Glucokinase activity in diabetes: too much of a good thing? von Ashcroft, Frances M., Lloyd, Matthew, Haythorne, Elizabeth A.

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Diabetes causes marked inhibition of mitochondrial metabolism in pancreatic β-cells von Haythorne, Elizabeth, Rohm, Maria, van de Bunt, Martijn, Brereton, Melissa F., Tarasov, Andrei I., Blacker, Thomas S., Sachse, Gregor, Silva dos Santos, Mariana, Terron Exposito, Raul, Davis, Simon, Baba, Otto, Fischer, Roman, Duchen, Michael R., Rorsman, Patrik, MacRae, James I., Ashcroft, Frances M.

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Beta Cell Hubs Dictate Pancreatic Islet Responses to Glucose von Johnston, Natalie R., Mitchell, Ryan K., Haythorne, Elizabeth, Pessoa, Maria Paiva, Semplici, Francesca, Ferrer, Jorge, Piemonti, Lorenzo, Marchetti, Piero, Bugliani, Marco, Bosco, Domenico, Berishvili, Ekaterine, Duncanson, Philip, Watkinson, Michael, Broichhagen, Johannes, Trauner, Dirk, Rutter, Guy A., Hodson, David J.

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Altered glycolysis triggers impaired mitochondrial metabolism and mTORC1 activation in diabetic β-cells von Haythorne, Elizabeth, Lloyd, Matthew, Walsby-Tickle, John, Tarasov, Andrei I., Sandbrink, Jonas, Portillo, Idoia, Exposito, Raul Terron, Sachse, Gregor, Cyranka, Malgorzata, Rohm, Maria, Rorsman, Patrik, McCullagh, James, Ashcroft, Frances M.

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Editorial: Ion channels and transporters in diabetes and metabolic diseases von Puljung, Michael, Haythorne, Elizabeth, Rohm, Maria, Vedovato, Natascia

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Binding of sulphonylureas to plasma proteins - A KATP channel perspective von Proks, Peter, Kramer, Holger, Haythorne, Elizabeth, Ashcroft, Frances M

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The pore-forming subunit MCU of the mitochondrial Ca2+ uniporter is required for normal glucose-stimulated insulin secretion in vitro and in vivo in mice von Georgiadou, Eleni, Haythorne, Elizabeth, Dickerson, Matthew T., Lopez-Noriega, Livia, Pullen, Timothy J., da Silva Xavier, Gabriela, Davis, Samuel P. X., Martinez-Sanchez, Aida, Semplici, Francesca, Rizzuto, Rosario, McGinty, James A., French, Paul M., Cane, Matthew C., Jacobson, David A., Leclerc, Isabelle, Rutter, Guy A.

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Chronic d-serine supplementation impairs insulin secretion von Suwandhi, Lisa, Hausmann, Simone, Braun, Alexander, Gruber, Tim, Heinzmann, Silke S., Gálvez, Eric J.C., Buck, Achim, Legutko, Beata, Israel, Andreas, Feuchtinger, Annette, Haythorne, Elizabeth, Staiger, Harald, Heni, Martin, Häring, Hans-Ulrich, Schmitt-Kopplin, Philippe, Walch, Axel, Cáceres, Cristina García, Tschöp, Matthias H., Rutter, Guy A., Strowig, Till, Elsner, Martin, Ussar, Siegfried

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Phenotype of a transient neonatal diabetes point mutation (SUR1-R1183W) in mice von Sachse, Gregor, Haythorne, Elizabeth, Proks, Peter, Stewart, Michelle, Cater, Heather, Ellard, Sian, Davies, Ben, Ashcroft, Frances M

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Dysregulation of Glucagon Secretion by Hyperglycemia-Induced Sodium-Dependent Reduction of ATP Production von Knudsen, Jakob G., Hamilton, Alexander, Ramracheya, Reshma, Tarasov, Andrei I., Brereton, Melissa, Haythorne, Elizabeth, Chibalina, Margarita V., Spégel, Peter, Mulder, Hindrik, Zhang, Quan, Ashcroft, Frances M., Adam, Julie, Rorsman, Patrik

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Binding of sulphonylureas to plasma proteins - A K.sub.ATP channel perspective von Proks, Peter, Kramer, Holger, Haythorne, Elizabeth, Ashcroft, Frances M

