AZD8931, an Equipotent, Reversible Inhibitor of Signaling by Epidermal Growth Factor Receptor, ERBB2 (HER2), and ERBB3: A Unique Agent for Simultaneous ERBB Receptor Blockade in Ca... von HICKINSON, D. Mark, KLINOWSKA, Teresa, MILLS, Elizabeth, GROSIOS, Konstantina, SMITH, Paul, BARLAAM, Bernard, WILKINSON, Robert W, OGILVIE, Donald, SPEAKE, Georgina, VINCENT, John, TRIGWELL, Cath, ANDERTON, Judith, BECK, Sarah, MARSHALL, Gayle, DAVENPORT, Sara, CALLIS, Rowena

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Preclinical anticancer activity of the potent, oral Src inhibitor AZD0530 von Green, Tim P., Fennell, Mike, Whittaker, Robin, Curwen, Jon, Jacobs, Vivien, Allen, Jack, Logie, Armelle, Hargreaves, Judith, Hickinson, D. Mark, Wilkinson, Robert W., Elvin, Paul, Boyer, Brigitte, Carragher, Neil, Plé, Patrick A., Bermingham, Alun, Holdgate, Geoffrey A., Ward, Walter H.J., Hennequin, Laurent F., Davies, Barry R., Costello, Gerard F.

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Epidermal growth factor receptor tyrosine kinase inhibitors: similar but different? von Rukazenkov, Yuri, Speake, Georgina, Marshall, Gayle, Anderton, Judith, Davies, Barry R, Wilkinson, Robert W, Mark Hickinson, D, Swaisland, Alan

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Novel 3-alkoxy-1H-pyrazolo[3,4-d]pyrimidines as EGFR and erbB2 receptor tyrosine kinase inhibitors von DUCRAY, Richard, BALLARD, Peter, BARLAAM, Bernard C, HICKINSON, Mark D, KETTLE, Jason G, OGILVIE, Donald J, TRIGWELL, Catherine B

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Discovery of AZD8931, an Equipotent, Reversible Inhibitor of Signaling by EGFR, HER2, and HER3 Receptors von Barlaam, Bernard, Anderton, Judith, Ballard, Peter, Bradbury, Robert H, Hennequin, Laurent F. A, Hickinson, D. Mark, Kettle, Jason G, Kirk, George, Klinowska, Teresa, Lambert-van der Brempt, Christine, Trigwell, Cath, Vincent, John, Ogilvie, Donald

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Vandetanib inhibits both VEGFR-2 and EGFR signalling at clinically relevant drug levels in preclinical models of human cancer von BRAVE, Sandra R, ODEDRA, Rajesh, WAINWRIGHT, Anna, LOVICK, Susan C, MARK HICKINSON, D, WILKINSON, Robert W, BARRY, Simon T, SPEAKE, Georgina, RYAN, Anderson J, JAMES, Neil H, SMITH, NeilR, MARSHALL, Gayle B, ACHESON, Kerry L, BAKER, Dawn, HOWARD, Zoe, AY JACKSON, Lyns, RATCLIFFE, Kirsty

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5-Substituted 4-anilinoquinazolines as potent, selective and orally active inhibitors of erbB2 receptor tyrosine kinase von Ballard, Peter, Bradbury, Robert H., Hennequin, Laurent F.A., Hickinson, D. Mark, Johnson, Paul D., Kettle, Jason G., Klinowska, Teresa, Morgentin, Remy, Ogilvie, Donald J., Olivier, Annie

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Neutral 5-substituted 4-anilinoquinazolines as potent, orally active inhibitors of erbB2 receptor tyrosine kinase von Ballard, Peter, Barlaam, Bernard C., Bradbury, Robert H., Dishington, Allan, Hennequin, Laurent F.A., Hickinson, D. Mark, Hollingsworth, Ian M., Kettle, Jason G., Klinowska, Teresa, Ogilvie, Donald J., Pearson, Stuart E., Scott, James S., Suleman, Abid, Whittaker, Robin, Williams, Emma J., Wood, Robin, Wright, Lindsay

