Highly selective inhibition of histone demethylases by de novo macrocyclic peptides von Kawamura, Akane, Münzel, Martin, Kojima, Tatsuya, Yapp, Clarence, Bhushan, Bhaskar, Goto, Yuki, Tumber, Anthony, Katoh, Takayuki, King, Oliver N. F., Passioura, Toby, Walport, Louise J., Hatch, Stephanie B., Madden, Sarah, Müller, Susanne, Brennan, Paul E., Chowdhury, Rasheduzzaman, Hopkinson, Richard J., Suga, Hiroaki, Schofield, Christopher J.

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Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells von Tumber, Anthony, Nuzzi, Andrea, Hookway, Edward S., Hatch, Stephanie B., Velupillai, Srikannathasan, Johansson, Catrine, Kawamura, Akane, Savitsky, Pavel, Yapp, Clarence, Szykowska, Aleksandra, Wu, Na, Bountra, Chas, Strain-Damerell, Claire, Burgess-Brown, Nicola A., Ruda, Gian Filippo, Fedorov, Oleg, Munro, Shonagh, England, Katherine S., Nowak, Radoslaw P., Schofield, Christopher J., La Thangue, Nicholas B., Pawlyn, Charlotte, Davies, Faith, Morgan, Gareth, Athanasou, Nick, Müller, Susanne, Oppermann, Udo, Brennan, Paul E.

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Differential effects of HIF2α antagonist and HIF2α silencing in renal cancer and sensitivity to repurposed drugs von Arnaiz, Esther, Miar, Ana, Bridges, Esther, Prasad, Naveen, Hatch, Stephanie B, Ebner, Daniel, Lawrie, Charles H, Harris, Adrian L

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Discovery of a Highly Selective Cell‐Active Inhibitor of the Histone Lysine Demethylases KDM2/7 von Gerken, Philip A., Wolstenhulme, Jamie R., Tumber, Anthony, Hatch, Stephanie B., Zhang, Yijia, Müller, Susanne, Chandler, Shane A., Mair, Barbara, Li, Fengling, Nijman, Sebastian M. B., Konietzny, Rebecca, Szommer, Tamas, Yapp, Clarence, Fedorov, Oleg, Benesch, Justin L. P., Vedadi, Masoud, Kessler, Benedikt M., Kawamura, Akane, Brennan, Paul E., Smith, Martin D.

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Stringent thresholds in SARS-CoV-2 IgG assays lead to under-detection of mild infections von Eyre, David W, Lumley, Sheila F, O'Donnell, Denise, Stoesser, Nicole E, Matthews, Philippa C, Howarth, Alison, Hatch, Stephanie B, Marsden, Brian D, Cox, Stuart, James, Tim, Cornall, Richard J, Stuart, David I, Screaton, Gavin, Ebner, Daniel, Crook, Derrick W, Conlon, Christopher P, Jeffery, Katie, Walker, Timothy M, Peto, Timothy E A

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Automated 96-well format high throughput colony formation assay for siRNA library screen von Hatch, Stephanie B., Prevo, Remko, Chan, Tiffany, Millar, Val, Cornelissen, Bart, Higgins, Geoff, Ebner, Daniel

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XPF protein levels determine sensitivity of malignant melanoma cells to oxaliplatin chemotherapy: Suitability as a biomarker for patient selection von Hatch, Stephanie B., Swift, Lonnie P., Caporali, Simona, Carter, Rebecca, Hill, Esme J., MacGregor, Thomas P., D'Atri, Stefania, Middleton, Mark R., McHugh, Peter J., Sharma, Ricky A.

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Differential occupational risks to healthcare workers from SARS-CoV-2 observed during a prospective observational study von Eyre, David W, Lumley, Sheila F, O'Donnell, Denise, Campbell, Mark, Sims, Elizabeth, Lawson, Elaine, Warren, Fiona, James, Tim, Cox, Stuart, Howarth, Alison, Doherty, George, Hatch, Stephanie B, Kavanagh, James, Chau, Kevin K, Fowler, Philip W, Swann, Jeremy, Volk, Denis, Yang-Turner, Fan, Stoesser, Nicole, Matthews, Philippa C, Dudareva, Maria, Davies, Timothy, Shaw, Robert H, Peto, Leon, Downs, Louise O, Vogt, Alexander, Amini, Ali, Young, Bernadette C, Drennan, Philip George, Mentzer, Alexander J, Skelly, Donal T, Karpe, Fredrik, Neville, Matt J, Andersson, Monique, Brent, Andrew J, Jones, Nicola, Martins Ferreira, Lucas, Christott, Thomas, Marsden, Brian D, Hoosdally, Sarah, Cornall, Richard, Crook, Derrick W, Stuart, David I, Screaton, Gavin, Peto, Timothy Ea, Holthof, Bruno, O'Donnell, Anne-Marie, Ebner, Daniel, Conlon, Christopher P, Jeffery, Katie, Walker, Timothy M

