Enantioselective Michael Reaction of Malonates to Nitroolefins Catalyzed by Bifunctional Organocatalysts von Okino, Tomotaka, Hoashi, Yasutaka, Takemoto, Yoshiji

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Reductively Cleavable Nanocaplets for siRNA Delivery by Template-Assisted Oxidative Polymerization von Hashim, P. K, Okuro, Kou, Sasaki, Shigekazu, Hoashi, Yasutaka, Aida, Takuzo

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Enantio- and Diastereoselective Michael Reaction of 1,3-Dicarbonyl Compounds to Nitroolefins Catalyzed by a Bifunctional Thiourea von Okino, Tomotaka, Hoashi, Yasutaka, Furukawa, Tomihiro, Xu, Xuenong, Takemoto, Yoshiji

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Anti-tumor activity of KNTC2 siRNA in orthotopic tumor model mice of hepatocellular carcinoma von Makita, Yukimasa, Murata, Shumpei, Katou, Yoshiki, Kikuchi, Kuniko, Uejima, Hiroshi, Teratani, Mika, Hoashi, Yasutaka, Kenjo, Eriya, Matsumoto, Satoru, Nogami, Masahiro, Otake, Kentaro, Kawamata, Yuji

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Enantioselective tandem Michael reaction to nitroalkene catalyzed by bifunctional thiourea: total synthesis of (−)-epibatidine von Hoashi, Yasutaka, Yabuta, Takaya, Yuan, Pei, Miyabe, Hideto, Takemoto, Yoshiji

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Thiourea-catalyzed nucleophilic addition of TMSCN and ketene silyl acetals to nitrones and aldehydes von Okino, Tomotaka, Hoashi, Yasutaka, Takemoto, Yoshiji

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Thiourea-Catalyzed Asymmetric Michael Addition of Activated Methylene Compounds to α,β-Unsaturated Imides:  Dual Activation of Imide by Intra- and Intermolecular Hydrogen Bonding... von Inokuma, Tsubasa, Hoashi, Yasutaka, Takemoto, Yoshiji

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Discovery of a Potent and Orally Bioavailable Melatonin Receptor Agonist von Hoashi, Yasutaka, Takai, Takafumi, Kosugi, Yohei, Nakashima, Masato, Nakayama, Masaharu, Hirai, Keisuke, Uchikawa, Osamu, Koike, Tatsuki

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Enantioselective Michael Addition to α,β-Unsaturated Imides Catalyzed by a Bifunctional Organocatalyst von Hoashi, Yasutaka, Okino, Tomotaka, Takemoto, Yoshiji

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Discovery of 1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazoles as novel class of corticotropin releasing factor 1 receptor antagonists von Kojima, Takuto, Mochizuki, Michiyo, Takai, Takafumi, Hoashi, Yasutaka, Morimoto, Sachie, Seto, Masaki, Nakamura, Minoru, Kobayashi, Katsumi, Sako, Yuu, Tanaka, Maiko, Kanzaki, Naoyuki, Kosugi, Yohei, Yano, Takahiko, Aso, Kazuyoshi

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Bifunctional thiourea-catalyzed enantioselective double Michael reaction of γ,δ-unsaturated β-ketoester to nitroalkene: asymmetric synthesis of (−)-epibatidine von Hoashi, Yasutaka, Yabuta, Takaya, Takemoto, Yoshiji

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Synthesis of pyrazolo[1,5-a]pyridines by thermal intramolecular cyclization von Hoashi, Yasutaka, Takai, Takafumi, Kotani, Etsuo, Koike, Tatsuki

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Discovery of novel 5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridine derivatives as γ-secretase modulators von Takai, Takafumi, Hoashi, Yasutaka, Tomata, Yoshihide, Morimoto, Sachie, Nakamura, Minoru, Watanabe, Tomomichi, Igari, Tomoko, Koike, Tatsuki

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1,6-Dihydro-2H-indeno[5,4-b]furan Derivatives: Design, Synthesis, and Pharmacological Characterization of a Novel Class of Highly Potent MT2-Selective Agonists von Koike, Tatsuki, Hoashi, Yasutaka, Takai, Takafumi, Nakayama, Masaharu, Yukuhiro, Nobuhito, Ishikawa, Takashi, Hirai, Keisuke, Uchikawa, Osamu

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Synthesis of a novel tricyclic 1,6,7,8-tetrahydro-2H-cyclopenta[b]furo[3,2-d]pyridine derivative, the 5-aza analog of ramelteon von Hoashi, Yasutaka, Takai, Takafumi, Koike, Tatsuki, Uchikawa, Osamu

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Synthesis of a Novel Series of Tricyclic Dihydrofuran Derivatives: Discovery of 8,9-Dihydrofuro[3,2-c]pyrazolo[1,5-a]pyridines as Melatonin Receptor (MT1/MT2) Ligands von Koike, Tatsuki, Takai, Takafumi, Hoashi, Yasutaka, Nakayama, Masaharu, Kosugi, Yohei, Nakashima, Masato, Yoshikubo, Shin-ichi, Hirai, Keisuke, Uchikawa, Osamu

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Synthesis of 4-aza analog of ramelteon: a novel tricyclic 1,6,7,8-tetrahydro-2H-cyclopenta[d]furo[2,3-b]pyridine derivative as melatonin receptor ligand von KOIKE, Tatsuki, HOASHI, Yasutaka, TAKAI, Takafumi, UCHIKAWA, Osamu

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Antitumor activity of kinetochore-associated protein 2 siRNA against lung cancer patient-derived tumor xenografts von Makita, Yukimasa, Teratani, Mika, Murata, Shumpei, Hoashi, Yasutaka, Matsumoto, Satoru, Kawamata, Yuji

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Design and synthesis of piperazine derivatives as a novel class of γ-secretase modulators that selectively lower Aβ42 production von Takai, Takafumi, Koike, Tatsuki, Honda, Eiji, Kajita, Yuichi, Nakamura, Minoru, Morimoto, Sachie, Hoashi, Yasutaka, Kamata, Makoto, Watanabe, Tomomichi, Igari, Tomoko, Terauchi, Jun

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Synthesis of 4-aza analog of ramelteon: a novel tricyclic 1,6,7,8-tetrahydro-2 H-cyclopenta[ d]furo[2,3- b]pyridine derivative as melatonin receptor ligand von Koike, Tatsuki, Hoashi, Yasutaka, Takai, Takafumi, Uchikawa, Osamu

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