Crystal structure of cholesteryl ester transfer protein reveals a long tunnel and four bound lipid molecules von Thompson, John F, Wang, Ing-Kae, Stutzman-Engwall, Kim J, Freeman, Thomas B, Chrunyk, Boris A, Hayward, Cheryl M, Ammirati, Mark J, Cong, Yang, Lloyd, David B, Subashi, Timothy A, Karam, George A, Hoth, Lise R, McGrath, Katherine M, Seddon, Andrew P, Lira, Maruja E, Mistry, Anil, Hawrylik, Steven J, Qiu, Xiayang, Geoghegan, Kieran F, Griffor, Matthew C, Hensley, Preston, Clark, Ronald W, Danley, Dennis E, Subashi, Ann K, Zhao, Honglei, Culp, Jeffrey S

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Synthesis of Quinazolin-4(3H)‑ones via Amidine N‑Arylation von Li, Bryan, Samp, Lacey, Sagal, John, Hayward, Cheryl M, Yang, Christine, Zhang, Zhijun

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Application of Biocatalytic Reductive Amination for the Synthesis of a Key Intermediate to a CDK 2/4/6 Inhibitor von Duan, Shengquan, Widlicka, Daniel W, Burns, Michael P, Kumar, Rajesh, Hotham, Ian, Desrosiers, Jean-Nicolas, Bowles, Paul, Jones, Kris N, Nicholson, Lindsay D, Buetti-Weekly, Michele T, Han, Lu, Steflik, Jeremy, Hansen, Eric, Hayward, Cheryl M, Strohmeyer, Holly, Monfette, Sébastien, Sutton, Scott C, Morris, Christopher

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Process Development of a Second Generation β‑Amyloid-Cleaving Enzyme InhibitorImproving the Robustness of a Halogen-Metal Exchange Using Continuous Stirred-Tank Reactors von Li, Bryan, Barnhart, Richard W, Dion, Amelie, Guinness, Steven, Happe, Alan, Hayward, Cheryl M, Kohrt, Jeffrey, Makowski, Teresa, Maloney, Mark, Nelson, Jade D, Nematalla, Asaad, McWilliams, J. Christopher, Peng, Zhihui, Raggon, Jeffrey, Sagal, John, Weisenburger, Gerald A, Bao, Denghui, Gonzalez, Miguel, Lu, Jiangping, McLaws, Mark D, Tao, Jian, Wu, Baolin

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Total synthesis of rapamycin via a novel titanium-mediated aldol macrocyclization reaction von Hayward, Cheryl M, Yohannes, Daniel, Danishefsky, Samuel J

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Molecular characterization of novel and selective peroxisome proliferator-activated receptor alpha agonists with robust hypolipidemic activity in vivo von Kane, Christopher D, Stevens, Kimberly A, Fischer, James E, Haghpassand, Mehrdad, Royer, Lori J, Aldinger, Charles, Landschulz, Katherine T, Zagouras, Panayiotis, Bagley, Scott W, Hada, William, Dullea, Robert, Hayward, Cheryl M, Francone, Omar L

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Process Development of a Novel Azetidinyl Ketolide Antibiotic von Li, Bryan, Magee, Thomas V, Buzon, Richard A, Widlicka, Daniel W, Bill, Dave R, Brandt, Thomas, Cao, Xiaoping, Coutant, Michael, Dou, Haijian, Granskog, Karl, Flanagan, Mark E, Hayward, Cheryl M, Li, Bin, Liu, Fengwei, Liu, Wei, Nguyen, Thuy-Trinh, Raggon, Jeffrey W, Rose, Peter, Rainville, Joseph, Reilly, Usa Datta, Shen, Yue, Sun, Jianmin, Wilcox, Glenn E

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Continuous Process for Preparing the Difluoromethylating Reagent [(DMPU) 2 Zn(CF 2 H) 2 ] and Improved Synthesis of the ICHF 2 Precursor von Monfette, Sebastien, Fang, Yuan-Qing, Bio, Matthew M., Brown, Adam R., Crouch, Ian T., Desrosiers, Jean-Nicolas, Duan, Shengquan, Hawkins, Joel M., Hayward, Cheryl M., Peperni, Nikita, Rainville, Joseph P.