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E2F1 proteolysis via SCF‐cyclin F underlies synthetic lethality between cyclin F loss and Chk1 inhibition von Burdova, Kamila, Yang, Hongbin, Faedda, Roberta, Hume, Samuel, Chauhan, Jagat, Ebner, Daniel, Kessler, Benedikt M, Vendrell, Iolanda, Drewry, David H, Wells, Carrow I, Hatch, Stephanie B, Dianov, Grigory L, Buffa, Francesca M, D'Angiolella, Vincenzo

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The Kinase Chemogenomic Set (KCGS): An Open Science Resource for Kinase Vulnerability Identification von Wells, Carrow I, Al-Ali, Hassan, Andrews, David M, Asquith, Christopher R M, Axtman, Alison D, Dikic, Ivan, Ebner, Daniel, Ettmayer, Peter, Fischer, Christian, Frederiksen, Mathias, Futrell, Robert E, Gray, Nathanael S, Hatch, Stephanie B, Knapp, Stefan, Lücking, Ulrich, Michaelides, Michael, Mills, Caitlin E, Müller, Susanne, Owen, Dafydd, Picado, Alfredo, Saikatendu, Kumar S, Schröder, Martin, Stolz, Alexandra, Tellechea, Mariana, Turunen, Brandon J, Vilar, Santiago, Wang, Jinhua, Zuercher, William J, Willson, Timothy M, Drewry, David H

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CHK1 inhibition exacerbates replication stress induced by IGF blockade von Wu, Xiaoning, Seraia, Elena, Hatch, Stephanie B., Wan, Xiao, Ebner, Daniel V., Aroldi, Francesca, Jiang, Yanyan, Ryan, Anderson J., Bogenrieder, Thomas, Weyer-Czernilofsky, Ulrike, Rieunier, Guillaume, Macaulay, Valentine M.

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Targeting IGF Perturbs Global Replication through Ribonucleotide Reductase Dysfunction von Rieunier, Guillaume, Wu, Xiaoning, Harris, Letitia E, Mills, Jack V, Nandakumar, Ashwin, Colling, Laura, Seraia, Elena, Hatch, Stephanie B, Ebner, Daniel V, Folkes, Lisa K, Weyer-Czernilofsky, Ulrike, Bogenrieder, Thomas, Ryan, Anderson J, Macaulay, Valentine M

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Microsatellite Instability Testing in Colorectal Carcinoma: Choice of Markers Affects Sensitivity of Detection of Mismatch Repair–Deficient Tumors von HATCH, Stephanie B, LIGHTFOOT, Harry M, GARWACKI, Christopher P, MOORE, Dominic T, CALVE, Benjamin F, WOOSLEY, John T, SCIARROTTA, Janiece, FUNKHOUSER, William K, FARBER, Rosann A

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8‑Substituted Pyrido[3,4‑d]pyrimidin-4(3H)‑one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase Inhibitors von Bavetsias, Vassilios, Lanigan, Rachel M, Ruda, Gian Filippo, Atrash, Butrus, McLaughlin, Mark G, Tumber, Anthony, Mok, N. Yi, Le Bihan, Yann-Vaï, Dempster, Sally, Boxall, Katherine J, Jeganathan, Fiona, Hatch, Stephanie B, Savitsky, Pavel, Velupillai, Srikannathasan, Krojer, Tobias, England, Katherine S, Sejberg, Jimmy, Thai, Ching, Donovan, Adam, Pal, Akos, Scozzafava, Giuseppe, Bennett, James M, Kawamura, Akane, Johansson, Catrine, Szykowska, Aleksandra, Gileadi, Carina, Burgess-Brown, Nicola A, von Delft, Frank, Oppermann, Udo, Walters, Zoe, Shipley, Janet, Raynaud, Florence I, Westaway, Susan M, Prinjha, Rab K, Fedorov, Oleg, Burke, Rosemary, Schofield, Christopher J, Westwood, Isaac M, Bountra, Chas, Müller, Susanne, van Montfort, Rob L. M, Brennan, Paul E, Blagg, Julian

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COVID-19 vaccination, risk-compensatory behaviours, and contacts in the UK von Buckell, John, Jones, Joel, Matthews, Philippa C., Diamond, Sir Ian, Rourke, Emma, Studley, Ruth, Cook, Duncan, Walker, Ann Sarah, Pouwels, Koen B.

