Role of the immediate early response 3 (IER3) gene in cellular stress response, inflammation and tumorigenesis von Arlt, Alexander, Schäfer, Heiner

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The Role of Nrf2 in the Regulation of Mitochondrial Function and Ferroptosis in Pancreatic Cancer von Baiskhanova, Dinara, Schäfer, Heiner

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Translational regulation of specific mRNAs controls feedback inhibition and survival during macrophage activation von Schott, Johanna, Reitter, Sonja, Philipp, Janine, Haneke, Katharina, Schäfer, Heiner, Stoecklin, Georg

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Diabetes as risk factor for pancreatic cancer: Hyperglycemia promotes epithelial-mesenchymal-transition and stem cell properties in pancreatic ductal epithelial cells von Rahn, Sascha, Zimmermann, Vivien, Viol, Fabrice, Knaack, Hendrike, Stemmer, Kerstin, Peters, Lena, Lenk, Lennart, Ungefroren, Hendrik, Saur, Dieter, Schäfer, Heiner, Helm, Ole, Sebens, Susanne

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Tumor‐associated macrophages exhibit pro‐ and anti‐inflammatory properties by which they impact on pancreatic tumorigenesis von Helm, Ole, Held‐Feindt, Janka, Grage‐Griebenow, Evelin, Reiling, Norbert, Ungefroren, Hendrik, Vogel, Ilka, Krüger, Uwe, Becker, Thomas, Ebsen, Michael, Röcken, Christoph, Kabelitz, Dieter, Schäfer, Heiner, Sebens, Susanne

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Cytoprotection "gone astray": Nrf2 and its role in cancer von Geismann, Claudia, Arlt, Alexander, Sebens, Susanne, Schäfer, Heiner

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The Crosstalk between Nrf2 and TGF-β1 in the Epithelial-Mesenchymal Transition of Pancreatic Duct Epithelial Cells von Arfmann-Knübel, Sarah, Struck, Birte, Genrich, Geeske, Helm, Ole, Sipos, Bence, Sebens, Susanne, Schäfer, Heiner

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TRAIL-receptor 2—a novel negative regulator of p53 von Willms, Anna, Schupp, Hella, Poelker, Michelle, Adawy, Alshaimaa, Debus, Jan Frederik, Hartwig, Torsten, Krichel, Tim, Fritsch, Jürgen, Singh, Steven, Walczak, Henning, von Karstedt, Silvia, Schäfer, Heiner, Trauzold, Anna

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NF-κB/RelA controlled A20 limits TRAIL-induced apoptosis in pancreatic cancer von Geismann, Claudia, Hauser, Charlotte, Grohmann, Frauke, Schneeweis, Christian, Bölter, Nico, Gundlach, Jan-Paul, Schneider, Günter, Röcken, Christoph, Meinhardt, Christian, Schäfer, Heiner, Schreiber, Stefan, Arlt, Alexander

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Impact of the Monocarboxylate Transporter-1 (MCT1)-Mediated Cellular Import of Lactate on Stemness Properties of Human Pancreatic Adenocarcinoma Cells von Sandforth, Leontine, Ammar, Nourhane, Dinges, Lisa Antonia, Röcken, Christoph, Arlt, Alexander, Sebens, Susanne, Schäfer, Heiner

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Expression and role of the immune checkpoint regulator PD-L1 in the tumor-stroma interplay of pancreatic ductal adenocarcinoma von Daunke, Tina, Beckinger, Silje, Rahn, Sascha, Krüger, Sandra, Heckl, Steffen, Schäfer, Heiner, Wesch, Daniela, Pilarsky, Christian, Eckstein, Markus, Hartmann, Arndt, Röcken, Christoph, Wandmacher, Anna Maxi, Sebens, Susanne

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Role of NF-κB and Akt/PI3K in the resistance of pancreatic carcinoma cell lines against gemcitabine-induced cell death von Arlt, Alexander, Gehrz, Andre, Müerköster, Susanne, Vorndamm, Jens, Kruse, Marie-Luise, Fölsch, Ulrich R, Schäfer, Heiner

