A Common Mechanism of Cellular Death Induced by Bactericidal Antibiotics von Kohanski, Michael A., Dwyer, Daniel J., Hayete, Boris, Lawrence, Carolyn A., Collins, James J.

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Large-scale mapping and validation of Escherichia coli transcriptional regulation from a compendium of expression profiles von Faith, Jeremiah J, Hayete, Boris, Thaden, Joshua T, Mogno, Ilaria, Wierzbowski, Jamey, Cottarel, Guillaume, Kasif, Simon, Collins, James J, Gardner, Timothy S

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A Bayesian mathematical model of motor and cognitive outcomes in Parkinson's disease von Hayete, Boris, Wuest, Diane, Laramie, Jason, McDonagh, Paul, Church, Bruce, Eberly, Shirley, Lang, Anthony, Marek, Kenneth, Runge, Karl, Shoulson, Ira, Singleton, Andrew, Tanner, Caroline, Khalil, Iya, Verma, Ajay, Ravina, Bernard

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Inferring Gene Networks for Strains of Dehalococcoides Highlights Conserved Relationships between Genes Encoding Core Catabolic and Cell-Wall Structural Proteins von Mansfeldt, Cresten B, Heavner, Gretchen W, Rowe, Annette R, Hayete, Boris, Church, Bruce W, Richardson, Ruth E

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Bayesian network analysis of panomic biological big data identifies the importance of triglyceride-rich LDL in atherosclerosis development von Voros, Szilard, Bansal, Aruna T, Barnes, Michael R, Narula, Jagat, Maurovich-Horvat, Pal, Vazquez, Gustavo, Marvasty, Idean B, Brown, Bradley O, Voros, Isaac D, Harris, William, Voros, Viktor, Dayspring, Thomas, Neff, David, Greenfield, Alex, Furchtgott, Leon, Church, Bruce, Runge, Karl, Khalil, Iya, Hayete, Boris, Lucero, Diego, Remaley, Alan T, Newton, Roger S

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446 ALTERATIONS IN GUT MICROBIAL COMPOSITION, METABOLITES, AND TRANSCRIPTIONAL ACTIVITY AMONG PARTICIPANTS WITH NONALCOHOLIC FATTY LIVER DISEASE von Kim, Hanseul, Nelson, Paul, Thompson, Kelsey N., Nguyen, Long H., Hayete, Boris, Huttenhower, Curtis

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Large-scale identification of clinical and genetic predictors of motor progression in patients with newly diagnosed Parkinson's disease: a longitudinal cohort study and validation von Latourelle, Jeanne C, Beste, Michael T, Hadzi, Tiffany C, Miller, Robert E, Oppenheim, Jacob N, Valko, Matthew P, Wuest, Diane M, Church, Bruce W, Khalil, Iya G, Hayete, Boris, Venuto, Charles S

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4 ALTERED GUT VIRAL ECOLOGY IN METABOLIC DYSFUNCTIONASSOCIATED STEATOTIC LIVER DISEASE (MASLD) von Nzabarushimana, Etienne, Kim, Hanseul, Jensen, Jordan, Shen, Jiaxian, Nelson, Paul, Thompson, Kelsey N., Chan, Andrew T., Hayete, Boris, Huttenhower, Curtis, Nguyen, Long H.

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Gyrase inhibitors induce an oxidative damage cellular death pathway in Escherichia coli von Collins, James J, Dwyer, Daniel J, Kohanski, Michael A, Hayete, Boris

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Many Microbe Microarrays Database: uniformly normalized Affymetrix compendia with structured experimental metadata von Faith, Jeremiah J, Driscoll, Michael E, Fusaro, Vincent A, Cosgrove, Elissa J, Hayete, Boris, Juhn, Frank S, Schneider, Stephen J, Gardner, Timothy S

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Systems biology and in vitro validation identifies family with sequence similarity 129 member A (FAM129A) as an asthma steroid response modulator von McGeachie, Michael J., Clemmer, George L., Hayete, Boris, Xing, Heming, Runge, Karl, Wu, Ann Chen, Jiang, Xiaofeng, Lu, Quan, Church, Bruce, Khalil, Iya, Tantisira, Kelan, Weiss, Scott

