Glioma epigenetics: From subclassification to novel treatment options von Gusyatiner, Olga, Hegi, Monika E.

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EANO guidelines on the diagnosis and treatment of diffuse gliomas of adulthood von Weller, Michael, van den Bent, Martin, Preusser, Matthias, Le Rhun, Emilie, Tonn, Jörg C., Minniti, Giuseppe, Bendszus, Martin, Balana, Carmen, Chinot, Olivier, Dirven, Linda, French, Pim, Hegi, Monika E., Jakola, Asgeir S., Platten, Michael, Roth, Patrick, Rudà, Roberta, Short, Susan, Smits, Marion, Taphoorn, Martin J. B., von Deimling, Andreas, Westphal, Manfred, Soffietti, Riccardo, Reifenberger, Guido, Wick, Wolfgang

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Interrogation of the Microenvironmental Landscape in Brain Tumors Reveals Disease-Specific Alterations of Immune Cells von Klemm, Florian, Maas, Roeltje R., Bowman, Robert L., Kornete, Mara, Soukup, Klara, Nassiri, Sina, Brouland, Jean-Philippe, Iacobuzio-Donahue, Christine A., Brennan, Cameron, Tabar, Viviane, Gutin, Philip H., Daniel, Roy T., Hegi, Monika E., Joyce, Johanna A.

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Glioblastoma in adults: a Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) consensus review on current management and future directions von Wen, Patrick Y, Weller, Michael, Lee, Eudocia Quant, Alexander, Brian M, Barnholtz-Sloan, Jill S, Barthel, Floris P, Batchelor, Tracy T, Bindra, Ranjit S, Chang, Susan M, Chiocca, E Antonio, Cloughesy, Timothy F, DeGroot, John F, Galanis, Evanthia, Gilbert, Mark R, Hegi, Monika E, Horbinski, Craig, Huang, Raymond Y, Lassman, Andrew B, Le Rhun, Emilie, Lim, Michael, Mehta, Minesh P, Mellinghoff, Ingo K, Minniti, Giuseppe, Nathanson, David, Platten, Michael, Preusser, Matthias, Roth, Patrick, Sanson, Marc, Schiff, David, Short, Susan C, Taphoorn, Martin J B, Tonn, Joerg-Christian, Tsang, Jonathan, Verhaak, Roel G W, von Deimling, Andreas, Wick, Wolfgang, Zadeh, Gelareh, Reardon, David A, Aldape, Kenneth D, van den Bent, Martin J

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Sensitivity Analysis of the MGMT-STP27 Model and Impact of Genetic and Epigenetic Context to Predict the MGMT Methylation Status in Gliomas and Other Tumors von Bady, Pierre, Delorenzi, Mauro, Hegi, Monika E

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MGMT promoter methylation status testing to guide therapy for glioblastoma: refining the approach based on emerging evidence and current challenges von Mansouri, Alireza, Hachem, Laureen D, Mansouri, Sheila, Nassiri, Farshad, Laperriere, Normand J, Xia, Daniel, Lindeman, Neal I, Wen, Patrick Y, Chakravarti, Arnab, Mehta, Minesh P, Hegi, Monika E, Stupp, Roger, Aldape, Kenneth D, Zadeh, Gelareh

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Temozolomide versus standard 6-week radiotherapy versus hypofractionated radiotherapy in patients older than 60 years with glioblastoma: the Nordic randomised, phase 3 trial von Malmström, Annika, Dr, Grønberg, Bjørn Henning, PhD, Marosi, Christine, MD, Stupp, Roger, MD, Frappaz, Didier, MD, Schultz, Henrik, MD, Abacioglu, Ufuk, MD, Tavelin, Björn, BSc, Lhermitte, Benoit, MD, Hegi, Monika E, PhD, Rosell, Johan, MSc, Henriksson, Roger, Prof

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Dose-Dense Temozolomide for Newly Diagnosed Glioblastoma: A Randomized Phase III Clinical Trial von GILBERT, Mark R, MEIHUA WANG, MAHAJAN, Anita, SCHULTZ, Christopher J, ERRIDGE, Sara, BAUMERT, Brigitta, HOPKINS, Kristen I, TZUK-SHINA, Tzahala, BROWN, Paul D, CHAKRAVARTI, Arnab, CURRAN, Walter J, MEHTA, Minesh P, ALDAPE, Kenneth D, STUPP, Roger, HEGI, Monika E, JAECKLE, Kurt A, ARMSTRONG, Terri S, WEFEL, Jeffrey S, MINHEE WON, BLUMENTHAL, Deborah T

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Chemoradiotherapy in Malignant Glioma: Standard of Care and Future Directions von Stupp, Roger, Hegi, Monika E, Gilbert, Mark R, Chakravarti, Arnab

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Ubiquitin Specific Peptidase 15 (USP15) suppresses glioblastoma cell growth via stabilization of HECTD1 E3 ligase attenuating WNT pathway activity von Oikonomaki, Maria, Bady, Pierre, Hegi, Monika E.

