Activity‐based probes for the ubiquitin conjugation–deconjugation machinery: new chemistries, new tools, and new insights von Hewings, David S., Flygare, John A., Bogyo, Matthew, Wertz, Ingrid E.

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Progress in the Development and Application of Small Molecule Inhibitors of Bromodomain–Acetyl-lysine Interactions von Hewings, David S, Rooney, Timothy P. C, Jennings, Laura E, Hay, Duncan A, Schofield, Christopher J, Brennan, Paul E, Knapp, Stefan, Conway, Stuart J

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Small Molecule Inhibitors of Bromodomain–Acetyl-lysine Interactions von Brand, Michael, Measures, Angelina M, Wilson, Brian G, Cortopassi, Wilian A, Alexander, Rikki, Höss, Matthias, Hewings, David S, Rooney, Timothy P. C, Paton, Robert S, Conway, Stuart J

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Preclinical Characterization of a Next-Generation Brain Permeable, Paradox Breaker BRAF Inhibitor von Wichmann, Jürgen, Rynn, Caroline, Friess, Thomas, Petrig-Schaffland, Jeannine, Kornacker, Martin, Handl, Cornelia, Emmenegger, Jasmin, Eckmann, Jan, Herting, Frank, Frances, Nicolas, Hunziker, Daniel, Krummenacher, Daniela, Rüttinger, Dominik, Ribeiro, Alison, Bacac, Marina, Brigo, Alessandro, Hewings, David S, Dummer, Reinhard, Levesque, Mitchell P, Schnetzler, Gabriel, Martoglio, Bruno, Bischoff, James R, Pettazzoni, Piergiorgio

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Discovery of Orally Available and Brain Penetrant AEP Inhibitors von Krummenacher, Daniela, He, Weiping, Kuhn, Bernd, Schnider, Christian, Beurier, Angélica, Brom, Virginie, Sivasothy, Thulase, Marty, Christine, Tosstorff, Andreas, Hewings, David S., Mesch, Stefanie, Pinard, Emmanuel, Brändlin, Mathis, Hochstrasser, Remo, Westwood, Paul, Rothe, Judith, Kronenberger, Alexandra, Morandi, Federica, Gutbier, Simon, Schuler, Angelika, Heer, Dominik, Gloria, Ludivine Esteves, Joedicke, Lisa, Rudolph, Markus G., Müller, Lutz, Grüninger, Fiona, Baumann, Karlheinz, Kaniyappan, Senthilvelrajan, Manevski, Nenad, Bartels, Björn

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BET bromodomain ligands: Probing the WPF shelf to improve BRD4 bromodomain affinity and metabolic stability von Jennings, Laura E., Schiedel, Matthias, Hewings, David S., Picaud, Sarah, Laurin, Corentine M.C., Bruno, Paul A., Bluck, Joseph P., Scorah, Amy R., See, Larissa, Reynolds, Jessica K., Moroglu, Mustafa, Mistry, Ishna N., Hicks, Amy, Guzanov, Pavel, Clayton, James, Evans, Charles N.G., Stazi, Giulia, Biggin, Philip C., Mapp, Anna K., Hammond, Ester M., Humphreys, Philip G., Filippakopoulos, Panagis, Conway, Stuart J.

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Expanding the repertoire of GalNAc analogues for cell-specific bioorthogonal tagging of glycoproteins von Zafar, Abdul, Sridhar, Sandhya, Bineva-Todd, Ganka, Cioce, Anna, Abdulla, Nadia, Chang, Vincent, Malaker, Stacy A, Hewings, David S, Schumann, Benjamin

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Organocatalytic removal of formaldehyde adducts from RNA and DNA bases von Karmakar, Saswata, Harcourt, Emily M., Hewings, David S., Scherer, Florian, Lovejoy, Alexander F., Kurtz, David M., Ehrenschwender, Thomas, Barandun, Luzi J., Roost, Caroline, Alizadeh, Ash A., Kool, Eric T.

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Isoxazole-Derived Amino Acids are Bromodomain-Binding Acetyl-Lysine Mimics: Incorporation into Histone H4 Peptides and Histone H3 von Sekirnik (née Measures), Angelina R., Hewings, David S., Theodoulou, Natalie H., Jursins, Lukass, Lewendon, Katie R., Jennings, Laura E., Rooney, Timothy P. C., Heightman, Tom D., Conway, Stuart J.