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Preclinical Validation Studies Support Causal Machine Learning Based Identification of Novel Drug Targets for High-Risk Multiple Myeloma von Bolomsky, Arnold, Gruber, Fred, Stangelberger, Kathrin, Furchtgott, Leon, Arnold, Dominik, Raut, Puja, Wuest, Diane, Runge, Karl, Khalil, Iya, Zojer, Niklas, Munshi, Nikhil, Hayete, Boris, Ludwig, Heinz

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Systems biology and in vitro validation identifies FAM129A as asthma steroid response modulator von McGeachie, Michael J, Clemmer, George L, Hayete, Boris, Xing, Heming, Runge, Karl, Wu, Ann Chen, Jiang, Xiaofeng, Lu, Quan, Church, Bruce, Khalil, Iya, Tantisira, Kelan, Weiss, Scott

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Causal modeling of CALGB 80405 (Alliance) to identify network drivers of metastatic colorectal cancer (CRC) von Das, Rahul K, Furchtgott, Leon, Meyerhardt, Jeffrey A., Nixon, Andrew B., Innocenti, Federico, Cunha, Daniel, Rich, Kelly, Lenz, Heinz-Josef, Niedzwiecki, Donna, O'Reilly, Eileen Mary, Ou, Fang-Shu, Latourelle, Jeanne, Wuest, Diane, Hayete, Boris, Khalil, Iya, Venook, Alan P.

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Investigation of Mechanisms of Response in Multiple Myeloma Via Bayesian Causal Inference: An Early Analysis of the Commpass Study Data von Gruber, Fred, Hayete, Boris, Keats, Jonathan J, McBride, Kyle, Karl, Runge, Derome, Mary, Lonial, Sagar, Khalil, Iya, Auclair, Daniel

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Bayesian Network Models of Multiple Myeloma: Drivers of High Risk and Durable Response von Gruber, Fred, Keats, Jonathan J, McBride, Kyle, Runge, Karl, Wuest, Diane, Hadzi, Tiffany, Derome, Mary, Lonial, Sagar, Khalil, Iya, Hayete, Boris, Auclair, Daniel

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Crowdsourced High-Risk Classifiers for Multiple Myeloma Patients Commonly Identify PHF19 As a Robust Progression Biomarker von Mason, Michael J, Schinke, Carolina D., Eng, Christine, Towfic, Fadi, Gruber, Fred, White, Brian S., Cui, Yi, Li, Bailiang, Yu, Thomas, Dalton, William S., Goldschmidt, Hartmut, Avet-Loiseau, Herve, Samur, Mehmet, Ortiz, Maria, Trotter, Matthew, Hayete, Boris, Dervan, Andrew, Flynt, Erin, Dai, Hongyue, Bassett, Douglas, Sonneveld, Pieter, Shain, Kenneth H., Munshi, Nikhil C., Auclair, Daniel, Hose, Dirk, Morgan, Gareth, Göke, Jonathan, Walker, Brian A, Thakurta, Anjan, Guinney, Justin

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Multiple Myeloma Drivers of High Risk and Response to Stem Cell Transplantation Identified By Causal Machine Learning: Out-of-Cohort and Experimental Validation von Furchtgott, Leon, Bolomsky, Arnold, Gruber, Fred, Samur, Mehmet Kemal, Keats, Jonathan J., Yesil, Jennifer, Stangelberger, Kathrin, Attal, Michel, Moreau, Philippe, Avet-Loiseau, Hervé, Runge, Karl, Wuest, Diane, Rich, Kelly, Khalil, Iya, Hayete, Boris, Ludwig, Heinz, Munshi, Nikhil, Auclair, Daniel

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Large-scale identification of clinical and genetic predictors of Parkinson’s disease motor progression in newly-diagnosed patients: a longitudinal cohort study and validation von Latourelle, Jeanne C., Beste, Michael T., Hadzi, Tiffany C., Miller, Robert E., Oppenheim, Jacob N., Valko, Matthew P., Wuest, Diane M., Church, Bruce W., Khalil, Iya G., Hayete, Boris, Venuto, Charles S.

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Statistical modeling of CALGB 80405 (Alliance) to identify influential factors in metastatic colorectal cancer (CRC) dependent on primary (1o) tumor side von Furchtgott, Leon, Swanson, David, Hayete, Boris, Khalil, Iya, Wuest, Diane, Rich, Kelly, Nixon, Andrew B., Niedzwiecki, Donna, Meyerhardt, Jeffrey A., O'Reilly, Eileen Mary, Ou, Fang-Shu, Lenz, Heinz-Josef, Innocenti, Federico, Venook, Alan P.

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