Identification of Small Inhibitory Molecules Targeting the Bfl-1 Anti-Apoptotic Protein That Alleviates Resistance to ABT-737 von Mathieu, Anne-Laure, Sperandio, Olivier, Pottiez, Virginie, Balzarin, Sophie, Herlédan, Adrien, Elkaïm, Judith O., Fogeron, Marie-Laure, Piveteau, Catherine, Dassonneville, Sandrine, Deprez, Benoit, Villoutreix, Bruno O., Bonnefoy, Nathalie, Leroux, Florence

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Pyridylpiperazine-based allosteric inhibitors of RND-type multidrug efflux pumps von Plé, Coline, Tam, Heng-Keat, Vieira Da Cruz, Anais, Compagne, Nina, Jiménez-Castellanos, Juan-Carlos, Müller, Reinke T., Pradel, Elizabeth, Foong, Wuen Ee, Malloci, Giuliano, Ballée, Alexia, Kirchner, Moritz A., Moshfegh, Parisa, Herledan, Adrien, Herrmann, Andrea, Deprez, Benoit, Willand, Nicolas, Vargiu, Attilio Vittorio, Pos, Klaas M., Flipo, Marion, Hartkoorn, Ruben C.

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Controlling Plasma Stability of Hydroxamic Acids: A MedChem Toolbox von Hermant, Paul, Bosc, Damien, Piveteau, Catherine, Gealageas, Ronan, Lam, BaoVy, Ronco, Cyril, Roignant, Matthieu, Tolojanahary, Hasina, Jean, Ludovic, Renard, Pierre-Yves, Lemdani, Mohamed, Bourotte, Marilyne, Herledan, Adrien, Bedart, Corentin, Biela, Alexandre, Leroux, Florence, Deprez, Benoit, Deprez-Poulain, Rebecca

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Rubrolone production by Dactylosporangium vinaceum: biosynthesis, modulation and possible biological function von Moureu, Sophie, Caradec, Thibault, Trivelli, Xavier, Drobecq, Hervé, Beury, Delphine, Bouquet, Peggy, Caboche, Segolene, Desmecht, Eva, Maurier, Florence, Muharram, Ghaffar, Villemagne, Baptiste, Herledan, Adrien, Hot, David, Willand, Nicolas, Hartkoorn, Ruben Christiaan

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High-Throughput Quantitative Screening of Glucose-Stimulated Insulin Secretion and Insulin Content Using Automated MALDI-TOF Mass Spectrometry von Delannoy, Clément Philippe, Heuson, Egon, Herledan, Adrien, Oger, Frederik, Thiroux, Bryan, Chevalier, Mickaël, Gromada, Xavier, Rolland, Laure, Froguel, Philippe, Deprez, Benoit, Paul, Sébastien, Annicotte, Jean-Sébastien

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Structure–activity relationships of imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, dual binders of human insulin-degrading enzyme von Charton, Julie, Gauriot, Marion, Totobenazara, Jane, Hennuyer, Nathalie, Dumont, Julie, Bosc, Damien, Marechal, Xavier, Elbakali, Jamal, Herledan, Adrien, Wen, Xiaoan, Ronco, Cyril, Gras-Masse, Helene, Heninot, Antoine, Pottiez, Virginie, Landry, Valerie, Staels, Bart, Liang, Wenguang G., Leroux, Florence, Tang, Wei-Jen, Deprez, Benoit, Deprez-Poulain, Rebecca

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Receptor-Interacting Protein 140 Differentially Regulates Estrogen Receptor-Related Receptor Transactivation Depending on Target Genes von Castet, Audrey, Herledan, Adrien, Bonnet, Sandrine, Jalaguier, Stéphan, Vanacker, Jean-Marc, Cavaillès, Vincent

