Ultrasensitive quantification of HIV-1 cell-to-cell transmission in primary human CD4 + T cells measures viral sensitivity to broadly neutralizing antibodies von Mazurov, Dmitriy, Herschhorn, Alon

Volltext

The β20–β21 of gp120 is a regulatory switch for HIV-1 Env conformational transitions von Herschhorn, Alon, Gu, Christopher, Moraca, Francesca, Ma, Xiaochu, Farrell, Mark, Smith, Amos B., Pancera, Marie, Kwong, Peter D., Schön, Arne, Freire, Ernesto, Abrams, Cameron, Blanchard, Scott C., Mothes, Walther, Sodroski, Joseph G.

Volltext

Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry von Lai, Yen-Ting, Wang, Tao, O’Dell, Sijy, Louder, Mark K., Schön, Arne, Cheung, Crystal S. F., Chuang, Gwo-Yu, Druz, Aliaksandr, Lin, Bob, McKee, Krisha, Peng, Dongjun, Yang, Yongping, Zhang, Baoshan, Herschhorn, Alon, Sodroski, Joseph, Bailer, Robert T., Doria-Rose, Nicole A., Mascola, John R., Langley, David R., Kwong, Peter D.

Volltext

A broad HIV-1 inhibitor blocks envelope glycoprotein transitions critical for entry von Herschhorn, Alon, Gu, Christopher, Espy, Nicole, Richard, Jonathan, Finzi, Andrés, Sodroski, Joseph G

Volltext

Conformational flexibility of HIV-1 envelope glycoproteins modulates transmitted/founder sensitivity to broadly neutralizing antibodies von Parthasarathy, Durgadevi, Pothula, Karunakar Reddy, Ratnapriya, Sneha, Cervera Benet, Héctor, Parsons, Ruth, Huang, Xiao, Sammour, Salam, Janowska, Katarzyna, Harris, Miranda, Sodroski, Joseph, Acharya, Priyamvada, Herschhorn, Alon

Volltext

Comparative Analysis of the Glycosylation Profiles of Membrane-Anchored HIV-1 Envelope Glycoprotein Trimers and Soluble gp140 von Go, Eden P, Herschhorn, Alon, Gu, Christopher, Castillo-Menendez, Luis, Zhang, Shijian, Mao, Youdong, Chen, Haiyan, Ding, Haitao, Wakefield, John K, Hua, David, Liao, Hua-Xin, Kappes, John C, Sodroski, Joseph, Desaire, Heather

Volltext

Alternative substitutions of N332 in HIV-1AD8 gp120 differentially affect envelope glycoprotein function and viral sensitivity to broadly neutralizing antibodies targeting the V3-g... von Jeffy, Jeffy, Parthasarathy, Durgadevi, Ahmed, Shamim, Cervera-Benet, Héctor, Xiong, Ulahn, Harris, Miranda, Mazurov, Dmitriy, Pickthorn, Stephanie, Herschhorn, Alon

Volltext

Release of gp120 Restraints Leads to an Entry-Competent Intermediate State of the HIV-1 Envelope Glycoproteins von Herschhorn, Alon, Ma, Xiaochu, Gu, Christopher, Ventura, John D, Castillo-Menendez, Luis, Melillo, Bruno, Terry, Daniel S, Smith, 3rd, Amos B, Blanchard, Scott C, Munro, James B, Mothes, Walther, Finzi, Andrés, Sodroski, Joseph

Volltext

Molecular architecture of the uncleaved HIV-1 envelope glycoprotein trimer von Mao, Youdong, Wang, Liping, Gu, Christopher, Herschhorn, Alon, Désormeaux, Anik, Finzi, Andrés, Xiang, Shi-Hua, Sodroski, Joseph G.

Volltext

Activation and Inactivation of Primary Human Immunodeficiency Virus Envelope Glycoprotein Trimers by CD4-Mimetic Compounds von Madani, Navid, Princiotto, Amy M, Zhao, Connie, Jahanbakhshsefidi, Fatemeh, Mertens, Max, Herschhorn, Alon, Melillo, Bruno, Smith, 3rd, Amos B, Sodroski, Joseph

Volltext

A Protocol for Studying HIV-1 Envelope Glycoprotein Function von Ratnapriya, Sneha, Chov, Angela, Herschhorn, Alon

Volltext

Residues in the gp41 Ectodomain Regulate HIV-1 Envelope Glycoprotein Conformational Transitions Induced by gp120-Directed Inhibitors von Pacheco, Beatriz, Alsahafi, Nirmin, Debbeche, Olfa, Prévost, Jérémie, Ding, Shilei, Chapleau, Jean-Philippe, Herschhorn, Alon, Madani, Navid, Princiotto, Amy, Melillo, Bruno, Gu, Christopher, Zeng, Xin, Mao, Youdong, Smith, 3rd, Amos B, Sodroski, Joseph, Finzi, Andrés

Volltext

CPSF6-Dependent Targeting of Speckle-Associated Domains Distinguishes Primate from Nonprimate Lentiviral Integration von Li, Wen, Singh, Parmit K, Sowd, Gregory A, Bedwell, Gregory J, Jang, Sooin, Achuthan, Vasudevan, Oleru, Amarachi V, Wong, Doris, Fadel, Hind J, Lee, KyeongEun, KewalRamani, Vineet N, Poeschla, Eric M, Herschhorn, Alon, Engelman, Alan N

Volltext

Insights from HIV-1 vaccine and passive immunization efficacy trials von Ahmed, Shamim, Herschhorn, Alon

Volltext

Indirect Mechanisms of HIV‑1 Evasion from Broadly Neutralizing Antibodies In Vivo von Herschhorn, Alon

Volltext

SERINC5 Restricts HIV-1 Infectivity by Promoting Conformational Changes and Accelerating Functional Inactivation of Env von Kirschman, Junghwa, Marin, Mariana, Chen, Yen-Cheng, Chen, Junhua, Herschhorn, Alon, Smith, 3rd, Amos B, Melikyan, Gregory B

Volltext

A protocol for displaying viral envelope glycoproteins on the surface of vesicular stomatitis viruses von Farzani, Touraj Aligholipour, Chov, Angela, Herschhorn, Alon

Volltext

Conformation of HIV-1 Envelope Governs Rhesus CD4 Usage and Simian-Human Immunodeficiency Virus Replication von Vilmen, Geraldine, Smith, Anna C, Benet, Hector Cervera, Shukla, Rajni Kant, Larue, Ross C, Herschhorn, Alon, Sharma, Amit

Volltext

The Highly Conserved Layer-3 Component of the HIV-1 gp120 Inner Domain Is Critical for CD4-Required Conformational Transitions von Désormeaux, Anik, Coutu, Mathieu, Medjahed, Halima, Pacheco, Beatriz, Herschhorn, Alon, Gu, Christopher, Xiang, Shi-Hua, Mao, Youdong, Sodroski, Joseph, Finzi, Andrés

Volltext

Loss of a conserved N-linked glycosylation site in the simian immunodeficiency virus envelope glycoprotein V2 region enhances macrophage tropism by increasing CD4-independent cell-... von Yen, Po-Jen, Herschhorn, Alon, Haim, Hillel, Salas, Ignacio, Gu, Christopher, Sodroski, Joseph, Gabuzda, Dana

Volltext