Structure-Based Design and Synthesis of Novel Inhibitors Targeting HDAC8 from Schistosoma mansoni for the Treatment of Schistosomiasis von Heimburg, Tino, Chakrabarti, Alokta, Lancelot, Julien, Marek, Martin, Melesina, Jelena, Hauser, Alexander-Thomas, Shaik, Tajith B, Duclaud, Sylvie, Robaa, Dina, Erdmann, Frank, Schmidt, Matthias, Romier, Christophe, Pierce, Raymond J, Jung, Manfred, Sippl, Wolfgang

Volltext

Deep convolution neural networks based artifact suppression in under-sampled radial acquisitions of myocardial T 1 mapping images von Nezafat, Maryam, El-Rewaidy, Hossam, Kucukseymen, Selcuk, Hauser, Thomas H, Fahmy, Ahmed S

Volltext

Prevalence, Clinical Significance, and Natural History of Left Ventricular Apical Aneurysms in Hypertrophic Cardiomyopathy von MARON, Martin S, FINLEY, John J, MARTIJN BOS, J, HAUSER, Thomas H, MANNING, Warren J, HAAS, Tammy S, LESSER, John R, UDELSON, James E, ACKERMAN, Michael J, MARON, Barry J

Volltext

Diffuse myocardial fibrosis in patients with mitral valve prolapse and ventricular arrhythmia von Bui, An H, Roujol, Sébastien, Foppa, Murilo, Kissinger, Kraig V, Goddu, Beth, Hauser, Thomas H, Zimetbaum, Peter J, Ngo, Long H, Manning, Warren J, Nezafat, Reza, Delling, Francesca N

Volltext

Carbamates as Potential Prodrugs and a New Warhead for HDAC Inhibition von King, Kristina, Hauser, Alexander-Thomas, Melesina, Jelena, Sippl, Wolfgang, Jung, Manfred

Volltext

SARS-CoV-2 Omicron BA.5: Evolving tropism and evasion of potent humoral responses and resistance to clinical immunotherapeutics relative to viral variants of concern von Aggarwal, Anupriya, Akerman, Anouschka, Milogiannakis, Vanessa, Silva, Mariana Ruiz, Walker, Gregory, Stella, Alberto Ospina, Kindinger, Andrea, Angelovich, Thomas, Waring, Emily, Amatayakul-Chantler, Supavadee, Roth, Nathan, Manni, Sandro, Hauser, Thomas, Barnes, Thomas, Condylios, Anna, Yeang, Malinna, Wong, Maureen, Jean, Tyra, Foster, Charles S.P., Christ, Daniel, Hoppe, Alexandra Carey, Munier, Mee Ling, Darley, David, Churchill, Melissa, Stark, Damien J., Matthews, Gail, Rawlinson, William D., Kelleher, Anthony D., Turville, Stuart G.

Volltext

Rituximab versus Cyclophosphamide in ANCA-Associated Renal Vasculitis von Jones, Rachel B, Cohen Tervaert, Jan Willem, Hauser, Thomas, Luqmani, Raashid, Morgan, Matthew D, Peh, Chen Au, Savage, Caroline O, Segelmark, Mårten, Tesar, Vladimir, van Paassen, Pieter, Walsh, Michael, Walsh, Dorothy, Westman, Kerstin, Jayne, David R.W

Volltext

The potential for histone deacetylase (HDAC) inhibitors as cestocidal drugs von Vaca, Hugo Rolando, Celentano, Ana María, Toscanini, María Agustina, Heimburg, Tino, Ghazy, Ehab, Zeyen, Patrik, Hauser, Alexander-Thomas, Oliveira, Guilherme, Elissondo, María Celina, Jung, Manfred, Sippl, Wolfgang, Camicia, Federico, Rosenzvit, Mara Cecilia

Volltext

Early mortality in systemic vasculitis: relative contribution of adverse events and active vasculitis von Little, Mark A, Nightingale, Peter, Verburgh, C A, Hauser, Thomas, De Groot, Kirsten, Savage, Caroline, Jayne, David, Harper, Lorraine

Volltext

Effects of Environmental Conditions on Nephron Number: Modeling Maternal Disease and Epigenetic Regulation in Renal Development von Fuhrmann, Lars, Lindner, Saskia, Hauser, Alexander-Thomas, Höse, Clemens, Kretz, Oliver, Cohen, Clemens D, Lindenmeyer, Maja T, Sippl, Wolfgang, Jung, Manfred, Huber, Tobias B, Wanner, Nicola

