Dissecting fibrosis: therapeutic insights from the small-molecule toolbox von Nanthakumar, Carmel B., Hatley, Richard J. D., Lemma, Seble, Gauldie, Jack, Marshall, Richard P., Macdonald, Simon J. F.

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An αv‐RGD Integrin Inhibitor Toolbox: Drug Discovery Insight, Challenges and Opportunities von Hatley, Richard J. D., Macdonald, Simon J. F., Slack, Robert J., Le, Joelle, Ludbrook, Steven B., Lukey, Pauline T.

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How Diverse Is Medicinal Chemistry? Insights into Race, Ethnicity, Origin, Gender, and Geography von Hatley, Richard J. D, McLachlan, Steve P, Baster, Kathleen, Gelder, Lucy C, Macdonald, Simon J. F

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Writing Your Next Medicinal Chemistry Article: Journal Bibliometrics and Guiding Principles for Industrial Authors von Hatley, Richard J. D, Procopiou, Panayiotis A, McLachlan, Steven P, Westendorf, Laura E, Meanwell, Nicholas A, Ewing, William R, Macdonald, Simon J. F

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Sprinkling the pixie dust: reflections on innovation and innovators in medicinal chemistry and drug discovery von Macdonald, Simon J.F., Hatley, Richard J.D.

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Synthesis of Rhazinicine by a Metal-Catalyzed CH Bond Functionalization Strategy von Beck, Elizabeth M., Hatley, Richard, Gaunt, Matthew J.

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Synthetic approaches to N- and 4-substituted 1,4-dihydro-3(2H)-isoquinolinone derivatives von O’ Sullivan, Michael J., Hatley, Richard J.D., Wellaway, Christopher R., Bew, Sean P., Richards, Christopher J.

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Core Modifications of GSK3335103 toward Orally Bioavailable αvβ6 Inhibitors with Improved Synthetic Tractability von Hryczanek, Heather F., Barrett, John, Barrett, Tim N., Burley, Glenn A., Cookson, Rosa E., Hatley, Richard J. D., Measom, Nicholas D., Roper, James A., Rowedder, James E., Slack, Robert J., Śmieja, Connor B., Macdonald, Simon J. F.

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Core Modifications of GSK3335103 toward Orally Bioavailable α v β 6 Inhibitors with Improved Synthetic Tractability von Hryczanek, Heather F, Barrett, John, Barrett, Tim N, Burley, Glenn A, Cookson, Rosa E, Hatley, Richard J D, Measom, Nicholas D, Roper, James A, Rowedder, James E, Slack, Robert J, Śmieja, Connor B, Macdonald, Simon J F

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Mild Aerobic Oxidative Palladium (II) Catalyzed C−H Bond Functionalization:  Regioselective and Switchable C−H Alkenylation and Annulation of Pyrroles von Beck, Elizabeth M, Grimster, Neil P, Hatley, Richard, Gaunt, Matthew J

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Discovery and Development of Highly Potent and Orally Bioavailable Nonpeptidic αvβ6 Integrin Inhibitors von Procopiou, Panayiotis A., Barrett, John, Crawford, Matthew H. J., Hatley, Richard J. D., Hancock, Ashley P., Pritchard, John M., Rowedder, James E., Copley, Royston C. B., Slack, Robert J., Sollis, Steven L., Thorp, Lee R., Lippa, Rhys A., Macdonald, Simon J. F., Barrett, Tim N.

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Discovery and Development of Highly Potent and Orally Bioavailable Nonpeptidic α v β 6 Integrin Inhibitors von Procopiou, Panayiotis A, Barrett, John, Crawford, Matthew H J, Hatley, Richard J D, Hancock, Ashley P, Pritchard, John M, Rowedder, James E, Copley, Royston C B, Slack, Robert J, Sollis, Steven L, Thorp, Lee R, Lippa, Rhys A, Macdonald, Simon J F, Barrett, Tim N

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The Design of Potent, Selective and Drug‐Like RGD αvβ1 Small‐Molecule Inhibitors Derived from non‐RGD α4β1 Antagonists von Hatley, Richard J. D., Barrett, Tim N., Slack, Robert J., Watson, Morag E., Baillache, Daniel J., Gruszka, Anna, Washio, Yoshiaki, Rowedder, James E., Pogány, Peter, Pal, Sandeep, Macdonald, Simon J. F.

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Pharmacological characterisation of GSK3335103, an oral αvβ6 integrin small molecule RGD-mimetic inhibitor for the treatment of fibrotic disease von Wilkinson, Alex L., John, Alison E., Barrett, John W., Gower, E., Morrison, Valerie S., Man, Yim, Pun, K. Tao, Roper, James A., Luckett, Jeni C., Borthwick, Lee A., Barksby, Ben S., Burgoyne, Rachel A., Barnes, Rory, Fisher, Andrew J., Procopiou, Panayiotis A., Hatley, Richard J.D., Barrett, Tim N., Marshall, Richard P., Macdonald, Simon J.F., Jenkins, R. Gisli, Slack, Robert J.

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Determination of the absolute configuration of (+)- and (−)-N-CBZ-3-fluoropyrrolidine-3-methanol using vibrational circular dichroism and confirmation of stereochemistry by convers... von Procopiou, Panayiotis A., Hatley, Richard J.D., Lynn, Sean M., Copley, Royston C.B., He, Yanan, Minick, Douglas J.

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2,5-Diketopiperazines as Potent, Selective, and Orally Bioavailable Oxytocin Antagonists. 3. Synthesis, Pharmacokinetics, and in Vivo Potency von Borthwick, Alan D, Davies, Dave E, Exall, Anne M, Hatley, Richard J. D, Hughes, Jennifer A, Irving, Wendy R, Livermore, David G, Sollis, Steve L, Nerozzi, Fabrizio, Valko, Klara L, Allen, Michael J, Perren, Marion, Shabbir, Shalia S, Woollard, Patrick M, Price, Mark A

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2,5-Diketopiperazines as potent and selective oxytocin antagonists 1: identification, stereochemistry and initial SAR von Wyatt, Paul G., Allen, Michael J., Borthwick, Alan D., Davies, Dave E., Exall, Anne M., Hatley, Richard J.D., Irving, Wendy R., Livermore, David G., Miller, Neil D., Nerozzi, Fabrizio, Sollis, Steve L., Szardenings, Anna Katrin

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Formal synthesis of roseophilin von Robertson, Jeremy, Hatley, Richard J. D.

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Latonduine Analogs Restore F508del–Cystic Fibrosis Transmembrane Conductance Regulator Trafficking through the Modulation of Poly-ADP Ribose Polymerase 3 and Poly-ADP Ribose Polyme... von Carlile, Graeme W., Robert, Renaud, Matthes, Elizabeth, Yang, Qi, Solari, Roberto, Hatley, Richard, Edge, Colin M., Hanrahan, John W., Andersen, Raymond, Thomas, David Y., Birault, Véronique

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Synthesis of Rhazinicine by a Metal-Catalyzed CH Bond Functionalization Strategy von Beck, Elizabeth M., Hatley, Richard, Gaunt, Matthew J.

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