DNA Origami Nanostructures Elicit Dose‐Dependent Immunogenicity and Are Nontoxic up to High Doses In Vivo von Lucas, Christopher R., Halley, Patrick D., Chowdury, Amjad A., Harrington, Bonnie K., Beaver, Larry, Lapalombella, Rosa, Johnson, Amy J., Hertlein, Erin K., Phelps, Mitch A., Byrd, John C., Castro, Carlos E.

Volltext

Bruton tyrosine kinase represents a promising therapeutic target for treatment of chronic lymphocytic leukemia and is effectively targeted by PCI-32765 von Herman, Sarah E.M., Gordon, Amber L., Hertlein, Erin, Ramanunni, Asha, Zhang, Xiaoli, Jaglowski, Samantha, Flynn, Joseph, Jones, Jeffrey, Blum, Kristie A., Buggy, Joseph J., Hamdy, Ahmed, Johnson, Amy J., Byrd, John C.

Volltext

TCL1 targeting miR-3676 is codeleted with tumor protein p53 in chronic lymphocytic leukemia von Balatti, Veronica, Rizzotto, Lara, Miller, Cecelia, Palamarchuk, Alexey, Fadda, Paolo, Pandolfo, Rosantony, Rassenti, Laura Z, Hertlein, Erin, Ruppert, Amy S, Lozanski, Arletta, Lozanski, Gerard, Kipps, Thomas J, Byrd, John C, Croce, Carlo M, Pekarsky, Yuri

Volltext

NF-κB Regulation of YY1 Inhibits Skeletal Myogenesis through Transcriptional Silencing of Myofibrillar Genes von Wang, Huating, Hertlein, Erin, Bakkar, Nadine, Sun, Hao, Acharyya, Swarnali, Wang, Jingxin, Carathers, Micheal, Davuluri, Ramana, Guttridge, Denis C.

Volltext

Significance of chromosome 2p gain in ibrutinib-treated chronic lymphocytic leukemia patients von Miller, Cecelia R., Huang, Ying, Ruppert, Amy S., Labanowska, Jadwiga, Jaglowski, Samantha M., Maddocks, Kami J., Rogers, Kerry A., Bhat, Seema, Kittai, Adam S., Grever, Michael, Lapalombella, Rosa, Abruzzo, Lynne V., Heerema, Nyla A., Byrd, John C., Hertlein, Erin K., Woyach, Jennifer A.

Volltext

Preclinical evaluation of the Hsp90 inhibitor SNX-5422 in ibrutinib resistant CLL von Chen, Timothy L., Harrington, Bonnie, Truxall, Jean, Wasmuth, Ronni, Prouty, Alexander, Sloan, Shelby, Lehman, Amy M., Sampath, Deepa, Orlemans, Eric, Baiocchi, Robert A., Alinari, Lapo, Byrd, John C., Woyach, Jennifer A., Hertlein, Erin

Volltext

Characterization of a new chronic lymphocytic leukemia cell line for mechanistic in vitro and in vivo studies relevant to disease von Hertlein, Erin, Beckwith, Kyle A, Lozanski, Gerard, Chen, Timothy L, Towns, William H, Johnson, Amy J, Lehman, Amy, Ruppert, Amy S, Bolon, Brad, Andritsos, Leslie, Lozanski, Arletta, Rassenti, Laura, Zhao, Weiqiang, Jarvinen, Tiina M, Senter, Leigha, Croce, Carlo M, Symer, David E, de la Chapelle, Albert, Heerema, Nyla A, Byrd, John C

Volltext

Preclinical efficacy for a novel tyrosine kinase inhibitor, ArQule 531 against acute myeloid leukemia von Elgamal, Ola A., Mehmood, Abeera, Jeon, Jae Yoon, Carmichael, Bridget, Lehman, Amy, Orwick, Shelley J., Truxall, Jean, Goettl, Virginia M., Wasmuth, Ronni, Tran, Minh, Mitchell, Shaneice, Lapalombella, Rosa, Eathiraj, Sudharshan, Schwartz, Brian, Stegmaier, Kimberly, Baker, Sharyn D., Hertlein, Erin, Byrd, John C.