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Local and regional control of calcium dynamics in the pancreatic islet von Rutter, Guy A., Hodson, David J., Chabosseau, Pauline, Haythorne, Elizabeth, Pullen, Timothy J., Leclerc, Isabelle

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The KCNJ11-E23K Gene Variant Hastens Diabetes Progression by Impairing Glucose-Induced Insulin Secretion von Sachse, Gregor, Haythorne, Elizabeth, Hill, Thomas, Proks, Peter, Joynson, Russell, Terrón-Expósito, Raul, Bentley, Liz, Tucker, Stephen J, Cox, Roger D, Ashcroft, Frances M

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Disallowance of Acot7 in [Beta]-Cells Is Required for Normal Glucose Tolerance and Insulin Secretion von Martinez-Sanchez, Aida, Pullen, Timothy J, Chabosseau, Pauline, Zhang, Qifeng, Haythorne, Elizabeth, Cane, Matthew C, Nguyen-Tu, Marie-Sophie, Sayers, Sophie R, Rutter, Guy A

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Disallowance of Acot7 in β-Cells Is Required for Normal Glucose Tolerance and Insulin Secretion von Martinez-Sanchez, Aida, Pullen, Timothy J, Chabosseau, Pauline, Zhang, Qifeng, Haythorne, Elizabeth, Cane, Matthew C, Nguyen-Tu, Marie-Sophie, Sayers, Sophie R, Rutter, Guy A

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343-LB: The Type 2 Diabetes-Associated Lipid Binding Protein STARD10 Controls Insulin Secretory Granule Biogenesis von CARRAT, GAELLE, HAYTHORNE, ELIZABETH, HAATAJA, LEENA, ARVAN, PETER, TOMAS, ALEJANDRA, PIUNTI, ALEXANDRA, PULLEN, TIMOTHY J., GEORGIADOU, ELENI, STYLIANIDES, THEODOROS, SALEM, VICTORIA, DISTASO, WALTER, CAKEBREAD, ANDREW, HODSON, DAVID, FUNG, ANNIE C., SESSIONS, RICHARD B., ALPY, FABIEN, KONG, ALICE P., LECLERC, ISABELLE, RUTTER, GUY A.

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Chronic exposure to KATP channel openers results in attenuated glucose sensing in hypothalamic GT1-7 neurons von Haythorne, Elizabeth, Hamilton, D. Lee, Findlay, John A., Beall, Craig, McCrimmon, Rory J., Ashford, Michael L.J.

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Chronic exposure to K ATP channel openers results in attenuated glucose sensing in hypothalamic GT1-7 neurons von Haythorne, Elizabeth, Hamilton, D Lee, Findlay, John A, Beall, Craig, McCrimmon, Rory J, Ashford, Michael L J

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Loss of electrical β-cell to δ-cell coupling underlies impaired hypoglycaemia-induced glucagon secretion in type-1 diabetes von Hill, Thomas G., Gao, Rui, Benrick, Anna, Kothegala, Lakshmi, Rorsman, Nils, Santos, Cristiano, Acreman, Samuel, Briant, Linford J., Dou, Haiqiang, Gandasi, Nikhil R., Guida, Claudia, Haythorne, Elizabeth, Wallace, Marsha, Knudsen, Jakob G., Miranda, Caroline, Tolö, Johan, Clark, Anne, Davison, Lucy, Størling, Joachim, Tarasov, Andrei, Ashcroft, Frances M., Rorsman, Patrik, Zhang, Quan

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The type 2 diabetes gene product STARD10 is a phosphoinositide-binding protein that controls insulin secretory granule biogenesis von Carrat, Gaelle R., Haythorne, Elizabeth, Tomas, Alejandra, Haataja, Leena, Müller, Andreas, Arvan, Peter, Piunti, Alexandra, Cheng, Kaiying, Huang, Mutian, Pullen, Timothy J., Georgiadou, Eleni, Stylianides, Theodoros, Amirruddin, Nur Shabrina, Salem, Victoria, Distaso, Walter, Cakebread, Andrew, Heesom, Kate J., Lewis, Philip A., Hodson, David J., Briant, Linford J., Fung, Annie C.H., Sessions, Richard B., Alpy, Fabien, Kong, Alice P.S., Benke, Peter I., Torta, Federico, Teo, Adrian Kee Keong, Leclerc, Isabelle, Solimena, Michele, Wigley, Dale B., Rutter, Guy A.

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