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Quantitative SARS-CoV-2 anti-spike responses to Pfizer–BioNTech and Oxford–AstraZeneca vaccines by previous infection status von Eyre, David W., Lumley, Sheila F., Wei, Jia, Cox, Stuart, James, Tim, Justice, Anita, Jesuthasan, Gerald, O'Donnell, Denise, Howarth, Alison, Hatch, Stephanie B., Marsden, Brian D., Jones, E. Yvonne, Stuart, David I., Ebner, Daniel, Hoosdally, Sarah, Crook, Derrick W., Peto, Tim E.A., Walker, Timothy M., Stoesser, Nicole E., Matthews, Philippa C., Pouwels, Koen B., Walker, A. Sarah, Jeffery, Katie

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SARS-CoV-2 antibody prevalence, titres and neutralising activity in an antenatal cohort, United Kingdom, 14 April to 15 June 2020 von Lumley, Sheila F, Eyre, David W, McNaughton, Anna L, Howarth, Alison, Hoosdally, Sarah, Hatch, Stephanie B, Kavanagh, James, Chau, Kevin K, Downs, Louise O, Cox, Stuart, Dunn, Laura, Justice, Anita, Wareing, Susan, Dingle, Kate, Rudkin, Justine, Auckland, Kathryn, Fyfe, Alexander, Bolton, Jai, Paton, Robert, Mentzer, Alexander J, Jeffery, Katie, Andersson, Monique I, James, Tim, Peto, Tim E A, Marsden, Brian D, Screaton, Gavin, Cornall, Richard J, Klenerman, Paul, Ebner, Daniel, Stuart, David I, Crook, Derrick W, Stoesser, Nicole, Kennedy, Stephen H, Thompson, Craig, Gupta, Sunetra, Matthews, Philippa C

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Assessing histone demethylase inhibitors in cells: lessons learned von Hatch, Stephanie B, Yapp, Clarence, Montenegro, Raquel C, Savitsky, Pavel, Gamble, Vicki, Tumber, Anthony, Ruda, Gian Filippo, Bavetsias, Vassilios, Fedorov, Oleg, Atrash, Butrus, Raynaud, Florence, Lanigan, Rachel, Carmichael, LeAnne, Tomlin, Kathy, Burke, Rosemary, Westaway, Susan M, Brown, Jack A, Prinjha, Rab K, Martinez, Elisabeth D, Oppermann, Udo, Schofield, Christopher J, Bountra, Chas, Kawamura, Akane, Blagg, Julian, Brennan, Paul E, Rossanese, Olivia, Müller, Susanne

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Homologous recombination mediates S-phase-dependent radioresistance in cells deficient in DNA polymerase eta von NICOLAY, Nils H, CARTER, Rebecca, HATCH, Stephanie B, SCHULTZ, Niklas, PREVO, Remko, MCKENNA, W. Gillies, HELLEDAY, Thomas, SHARMA, Ricky A

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Antibody Status and Incidence of SARS-CoV-2 Infection in Health Care Workers von Lumley, Sheila F, O’Donnell, Denise, Stoesser, Nicole E, Matthews, Philippa C, Howarth, Alison, Hatch, Stephanie B, Marsden, Brian D, Cox, Stuart, James, Tim, Warren, Fiona, Peck, Liam J, Ritter, Thomas G, de Toledo, Zoe, Warren, Laura, Axten, David, Cornall, Richard J, Jones, E. Yvonne, Stuart, David I, Screaton, Gavin, Ebner, Daniel, Hoosdally, Sarah, Chand, Meera, Crook, Derrick W, O’Donnell, Anne-Marie, Conlon, Christopher P, Pouwels, Koen B, Walker, A. Sarah, Peto, Tim E.A, Hopkins, Susan, Walker, Timothy M, Jeffery, Katie, Eyre, David W

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