van Wonterghem, Elien, Van Hoecke, Lien, Vandendriessche, Charysse, Vandenbroucke, Roosmarijn E.

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p120 Catenin-Mediated Stabilization of E-Cadherin Is Essential for Primitive Endoderm Specification von Pieters, Tim, Goossens, Steven, Haenebalcke, Lieven, Andries, Vanessa, Stryjewska, Agata, De Rycke, Riet, Lemeire, Kelly, Hochepied, Tino, Huylebroeck, Danny, Berx, Geert, Stemmler, Marc P, Wirth, Dagmar, Haigh, Jody J, van Hengel, Jolanda, van Roy, Frans

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Mice overexpressing β-1,4-Galactosyltransferase I are resistant to TNF-induced inflammation and DSS-induced colitis von Vanhooren, Valerie, Vandenbroucke, Roosmarijn E, Dewaele, Sylviane, Van Hamme, Evelien, Haigh, Jody J, Hochepied, Tino, Libert, Claude

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