Optimizing sgRNA length to improve target specificity and efficiency for the GGTA1 gene using the CRISPR/Cas9 gene editing system von Matson, Anders W, Hosny, Nora, Swanson, Zachary A, Hering, Bernhard J, Burlak, Christopher

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High-mannose type N-glycans with core fucosylation and complex-type N-glycans with terminal neuraminic acid residues are unique to porcine islets von Nanno, Yoshihide, Shajahan, Asif, Sonon, Roberto N., Azadi, Parastoo, Hering, Bernhard J., Burlak, Christopher

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Evidence-informed clinical practice recommendations for treatment of type 1 diabetes complicated by problematic hypoglycemia von Choudhary, Pratik, Rickels, Michael R, Senior, Peter A, Vantyghem, Marie-Christine, Maffi, Paola, Kay, Thomas W, Keymeulen, Bart, Inagaki, Nobuya, Saudek, Frantisek, Lehmann, Roger, Hering, Bernhard J

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Factors Predicting Outcomes After a Total Pancreatectomy and Islet Autotransplantation Lessons Learned From Over 500 Cases von Chinnakotla, Srinath, Beilman, Gregory J, Dunn, Ty B, Bellin, Melena D, Freeman, Martin L, Radosevich, David M, Arain, Mustafa, Amateau, Stuart K, Mallery, J Shawn, Schwarzenberg, Sarah J, Clavel, Alfred, Wilhelm, Joshua, Robertson, R Paul, Berry, Louise, Cook, Marie, Hering, Bernhard J, Sutherland, David E.R, Pruett, Timothy L

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2008 Update From the Collaborative Islet Transplant Registry von ALEJANDRO, Rodolfo, BARTON, Franca B, HERING, Bernhard J, WEASE, Steve

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Long-term tolerance of islet allografts in nonhuman primates induced by apoptotic donor leukocytes von Singh, Amar, Ramachandran, Sabarinathan, Graham, Melanie L., Daneshmandi, Saeed, Heller, David, Suarez-Pinzon, Wilma Lucia, Balamurugan, Appakalai N., Ansite, Jeffrey D., Wilhelm, Joshua J., Yang, Amy, Zhang, Ying, Palani, Nagendra P., Abrahante, Juan E., Burlak, Christopher, Miller, Stephen D., Luo, Xunrong, Hering, Bernhard J.

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Carbohydrate antigen microarray analysis of serum IgG and IgM antibodies before and after adult porcine islet xenotransplantation in cynomolgus macaques von Nanno, Yoshihide, Sterner, Eric, Gildersleeve, Jeffrey C., Hering, Bernhard J., Burlak, Christopher

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Regulation of Clinical Xenotransplantation—Time for a Reappraisal von Cooper, David K.C, Pierson, Richard N, Hering, Bernhard J, Mohiuddin, Muhammad M, Fishman, Jay A, Denner, Joachim, Ahn, Curie, Azimzadeh, Agnes M, Buhler, Leo H, Cowan, Peter J, Hawthorne, Wayne J, Kobayashi, Takaaki, Sachs, David H

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Clinically available immunosuppression averts rejection but not systemic inflammation after porcine islet xenotransplant in cynomolgus macaques von Graham, Melanie L., Ramachandran, Sabarinathan, Singh, Amar, Moore, Meghan E. G., Flanagan, E. Brian, Azimzadeh, Agnes, Burlak, Christopher, Mueller, Kate R., Martins, Kyra, Anazawa, Takayuki, Appakalai, Balamurugan N., Bansal‐Pakala, Pratima, Murtaugh, Michael P., O'Brien, Timothy D., Papas, Klearchos K., Spizzo, Thomas, Schuurman, Henk‐J., Hancock, Wayne W., Hering, Bernhard. J.

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Factors associated with favourable 5 year outcomes in islet transplant alone recipients with type 1 diabetes complicated by severe hypoglycaemia in the Collaborative Islet Transpla... von Hering, Bernhard J., Ballou, Cassandra M., Bellin, Melena D., Payne, Elizabeth H., Kandeel, Fouad, Witkowski, Piotr, Alejandro, Rodolfo, Rickels, Michael R., Barton, Franca B.