Volltext

The long noncoding RNA, treRNA, decreases DNA damage and is associated with poor response to chemotherapy in chronic lymphocytic leukemia von Miller, Cecelia R, Ruppert, Amy S, Fobare, Sydney, Chen, Timothy L, Liu, Chaomei, Lehman, Amy, Blachly, James S, Zhang, Xiaoli, Lucas, David M, Grever, Michael R, Tallman, Martin S, Flinn, Ian W, Rassenti, Laura Z, Kipps, Thomas J, Sampath, Deepa, Coombes, Kevin R, Hertlein, Erin K

Volltext

Mass Cytometry as a Tool for Investigating Senescence in Multiple Model Systems von Abdul-Aziz, Amina, Devine, Raymond D, Lyberger, Justin M, Chang, Hsiaochi, Kovacs, Amy, Lerma, James R, Rogers, Andrew M, Byrd, John C, Hertlein, Erin, Behbehani, Gregory K

Volltext

Framework of clonal mutations concurrent with WT1 mutations in adults with acute myeloid leukemia: Alliance for Clinical Trials in Oncology study von Bhatnagar, Bhavana, Kohlschmidt, Jessica, Orwick, Shelley J., Buelow, Daelynn R., Fobare, Sydney, Oakes, Christopher C., Kolitz, Jonathan E., Uy, Geoff, Stock, Wendy, Powell, Bayard L., Nicolet, Deedra, Hertlein, Erin K., Mrózek, Krzysztof, Blachly, James S., Eisfeld, Ann-Kathrin, Baker, Sharyn D., Byrd, John C.

Volltext

Near-tetraploidy is associated with Richter transformation in chronic lymphocytic leukemia patients receiving ibrutinib von Miller, Cecelia R., Ruppert, Amy S., Heerema, Nyla A., Maddocks, Kami J., Labanowska, Jadwiga, Breidenbach, Heather, Lozanski, Gerard, Zhao, Weiqiang, Gordon, Amber L., Jones, Jeffrey A., Flynn, Joseph M., Jaglowski, Samantha M., Andritsos, Leslie A., Blum, Kristie A., T. Awan, Farrukh, Rogers, Kerry A., Grever, Michael R., Johnson, Amy J., Abruzzo, Lynne V., Hertlein, Erin K., Blachly, James S., Woyach, Jennifer A., Byrd, John C.

Volltext

Epigenetic changes during disease progression in a murine model of human chronic lymphocytic leukemia von Chen, Shih-Shih, Raval, Aparna, Johnson, Amy J, Hertlein, Erin, Liu, Te-Hui, Jin, Victor X, Sherman, Mara H, Liu, Shu-Jun, Dawson, David W, Williams, Katie E, Lanasa, Mark, Liyanarachchi, Sandya, Lin, Thomas S, Marcucci, Guido, Pekarsky, Yuri, Davuluri, Ramana, Croce, Carlo M, Guttridge, Denis C, Teitell, Michael A, Byrd, John C, Plass, Christoph

Volltext

A FOXy target in B-cell survival von Hertlein, Erin

Volltext

TP-0903 is active in models of drug-resistant acute myeloid leukemia von Jeon, Jae Yoon, Buelow, Daelynn R., Garrison, Dominique A., Niu, Mingshan, Eisenmann, Eric D., Huang, Kevin M., Thomas, Megan E. Zavorka, Weber, Robert H., Whatcott, Clifford J., Warner, Steve L., Orwick, Shelley J., Carmichael, Bridget, Stahl, Emily, Brinton, Lindsey T., Lapalombella, Rosa, Blachly, James S., Hertlein, Erin, Byrd, John C., Bhatnagar, Bhavana, Baker, Sharyn D.

Volltext

Milatuzumab immunoliposomes induce cell death in CLL by promoting accumulation of CD74 on the surface of B cells von Hertlein, Erin, Triantafillou, Georgia, Sass, Ellen J., Hessler, Joshua D., Zhang, Xiaoli, Jarjoura, David, Lucas, David M., Muthusamy, Natarajan, Goldenberg, David M., Lee, Robert J., Byrd, John C.

Volltext

Hsp90 inhibition increases SOCS3 transcript and regulates migration and cell death in chronic lymphocytic leukemia von Chen, Timothy L, Gupta, Nikhil, Lehman, Amy, Ruppert, Amy S, Yu, Lianbo, Oakes, Christopher C, Claus, Rainer, Plass, Christoph, Maddocks, Kami J, Andritsos, Leslie, Jones, Jeffery A, Lucas, David M, Johnson, Amy J, Byrd, John C, Hertlein, Erin

Volltext

Signalling to drug resistance in CLL von Hertlein, Erin, PhD, Byrd, John C., MD

Volltext

Age and Sex Differences in the Eμ-TCL1 Adoptive Transfer Mouse Model of CLL von Sharpe, Chia, Perry, Elizabeth, Hertlein, Erin, Muthusamy, Natarajan, Byrd, John C.

Volltext

Epigenetic alterations in a murine model for chronic lymphocytic leukemia von Chen, Shih-Shih, Sherman, Mara H., Hertlein, Erin, Johnson, Amy J., Teitell, Michael A., Byrd, John C., Plass, Christoph

Volltext