The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism von Murphy, James M., Czabotar, Peter E., Hildebrand, Joanne M., Lucet, Isabelle S., Zhang, Jian-Guo, Alvarez-Diaz, Silvia, Lewis, Rowena, Lalaoui, Najoua, Metcalf, Donald, Webb, Andrew I., Young, Samuel N., Varghese, Leila N., Tannahill, Gillian M., Hatchell, Esme C., Majewski, Ian J., Okamoto, Toru, Dobson, Renwick C.J., Hilton, Douglas J., Babon, Jeffrey J., Nicola, Nicos A., Strasser, Andreas, Silke, John, Alexander, Warren S.

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scPipe: A flexible R/Bioconductor preprocessing pipeline for single-cell RNA-sequencing data von Tian, Luyi, Su, Shian, Dong, Xueyi, Amann-Zalcenstein, Daniela, Biben, Christine, Seidi, Azadeh, Hilton, Douglas J, Naik, Shalin H, Ritchie, Matthew E

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NLRP1 Inflammasome Activation Induces Pyroptosis of Hematopoietic Progenitor Cells von Masters, Seth L., Gerlic, Motti, Metcalf, Donald, Preston, Simon, Pellegrini, Marc, O’Donnell, Joanne A., McArthur, Kate, Baldwin, Tracey M., Chevrier, Stephane, Nowell, Cameron J., Cengia, Louise H., Henley, Katya J., Collinge, Janelle E., Kastner, Daniel L., Feigenbaum, Lionel, Hilton, Douglas J., Alexander, Warren S., Kile, Benjamin T., Croker, Ben A.

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Suppression of cytokine signaling: The SOCS perspective von Linossi, Edmond M, Babon, Jeffrey J, Hilton, Douglas J, Nicholson, Sandra E

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SmcHD1, containing a structural-maintenance-of-chromosomes hinge domain, has a critical role in X inactivation von Blewitt, Marnie E, Gendrel, Anne-Valerie, Pang, Zhenyi, Sparrow, Duncan B, Whitelaw, Nadia, Craig, Jeffrey M, Apedaile, Anwyn, Hilton, Douglas J, Dunwoodie, Sally L, Brockdorff, Neil, Kay, Graham F, Whitelaw, Emma

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Haemopedia RNA-seq: a database of gene expression during haematopoiesis in mice and humans von Choi, Jarny, Baldwin, Tracey M, Wong, Mae, Bolden, Jessica E, Fairfax, Kirsten A, Lucas, Erin C, Cole, Rebecca, Biben, Christine, Morgan, Clare, Ramsay, Kerry A, Ng, Ashley P, Kauppi, Maria, Corcoran, Lynn M, Shi, Wei, Wilson, Nick, Wilson, Michael J, Alexander, Warren S, Hilton, Douglas J, de Graaf, Carolyn A

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Short-term particulate matter contamination severely compromises insect antennal olfactory perception von Wang, Qike, Liu, Genting, Yan, Liping, Xu, Wentian, Hilton, Douglas J., Liu, Xianhui, Pei, Wenya, Li, Xinyu, Wu, Jinbiao, Zhao, Haifeng, Zhang, Dong, Elgar, Mark A.

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Antennal scales improve signal detection efficiency in moths von Wang, Qike, Shang, Yidan, Hilton, Douglas S., Inthavong, Kiao, Zhang, Dong, Elgar, Mark A.

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The transcription factor Erg is essential for definitive hematopoiesis and the function of adult hematopoietic stem cells von Loughran, Stephen J, Kruse, Elizabeth A, Hacking, Douglas F, de Graaf, Carolyn A, Hyland, Craig D, Willson, Tracy A, Henley, Katya J, Ellis, Sarah, Voss, Anne K, Metcalf, Donald, Hilton, Douglas J, Alexander, Warren S, Kile, Benjamin T

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ChIP-seq analysis reveals distinct H3K27me3 profiles that correlate with transcriptional activity von Young, Matthew D., Willson, Tracy A., Wakefield, Matthew J., Trounson, Evelyn, Hilton, Douglas J., Blewitt, Marnie E., Oshlack, Alicia, Majewski, Ian J.