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Molecular neuro-oncology in clinical practice: a new horizon von Weller, Michael, Prof, Pfister, Stefan M, MD, Wick, Wolfgang, Prof, Hegi, Monika E, PhD, Reifenberger, Guido, Prof, Stupp, Roger, Prof

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Phase I/IIa Study of Cilengitide and Temozolomide With Concomitant Radiotherapy Followed by Cilengitide and Temozolomide Maintenance Therapy in Patients With Newly Diagnosed Gliobl... von STUPP, Roger, HEGI, Monika E, PIETSCH, Torsten, HICKING, Christine, TONN, Joerg-Christian, DISERENS, Annie-Claire, PICA, Alessia, HERMISSON, Mirjam, KRUEGER, Stefan, PICARD, Martin, WELLER, Michael, NEYNS, Bart, GOLDBRUNNER, Roland, SCHLEGEL, Uwe, CLEMENT, Paul M. J, GRABENBAUER, Gerhard G, OCHSENBEIN, Adrian F, SIMON, Matthias, DIETRICH, Pierre-Yves

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Stem Cell–Related “Self-Renewal” Signature and High Epidermal Growth Factor Receptor Expression Associated With Resistance to Concomitant Chemoradiotherapy in Glioblastoma von MURAT, Anastasia, MIGLIAVACCA, Eugenia, HAINFELLNER, Johannes A, HEPPNER, Frank L, DIETRICH, Pierre-Yves, ZIMMER, Yitzhak, CAIRNCROSS, J. Gregory, JANZER, Robert-Charles, DOMANY, Eytan, DELORENZI, Mauro, STUPP, Roger, HEGI, Monika E, GORLIA, Thierry, LAMBIV, Wanyu L, SHAY, Tal, HAMOU, Marie-France, DE TRIBOLET, Nicolas, REGLI, Luca, WICK, Wolfgang, KOUWENHOVEN, Mathilde C. M

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Nomograms for predicting survival of patients with newly diagnosed glioblastoma: prognostic factor analysis of EORTC and NCIC trial 26981-22981/CE.3 von Gorlia, Thierry, Dr, van den Bent, Martin J, MD, Hegi, Monika E, PhD, Mirimanoff, René O, MD, Weller, Michael, MD, Cairncross, J Gregory, MD, Eisenhauer, Elizabeth, MD, Belanger, Karl, MD, Brandes, Alba A, MD, Allgeier, Anouk, PhD, Lacombe, Denis, MD, Stupp, Roger, MD

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Is more better? The impact of extended adjuvant temozolomide in newly diagnosed glioblastoma: a secondary analysis of EORTC and NRG Oncology/RTOG von Blumenthal, Deborah T, Gorlia, Thierry, Gilbert, Mark R, Kim, Michelle M, Burt Nabors, L, Mason, Warren P, Hegi, Monika E, Zhang, Peixin, Golfinopoulos, Vassilis, Perry, James R, Hyun Nam, Do, Erridge, Sara C, Corn, Benjamin W, Mirimanoff, René O, Brown, Paul D, Baumert, Brigitta G, Mehta, Minesh P, van den Bent, Martin J, Reardon, David A, Weller, Michael, Stupp, Roger

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Hyperpolarized 13C-glucose magnetic resonance highlights reduced aerobic glycolysis in vivo in infiltrative glioblastoma von Mishkovsky, Mor, Gusyatiner, Olga, Lanz, Bernard, Cudalbu, Cristina, Vassallo, Irene, Hamou, Marie-France, Bloch, Jocelyne, Comment, Arnaud, Gruetter, Rolf, Hegi, Monika E.

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BET protein inhibition sensitizes glioblastoma cells to temozolomide treatment by attenuating MGMT expression von Tancredi, Alessandro, Gusyatiner, Olga, Bady, Pierre, Buri, Michelle C., Lomazzi, Rémy, Chiesi, Davide, Messerer, Mahmoud, Hegi, Monika E.

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Modulation of angiogenic and inflammatory response in glioblastoma by hypoxia von Murat, Anastasia, Migliavacca, Eugenia, Hussain, S Farzana, Heimberger, Amy B, Desbaillets, Isabelle, Hamou, Marie-France, Rüegg, Curzio, Stupp, Roger, Delorenzi, Mauro, Hegi, Monika E

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Epigenetic silencing of HTATIP2 in glioblastoma contributes to treatment resistance by enhancing nuclear translocation of the DNA repair protein MPG von Nguyen, Thi Tham, Rajakannu, Premnath, Pham, Minh Diêu Thanh, Weman, Leo, Jucht, Alexander, Buri, Michelle C, Van Dommelen, Kristof, Hegi, Monika E

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Clinical Trial Substantiates the Predictive Value of O-6-Methylguanine-DNA Methyltransferase Promoter Methylation in Glioblastoma Patients Treated with Temozolomide von HEGI, Monika E, DISERENS, Annie-Claire, GODARD, Sophie, DIETRICH, Pierre-Yves, REGLI, Luca, OSTERMANN, Sandrine, OTTEN, Philippe, VAN MELLE, Guy, DE TRIBOLET, Nicolas, STUPP, Roger

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