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Inhibition of DYRK1A and GSK3B induces human β-cell proliferation von Shen, Weijun, Taylor, Brandon, Jin, Qihui, Nguyen-Tran, Van, Meeusen, Shelly, Zhang, You-Qing, Kamireddy, Anwesh, Swafford, Austin, Powers, Andrew F., Walker, John, Lamb, John, Bursalaya, Badry, DiDonato, Michael, Harb, George, Qiu, Minhua, Filippi, Christophe M., Deaton, Lisa, Turk, Carolina N., Suarez-Pinzon, Wilma L., Liu, Yahu, Hao, Xueshi, Mo, Tingting, Yan, Shanshan, Li, Jing, Herman, Ann E., Hering, Bernhard J., Wu, Tom, Martin Seidel, H., McNamara, Peter, Glynne, Richard, Laffitte, Bryan

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Islet transplantation in the subcutaneous space achieves long-term euglycaemia in preclinical models of type 1 diabetes von Yu, Ming, Agarwal, Divyansh, Korutla, Laxminarayana, May, Catherine L., Wang, Wei, Griffith, Negin Noorchashm, Hering, Bernhard J., Kaestner, Klaus H., Velazquez, Omaida C., Markmann, James F., Vallabhajosyula, Prashanth, Liu, Chengyang, Naji, Ali

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Total Pancreatectomy and Islet Autotransplantation in Children for Chronic Pancreatitis: Indication, Surgical Techniques, Postoperative Management, and Long-Term Outcomes von Chinnakotla, Srinath, Bellin, Melena D, Schwarzenberg, Sarah J, Radosevich, David M, Cook, Marie, Dunn, Ty B, Beilman, Gregory J, Freeman, Martin L, Balamurugan, A N, Wilhelm, Josh, Bland, Barbara, Jimenez-Vega, Jose M, Hering, Bernhard J, Vickers, Selwyn M, Pruett, Timothy L, Sutherland, David E R

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Serum cytokine profiles in healthy nonhuman primates are blunted by sedation and demonstrate sexual dimorphism as detected by a validated multiplex immunoassay von Hocum Stone, Laura, Oppler, Scott Hunter, Nugent, Julia L., Gresch, Sarah, Hering, Bernhard J., Murtaugh, Michael P., Hegstad-Davies, Rebecca L., Ramachandran, Sabarinathan, Graham, Melanie L.

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Efficient production of GGTA1 knockout porcine embryos using a modified handmade cloning (HMC) method von Kumbha, Ramesh, Hosny, Nora, Matson, Anders, Steinhoff, Magie, Hering, Bernhard J., Burlak, Christopher

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Peri-Transplant Inflammation and Long-Term Diabetes Outcomes Were Not Impacted by Either Etanercept or Alpha-1-Antitrypsin Treatment in Islet Autotransplant Recipients von Abdel-Karim, Tasneem R, Hodges, James S, Herold, Kevan C, Pruett, Timothy L, Ramanathan, Karthik V, Hering, Bernhard J, Dunn, Ty B, Kirchner, Varvara A, Beilman, Gregory J, Bellin, Melena D

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Report of the Key Opinion Leaders Meeting on Stem Cell-derived Beta Cells von Odorico, Jon, Markmann, James, Melton, Douglas, Greenstein, Julia, Hwa, Albert, Nostro, Cristina, Rezania, Alireza, Oberholzer, Jose, Pipeleers, Daniel, Yang, Luhan, Cowan, Chad, Huangfu, Danwei, Egli, Dieter, Ben-David, Uri, Vallier, Ludovic, Grey, Shane T, Tang, Qizhi, Roep, Bart, Ricordi, Camilo, Naji, Ali, Orlando, Giuseppe, Anderson, Daniel G, Poznansky, Mark, Ludwig, Barbara, Tomei, Alice, Greiner, Dale L, Graham, Melanie, Carpenter, Melissa, Migliaccio, Giovanni, D’Amour, Kevin, Hering, Bernhard, Piemonti, Lorenzo, Berney, Thierry, Rickels, Mike, Kay, Thomas, Adams, Ann

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Prolonged diabetes reversal after intraportal xenotransplantation of wild-type porcine islets in immunosuppressed nonhuman primates von Hering, Bernhard J, Wijkstrom, Martin, Graham, Melanie L, Hårdstedt, Maria, Aasheim, Tor C, Jie, Tun, Ansite, Jeffrey D, Nakano, Masahiko, Cheng, Jane, Li, Wei, Moran, Kathleen, Christians, Uwe, Finnegan, Colleen, Mills, Charles D, Sutherland, David E, Bansal-Pakala, Pratima, Murtaugh, Michael P, Kirchhof, Nicole, Schuurman, Henk-Jan

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Regulation of the JNK3 signaling pathway during islet isolation: JNK3 and c-fos as new markers of islet quality for transplantation von Abdelli, Saida, Papas, Klearchos K, Mueller, Kate R, Murtaugh, Mike P, Hering, Bernhard J, Bonny, Christophe

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Streptozotocin-Induced Diabetic Nude Mouse Model: Differences between Animals from Different Sources von Graham, Melanie L, Janecek, Jody L, Kittredge, Jessica A, Hering, Bernhard J, Schuurman, Henk-Jan

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