Combination therapy with PD-1 or PD-L1 inhibitors for cancer von Hayashi, Hidetoshi, Nakagawa, Kazuhiko

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Antitumor activity of crizotinib in lung cancers harboring a MET exon 14 alteration von Drilon, Alexander, Clark, Jeffrey W., Weiss, Jared, Ou, Sai-Hong Ignatius, Camidge, D. Ross, Solomon, Benjamin J., Otterson, Gregory A., Villaruz, Liza C., Riely, Gregory J., Heist, Rebecca S., Awad, Mark M., Shapiro, Geoffrey I., Satouchi, Miyako, Hida, Toyoaki, Hayashi, Hidetoshi, Murphy, Danielle A., Wang, Sherry C., Li, Sherry, Usari, Tiziana, Wilner, Keith D., Paik, Paul K.

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B7-H3 Negatively Modulates CTL-Mediated Cancer Immunity von Yonesaka, Kimio, Haratani, Koji, Takamura, Shiki, Sakai, Hitomi, Kato, Ryoji, Takegawa, Naoki, Takahama, Takayuki, Tanaka, Kaoru, Hayashi, Hidetoshi, Takeda, Masayuki, Kato, Sigeki, Maenishi, Osamu, Sakai, Kazuko, Chiba, Yasutaka, Okabe, Takafumi, Kudo, Keita, Hasegawa, Yoshikazu, Kaneda, Hiroyasu, Yamato, Michiko, Hirotani, Kenji, Miyazawa, Masaaki, Nishio, Kazuto, Nakagawa, Kazuhiko

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Impact of EGFR-TKI Treatment on the Tumor Immune Microenvironment in EGFR Mutation-Positive Non-Small Cell Lung Cancer von Isomoto, Kohsuke, Haratani, Koji, Hayashi, Hidetoshi, Shimizu, Shigeki, Tomida, Shuta, Niwa, Takashi, Yokoyama, Toshihide, Fukuda, Yasushi, Chiba, Yasutaka, Kato, Ryoji, Tanizaki, Junko, Tanaka, Kaoru, Takeda, Masayuki, Ogura, Takashi, Ishida, Tadashi, Ito, Akihiko, Nakagawa, Kazuhiko

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Efficacy and Safety of Patritumab Deruxtecan (HER3-DXd) in EGFR Inhibitor-Resistant, EGFR -Mutated Non-Small Cell Lung Cancer von Jänne, Pasi A, Baik, Christina, Su, Wu-Chou, Johnson, Melissa L, Hayashi, Hidetoshi, Nishio, Makoto, Kim, Dong-Wan, Koczywas, Marianna, Gold, Kathryn A, Steuer, Conor E, Murakami, Haruyasu, Yang, James Chih-Hsin, Kim, Sang-We, Vigliotti, Michele, Shi, Rong, Qi, Zhenhao, Qiu, Yang, Zhao, Lihui, Sternberg, David, Yu, Channing, Yu, Helena A

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[fam‐] trastuzumab deruxtecan, antitumor activity is dependent on HER2 expression level rather than on HER2 amplification von Takegawa, Naoki, Tsurutani, Junji, Kawakami, Hisato, Yonesaka, Kimio, Kato, Ryoji, Haratani, Koji, Hayashi, Hidetoshi, Takeda, Masayuki, Nonagase, Yoshikane, Maenishi, Osamu, Nakagawa, Kazuhiko

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Lysine-Specific Demethylase 1 (LSD1/KDM1A) Is a Novel Target Gene of c-Myc von Nagasaka, Mai, Tsuzuki, Kaori, Ozeki, Yu, Tokugawa, Muneshige, Ohoka, Nobumichi, Inoue, Yasumichi, Hayashi, Hidetoshi

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Mutational activation of the epidermal growth factor receptor down‐regulates major histocompatibility complex class I expression via the extracellular signal‐regulated kinase in no... von Watanabe, Satomi, Hayashi, Hidetoshi, Haratani, Koji, Shimizu, Shigeki, Tanizaki, Junko, Sakai, Kazuko, Kawakami, Hisato, Yonesaka, Kimio, Tsurutani, Junji, Togashi, Yosuke, Nishio, Kazuto, Ito, Akihiko, Nakagawa, Kazuhiko

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Association of immune-related adverse events with immune checkpoint inhibitor efficacy: real or imaginary? von Haratani, Koji, Hayashi, Hidetoshi, Nakagawa, Kazuhiko

