Functional profile of a novel modulator of serotonin, dopamine, and glutamate neurotransmission von Snyder, Gretchen L., Vanover, Kimberly E., Zhu, Hongwen, Miller, Diane B., O’Callaghan, James P., Tomesch, John, Li, Peng, Zhang, Qiang, Krishnan, Vaishnav, Hendrick, Joseph P., Nestler, Eric J., Davis, Robert E., Wennogle, Lawrence P., Mates, Sharon

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Discovery of a Tetracyclic Quinoxaline Derivative as a Potent and Orally Active Multifunctional Drug Candidate for the Treatment of Neuropsychiatric and Neurological Disorders von Li, Peng, Zhang, Qiang, Robichaud, Albert J, Lee, Taekyu, Tomesch, John, Yao, Wei, Beard, J. David, Snyder, Gretchen L, Zhu, Hongwen, Peng, Youyi, Hendrick, Joseph P, Vanover, Kimberly E, Davis, Robert E, Mates, Sharon, Wennogle, Lawrence P

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Muscarinic receptors acting at pre- and post-synaptic sites differentially regulate dopamine/DARPP-32 signaling in striatonigral and striatopallidal neurons von Kuroiwa, Mahomi, Hamada, Miho, Hieda, Eriko, Shuto, Takahide, Sotogaku, Naoki, Flajolet, Marc, Snyder, Gretchen L., Hendrick, Joseph P., Fienberg, Allen, Nishi, Akinori

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In vivo observation of polypeptide flux through the bacterial chaperonin system von Ewalt, K L, Hendrick, J P, Houry, W A, Hartl, F U

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Acute Enhancement of Cardiac Function by Phosphodiesterase Type 1 Inhibition: Translational Study in the Dog and Rabbit von Hashimoto, Toru, Kim, Grace E, Tunin, Richard S, Adesiyun, Tolulope, Hsu, Steven, Nakagawa, Ryo, Zhu, Guangshuo, O’Brien, Jennifer J, Hendrick, Joseph P, Davis, Robert E, Yao, Wei, Beard, David, Hoxie, Helen R, Wennogle, Lawrence P, Lee, Dong I, Kass, David A

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Discovery of Potent and Selective Inhibitors of Phosphodiesterase 1 for the Treatment of Cognitive Impairment Associated with Neurodegenerative and Neuropsychiatric Diseases von Li, Peng, Zheng, Hailin, Zhao, Jun, Zhang, Lei, Yao, Wei, Zhu, Hongwen, Beard, J. David, Ida, Koh, Lane, Weston, Snell, Gyorgy, Sogabe, Satoshi, Heyser, Charles J, Snyder, Gretchen L, Hendrick, Joseph P, Vanover, Kimberly E, Davis, Robert E, Wennogle, Lawrence P

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Inhibition of calcium-calmodulin-dependent phosphodiesterase (PDE1) suppresses inflammatory responses von O'Brien, Jennifer J., O'Callaghan, James P., Miller, Diane B., Chalgeri, Suman, Wennogle, Lawrence P., Davis, Robert E., Snyder, Gretchen L., Hendrick, Joseph P.

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Preclinical profile of ITI-214, an inhibitor of phosphodiesterase 1, for enhancement of memory performance in rats von Snyder, Gretchen L., Prickaerts, Jos, Wadenberg, Marie-Louise, Zhang, Lei, Zheng, Hailin, Yao, Wei, Akkerman, Sven, Zhu, Hongwen, Hendrick, Joseph P., Vanover, Kimberly E., Davis, Robert, Li, Peng, Mates, Sharon, Wennogle, Lawrence P.

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Acute Enhancement of Cardiac Function by Phosphodiesterase Type 1 Inhibition von Hashimoto, Toru, Kim, Grace E, Tunin, Richard S, Adesiyun, Tolulope, Hsu, Steven, Nakagawa, Ryo, Zhu, Guangshuo, O'Brien, Jennifer J, Hendrick, Joseph P, Davis, Robert E, Yao, Wei, Beard, David, Hoxie, Helen R, Wennogle, Lawrence P, Lee, Dong I, Kass, David A

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Mass Spectrometry of Ribosomes and Ribosomal Subunits von Benjamin, Dennis R., Robinson, Carol V., Hendrick, Joseph P., Hartl, F. Ulrich, Dobson, Christopher M.

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General anesthetics selectively modulate glutamatergic and dopaminergic signaling via site-specific phosphorylation in vivo von Snyder, Gretchen L., Galdi, Stacey, Hendrick, Joseph P., Hemmings, Hugh C.

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Nerve agent exposure elicits site-specific changes in protein phosphorylation in mouse brain von Zhu, Hongwen, O'Brien, Jennifer J, O'Callaghan, James P, Miller, Diane B, Zhang, Qiang, Rana, Minal, Tsui, Tiffany, Peng, Youyi, Tomesch, John, Hendrick, Joseph P, Wennogle, Lawrence P, Snyder, Gretchen L

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ITI-007: A NOVEL THERAPY FOR THE TREATMENT OF SCHIZOPHRENIA AND RELATED PSYCHOSES von Vanover, Kimberly E, Snyder, Gretchen L, Hendrick, Joseph P, Fienberg, Allen A, Wennogle, Lawrence P, Mates, Sharon, Davis, Robert E

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Discovery of (S) -2 -( (S) -2 -(3,5 -difluorophenyl ) -2-hydroxyacetamido ) -N-( (S,Z) -3 -methyl -4 -oxo -4,5 -dihydro -3H-benzo[d|[1,2 ]diazepin -5 -yl )propanamide (BMS -433796... von PRASAD, C. V. C, MING ZHENG, LOO, Alice, JIAN WANG, SLECZKA, Bogdan G, DANGLER, Charles, ROBERTSON, Barbara J, HENDRICK, Joseph P, ROBERTS, Susan B, BARTEN, Donna M, VIG, Shikha, BERGSTROM, Carl, SMITH, David W, QI GAO, YEOLA, Suresh, POLSON, Craig T, CORSA, Jason A, GUSS, Valerie L

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Control of Folding and Membrane Translocation by Binding of the Chaperone DnaJ to Nascent Polypeptides von Hendrick, Joseph P., Langer, Thomas, Davis, Terri A., Hartl, F. Ulrich, Wiedmann, Martin

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SUPPRESSION OF CNS INFLAMMATION BY PHOSPHODIESTERASE-1 (PDE1) INHIBITORS: TOWARD NEW TREATMENTS FOR NEURODEGENERATIVE DISEASES von Snyder, Gretchen L., Dutheil, Sophie, O'Brien, Jennifer L., Cruz, Stephanie, Tian, Yuan, Hendrick, Joseph P., Wennogle, Lawrence P., Davis, Robert E.

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Molecular Chaperone Functions of Heat-Shock Proteins von Hendrick, J P, Hartl, F

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The binding cascade of SecB to SecA to SecY/E mediates preprotein targeting to the E. coli plasma membrane von HARTL, F.-U, LECKER, S, SCHIEBEL, E, HENDRICK, J. P, WICKNER, W

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The purified E. coli integral membrane protein SecY/E is sufficient for reconstitution of SecA-dependent precursor protein translocation von BRUNDAGE, L, HENDRICK, J. P, SCHIEBEL, E, DRIESSEN, A. J. M, WICKNER, W

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SecA protein needs both acidic phospholipids and SecY/E protein for functional high-affinity binding to the Escherichia coli plasma membrane von HENDRICK, J. P, WICKNER, W

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