Lysine-specific demethylase 1 restricts hematopoietic progenitor proliferation and is essential for terminal differentiation von Sprüssel, A, Schulte, J H, Weber, S, Necke, M, Händschke, K, Thor, T, Pajtler, K W, Schramm, A, König, K, Diehl, L, Mestdagh, P, Vandesompele, J, Speleman, F, Jastrow, H, Heukamp, L C, Schüle, R, Dührsen, U, Buettner, R, Eggert, A, Göthert, J R

Volltext

Complete metabolic response in a patient with repeatedly relapsed non-small cell lung cancer harboring ROS1 gene rearrangement after treatment with crizotinib von Bos, M, Gardizi, M, Schildhaus, H.U, Heukamp, L.C, Geist, T, Kaminsky, B, Zander, T, Nogova, L, Scheffler, M, Dietlein, M, Kobe, C, Holstein, A, Maintz, D, Büttner, R, Wolf, J

Volltext

A Cre-conditional MYCN-driven neuroblastoma mouse model as an improved tool for preclinical studies von Althoff, K, Beckers, A, Bell, E, Nortmeyer, M, Thor, T, Sprüssel, A, Lindner, S, De Preter, K, Florin, A, Heukamp, L C, Klein-Hitpass, L, Astrahantseff, K, Kumps, C, Speleman, F, Eggert, A, Westermann, F, Schramm, A, Schulte, J H

Volltext

Insulin-like growth factor-1 receptor acts as a growth regulator in synovial sarcoma von Friedrichs, N, Küchler, J, Endl, E, Koch, A, Czerwitzki, J, Wurst, P, Metzger, D, Schulte, JH, Holst, MI, Heukamp, LC, Larsson, O, Tanaka, S, Kawai, A, Wardelmann, E, Buettner, R, Pietsch, T, Hartmann, W

Volltext

Insulin-like growth factor-I receptor acts as a growth regulator in synovial sarcoma von FRIEDRICHS, N, OCHLER, K, LARSSON, O, TANAKA, S, KAWAI, A, WARDELMANN, E, BUETTNER, R, PIETSCH, T, HARTMANN, W, ENDL, E, KOCH, A, CZERWITZKI, J, WURST, P, TIETZGER, D, SCHULTE, J. H, HOST, M. I, HEUKAMP, L. C

Volltext

Neurological course of long-term surviving patients with SCLC and anti-Hu syndrome von Poepel, A, Jarius, S, Heukamp, L.C, Urbach, H, Elger, C.E, Bien, C.G, Voltz, R

Volltext

Hybrid capture NGS reliably detects a spectrum of clinically significant genetic aberrations in both, primary diagnostics and the relapse scenario von Schatz, S., Falk, M., Menon, R., Heukamp, L.C., Roeper, J., Griesinger, F., Tiemann, M.

Volltext

Immune related endonucleases and GTPases are not associated with tumor response in patients with advanced non-small cell lung cancer treated with checkpoint inhibitors von Ramdani, H.O., Falk, M., Heukamp, L.C., Schatz, S., Tiemann, M., Wesseler, C., Diehl, L., Schuuring, E., Groen, H.J.M., Griesinger, F.

Volltext

Risk of not receiving second-line therapy is high in EGFR mt+ pts: Real world data of certified lung cancer centers on treatment sequence in EGFR mt+ pts von Roeper, J., Falk, M., Schatz, S., Tiemann, M., Wesseler, C., Wiest, G., Sackmann, S., Ukena, D., Heukamp, L.C., Griesinger, F.

