Translation Regulation as a Therapeutic Target in Cancer von GRZMIL, Michal, HEMMINGS, Brian A

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PKB and the mitochondria: AKTing on apoptosis von Parcellier, Arnaud, Tintignac, Lionel A., Zhuravleva, Elena, Hemmings, Brian A.

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Acentrosomal spindle organization renders cancer cells dependent on the kinesin HSET von Kleylein-Sohn, Julia, Pöllinger, Bernadette, Ohmer, Michaela, Hofmann, Francesco, Nigg, Erich A, Hemmings, Brian A, Wartmann, Markus

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Identification of a PKB/Akt Hydrophobic Motif Ser-473 Kinase as DNA-dependent Protein Kinase von Feng, Jianhua, Park, Jongsun, Cron, Peter, Hess, Daniel, Hemmings, Brian A.

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S6K inhibition renders cardiac protection against myocardial infarction through PDK1 phosphorylation of Akt von Di, Ruomin, Wu, Xiangqi, Chang, Zai, Zhao, Xia, Feng, Qiuting, Lu, Shuangshuang, Luan, Qing, Hemmings, Brian A, Li, Xinli, Yang, Zhongzhou

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SYK inhibition blocks proliferation and migration of glioma cells and modifies the tumor microenvironment von Moncayo, Gerald, Grzmil, Michal, Smirnova, Tatiana, Zmarz, Pawel, Huber, Roland M, Hynx, Debby, Kohler, Hubertus, Wang, Yuhua, Hotz, Hans-Rudolf, Hynes, Nancy E, Keller, Georg, Frank, Stephan, Merlo, Adrian, Hemmings, Brian A

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Mammalian NDR/LATS protein kinases in hippo tumor suppressor signaling von Hergovich, Alexander, Hemmings, Brian A.

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Downstream of human NDR kinases: Impacting on c-myc and p21 protein stability to control cell cycle progression von Cornils, Hauke, Kohler, Reto S., Hergovich, Alexander, Hemmings, Brian A.

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The MST1 and hMOB1 Tumor Suppressors Control Human Centrosome Duplication by Regulating NDR Kinase Phosphorylation von Hergovich, Alexander, Kohler, Reto S., Schmitz, Debora, Vichalkovski, Anton, Cornils, Hauke, Hemmings, Brian A.

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Deltex-1 activates mitotic signaling and proliferation and increases the clonogenic and invasive potential of U373 and LN18 glioblastoma cells and correlates with patient survival von Huber, Roland M, Rajski, Michal, Sivasankaran, Balasubramanian, Moncayo, Gerald, Hemmings, Brian A, Merlo, Adrian

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PI3K-PKB/Akt pathway von Hemmings, Brian A, Restuccia, David F

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Regulation of protein kinase cascades by protein phosphatase 2A von Millward, Thomas A, Zolnierowicz, Stanislaw, Hemmings, Brian A

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Molecular Mechanism for the Regulation of Protein Kinase B/Akt by Hydrophobic Motif Phosphorylation von Yang, Jing, Cron, Peter, Thompson, Vivienne, Good, Valerie M., Hess, Daniel, Hemmings, Brian A., Barford, David

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In Vivo Analysis of Protein Kinase B (PKB)/Akt Regulation in DNA-PKcs-null Mice Reveals a Role for PKB/Akt in DNA Damage Response and Tumorigenesis von Surucu, Banu, Bozulic, Lana, Hynx, Debby, Parcellier, Arnaud, Hemmings, Brian A.

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The endogenous inhibitor of Akt, CTMP, is critical to ischemia-induced neuronal death von Zukin, R Suzanne, Ofengeim, Dimitry, Hemmings, Brian A, Noh, Kyung-Min, Follenzi, Antonia, Latuszek-Barrantes, Adrianna, Miyawaki, Takahiro

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Only Akt1 Is Required for Proliferation, while Akt2 Promotes Cell Cycle Exit through p21 Binding von Héron-Milhavet, Lisa, Franckhauser, Celine, Rana, Vanessa, Berthenet, Cyril, Fisher, Daniel, Hemmings, Brian A, Fernandez, Anne, Lamb, Ned J C

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PIKKing on PKB: regulation of PKB activity by phosphorylation von Bozulic, Lana, Hemmings, Brian A

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Mammalian NDR protein kinases: From regulation to a role in centrosome duplication von Hergovich, Alexander, Cornils, Hauke, Hemmings, Brian A.

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DNA-dependent Protein Kinase-mediated Phosphorylation of Protein Kinase B Requires a Specific Recognition Sequence in the C-terminal Hydrophobic Motif von Park, Jongsun, Feng, Jianhua, Li, Yuwen, Hammarsten, Ola, Brazil, Derek P., Hemmings, Brian A.

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Human NDR Kinases Are Rapidly Activated by MOB Proteins through Recruitment to the Plasma Membrane and Phosphorylation von Hergovich, Alexander, Bichsel, Samuel J., Hemmings, Brian A.

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