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Inhibitors of Cytokine Signal Transduction von Wormald, Samuel, Hilton, Douglas J.

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Dissecting the molecular control of Interleukin 6 signaling using the M1 cell line von Morris, Rhiannon, Hilton, Douglas J., Jarratt, Andrew, Babon, Jeffrey J.

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A mouse model of harlequin ichthyosis delineates a key role for Abca12 in lipid homeostasis von Smyth, Ian, Hacking, Douglas F, Hilton, Adrienne A, Mukhamedova, Nigora, Meikle, Peter J, Ellis, Sarah, Satterley, Keith, Slattery, Keith, Collinge, Janelle E, de Graaf, Carolyn A, Bahlo, Melanie, Sviridov, Dmitri, Kile, Benjamin T, Hilton, Douglas J

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Mpl expression on megakaryocytes and platelets is dispensable for thrombopoiesis but essential to prevent myeloproliferation von Ng, Ashley P., Kauppi, Maria, Metcalf, Donald, Hyland, Craig D., Josefsson, Emma C., Lebois, Marion, Zhang, Jian-Guo, Baldwin, Tracey M., Di Rago, Ladina, Hilton, Douglas J., Alexander, Warren S.

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The role of suppressors of cytokine signaling (SOCS) proteins in regulation of the immune response von Alexander, Warren S, Hilton, Douglas J

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Membrane budding is a major mechanism of in vivo platelet biogenesis von Potts, Kathryn S, Farley, Alison, Dawson, Caleb A, Rimes, Joel, Biben, Christine, de Graaf, Carolyn, Potts, Margaret A, Stonehouse, Olivia J, Carmagnac, Amandine, Gangatirkar, Pradnya, Josefsson, Emma C, Anttila, Casey, Amann-Zalcenstein, Daniela, Naik, Shalin, Alexander, Warren S, Hilton, Douglas J, Hawkins, Edwin D, Taoudi, Samir

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Alpha Interferon Induces Long-Lasting Refractoriness of JAK-STAT Signaling in the Mouse Liver through Induction of USP18/UBP43 von Sarasin-Filipowicz, Magdalena, Wang, Xueya, Yan, Ming, Duong, Francois H. T., Poli, Valeria, Hilton, Douglas J., Zhang, Dong-Er, Heim, Markus H.

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Genome-wide binding and mechanistic analyses of Smchd1-mediated epigenetic regulation von Chen, Kelan, Jiang Hu, Darcy L. Moore, Ruijie Liu, Sarah A. Kessans, Kelsey Breslin, Isabelle S. Lucet, Andrew Keniry, Huei San Leong, Clare L. Parish, Douglas J. Hilton, Richard J. L. F. Lemmers, Silvère M. van der Maarel, Peter E. Czabotar, Renwick C. J. Dobson, Matthew E. Ritchie, Graham F. Kay, James M. Murphy, Marnie E. Blewitt

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BAF complex-mediated chromatin relaxation is required for establishment of X chromosome inactivation von Keniry, Andrew, Jansz, Natasha, Gearing, Linden J., Wanigasuriya, Iromi, Chen, Joseph, Nefzger, Christian M., Hickey, Peter F., Gouil, Quentin, Liu, Joy, Breslin, Kelsey A., Iminitoff, Megan, Beck, Tamara, Tapia del Fierro, Andres, Whitehead, Lachlan, Jarratt, Andrew, Kinkel, Sarah A., Taberlay, Phillippa C., Willson, Tracy, Pakusch, Miha, Ritchie, Matthew E., Hilton, Douglas J., Polo, Jose M., Blewitt, Marnie E.

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PU.1 Is Required for the Developmental Progression of Multipotent Progenitors to Common Lymphoid Progenitors von Pang, Swee Heng Milon, de Graaf, Carolyn A, Hilton, Douglas J, Huntington, Nicholas D, Carotta, Sebastian, Wu, Li, Nutt, Stephen L

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