Multiplatform genomic profiling and magnetic resonance imaging identify mechanisms underlying intratumor heterogeneity in meningioma von Magill, Stephen T., Vasudevan, Harish N., Seo, Kyounghee, Villanueva-Meyer, Javier E., Choudhury, Abrar, John Liu, S., Pekmezci, Melike, Findakly, Sarah, Hilz, Stephanie, Lastella, Sydney, Demaree, Benjamin, Braunstein, Steve E., Bush, Nancy Ann Oberheim, Aghi, Manish K., Theodosopoulos, Philip V., Sneed, Penny K., Abate, Adam R., Berger, Mitchel S., McDermott, Michael W., Lim, Daniel A., Ullian, Erik M., Costello, Joseph F., Raleigh, David R.

Volltext

Aberrant gene expression by Sertoli cells in infertile men with Sertoli cell-only syndrome von Paduch, Darius A, Hilz, Stephanie, Grimson, Andrew, Schlegel, Peter N, Jedlicka, Anne E, Wright, William W

Volltext

Dgcr8 and Dicer are essential for sex chromosome integrity during meiosis in males von Modzelewski, Andrew J, Hilz, Stephanie, Crate, Elizabeth A, Schweidenback, Caterina T H, Fogarty, Elizabeth A, Grenier, Jennifer K, Freire, Raimundo, Cohen, Paula E, Grimson, Andrew

Volltext

Multiplatform Molecular Profiling Reveals Epigenomic Intratumor Heterogeneity in Ependymoma von Liu, S. John, Magill, Stephen T., Vasudevan, Harish N., Hilz, Stephanie, Villanueva-Meyer, Javier E., Lastella, Sydney, Daggubati, Vikas, Spatz, Jordan, Choudhury, Abrar, Orr, Brent A., Demaree, Benjamin, Seo, Kyounghee, Ferris, Sean P., Abate, Adam R., Oberheim Bush, Nancy Ann, Bollen, Andrew W., McDermott, Michael W., Costello, Joseph F., Raleigh, David R.

Volltext

370 Tumor-wide neoantigen-specific T-cells infiltrating mutant IDH1 low-grade gliomas and persisting in peripheral blood allow for personalized TCR-based immunotherapies von Kwok, Darwin, Zhang, Michael, Wang, Cliff, Stevers, Nicholas, Borrman, Tyler, Pan, Zheng, Yuen, Benjamin, Peng, Songming, Nguyen, Diana, Martin, Michael, Hong, Chibo, Hilz, Stephanie, Phillips, Joanna, Shai, Anny, Oberheim Bush, Nancy Ann, Hervey-Jumper, Shawn L, McDermott, Michael, Mandl, Stefanie, Okada, Hideho, Costello, Joseph

Volltext

The roles of microRNAs and siRNAs in mammalian spermatogenesis von Hilz, Stephanie, Modzelewski, Andrew J, Cohen, Paula E, Grimson, Andrew

Volltext

Neoadjuvant atezolizumab for resectable non-small cell lung cancer: an open-label, single-arm phase II trial von Chaft, Jamie E., Oezkan, Filiz, Kris, Mark G., Bunn, Paul A., Wistuba, Ignacio I., Kwiatkowski, David J., Owen, Dwight H., Tang, Yan, Johnson, Bruce E., Lee, Jay M., Lozanski, Gerard, Pietrzak, Maciej, Seweryn, Michal, Byun, Woo Yul, Schulze, Katja, Nicholas, Alan, Johnson, Ann, Grindheim, Jessica, Hilz, Stephanie, Shames, David S., Rivard, Chris, Toloza, Eric, Haura, Eric B., McNamee, Ciaran J., Patterson, G. Alexander, Waqar, Saiama N., Rusch, Valerie W., Carbone, David P.

Volltext

Novel Transcriptomics Based Stratification Approach Using the Commpass Dataset Reveals Mechanistic Insights into Current and Upcoming MM Therapies von Hamidi, Habib, Sumiyoshi, Teiko, Dos Santos, Cedric E., Tracy, Samuel, Cho, Hearn J., Hilz, Stephanie, Chopra, Vivek S.

Volltext

CSIG-07. HYPERCELLULAR NODULES IN OLIGODENDROGLIOMA REPRESENT POCKETS OF PROLIFERATIVE STEM-LIKE TUMOR CELLS von Liu, Mengyi, Abramson, Karen, Hocke, Emily, Hilz, Stephanie, Costello, Joseph, McLendon, Roger, Ashley, David, Gregory, Simon, Lopez, Giselle

Volltext

Exploratory biomarker analysis of acelERA breast cancer (BC): Phase II study of giredestrant vs. physician’s choice of endocrine therapy (PCET) for previously treated, estrogen rec... von Collier, Ann, Chavez Mac Gregor, Mariana, Hilz, Stephanie, Bardia, Aditya, Sohn, Joohyuk, Martin, Miguel, Lim, Elgene, Martinalbo, Jorge, Pérez-Moreno, Pablo Diego, Moore, Heather M.