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Comparative characterization of stroma cells and ductal epithelium in chronic pancreatitis and pancreatic ductal adenocarcinoma von Helm, Ole, Mennrich, Ruben, Petrick, Domantas, Goebel, Lisa, Freitag-Wolf, Sandra, Röder, Christian, Kalthoff, Holger, Röcken, Christoph, Sipos, Bence, Kabelitz, Dieter, Schäfer, Heiner, Oberg, Hans-Heinrich, Wesch, Daniela, Sebens, Susanne

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Hepatic myofibroblasts exert immunosuppressive effects independent of the immune checkpoint regulator PD-L1 in liver metastasis of pancreatic ductal adenocarcinoma von Beckinger, Silje, Daunke, Tina, Aldag, Leon, Krüger, Sandra, Heckl, Steffen, Wesch, Daniela, Schäfer, Heiner, Röcken, Christoph, Rahn, Sascha, Sebens, Susanne

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Up-regulation of L1CAM in Pancreatic Duct Cells Is Transforming Growth Factor β1- and Slug-Dependent: Role in Malignant Transformation of Pancreatic Cancer von GEISMANN, Claudia, MORSCHECK, Mascha, FÖLSCH, Ulrich R, SCHÄFER, Heiner, MÜERKÖSTER, Susanne Sebens, KOCH, Dorothee, BERGMANN, Frank, UNGEFROREN, Hendrik, ARLT, Alexander, TSAO, Ming-Sound, BACHEM, Max G, ALTEVOGT, Peter, SIPOS, Bence

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Monocarboxylate Transporter-1 (MCT1)-Mediated Lactate Uptake Protects Pancreatic Adenocarcinoma Cells from Oxidative Stress during Glutamine Scarcity Thereby Promoting Resistance a... von Ammar, Nourhane, Hildebrandt, Maya, Geismann, Claudia, Röder, Christian, Gemoll, Timo, Sebens, Susanne, Trauzold, Ania, Schäfer, Heiner

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Combined treatment of L1CAM antibodies and cytostatic drugs improve the therapeutic response of pancreatic and ovarian carcinoma von Schäfer, Heiner, Dieckmann, Chantal, Korniienko, Olena, Moldenhauer, Gerhard, Kiefel, Helena, Salnikov, Alexey, Krüger, Achim, Altevogt, Peter, Sebens, Susanne

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Colonic Lamina Propria Inflammatory Cells from Patients with IBD Induce the Nuclear Factor-E2 Related Factor-2 Thereby Leading to Greater Proteasome Activity and Apoptosis Protecti... von Kruse, Marie-Luise, Friedrich, Martin, Arlt, Alexander, Röcken, Christoph, Egberts, Jan-Hendrik, Sebens, Susanne, Schäfer, Heiner

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Tumor stroma interactions induce chemoresistance in pancreatic ductal carcinoma cells involving increased secretion and paracrine effects of nitric oxide and interleukin-1β von MÜERKÖSTER, Susanne, WEGEHENKEL, Kai, SCHÄFER, Heiner, ARLT, Alexander, WITT, Maike, SIPOS, Bence, KRUSE, Marie-Luise, SEBENS, Thorsten, KLÖPPEL, Günter, KALTHOFF, Holger, FÖLSCH, Ulrich R

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The hepatic microenvironment essentially determines tumor cell dormancy and metastatic outgrowth of pancreatic ductal adenocarcinoma von Lenk, Lennart, Pein, Maren, Will, Olga, Gomez, Beatriz, Viol, Fabrice, Hauser, Charlotte, Egberts, Jan-Hendrik, Gundlach, Jan-Paul, Helm, Ole, Tiwari, Sanjay, Weiskirchen, Ralf, Rose-John, Stefan, Röcken, Christoph, Mikulits, Wolfgang, Wenzel, Patrick, Schneider, Günter, Saur, Dieter, Schäfer, Heiner, Sebens, Susanne

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