Human Fatty Liver Disease: Old Questions and New Insights von Cohen, Jonathan C., Horton, Jay D., Hobbs, Helen H.

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Accumulation of PNPLA3 on lipid droplets is the basis of associated hepatic steatosis von BasuRay, Soumik, Wang, Yang, Smagris, Eriks, Cohen, Jonathan C., Hobbs, Helen H.

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PNPLA3, CGI‐58, and Inhibition of Hepatic Triglyceride Hydrolysis in Mice von Wang, Yang, Kory, Nora, BasuRay, Soumik, Cohen, Jonathan C, Hobbs, Helen H

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Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease von Cohen, Jonathan C, Hobbs, Helen H, Romeo, Stefano, Kozlitina, Julia, Xing, Chao, Pertsemlidis, Alexander, Cox, David, Pennacchio, Len A, Boerwinkle, Eric

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Adiposity amplifies the genetic risk of fatty liver disease conferred by multiple loci von Stender, Stefan, Kozlitina, Julia, Nordestgaard, Børge G, Tybjærg-Hansen, Anne, Hobbs, Helen H, Cohen, Jonathan C

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Molecular biology of PCSK9: its role in LDL metabolism von Horton, Jay D., Cohen, Jonathan C., Hobbs, Helen H.

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PCSK9: a convertase that coordinates LDL catabolism von Horton, Jay D., Cohen, Jonathan C., Hobbs, Helen H.

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Inactivation of ANGPTL3 reduces hepatic VLDL-triglyceride secretion von Wang, Yan, Gusarova, Viktoria, Banfi, Serena, Gromada, Jesper, Cohen, Jonathan C, Hobbs, Helen H

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Pnpla3I148M knockin mice accumulate PNPLA3 on lipid droplets and develop hepatic steatosis von Smagris, Eriks, BasuRay, Soumik, Li, John, Huang, Yongcheng, Lai, Ka‐man V., Gromada, Jesper, Cohen, Jonathan C., Hobbs, Helen H.

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Rare loss-of-function mutations in ANGPTL family members contribute to plasma triglyceride levels in humans von Romeo, Stefano, Yin, Wu, Kozlitina, Julia, Pennacchio, Len A, Boerwinkle, Eric, Hobbs, Helen H, Cohen, Jonathan C

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Atypical angiopoietin-like protein that regulates ANGPTL3 von Quagliarini, Fabiana, Wang, Yan, Kozlitina, Julia, Grishin, Nick V, Hyde, Rhonda, Boerwinkle, Eric, Valenzuela, David M, Murphy, Andrew J, Cohen, Jonathan C, Hobbs, Helen H

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Mice lacking ANGPTL8 (Betatrophin) manifest disrupted triglyceride metabolism without impaired glucose homeostasis von Wang, Yan, Quagliarini, Fabiana, Gusarova, Viktoria, Gromada, Jesper, Valenzuela, David M., Cohen, Jonathan C., Hobbs, Helen H.

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A Spectrum of PCSK9 Alleles Contributes to Plasma Levels of Low-Density Lipoprotein Cholesterol von Kotowski, Ingrid K., Pertsemlidis, Alexander, Luke, Amy, Cooper, Richard S., Vega, Gloria L., Cohen, Jonathan C., Hobbs, Helen H.

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Crystal structure of the human sterol transporter ABCG5/ABCG8 von Lee, Jyh-Yeuan, Kinch, Lisa N., Borek, Dominika M., Wang, Jin, Wang, Junmei, Urbatsch, Ina L., Xie, Xiao-Song, Grishin, Nikolai V., Cohen, Jonathan C., Otwinowski, Zbyszek, Hobbs, Helen H., Rosenbaum, Daniel M.

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Molecular Characterization of Loss-of-Function Mutations in PCSK9 and Identification of a Compound Heterozygote von Zhao, Zhenze, Tuakli-Wosornu, Yetsa, Lagace, Thomas A., Kinch, Lisa, Grishin, Nicholas V., Horton, Jay D., Cohen, Jonathan C., Hobbs, Helen H.

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Accumulation of Dietary Cholesterol in Sitosterolemia Caused by Mutations in Adjacent ABC Transporters von Berge, Knut E., Tian, Hui, Graf, Gregory A., Yu, Liqing, Grishin, Nick V., Schultz, Joshua, Kwiterovich, Peter, Shan, Bei, Barnes, Robert, Hobbs, Helen H.

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Low LDL cholesterol in individuals of African descent resulting from frequent nonsense mutations in PCSK9 von Hobbs, Helen H, Cohen, Jonathan, Pertsemlidis, Alexander, Kotowski, Ingrid K, Graham, Randall, Garcia, Christine Kim

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A Sequence Variation (I148M) in PNPLA3 Associated with Nonalcoholic Fatty Liver Disease Disrupts Triglyceride Hydrolysis von He, Shaoqing, McPhaul, Christopher, Li, John Zhong, Garuti, Rita, Kinch, Lisa, Grishin, Nick V., Cohen, Jonathan C., Hobbs, Helen H.

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Multiple rare alleles contribute to low plasma levels of HDL cholesterol von Cohen, J.C, Kiss, R.S, Pertsemlidis, A, Marcel, Y.L, McPherson, R, Hobbs, H.H

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ANGPTL8/Betatrophin Does Not Control Pancreatic Beta Cell Expansion von Gusarova, Viktoria, Alexa, Corey A., Na, Erqian, Stevis, Panayiotis E., Xin, Yurong, Bonner-Weir, Susan, Cohen, Jonathan C., Hobbs, Helen H., Murphy, Andrew J., Yancopoulos, George D., Gromada, Jesper

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