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Fragment-Based Identification of Ligands for Bromodomain-Containing Factor 3 of Trypanosoma cruzi von Laurin, Corentine M. C, Bluck, Joseph P, Chan, Anthony K. N, Keller, Michelle, Boczek, Andrew, Scorah, Amy R, See, K. F. Larissa, Jennings, Laura E, Hewings, David S, Woodhouse, Fern, Reynolds, Jessica K, Schiedel, Matthias, Humphreys, Philip G, Biggin, Philip C, Conway, Stuart J

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Ammonium-Directed Olefinic Epoxidation: Kinetic and Mechanistic Insights von Brennan, Méabh B, Claridge, Timothy D. W, Compton, Richard G, Davies, Stephen G, Fletcher, Ai M, Henstridge, Martin C, Hewings, David S, Kurosawa, Wataru, Lee, James A, Roberts, Paul M, Schoonen, Anne K, Thomson, James E

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Structured approach to maintenance and modification of a railway traction IEC 61850 substation automation system von Hewings, David, Poczapsky, Andrea

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Isoxazole-Derived Amino Acids are Bromodomain-Binding Acetyl-Lysine Mimics: Incorporation into Histone H4 Peptides and Histone H3 von Sekirnik (née Measures), Angelina R., Hewings, David S., Theodoulou, Natalie H., Jursins, Lukass, Lewendon, Katie R., Jennings, Laura E., Rooney, Timothy P. C., Heightman, Tom D., Conway, Stuart J.

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Preclinical Characterization of a Next-Generation Brain Permeable, Paradox Breaker BRAF Inhibitor von Wichmann, Jürgen, Rynn, Caroline, Friess, Thomas, Petrig-Schaffland, Jeannine, Kornacker, Martin, Handl, Cornelia, Emmenegger, Jasmin, Eckmann, Jan, Herting, Frank, Frances, Nicolas, Hunziker, Daniel, Krummenacher, Daniela, Rüttinger, Dominik, Ribeiro, Alison, Bacac, Marina, Brigo, Alessandro, Hewings, David S, Dummer, Reinhard, Levesque, Mitchell P, Schnetzler, Gabriel, Martoglio, Bruno, Bischoff, James R, Pettazzoni, Piergiorgio

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Erratum: Corrigendum: Organocatalytic removal of formaldehyde adducts from RNA and DNA bases von Karmakar, Saswata, Harcourt, Emily M., Hewings, David S., Scherer, Florian, Lovejoy, Alexander F., Kurtz, David M., Ehrenschwender, Thomas, Barandun, Luzi J., Roost, Caroline, Alizadeh, Ash A., Kool, Eric T.

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The Synthesis and Crystal Structures of Two Hydrogen-Bonded N-Oxides von Brock, E. Anne, Davies, Stephen G., Hewings, David S., Lee, James A., Thompson, Amber L., Thomson, James E.

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Synthesis and Crystal Structures of (RS,RS,RS)- and (1RS,2RS,3SR)-3-(N-Methylamino)cyclohexane-1,2-diol von Davies, Stephen G., Hewings, David S., Kurosawa, Wataru, Lee, James A., Roberts, Paul M., Thompson, Amber L., Thomson, James E.

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Synthesis and Crystal Structures of N-Aryl-N-methylaminocyclohexanols von Cresswell, Alexander J., Davies, Stephen G., Hewings, David S., Kurosawa, Wataru, Lee, James A., Morris, Melloney J., Roberts, Paul M., Thompson, Amber L., Thomson, James E.

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The design and synthesis of 5- and 6-isoxazolylbenzimidazoles as selective inhibitors of the BET bromodomainsThis article is part of a MedChemComm 'New Talents' issue highlighting... von Hay, Duncan, Fedorov, Oleg, Filippakopoulos, Panagis, Martin, Sarah, Philpott, Martin, Picaud, Sarah, Hewings, David S, Uttakar, Sagar, Heightman, Tom D, Conway, Stuart J, Knapp, Stefan, Brennan, Paul E

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NEW METHYLQUINAZOLINONE DERIVATIVES von HEWINGS, David Stephen, DOLENTE, Cosimo, WICHMANN, Juergen, KRUMMENACHER, Daniela, PETTAZZONI, Piergiorgio Francesco Tommaso, HUNZIKER, Daniel

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