Volltext

Temozolomide-induced hypermutation is associated with distant recurrence and reduced survival after high-grade transformation of low-grade IDH-mutant gliomas von Yu, Yao, Villanueva-Meyer, Javier, Grimmer, Matthew R, Hilz, Stephanie, Solomon, David A, Choi, Serah, Wahl, Michael, Mazor, Tali, Hong, Chibo, Shai, Anny, Phillips, Joanna J, Wainer, Bruce H, McDermott, Michael, Haas-Kogan, Daphne, Taylor, Jennie W, Butowski, Nicholas, Clarke, Jennifer L, Berger, Mitchel S, Molinaro, Annette M, Chang, Susan M, Costello, Joseph F, Oberheim Bush, Nancy Ann

Volltext

PI3K/AKT/mTOR signaling pathway activity in IDH-mutant diffuse glioma and clinical implications von Mohamed, Esraa, Kumar, Anupam, Zhang, Yalan, Wang, Albert S, Chen, Katharine, Lim, Yunita, Shai, Anny, Taylor, Jennie W, Clarke, Jennifer, Hilz, Stephanie, Berger, Mitchel S, Solomon, David A, Costello, Joseph F, Molinaro, Annette M, Phillips, Joanna J

Volltext

EPCO-31. EPIGENOMIC INTRATUMORAL HETEROGENEITY OF GLIOBLASTOMA IN THREE-DIMENSIONAL SPACE von Mathur, Radhika, Iyyanki, Sriranga, Hilz, Stephanie, Hong, Chibo, Phillips, Joanna, Chang, Susan, Yue, Feng, Costello, Joseph

Volltext

Glioblastoma evolution and heterogeneity from a 3D whole-tumor perspective von Mathur, Radhika, Wang, Qixuan, Schupp, Patrick G., Nikolic, Ana, Hilz, Stephanie, Hong, Chibo, Grishanina, Nadia R., Kwok, Darwin, Stevers, Nicholas O., Jin, Qiushi, Youngblood, Mark W., Stasiak, Lena Ann, Hou, Ye, Wang, Juan, Yamaguchi, Takafumi N., Lafontaine, Marisa, Shai, Anny, Smirnov, Ivan V., Solomon, David A., Chang, Susan M., Hervey-Jumper, Shawn L., Berger, Mitchel S., Lupo, Janine M., Okada, Hideho, Phillips, Joanna J., Boutros, Paul C., Gallo, Marco, Oldham, Michael C., Yue, Feng, Costello, Joseph F.

Volltext

Quantitative Assessment of Preanalytic Variables on Clinical Evaluation of PI3/AKT/mTOR Signaling Activity in Diffuse Glioma von Beccari, Sol, Mohamed, Esraa, Voong, Viva, Hilz, Stephanie, Lafontaine, Marisa, Shai, Anny, Lim, Yunita, Martinez, Jerry, Switzman, Benjamin, Yu, Ryon L., Lupo, Janine M., Chang, Edward F., Hervey-Jumper, Shawn L., Berger, Mitchel S., Costello, Joseph F., Phillips, Joanna J.

Volltext

Artificial Intelligence–Powered Assessment of Pathologic Response to Neoadjuvant Atezolizumab in Patients With NSCLC: Results From the LCMC3 Study von Dacic, Sanja, Travis, William D., Giltnane, Jennifer M., Kos, Filip, Abel, John, Hilz, Stephanie, Fujimoto, Junya, Sholl, Lynette, Ritter, Jon, Khalil, Farah, Liu, Yi, Taylor-Weiner, Amaro, Resnick, Murray, Yu, Hui, Hirsch, Fred R., Bunn, Paul A., Carbone, David P., Rusch, Valerie, Kwiatkowski, David J., Johnson, Bruce E., Lee, Jay M., Hennek, Stephanie R., Wapinski, Ilan, Nicholas, Alan, Johnson, Ann, Schulze, Katja, Kris, Mark G., Wistuba, Ignacio I.

Volltext

Whole tumor analysis reveals early origin of the TERT promoter mutation and intercellular heterogeneity in TERT expression von Appin, Christina L, Hong, Chibo, Suwala, Abigail K, Hilz, Stephanie, Mathur, Radhika, Solomon, David A, Smirnov, Ivan V, Stevers, Nicholas O, Shai, Anny, Wang, Albert, Berger, Mitchel S, Chang, Susan M, Phillips, Joanna J, Costello, Joseph F

Volltext

PATH-28. RE-DEFINING CLONALITY OF THE TERT PROMOTER MUTATION WITH DEEP SEQUENCING AND MAXIMAL SAMPLING OF NEWLY DIAGNOSED AND RECURRENT GBM AND OLIGODENDROGLIOMA von Appin, Christina, Suwala, Abigail K, Hilz, Stephanie, Mathur, Radhika, Smirnov, Ivan, Hong, Chibo, Stevers, Nicholas, Shai, Anny, Berger, Mitchel, Chang, Susan, Phillips, Joanna, Costello, Joseph

Volltext

Intratumor and informatic heterogeneity influence meningioma molecular classification von Vasudevan, Harish N., Choudhury, Abrar, Hilz, Stephanie, Villanueva-Meyer, Javier E., Chen, William C., Lucas, Calixto-Hope G., Braunstein, Steve E., Oberheim Bush, Nancy Ann, Butowski, Nicholas, Pekmezci, Melike, McDermott, Michael W., Perry, Arie, Solomon, David A., Magill, Stephen T., Raleigh, David R.

Volltext

AGO4 Regulates Entry into Meiosis and Influences Silencing of Sex Chromosomes in the Male Mouse Germline von Modzelewski, Andrew J., Holmes, Rebecca J., Hilz, Stephanie, Grimson, Andrew, Cohen, Paula E.

Volltext