Volltext

The Emerging Therapeutic Potential of Histone Methyltransferase and Demethylase Inhibitors von Spannhoff, Astrid, Hauser, Alexander-Thomas, Heinke, Ralf, Sippl, Wolfgang, Jung, Manfred

Volltext

Coronary CT Angiography versus Standard Evaluation in Acute Chest Pain von Hoffmann, Udo, Truong, Quynh A, Schoenfeld, David A, Chou, Eric T, Woodard, Pamela K, Nagurney, John T, Pope, J. Hector, Hauser, Thomas H, White, Charles S, Weiner, Scott G, Kalanjian, Shant, Mullins, Michael E, Mikati, Issam, Peacock, W. Frank, Zakroysky, Pearl, Hayden, Douglas, Goehler, Alexander, Lee, Hang, Gazelle, G. Scott, Wiviott, Stephen D, Fleg, Jerome L, Udelson, James E

Volltext

Structural basis for the inhibition of histone deacetylase 8 (HDAC8), a key epigenetic player in the blood fluke Schistosoma mansoni von Marek, Martin, Kannan, Srinivasaraghavan, Hauser, Alexander-Thomas, Moraes Mourão, Marina, Caby, Stéphanie, Cura, Vincent, Stolfa, Diana A, Schmidtkunz, Karin, Lancelot, Julien, Andrade, Luiza, Renaud, Jean-Paul, Oliveira, Guilherme, Sippl, Wolfgang, Jung, Manfred, Cavarelli, Jean, Pierce, Raymond J, Romier, Christophe

Volltext

Modelling the concentration of anti-SARS-CoV-2 immunoglobulin G in intravenous immunoglobulin product batches von Stinca, Sara, Barnes, Thomas W, Vogel, Peter, Meyers, Wilfried, Schulte-Pelkum, Johannes, Filchtinski, Daniel, Steller, Laura, Hauser, Thomas, Manni, Sandro, Gardiner, David F, Popik, Sharon, Roth, Nathan J, Schuetz, Patrick

Volltext

Long-term outcomes and prognostic factors for survival of patients with ANCA-associated vasculitis von Sánchez Álamo, Beatriz, Moi, Laura, Bajema, Ingeborg, Faurschou, Mikkel, Flossmann, Oliver, Hauser, Thomas, Hruskova, Zdenka, Jayne, David, Luqmani, Raashid, Mahr, Alfred, Åkesson, Anna, Westman, Kerstin

Volltext

The role of HDL- and non-HDL-related parameters in cell-cholesterol efflux capacity von Asztalos, Bela F., Hauser, Thomas H., Goldfine, Allison B., Welty, Francine K., Horvath, Katalin V., Schaefer, Ernst J.

Volltext

Right Ventricular Involvement in Hypertrophic Cardiomyopathy von Maron, Martin S., MD, Hauser, Thomas H., MD, MMSc, MPH, Dubrow, Ethan, BA, Horst, Taylor A., BA, Kissinger, Kraig V., RT, Udelson, James E., MD, Manning, Warren J., MD

Volltext

Discovery of Inhibitors of Schistosoma mansoni HDAC8 by Combining Homology Modeling, Virtual Screening, and in Vitro Validation von Kannan, Srinivasaraghavan, Melesina, Jelena, Hauser, Alexander-Thomas, Chakrabarti, Alokta, Heimburg, Tino, Schmidtkunz, Karin, Walter, Alexandra, Marek, Martin, Pierce, Raymond J, Romier, Christophe, Jung, Manfred, Sippl, Wolfgang

Volltext

Association Between a Genetic Variant Related to Glutamic Acid Metabolism and Coronary Heart Disease in Individuals With Type 2 Diabetes von Qi, Lu, Qi, Qibin, Prudente, Sabrina, Mendonca, Christine, Andreozzi, Francesco, di Pietro, Natalia, Sturma, Mariella, Novelli, Valeria, Mannino, Gaia Chiara, Formoso, Gloria, Gervino, Ernest V, Hauser, Thomas H, Muehlschlegel, Jochen D, Niewczas, Monika A, Krolewski, Andrzej S, Biolo, Gianni, Pandolfi, Assunta, Rimm, Eric, Sesti, Giorgio, Trischitta, Vincenzo, Hu, Frank, Doria, Alessandro

Volltext

BET Proteins Regulate Expression of Osr1 in Early Kidney Development von Schreiber, Janina, Liaukouskaya, Nastassia, Fuhrmann, Lars, Hauser, Alexander-Thomas, Jung, Manfred, Huber, Tobias B, Wanner, Nicola

Volltext