Pancreatic cancer stem cells: A state or an entity? von Hermann, Patrick C., Sainz, Bruno

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Pancreatic stellate cells form a niche for cancer stem cells and promote their self-renewal and invasiveness von Lonardo, Enza, Frias-Aldeguer, Javier, Hermann, Patrick C., Heeschen, Christopher

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ISG15 and ISGylation is required for pancreatic cancer stem cell mitophagy and metabolic plasticity von Alcalá, Sonia, Sancho, Patricia, Martinelli, Paola, Navarro, Diego, Pedrero, Coral, Martín-Hijano, Laura, Valle, Sandra, Earl, Julie, Rodríguez-Serrano, Macarena, Ruiz-Cañas, Laura, Rojas, Katerin, Carrato, Alfredo, García-Bermejo, Laura, Fernández-Moreno, Miguel Ángel, Hermann, Patrick C., Sainz, Bruno

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EMT and Stemness-Key Players in Pancreatic Cancer Stem Cells von Rodriguez-Aznar, Eva, Wiesmüller, Lisa, Sainz, Jr, Bruno, Hermann, Patrick C

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Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer von Hermann, Patrick C, Huber, Stephan L, Herrler, Tanja, Aicher, Alexandra, Ellwart, Joachim W, Guba, Markus, Bruns, Christiane J, Heeschen, Christopher

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Exploiting oxidative phosphorylation to promote the stem and immunoevasive properties of pancreatic cancer stem cells von Valle, Sandra, Alcalá, Sonia, Martin-Hijano, Laura, Cabezas-Sáinz, Pablo, Navarro, Diego, Muñoz, Edurne Ramos, Yuste, Lourdes, Tiwary, Kanishka, Walter, Karolin, Ruiz-Cañas, Laura, Alonso-Nocelo, Marta, Rubiolo, Juan A., González-Arnay, Emilio, Heeschen, Christopher, Garcia-Bermejo, Laura, Hermann, Patrick C., Sánchez, Laura, Sancho, Patricia, Fernández-Moreno, Miguel Ángel, Sainz, Bruno

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Modeling plasticity and dysplasia of pancreatic ductal organoids derived from human pluripotent stem cells von Breunig, Markus, Merkle, Jessica, Wagner, Martin, Melzer, Michael K., Barth, Thomas F.E., Engleitner, Thomas, Krumm, Johannes, Wiedenmann, Sandra, Cohrs, Christian M., Perkhofer, Lukas, Jain, Gaurav, Krüger, Jana, Hermann, Patrick C., Schmid, Maximilian, Madácsy, Tamara, Varga, Árpád, Griger, Joscha, Azoitei, Ninel, Müller, Martin, Wessely, Oliver, Robey, Pamela G., Heller, Sandra, Dantes, Zahra, Reichert, Maximilian, Günes, Cagatay, Bolenz, Christian, Kuhn, Florian, Maléth, József, Speier, Stephan, Liebau, Stefan, Sipos, Bence, Kuster, Bernhard, Seufferlein, Thomas, Rad, Roland, Meier, Matthias, Hohwieler, Meike, Kleger, Alexander

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Nodal/Activin Signaling Drives Self-Renewal and Tumorigenicity of Pancreatic Cancer Stem Cells and Provides a Target for Combined Drug Therapy von Lonardo, Enza, Hermann, Patrick C., Mueller, Maria-Theresa, Huber, Stephan, Balic, Anamaria, Miranda-Lorenzo, Irene, Zagorac, Sladjana, Alcala, Sonia, Rodriguez-Arabaolaza, Iker, Ramirez, Juan Carlos, Torres-Ruíz, Raul, Garcia, Elena, Hidalgo, Manuel, Cebrián, David Álvaro, Heuchel, Rainer, Löhr, Matthias, Berger, Frank, Bartenstein, Peter, Aicher, Alexandra, Heeschen, Christopher

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Macrophages direct cancer cells through a LOXL2-mediated metastatic cascade in pancreatic ductal adenocarcinoma von Alonso-Nocelo, Marta, Ruiz-Cañas, Laura, Sancho, Patricia, Görgülü, Kıvanç, Alcalá, Sonia, Pedrero, Coral, Vallespinos, Mireia, López-Gil, Juan Carlos, Ochando, Marina, García-García, Elena, David Trabulo, Sara Maria, Martinelli, Paola, Sánchez-Tomero, Patricia, Sánchez-Palomo, Carmen, Gonzalez-Santamaría, Patricia, Yuste, Lourdes, Wörmann, Sonja Maria, Kabacaoğlu, Derya, Earl, Julie, Martin, Alberto, Salvador, Fernando, Valle, Sandra, Martin-Hijano, Laura, Carrato, Alfredo, Erkan, Mert, García-Bermejo, Laura, Hermann, Patrick C, Algül, Hana, Moreno-Bueno, Gema, Heeschen, Christopher, Portillo, Francisco, Cano, Amparo, Sainz, Bruno

