Multivalent IgM scaffold enhances the therapeutic potential of variant-agnostic ACE2 decoys against SARS-CoV-2 von Verstraete, Meghan M, Heinkel, Florian, Li, Janessa, Cao, Siran, Tran, Anh, Halverson, Elizabeth C, Gene, Robert, Stangle, Elizabeth, Silva-Moreno, Begonia, Arrafi, Sifa, Bavananthasivam, Jegarubee, Fung, Madeline, Eji-Lasisi, Mariam, Masterman, Stephanie, Xanthoudakis, Steve, Dixit, Surjit, Babcook, John, Clavette, Brandon, Fogg, Mark, Escobar-Cabrera, Eric

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Engineering a pure and stable heterodimeric IgA for the development of multispecific therapeutics von Heinkel, Florian, Verstraete, Meghan M, Cao, Siran, Li, Janessa, Farber, Patrick, Stangle, Elizabeth, Silva-Moreno, Begonia, Peng, Fangni, Dixit, Surjit, Boulanger, Martin J, Spreter Von Kreudenstein, Thomas, Escobar-Cabrera, Eric

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Topological Dissection of the Membrane Transport Protein Mhp1 Derived from Cysteine Accessibility and Mass Spectrometry von Calabrese, Antonio N, Jackson, Scott M, Jones, Lynsey N, Beckstein, Oliver, Heinkel, Florian, Gsponer, Joerg, Sharples, David, Sans, Marta, Kokkinidou, Maria, Pearson, Arwen R, Radford, Sheena E, Ashcroft, Alison E, Henderson, Peter J. F

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Determination of Protein Folding Intermediate Structures Consistent with Data from Oxidative Footprinting Mass Spectrometry von Heinkel, Florian, Gsponer, Jörg

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Conformational Plasticity and DNA-Binding Specificity of the Eukaryotic Transcription Factor Pax5 von Perez-Borrajero, Cecilia, Heinkel, Florian, Gsponer, Jörg, McIntosh, Lawrence P

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Phase separation and clustering of an ABC transporter in Mycobacterium tuberculosis von Heinkel, Florian, Abraham, Libin, Ko, Mary, Chao, Joseph, Bach, Horacio, Hui, Lok Tin, Li, Haoran, Zhu, Mang, Ling, Yeou Mei, Rogalski, Jason C., Scurll, Joshua, Bui, Jennifer M., Mayor, Thibault, Gold, Michael R., Chou, Keng C., Av-Gay, Yossef, McIntosh, Lawrence P., Gsponer, Jörg

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Abstract 924: PROTECT, a novel antibody platform for integrating tumor-specific immune modulation and enhancing the therapeutic window of targeted multispecific biologics von Dixit, Surjit, Heinkel, Florian, Von Rossum, Anna, Pratap, Harsh, Arrafi, Sifa, Rahim, Javairia, Bhojane, Purva, Stangle, Liz, Stenberg, Leisa, Volkers, Gesa, Escobar-Cabrera, Eric, Spreter, Thomas

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Characterization of the Pilotin-Secretin Complex from the Salmonella enterica Type III Secretion System Using Hybrid Structural Methods von Majewski, Dorothy D., Okon, Mark, Heinkel, Florian, Robb, Craig S., Vuckovic, Marija, McIntosh, Lawrence P., Strynadka, Natalie C.J.

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Biophysical Characterization of the Tandem FHA Domain Regulatory Module from the Mycobacterium tuberculosis ABC Transporter Rv1747 von Heinkel, Florian, Shen, Leo, Richard-Greenblatt, Melissa, Okon, Mark, Bui, Jennifer M., Gee, Christine L., Gay, Laurie M., Alber, Tom, Av-Gay, Yossef, Gsponer, Jörg, McIntosh, Lawrence P.

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Systems-wide Identification of cis-Regulatory Elements in Proteins von Yeon, Ju Hun, Heinkel, Florian, Sung, Minhui, Na, Dokyun, Gsponer, Jörg

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Abstract 2926: PROTECTTM, a novel trispecific antibody masking platform with integrated immune modulation displays unique activity and differentiated modes of action von von Rossum, Anna, Desjardins, Genevieve, Escalante, Nichole, Wong, Wingkie, Harbourne, Bryant, Li, Janessa, Moreno, Begonia Silva, Raghunatha, Prajwal, Kunze, Richard, Fung, Madeline, Heinkel, Florian, Pratap, Harsh, Haworth, Kevin, Escobar-Cabrera, Eric, Clavette, Brandon, Dixit, Surjit, Weisser, Nina, von Kreudenstein, Thomas Spreter

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HETERODIMERIC IGA FC CONSTRUCTS AND METHODS OF USE THEREOF von ESCOBAR-CABRERA, Eric, HEINKEL, Florian, DIXIT, Surjit Bhimarao, VERSTRAETE, Meghan Marie, SPRETER VON KREUDENSTEIN, Thomas

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MULTIVALENT POLYPEPTIDE CONSTRUCTS CAPABLE OF BINDING VIRAL SPIKE PROTEINS AND METHODS OF USING THE SAME von Dixit, Surjit Bhimarao, Verstraete, Meghan Marie, Heinkel, Florian, Escobar-Cabrera, Eric

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HETERODIMERIC IGA FC CONSTRUCTS AND METHODS OF USE THEREOF von Dixit, Surjit Bhimarao, Verstraete, Meghan Marie, Heinkel, Florian, Spreter Von Kreudenstein, Thomas, Escobar-Cabrera, Eric

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MULTIVALENT POLYPEPTIDE CONSTRUCTS CAPABLE OF BINDING VIRAL SPIKE PROTEINS AND METHODS OF USING THE SAME von ESCOBAR-CABRERA, Eric, HEINKEL, Florian, DIXIT, Surjit Bhimarao, VERSTRAETE, Meghan Marie

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MULTIVALENT POLYPEPTIDE CONSTRUCTS CAPABLE OF BINDING VIRAL SPIKE PROTEINS AND METHODS OF USING THE SAME von ESCOBAR-CABRERA, Eric, HEINKEL, Florian, DIXIT, Surjit Bhimarao, VERSTRAETE, Meghan Marie

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HETERODIMERIC IGA FC CONSTRUCTS AND METHODS OF USE THEREOF von Dixit, Surjit Bhimarao, Verstraete, Meghan Marie, Heinkel, Florian, Spreter Von Kreudenstein, Thomas, Escobar-Cabrera, Eric

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FUSION PROTEINS COMPRISING A LIGAND-RECEPTOR PAIR AND A BIOLOGICALLY FUNCTIONAL PROTEIN von VOLKERS, Gesa, VON ROSSUM, Anna, ESCOBAR-CABRERA, Eric, HEINKEL, Florian, DIXIT, Surjit Bhimarao, SPRETER VON KREUDENSTEIN, Thomas

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HETERODIMERIC IGA FC CONSTRUCTS AND METHODS OF USE THEREOF von ESCOBAR-CABRERA, Eric, HEINKEL, Florian, DIXIT, Surjit Bhimarao, VERSTRAETE, Meghan Marie, SPRETER VON KREUDENSTEIN, Thomas

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HETERODIMERIC IGA FC CONSTRUCTS AND METHODS OF USE THEREOF von ESCOBAR-CABRERA, Eric, HEINKEL, Florian, DIXIT, Surjit Bhimarao, VERSTRAETE, Meghan Marie, SPRETER VON KREUDENSTEIN, Thomas

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