A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in mice von Green, Eric M., Wakimoto, Hiroko, Anderson, Robert L., Evanchik, Marc J., Gorham, Joshua M., Harrison, Brooke C., Henze, Marcus, Kawas, Raja, Oslob, Johan D., Rodriguez, Hector M., Song, Yonghong, Wan, William, Leinwand, Leslie A., Spudich, James A., McDowell, Robert S., Seidman, J. G., Seidman, Christine E.

Volltext

Simultaneous integration of telemetered left-ventricular pressure and echocardiography in rats: Minimally-invasive serial pressure-volume relationships in the setting of normal and... von del Rio, Carlos L., Zambataro, Christopher, Bogie, Heather, Yucel, A.J., Ferguson, Brain, Henze, Marcus P., Fernandes, Sarah, Evanchik, Marc J.

Volltext

Persistent alterations in heart rate variability, baroreflex sensitivity, and anxiety-like behaviors during development of heart failure in the rat von Henze, Marcus, Hart, Davin, Samarel, Allen, Barakat, John, Eckert, Laurie, Scrogin, Karie

Volltext

Integration of Troponin I Phosphorylation With Cardiac Regulatory Networks von Solaro, R John, Henze, Marcus, Kobayashi, Tomoyoshi

Volltext

The Super-Relaxed State and Length Dependent Activation in Porcine Myocardium von Ma, Weikang, Henze, Marcus, Anderson, Robert L., Gong, Henry, Wong, Fiona L., del Rio, Carlos L., Irving, Thomas

Volltext

Deciphering the super relaxed state of human β-cardiac myosin and the mode of action of mavacamten from myosin molecules to muscle fibers von Anderson, Robert L., Trivedi, Darshan V., Sarkar, Saswata S., Henze, Marcus, Ma, Weikang, Gong, Henry, Rogers, Christopher S., Gorham, Joshua M., Wong, Fiona L., Morck, Makenna M., Seidman, Jonathan G., Ruppel, Kathleen M., Irving, Thomas C., Cooke, Roger, Green, Eric M., Spudich, James A.

Volltext

Abstract We094: Acute Administration of The Novel Cardiac Sarcomere Modulator EDG-7500, Improves Ventricular Filling While Preserving LVEF In Dogs with Pacing Induced Left-Ventricu... von Evanchik, Marc, Emter, Craig, Del Rio, carlos, Roof, Steve, St Clair, Sydney, Russell, Alan, Henze, Marcus, Semigran, marc

Volltext

Abstract 4142919: Chronic administration of EDG-7500, a novel sarcomere modulator, prevents increases in cardiac mass, T1 relaxation time, and left ventricular end diastolic pressu... von Emter, Craig, Lehman, Sarah, Lee, Lindsey, DiNatale, Emy, Peter, Angela, Henze, Marcus, Bluemke, David, Tharp, Darla, Roof, Steve, del Rio, Carlos, Semigran, marc, Russell, Alan, Evanchik, Marc

Volltext

Bihemispheric Cerebral FDG PET Correlates of Cognitive Dysfunction as Assessed by the CERAD in Alzheimer's Disease von Schönknecht, Oskar Dieter Peter, Hunt, Aoife, Toro, Pablo, Guenther, Thomas, Henze, Marcus, Haberkorn, Uwe, Schröder, Johannes

Volltext

CRNK gene transfer improves function and reverses the myosin heavy chain isoenzyme switch during post-myocardial infarction left ventricular remodeling von Hart, Davin L, Heidkamp, Maria C, Iyengar, Rekha, Vijayan, Kalpana, Szotek, Erika L, Barakat, John A, Leya, Marysa, Henze, Marcus, Scrogin, Karie, Henderson, Kyle K, Samarel, Allen M

Volltext

Reduction of global longitudinal strain in rats with diastolic dysfunction and preserved ejection fraction: comparison against post-mi rats with reduced ejection fraction von Zambataro, Christopher A., Ferguson, Brian S., Shimkunas, Rafael, Tobia, Steven, Henze, Marcus, Del Rio, Carlos L.

Volltext

Abstract 905: Length Dependent Activation in Porcine Cardiac Myofilaments is Modulated by Mavacamten von Henze, Marcus, Ma, Weikang, Wong, Fiona, Gong, Henry, Anderson, Robert, del Rio, Carlos, Irving, Thomas C

Volltext

Effects of danicamtiv, a novel cardiac myosin activator, in heart failure with reduced ejection fraction: experimental data and clinical results from a phase 2a trial von Voors, Adriaan A., Tamby, Jean‐François, Cleland, John G., Koren, Michael, Forgosh, Leslie B., Gupta, Dinesh, Lund, Lars H., Camacho, Albert, Karra, Ravi, Swart, Henk P., Pellicori, Pierpaolo, Wagner, Frank, Hershberger, Ray E., Prasad, Narayana, Anderson, Robert, Anto, Anu, Bell, Kaylyn, Edelberg, Jay M., Fang, Liang, Henze, Marcus, Kelly, Cynthia, Kurio, Gregory, Li, Wanying, Wells, Kate, Yang, Chun, Teichman, Sam L., Rio, Carlos L., Solomon, Scott D.

Volltext

Abstract 13952: A Novel Genetic Mini-Pig Model of Cardiac Myosin-Binding Protein C (MYBPC3) Dysfunction: Evidence for Altered Sarcomere Structure and Systolic/Diastolic Functional... von del Rio, Carlos L, Ma, Weikang, Ryba, David, Gong, Henry, Henze, Marcus, Gollapudi, Sampath K, Anderson, Robert, Nag, Suman, Rogers, Christopher, Irving, Thomas

Volltext

Chronic fluoxetine reduces autonomic control of cardiac rhythms in rats with congestive heart failure von Henze, Marcus, Tiniakov, Ruslan, Samarel, Allen, Holmes, Earle, Scrogin, Karie

Volltext

Myofilament Length Dependent Activation in Porcine Cardiac Muscle von Ma, Weikang, Anderson, Robert, Henze, Marcus, Gong, Henry, Wong, Fiona, del Rio, Carlos, Irving, Thomas

Volltext

Abstract 17492: Chronic Treatment With a Mavacamten-Like Myosin-Modulator (MYK-581) Prevents Left-Atrial Remodeling, Decreases Cardiac Troponin Leakage, and Blunts Mortality in a M... von Bell, Kaylyn M, Ryba, David M, Smit, Trisha, Rohret, Frank, Chin, Daniel, Hollenbeck, Emily, Shahidi-Latham, Sheerin, Henze, Marcus, del Rio, Carlos L

Volltext

Isoflurane Anesthesia Masks Elevated Filling Pressures in Hypertensive Rats with Diastolic Dysfunction and Preserved Ejection Fraction: Comparison to Ketamine/Xylaxine Sedation von Zambataro, Christopher A., Ferguson, Brian S., Henze, Marcus P., Evanchik, Marc J., Del Rio, Carlos L.

Volltext

Reduced cerebral glucose metabolism in patients at risk for Alzheimer's disease von Hunt, Aoife, Schönknecht, Peter, Henze, Marcus, Seidl, Ulrich, Haberkorn, Uwe, Schröder, Johannes

Volltext

Cardiac muscle function across the natural history of a genetic minipig model of hypertrophic cardiomyopathy von Henze, Marcus, Anderson, Robert, Wong, Fiona, Weiss, Robert, Divekar, Abhay, Meyerholz, David, Ahmad, Ferhaan, Green, Eric

Volltext