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Synergistic targeting and resistance to PARP inhibition in DNA damage repair-deficient pancreatic cancer von Gout, Johann, Perkhofer, Lukas, Morawe, Mareen, Arnold, Frank, Ihle, Michaela, Biber, Stephanie, Lange, Sebastian, Roger, Elodie, Kraus, Johann M, Stifter, Katja, Hahn, Stephan A, Zamperone, Andrea, Engleitner, Thomas, Müller, Martin, Walter, Karolin, Rodriguez-Aznar, Eva, Sainz Jr, Bruno, Hermann, Patrick C, Hessmann, Elisabeth, Müller, Sebastian, Azoitei, Ninel, Lechel, André, Liebau, Stefan, Wagner, Martin, Simeone, Diane M, Kestler, Hans A, Seufferlein, Thomas, Wiesmüller, Lisa, Rad, Roland, Frappart, Pierre-Olivier, Kleger, Alexander

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Nicotine Promotes Initiation and Progression of KRAS-Induced Pancreatic Cancer via Gata6- Dependent Dedifferentiation of Acinar Cells in Mice von Hermann, Patrick C, Sancho, Patricia, Cañamero, Marta, Martinelli, Paola, Madriles, Francesc, Michl, Patrick, Gress, Thomas, de Pascual, Ricardo, Gandia, Luis, Guerra, Carmen, Barbacid, Mariano, Wagner, Martin, Vieira, Catarina R, Aicher, Alexandra, Real, Francisco X, Sainz, Bruno, Heeschen, Christopher

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IgG4-Related Diseases in the Gastrointestinal Tract: Clinical Presentation, Diagnosis and Treatment Challenges von Backhus, Johanna, Seufferlein, Thomas, Perkhofer, Lukas, Hermann, Patrick C., Kleger, Alexander

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Combined Targeted Treatment to Eliminate Tumorigenic Cancer Stem Cells in Human Pancreatic Cancer von Mueller, Maria–Theresa, Hermann, Patrick C, Witthauer, Juliane, Rubio–Viqueira, Belen, Leicht, Simon F, Huber, Stephan, Ellwart, Joachim W, Mustafa, Mona, Bartenstein, Peter, D'Haese, Jan G, Schoenberg, Michael H, Berger, Frank, Jauch, Karl–Walter, Hidalgo, Manuel, Heeschen, Christopher

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The role of pluripotency factors to drive stemness in gastrointestinal cancer von Müller, Martin, Hermann, Patrick C., Liebau, Stefan, Weidgang, Clair, Seufferlein, Thomas, Kleger, Alexander, Perkhofer, Lukas

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Vascular Incorporation of Endothelial Colony-Forming Cells Is Essential for Functional Recovery of Murine Ischemic Tissue Following Cell Therapy von Schwarz, Theresa M, Leicht, Simon F, Radic, Tamara, Rodriguez-Araboalaza, Iker, Hermann, Patrick C, Berger, Frank, Saif, Jaimy, Böcker, Wolfgang, Ellwart, Joachim W, Aicher, Alexandra, Heeschen, Christopher

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Pancreatic cancer stem cells – update and future perspectives von Lonardo, Enza, Hermann, Patrick C., Heeschen, Christopher

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Reprogramming tumor-associated macrophages with lipid nanosystems reduces PDAC tumor burden and liver metastasis von Palencia-Campos, Adrián, Ruiz-Cañas, Laura, Abal-Sanisidro, Marcelina, López-Gil, Juan Carlos, Batres-Ramos, Sandra, Saraiva, Sofia Mendes, Yagüe, Balbino, Navarro, Diego, Alcalá, Sonia, Rubiolo, Juan A, Bidan, Nadège, Sánchez, Laura, Mura, Simona, Hermann, Patrick C, de la Fuente, María, Sainz, Bruno

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Pancreatic cancer-derived organoids – a disease modeling tool to predict drug response von Frappart, Pierre-Olivier, Walter, Karolin, Gout, Johann, Beutel, Alica K, Morawe, Mareen, Arnold, Frank, Breunig, Markus, Barth, Thomas FE, Marienfeld, Ralf, Schulte, Lucas, Ettrich, Thomas, Hackert, Thilo, Svinarenko, Michael, Rösler, Reinhild, Wiese, Sebastian, Wiese, Heike, Perkhofer, Lukas, Müller, Martin, Lechel, André, Sainz, Bruno, Hermann, Patrick C, Seufferlein, Thomas, Kleger, Alexander

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Multimodal Treatment Eliminates Cancer Stem Cells and Leads to Long-Term Survival in Primary Human Pancreatic Cancer Tissue Xenografts von Hermann, Patrick C, Trabulo, Sara M, Sainz, Jr, Bruno, Balic, Anamaria, Garcia, Elena, Hahn, Stephan A, Vandana, Mallaredy, Sahoo, Sanjeeb K, Tunici, Patrizia, Bakker, Annette, Hidalgo, Manuel, Heeschen, Christopher

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The Anthrax Toxin Receptor 1 (ANTXR1) Is Enriched in Pancreatic Cancer Stem Cells Derived from Primary Tumor Cultures von Heeschen, Christopher, Hermann, Patrick C., Martinelli, Paola, Alcalá, Sonia, Sainz, Bruno

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