Structural Basis for the Altered PAM Specificities of Engineered CRISPR-Cas9 von Hirano, Seiichi, Nishimasu, Hiroshi, Ishitani, Ryuichiro, Nureki, Osamu

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Engineered CRISPR-Cas9 nuclease with expanded targeting space von Nishimasu, Hiroshi, Shi, Xi, Ishiguro, Soh, Gao, Linyi, Hirano, Seiichi, Okazaki, Sae, Noda, Taichi, Abudayyeh, Omar O, Gootenberg, Jonathan S, Mori, Hideto, Oura, Seiya, Holmes, Benjamin, Tanaka, Mamoru, Seki, Motoaki, Hirano, Hisato, Aburatani, Hiroyuki, Ishitani, Ryuichiro, Ikawa, Masahito, Yachie, Nozomu, Zhang, Feng, Nureki, Osamu

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Structural insights into cGAMP degradation by Ecto-nucleotide pyrophosphatase phosphodiesterase 1 von Kato, Kazuki, Nishimasu, Hiroshi, Oikawa, Daisuke, Hirano, Seiichi, Hirano, Hisato, Kasuya, Go, Ishitani, Ryuichiro, Tokunaga, Fuminori, Nureki, Osamu

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Structural basis for the promiscuous PAM recognition by Corynebacterium diphtheriae Cas9 von Hirano, Seiichi, Abudayyeh, Omar O., Gootenberg, Jonathan S., Horii, Takuro, Ishitani, Ryuichiro, Hatada, Izuho, Zhang, Feng, Nishimasu, Hiroshi, Nureki, Osamu

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Real-space and real-time dynamics of CRISPR-Cas9 visualized by high-speed atomic force microscopy von Shibata, Mikihiro, Nishimasu, Hiroshi, Kodera, Noriyuki, Hirano, Seiichi, Ando, Toshio, Uchihashi, Takayuki, Nureki, Osamu

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Crystal structure of Drosophila Piwi von Yamaguchi, Sonomi, Oe, Akira, Nishida, Kazumichi M., Yamashita, Keitaro, Kajiya, Asako, Hirano, Seiichi, Matsumoto, Naoki, Dohmae, Naoshi, Ishitani, Ryuichiro, Saito, Kuniaki, Siomi, Haruhiko, Nishimasu, Hiroshi, Siomi, Mikiko C., Nureki, Osamu

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Applications of the CRISPR-Cas9 system in kidney research von Higashijima, Yoshiki, Hirano, Seiichi, Nangaku, Masaomi, Nureki, Osamu

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Augmented O‐GlcNAcylation of AMP‐activated kinase promotes the proliferation of LoVo cells, a colon cancer cell line von Ishimura, Emi, Nakagawa, Takatoshi, Moriwaki, Kazumasa, Hirano, Seiichi, Matsumori, Yoshinobu, Asahi, Michio

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Structural Basis for the Catalytic Mechanism of DncV, Bacterial Homolog of Cyclic GMP-AMP Synthase von Kato, Kazuki, Ishii, Ryohei, Hirano, Seiichi, Ishitani, Ryuichiro, Nureki, Osamu

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PAM-flexible Engineered FnCas9 variants for robust and ultra-precise genome editing and diagnostics von Acharya, Sundaram, Ansari, Asgar Hussain, Kumar Das, Prosad, Hirano, Seiichi, Aich, Meghali, Rauthan, Riya, Mahato, Sudipta, Maddileti, Savitri, Sarkar, Sajal, Kumar, Manoj, Phutela, Rhythm, Gulati, Sneha, Rahman, Abdul, Goel, Arushi, Afzal, C., Paul, Deepanjan, Agrawal, Trupti, Pulimamidi, Vinay Kumar, Jalali, Subhadra, Nishimasu, Hiroshi, Mariappan, Indumathi, Nureki, Osamu, Maiti, Souvik, Chakraborty, Debojyoti

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Use of endoscopic balloon dilation for benign esophageal stenosis in children: our 11 year experience von Osuga, Tatsuya, Ikura, Yoshihiro, Hasegawa, Kazunori, Hirano, Seiichi

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Cap-specific terminal N 6 -methylation of RNA by an RNA polymerase II-associated methyltransferase von Akichika, Shinichiro, Hirano, Seiichi, Shichino, Yuichi, Suzuki, Takeo, Nishimasu, Hiroshi, Ishitani, Ryuichiro, Sugita, Ai, Hirose, Yutaka, Iwasaki, Shintaro, Nureki, Osamu, Suzuki, Tsutomu

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Structural determinants of DNA cleavage by a CRISPR HNH-Cascade system von Hirano, Seiichi, Altae-Tran, Han, Kannan, Soumya, Macrae, Rhiannon K., Zhang, Feng

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Low-Dose Aspirin-Induced Gastroduodenal Mucosal Injury in Japanese Patients with Arteriosclerotic Disease von Tamura, Isamu, Fujita, Tsuyoshi, Tsumura, Hidetaka, Morita, Yoshinori, Yoshida, Masaru, Toyonaga, Takashi, Hirano, Seiichi, Inokuchi, Hideto, Kutsumi, Hiromu, Azuma, Takeshi

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Structure of the OMEGA nickase IsrB in complex with ωRNA and target DNA von Hirano, Seiichi, Kappel, Kalli, Altae-Tran, Han, Faure, Guilhem, Wilkinson, Max E., Kannan, Soumya, Demircioglu, F. Esra, Yan, Rui, Shiozaki, Momoko, Yu, Zhiheng, Makarova, Kira S., Koonin, Eugene V., Macrae, Rhiannon K., Zhang, Feng

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Molecular mechanism of CRISPR von Nureki, Osamu, Hirano, Hisato, Hirano, Seiichi, Yamano, Takashi, Nishimasu, Hiroshi

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Augmented O ‐Glc NA cylation of AMP ‐activated kinase promotes the proliferation of LoVo cells, a colon cancer cell line von Ishimura, Emi, Nakagawa, Takatoshi, Moriwaki, Kazumasa, Hirano, Seiichi, Matsumori, Yoshinobu, Asahi, Michio

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Cap-specific terminal N6-methylation of RNA by an RNA polymerase II–associated methyltransferase von Akichika Shinichiro, Hirano Seiichi, Shichino Yuichi, Suzuki, Takeo, Nishimasu Hiroshi, Ishitani Ryuichiro, Sugita Ai, Hirose Yutaka, Iwasaki Shintaro, Nureki Osamu, Suzuki, Tsutomu

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Sa2077 Usefulness of Endoscopic Balloon Dilation for Esophageal Stenosis in Children von Osuga, Tatsuya, Kakuyama, Saori, Nakajima, Eishin, Kadota, Chikara, Hasegawa, Kazunori, Hirano, Seiichi

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Significance of liver biopsy for the evaluation of methotrexate-induced liver damage in patients with rheumatoid arthritis von Osuga, Tatsuya, Ikura, Yoshihiro, Kadota, Chikara, Hirano, Seiichi, Iwai, Yasuhiro, Hayakumo, Takanobu

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