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Real-World Clinical Outcomes after Genomic Profiling of Circulating Tumor DNA in Patients with Previously Treated Advanced Non-Small Cell Lung Cancer von Olsen, Steven, Liao, Jiemin, Hayashi, Hidetoshi

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Nintedanib promotes antitumour immunity and shows antitumour activity in combination with PD-1 blockade in mice: potential role of cancer-associated fibroblasts von Kato, Ryoji, Haratani, Koji, Hayashi, Hidetoshi, Sakai, Kazuko, Sakai, Hitomi, Kawakami, Hisato, Tanaka, Kaoru, Takeda, Masayuki, Yonesaka, Kimio, Nishio, Kazuto, Nakagawa, Kazuhiko

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Pseudokinase Tribbles 1 (TRB1) Negatively Regulates Tumor-Suppressor Activity of p53 through p53 Deacetylation von Miyajima, Chiharu, Inoue, Yasumichi, Hayashi, Hidetoshi

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HER3 Augmentation via Blockade of EGFR/AKT Signaling Enhances Anticancer Activity of HER3-Targeting Patritumab Deruxtecan in EGFR-Mutated Non-Small Cell Lung Cancer von Yonesaka, Kimio, Tanizaki, Junko, Maenishi, Osamu, Haratani, Koji, Kawakami, Hisato, Tanaka, Kaoru, Hayashi, Hidetoshi, Sakai, Kazuko, Chiba, Yasutaka, Tsuya, Asuka, Goto, Hiroki, Otsuka, Eri, Okida, Hiroaki, Kobayashi, Maki, Yoshimoto, Ryoto, Funabashi, Masanori, Hashimoto, Yuuri, Hirotani, Kenji, Kagari, Takashi, Nishio, Kazuto, Nakagawa, Kazuhiko

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MARIPOSA: phase 3 study of first-line amivantamab + lazertinib versus osimertinib in EGFR-mutant non-small-cell lung cancer von Cho, Byoung Chul, Felip, Enriqueta, Hayashi, Hidetoshi, Thomas, Michael, Lu, Shun, Besse, Benjamin, Sun, Tao, Martinez, Melissa, Sethi, Seema N, Shreeve, S Martin, Spira, Alexander I

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TRB1 negatively regulates gluconeogenesis by suppressing the transcriptional activity of FOXO1 von Tsuzuki, Kaori, Itoh, Yuka, Inoue, Yasumichi, Hayashi, Hidetoshi

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Suppressive effects of processed aconite root on dexamethasone-induced muscle ring finger protein-1 expression and its active ingredients von Kondo, Taishi, Ishida, Tomoaki, Ye, Ke, Muraguchi, Marin, Tanimura, Yohei, Yoshida, Masato, Ishiuchi, Kan’ichiro, Abe, Tomoki, Nikawa, Takeshi, Hagihara, Keisuke, Hayashi, Hidetoshi, Makino, Toshiaki

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First-line durvalumab plus platinum-etoposide in extensive-stage small-cell lung cancer: CASPIAN Japan subgroup analysis von Hotta, Katsuyuki, Nishio, Makoto, Saito, Haruhiro, Okamoto, Isamu, Nakahara, Yasuharu, Hayashi, Hidetoshi, Hayama, Manabu, Laud, Peter, Jiang, Haiyi, Paz-Ares, Luis, Azuma, Koichi

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Synthesis of Morita–Baylis–Hillman-fluorides using 1,1,2,2-tetrafluoroethyl-N,N-dimethylamine von Sumii, Yuji, Nagasaka, Takato, Matsuno, Ayaka, Hayashi, Hidetoshi, Mimura, Hideyuki, Kagawa, Takumi, Shibata, Norio

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Nivolumab retreatment in non-small cell lung cancer patients who responded to prior immune-checkpoint inhibitors and had ICI-free intervals (WJOG9616L) von Akamatsu, Hiroaki, Teraoka, Shunsuke, Takamori, Shinkichi, Miura, Satoru, Hayashi, Hidetoshi, Hata, Akito, Toi, Yukihiro, Shiraishi, Yoshimasa, Mamesaya, Nobuaki, Sato, Yuki, Furuya, Naoki, Oyanagi, Jun, Koh, Yasuhiro, Misumi, Toshihiro, Yamamoto, Nobuyuki, Nakagawa, Kazuhiko

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HMG-CoA Reductase Inhibitor Statins Activate the Transcriptional Activity of p53 by Regulating the Expression of TAZ von Miyajima, Chiharu, Hayakawa, Yurika, Inoue, Yasumichi, Nagasaka, Mai, Hayashi, Hidetoshi

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