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Src Family Kinase Inhibitor Saracatinib (AZD0530) Impairs Oxaliplatin Uptake in Colorectal Cancer Cells and Blocks Organic Cation Transporters von MORROW, Christopher J, GHATTAS, Mohammad, SMITH, Christopher, BÖNISCH, Heinz, BRYCE, Richard A, HICKINSON, D. Mark, GREEN, Tim P, DIVE, Caroline

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A new series of neutral 5-substituted 4-anilinoquinazolines as potent, orally active inhibitors of erbB2 receptor tyrosine kinase von Barlaam, Bernard, Ballard, Peter, Bradbury, Robert H., Ducray, Richard, Germain, Hervé, Hickinson, D. Mark, Hudson, Kevin, Kettle, Jason G., Klinowska, Teresa, Magnien, Françoise, Ogilvie, Donald J., Olivier, Annie, Pearson, Stuart E., Scott, James S., Suleman, Abid, Trigwell, Cath B., Vautier, Michel, Whittaker, Robin D., Wood, Robin

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Identification of Biomarkers in Human Head and Neck Tumor Cell Lines That Predict For In Vitro Sensitivity to Gefitinib von Hickinson, D. Mark, Marshall, Gayle B., Beran, Garry J., Varella-Garcia, Marileila, Mills, Elizabeth A., South, Marie C., Cassidy, Andrew M., Acheson, Kerry L, McWalter, Gael, McCormack, Rose M., Bunn, Paul A., French, Tim, Graham, Alex, Holloway, Brian R., Hirsch, Fred R., Speake, Georgina

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Inhibitors of epidermal growth factor receptor tyrosine kinase: Novel C-5 substituted anilinoquinazolines designed to target the ribose pocket von Ballard, Peter, Bradbury, Robert H., Harris, Craig S., Hennequin, Laurent F.A., Hickinson, Mark, Johnson, Paul D., Kettle, Jason G., Klinowska, Teresa, Leach, Andrew G., Morgentin, Remy, Pass, Martin, Ogilvie, Donald J., Olivier, Annie, Warin, Nicolas, Williams, Emma J.

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Inhibitors of epidermal growth factor receptor tyrosine kinase: Optimisation of potency and in vivo pharmacokinetics von Ballard, Peter, Bradbury, Robert H., Harris, Craig S., Hennequin, Laurent F.A., Hickinson, Mark, Kettle, Jason G., Kendrew, Jane, Klinowska, Teresa, Ogilvie, Donald J., Pearson, Stuart E., Williams, Emma J., Wilson, Ingrid

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Novel 3-alkoxy-1 H-pyrazolo[3,4- d]pyrimidines as EGFR and erbB2 receptor tyrosine kinase inhibitors von Ducray, Richard, Ballard, Peter, Barlaam, Bernard C., Hickinson, Mark D., Kettle, Jason G., Ogilvie, Donald J., Trigwell, Catherine B.

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HUMAN ANTIBODIES TO ERBB 2 von Dong, Jianying, Hickinson, Mark, Kang, Jaspal Singh, Foltz, Ian, Cartlidge, Susan Ann

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HUMAN ANTIBODIES TO ERBB 2 von Cartlidge Susan Ann, Dong Jianying, Kang Jaspal Singh, Foltz Ian, Hickinson Mark

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HUMAN ANTIBODIES TO ERBB 2 von FOLTZ, IAN, CARTLIDGE, SUSAN ANN, HICKINSON, MARK, KANG, JASPAL SINGH, DONG, JIANYING

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HUMAN ANTIBODIES TO ERBB 2 von Dong, Jianying, Hickinson, Mark, Kang, Jaspal Singh, Foltz, Ian, Cartlidge, Susan Ann

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HUMANE ANTISTOFFER MOD ERBB 2 von Dong, Jianying, Hickinson, Mark, Kang, Jaspal Singh, Foltz, Ian, Cartlidge, Susan Ann

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HUMAN ANTIBODIES TO ERBB 2 von IAN FOLTZ, JASPAL SINGH KANG, JIANYING DONG, SUSAN ANN CARTLIDGE, MARK HICKINSON

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