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A radical chlorodifluoromethylation protocol for late-stage difluoromethylation and its application to an oncology candidate von Meng, Depei, Li, Lingchun, Brown, Adam, Desrosiers, Jean-Nicolas, Duan, Shengquan, Hayward, Cheryl M., He, Zhengbiao, Hu, Jinbo, Makowski, Teresa, Maloney, Mark, Monfette, Sébastien, Perfect, Hahdi, Piper, Jared L., Zhou, Min, Widlicka, Daniel W.

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Continuous flow aminolysis under high temperature and pressure von Li, Bryan, Bader, Scott, Guinness, Steve M., Ruggeri, Sally Gut, Hayward, Cheryl M., Hoagland, Steve, Lucas, John, Li, Ruizhi, Limburg, David, McWilliams, J. Christopher, Raggon, Jeffrey, Van Alsten, John

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Crystal structure of human squalene synthase. A key enzyme in cholesterol biosynthesis von Pandit, J, Danley, D E, Schulte, G K, Mazzalupo, S, Pauly, T A, Hayward, C M, Hamanaka, E S, Thompson, J F, Harwood, Jr, H J

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ChemInform Abstract: Synthesis of Quinazolin-4(3H)-ones via Amidine N-Arylation von Li, Bryan, Samp, Lacey, Sagal, John, Hayward, Cheryl M., Yang, Christine, Zhang, Zhijun

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Crystal Structure of Human Squalene Synthase von Pandit, Jayvardhan, Danley, Dennis E., Schulte, Gayle K., Mazzalupo, Stacy, Pauly, Thomas A., Hayward, Cheryl M., Hamanaka, Ernest S., Thompson, John F., Harwood, H. James

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An application of the Suárez reaction to the regiospecific and stereospecific synthesis of the C28-C42 segment of rapamycin von HAYWARD, C. M, FISHER, M. J, YOHANNES, D, DANISHEFSKY, S. J

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Molecular Characterization of Novel and Selective Peroxisome Proliferator-Activated Receptor α Agonists with Robust Hypolipidemic Activity in Vivo von Christopher D. Kane, Kimberly A. Stevens, James E. Fischer, Mehrdad Haghpassand, Lori J. Royer, Charles Aldinger, Katherine T. Landschulz, Panayiotis Zagouras, Scott W. Bagley, William Hada, Robert Dullea, Cheryl M. Hayward, Omar L. Francone

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An application of the suárez reaction to the regiospecific and stereospecific synthesis of the C 28-C 42 segment of rapamycin von Hayward, Cheryl M., Fisher, Matthew J., Yohannes, Daniel, Danishefsky, Samuel J.

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An application of the evans-prasad 1,3-syn diol synthesis to a stereospecific synthesis of the C10-C27 segment of rapamycin von HORVATH, R. F, LINDE, R. G, HAYWARD, C. M, JOGLAR, J, YOHANNES, D, DANISHEFSKY, S. J

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An application of the evans-prasad 1,3-syn diol synthesis to a stereospecific synthesis of the C 10-C 27 segment of rapamycin von Horvath, Raymond F., Linde, Robert G., Hayward, Cheryl M., Joglar, Jesus, Yohannes, Daniel, Danishefsky, Samuel J.

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Synthesis of pyrido [2,3-D] pyrimidin-7(8H)-ones von HAYWARD, CHERYL M, DESROSIERS, JEAN-NICOLAS, HAWKINS, JOEL MICHAEL, WIDLICKA, DANIEL WILLIAM, PERFECT, HAHDI HAKIMIOUN, BROWN, ADAM ROSS, DUAN, SHENGQUAN, MALONEY, MARK THOMAS, MONFETTE, SEBASTIEN

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PPAR compounds von HAYWARD CHERYL M, PERRY DAVID A

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