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Small molecule MarR modulators potentiate metronidazole antibiotic activity in aerobic E. coli by inducing activation by the nitroreductase NfsA von Caradec, Thibault, Plé, Coline, Sicoli, Giuseppe, Petrov, Ravil, Pradel, Elizabeth, Sobieski, Cécilia, Antoine, Rudy, Orio, Maylis, Herledan, Adrien, Willand, Nicolas, Hartkoorn, Ruben Christiaan

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Insulin-degrading enzyme inhibition increases the unfolded protein response and favours lipid accumulation in the liver von Andres, Marine, Hennuyer, Nathalie, Zibar, Khamis, Bicharel-Leconte, Marie, Duplan, Isabelle, Enée, Emmanuelle, Vallez, Emmanuelle, Herledan, Adrien, Loyens, Anne, Staels, Bart, Déprez, Benoît, van Endert, Peter, Deprez-Poulain, Rebecca, Lancel, Steve S.

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Insulin‐degrading enzyme inhibition increases the unfolded protein response and favours lipid accumulation in the liver von Andres, Marine, Hennuyer, Nathalie, Zibar, Khamis, Bicharel‐Leconte, Marie, Duplan, Isabelle, Enée, Emmanuelle, Vallez, Emmanuelle, Herledan, Adrien, Loyens, Anne, Staels, Bart, Deprez, Benoit, Endert, Peter, Deprez‐Poulain, Rebecca, Lancel, Steve

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BIN1 recovers tauopathy-induced long-term memory deficits in mice and interacts with Tau through Thr.sup.348 phosphorylation von Sartori, Maxime, Mendes, Tiago, Desai, Shruti, Lasorsa, Alessia, Herledan, Adrien, Malmanche, Nicolas, Mäkinen, Petra

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Tricyclic SpiroLactams Kill Mycobacteria In Vitro and In Vivo by Inhibiting Type II NADH Dehydrogenases von Dam, Sushovan, Tangara, Salia, Hamela, Claire, Hattabi, Theo, Faïon, Léo, Carre, Paul, Antoine, Rudy, Herledan, Adrien, Leroux, Florence, Piveteau, Catherine, Eveque, Maxime, Flipo, Marion, Deprez, Benoit, Kremer, Laurent, Willand, Nicolas, Villemagne, Baptiste, Hartkoorn, Ruben C.

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Novel dithiocarbamates selectively inhibit 3CL protease of SARS-CoV-2 and other coronaviruses von Brier, Lucile, Hassan, Haitham, Hanoulle, Xavier, Landry, Valerie, Moschidi, Danai, Desmarets, Lowiese, Rouillé, Yves, Dumont, Julie, Herledan, Adrien, Warenghem, Sandrine, Piveteau, Catherine, Carré, Paul, Ikherbane, Sarah, Cantrelle, François-Xavier, Dupré, Elian, Dubuisson, Jean, Belouzard, Sandrine, Leroux, Florence, Deprez, Benoit, Charton, Julie

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Topical Intestinal Aminoimidazole Agonists of G‑Protein-Coupled Bile Acid Receptor 1 Promote Glucagon Like Peptide‑1 Secretion and Improve Glucose Tolerance von Lasalle, Manuel, Hoguet, Vanessa, Hennuyer, Nathalie, Leroux, Florence, Piveteau, Catherine, Belloy, Loïc, Lestavel, Sophie, Vallez, Emmanuelle, Dorchies, Emilie, Duplan, Isabelle, Sevin, Emmanuel, Culot, Maxime, Gosselet, Fabien, Boulahjar, Rajaa, Herledan, Adrien, Staels, Bart, Deprez, Benoit, Tailleux, Anne, Charton, Julie

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N-acylbenzimidazoles as selective Acylators of the catalytic cystein of the coronavirus 3CL protease von Chaibi, Fatima-Zahra, Brier, Lucile, Carré, Paul, Landry, Valérie, Desmarets, Lowiese, Tarricone, Audrey, Cantrelle, François-Xavier, Moschidi, Danai, Herledan, Adrien, Biela, Alexandre, Bourgeois, Fanny, Ribes, Chloé, Ikherbane, Sarah, Malessan, Mathilde, Dubuisson, Jean, Belouzard, Sandrine, Hanoulle, Xavier, Leroux, Florence, Deprez, Benoit, Charton, Julie