Volltext

Effectiveness of crizotinib in a patient with ALK IHC-positive/FISH-negative metastatic lung adenocarcinoma von Rosoux, A, Pauwels, P, Duplaquet, F, D’Haene, N, Weynand, B, Delos, M, Menon, R, Heukamp, L.C, Thunnissen, E, Ocak, S

Volltext

ALK immunohistochemistry positive, FISH negative NSCLC is infrequent, but associated with impaired survival following treatment with crizotinib von Thunnissen, E., Lissenberg-Witte, B.I., van den Heuvel, M.M., Monkhorst, K., Skov, B.G., Sørensen, J.B., Mellemgaard, A., Dingemans, A.M.C., Speel, E.J.M., de Langen, A.J., Hashemi, S.M.S., Bahce, I., van der Drift, M.A., Looijen-Salamon, M.G., Gosney, J., Postmus, P.E., Samii, S.M.S., Duplaquet, F, Weynand, B., Durando, X., Penault-Llorca, F., Finn, S., Grady, A.O, Oz, B., Akyurek, N., Buettner, R., Wolf, J., Bubendorf, L., Duin, S., Marondel, I., Heukamp, L.C., Timens, W., Schuuring, E.M.D., Pauwels, P., Smit, E.F.

Volltext

TCam-2 but not JKT-1 cells resemble seminoma in cell culture von Eckert, D., Nettersheim, D., Heukamp, L. C., Kitazawa, S., Biermann, K., Schorle, H.

Volltext

Podocalyxin-like protein 1 expression in primary hepatic tumours and tumour-like lesions von Heukamp, L C, Fischer, H P, Schirmacher, P, Chen, X, Breuhahn, K, Nicolay, C, Büttner, R, Gütgemann, I

Volltext

Multi-Institutional Validation of the Predictive Value of Ki-67 Labeling Index in Patients With Urinary Bladder Cancer von Margulis, Vitaly, Lotan, Yair, Karakiewicz, Pierre I., Fradet, Yves, Ashfaq, Raheela, Capitanio, Umberto, Montorsi, Francesco, Bastian, Patrick J., Nielsen, Matthew E., Müller, Stefan C., Rigaud, Jérôme, Heukamp, Lukas C., Netto, George, Lerner, Seth P., Sagalowsky, Arthur I., Shariat, Shahrokh F.

Volltext

1432PHybrid capture NGS reliably detects a spectrum of clinically significant genetic aberrations in both, primary diagnostics and the relapse scenario von Schatz, S, Falk, M, Menon, R, Heukamp, L C, Roeper, J, Griesinger, F, Tiemann, M

Volltext

1489PDSecondary ROS1 mutations and lorlatinib sensitivity in crizotinib-refractory ROS1 positive NSCLC: Results of the prospective PFROST trial von Landi, L, Tiseo, M, Heukamp, L C, Menon, R, Spitaleri, G, Cortinovis, D L, Delmonte, A, Galetta, D, D’Arcangelo, M, D’Incà, F, Bertrand, M, Jóri, B, Zacher, A, Gridelli, C, Novello, S, Chiari, R, Verusio, C, Crinò, L, Cappuzzo, F

Volltext

1447PRisk of not receiving second-line therapy is high in EGFR mt+ pts: Real world data of certified lung cancer centers on treatment sequence in EGFR mt+ pts von Roeper, J, Falk, M, Schatz, S, Tiemann, M, Wesseler, C, Wiest, G, Sackmann, S, Ukena, D, Heukamp, L C, Griesinger, F

Volltext

Extraosseous osteosarcoma arising from the small intestinal mesentery von Heukamp, L.C., Knoblich, A., Rausch, E., Friedrichs, N., Schildhaus, H.U., Kahl, P., Tismer, R., Schneider, B., Büttner, R., Houshdaran, F.

Volltext

Cell-free Circulating DNA: Diagnostic Value in Patients with Renal Cell Cancer von HAUSER, Stefan, ZAHALKA, Tobias, ELLINGER, Jörg, FECHNER, Guido, HEUKAMP, Lukas C, VON RUECKER, Alexander, MÜLLER, Stefan C, BASTIAN, Patrick J

Volltext

P53 non-disruptive mutation is a negative predictive factor in EGFR M+ NSCLC treated with TKI von Griesinger, F., Netchaeva, M., Lüers, A., Prenzel, R., Scriba, D., Willborn, K.C., Stropiep, U., Hallas, C., Falk, M., Tiemann, M., Neemann, N., Heukamp, L.C., Roeper, J.

Volltext