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Identification of indole-based activators of insulin degrading enzyme von Kraupner, Nicolas, Dinh, Chau Phi, Wen, Xiaoan, Landry, Valérie, Herledan, Adrien, Leroux, Florence, Bosc, Damien, Charton, Julie, Maillard, Clara, Warenghem, Sandrine, Duplan, Isabelle, Piveteau, Catherine, Hennuyer, Nathalie, Staels, Bart, Deprez, Benoit, Deprez-Poulain, Rebecca

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Discovery of the First Selective Nanomolar Inhibitors of ERAP2 by Kinetic Target‐Guided Synthesis von Camberlein, Virgyl, Fléau, Charlotte, Sierocki, Pierre, Li, Lenong, Gealageas, Ronan, Bosc, Damien, Guillaume, Valentin, Warenghem, Sandrine, Leroux, Florence, Rosell, Melissa, Cheng, Keguang, Medve, Laura, Prigent, Mathilde, Decanter, Myriam, Piveteau, Catherine, Biela, Alexandre, Eveque, Maxime, Dumont, Julie, Mpakali, Anastasia, Giastas, Petros, Herledan, Adrien, Couturier, Cyril, Haupenthal, Jörg, Lesire, Laetitia, Hirsch, Anna K. H., Deprez, Benoit, Stratikos, Efstratios, Bouvier, Marlene, Deprez‐Poulain, Rebecca

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Beyond the Rule of 5: Impact of PEGylation with Various Polymer Sizes on Pharmacokinetic Properties, Structure–Properties Relationships of mPEGylated Small Agonists of TGR5 Recepto... von Hoguet, Vanessa, Lasalle, Manuel, Maingot, Mathieu, Dequirez, Geoffroy, Boulahjar, Rajaa, Leroux, Florence, Piveteau, Catherine, Herledan, Adrien, Biela, Alexandre, Dumont, Julie, Chávez-Talavera, Oscar, Belloy, Loïc, Duplan, Isabelle, Hennuyer, Nathalie, Butruille, Laura, Lestavel, Sophie, Sevin, Emmanuel, Culot, Maxime, Gosselet, Fabien, Staels, Bart, Deprez, Benoit, Tailleux, Anne, Charton, Julie

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Identification of ebselen as a potent inhibitor of insulin degrading enzyme by a drug repurposing screening von Leroux, Florence, Bosc, Damien, Beghyn, Terence, Hermant, Paul, Warenghem, Sandrine, Landry, Valérie, Pottiez, Virginie, Guillaume, Valentin, Charton, Julie, Herledan, Adrien, Urata, Sarah, Liang, Wenguang, Sheng, Li, Tang, Wei-Jen, Deprez, Benoit, Deprez-Poulain, Rebecca

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Discovery of the First Selective Nanomolar Inhibitors of Endoplasmic Reticulum Aminopeptidase 2 by Kinetic Target‐Guided Synthesis von Camberlein, Virgyl, Fleau-Tabey, Charlotte, Sierocki, Pierre, Li, Lenong, Gealageas, Ronan, Bosc, Damien, Guillaume, Valentin, Warenghem, Sandrine, Leroux, Florence, Rosell, Melissa, Cheng, Keguang, Medve, Laura, Prigent, Mathilde, Decanter, Myriam, Piveteau, Catherine, Biela, Alexandre, Eveque, Maxime, Dumont, Julie, Mpakali, Anastasia, Giastas, Petros, Herledan, Adrien, Couturier, Cyril, Haupenthal, Jörg, Lesire, Laetitia, Hirsch, Anna, Deprez, Benoit, Stratikos, Efstratios, Bouvier, Marlene, Deprez-Poulain, Rebecca

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