Osteopontin mediates glioblastoma-associated macrophage infiltration and is a potential therapeutic target von Wei, Jun, Marisetty, Anantha, Schrand, Brett, Gabrusiewicz, Konrad, Hashimoto, Yuuri, Ott, Martina, Grami, Zacharia, Kong, Ling-Yuan, Ling, Xiaoyang, Caruso, Hillary, Zhou, Shouhao, Wang, Y Alan, Fuller, Gregory N, Huse, Jason, Gilboa, Eli, Kang, Nannan, Huang, Xingxu, Verhaak, Roel, Li, Shulin, Heimberger, Amy B

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A Novel HER3-Targeting Antibody-Drug Conjugate, U3-1402, Exhibits Potent Therapeutic Efficacy through the Delivery of Cytotoxic Payload by Efficient Internalization von Hashimoto, Yuuri, Koyama, Kumiko, Kamai, Yasuki, Hirotani, Kenji, Ogitani, Yusuke, Zembutsu, Akiko, Abe, Manabu, Kaneda, Yuki, Maeda, Naoyuki, Shiose, Yoshinobu, Iguchi, Takuma, Ishizaka, Tomomichi, Karibe, Tsuyoshi, Hayakawa, Ichiro, Morita, Koji, Nakada, Takashi, Nomura, Taisei, Wakita, Kenichi, Kagari, Takashi, Abe, Yuki, Murakami, Masato, Ueno, Suguru, Agatsuma, Toshinori

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HER3 Augmentation via Blockade of EGFR/AKT Signaling Enhances Anticancer Activity of HER3-Targeting Patritumab Deruxtecan in EGFR-Mutated Non-Small Cell Lung Cancer von Yonesaka, Kimio, Tanizaki, Junko, Maenishi, Osamu, Haratani, Koji, Kawakami, Hisato, Tanaka, Kaoru, Hayashi, Hidetoshi, Sakai, Kazuko, Chiba, Yasutaka, Tsuya, Asuka, Goto, Hiroki, Otsuka, Eri, Okida, Hiroaki, Kobayashi, Maki, Yoshimoto, Ryoto, Funabashi, Masanori, Hashimoto, Yuuri, Hirotani, Kenji, Kagari, Takashi, Nishio, Kazuto, Nakagawa, Kazuhiko

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MiR-138 exerts anti-glioma efficacy by targeting immune checkpoints von Wei, Jun, Nduom, Edjah K, Kong, Ling-Yuan, Hashimoto, Yuuri, Xu, Shuo, Gabrusiewicz, Konrad, Ling, Xiaoyang, Huang, Neal, Qiao, Wei, Zhou, Shouhao, Ivan, Cristina, Fuller, Greg N, Gilbert, Mark R, Overwijk, Willem, Calin, George A, Heimberger, Amy B

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Photoimmunotherapy for cancer-associated fibroblasts targeting fibroblast activation protein in human esophageal squamous cell carcinoma von Watanabe, Shinichiro, Noma, Kazuhiro, Ohara, Toshiaki, Kashima, Hajime, Sato, Hiroaki, Kato, Takuya, Urano, Shinichi, Katsube, Ryoichi, Hashimoto, Yuuri, Tazawa, Hiroshi, Kagawa, Shunsuke, Shirakawa, Yasuhiro, Kobayashi, Hisataka, Fujiwara, Toshiyoshi

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Hypoxia-Driven Mechanism of Vemurafenib Resistance in Melanoma von Qin, Yong, Roszik, Jason, Chattopadhyay, Chandrani, Hashimoto, Yuuri, Liu, Chengwen, Cooper, Zachary A, Wargo, Jennifer A, Hwu, Patrick, Ekmekcioglu, Suhendan, Grimm, Elizabeth A

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Glioblastoma-infiltrated innate immune cells resemble M0 macrophage phenotype von Gabrusiewicz, Konrad, Rodriguez, Benjamin, Wei, Jun, Hashimoto, Yuuri, Healy, Luke M, Maiti, Sourindra N, Thomas, Ginu, Zhou, Shouhao, Wang, Qianghu, Elakkad, Ahmed, Liebelt, Brandon D, Yaghi, Nasser K, Ezhilarasan, Ravesanker, Huang, Neal, Weinberg, Jeffrey S, Prabhu, Sujit S, Rao, Ganesh, Sawaya, Raymond, Langford, Lauren A, Bruner, Janet M, Fuller, Gregory N, Bar-Or, Amit, Li, Wei, Colen, Rivka R, Curran, Michael A, Bhat, Krishna P, Antel, Jack P, Cooper, Laurence J, Sulman, Erik P, Heimberger, Amy B

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Overexpression of Adenovirus E1A Reverses Transforming Growth Factor-β-induced Epithelial-mesenchymal Transition in Human Esophageal Cancer Cells von Masuda, Tomoya, Tazawa, Hiroshi, Hashimoto, Yuuri, Ieda, Takeshi, Kikuchi, Satoru, Kuroda, Shinji, Noma, Kazuhiro, Urata, Yasuo, Kagawa, Shunsuke, Fujiwara, Toshiyoshi

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Genetically engineered oncolytic adenovirus induces autophagic cell death through an E2F1-microRNA-7-epidermal growth factor receptor axis von Tazawa, Hiroshi, Yano, Shuya, Yoshida, Ryosuke, Yamasaki, Yasumoto, Sasaki, Tsuyoshi, Hashimoto, Yuuri, Kuroda, Shinji, Ouchi, Masaaki, Onishi, Teppei, Uno, Futoshi, Kagawa, Shunsuke, Urata, Yasuo, Fujiwara, Toshiyoshi

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Integrated fluorescent cytology with nano‐biologics in peritoneally disseminated gastric cancer von Watanabe, Megumi, Kagawa, Shunsuke, Kuwada, Kazuya, Hashimoto, Yuuri, Shigeyasu, Kunitoshi, Ishida, Michihiro, Sakamoto, Shuichi, Ito, Atene, Kikuchi, Satoru, Kuroda, Shinji, Kishimoto, Hiroyuki, Tomida, Shuta, Yoshida, Ryuichi, Tazawa, Hiroshi, Urata, Yasuo, Fujiwara, Toshiyoshi

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A simple biological imaging system for detecting viable human circulating tumor cells von Kojima, Toru, Hashimoto, Yuuri, Watanabe, Yuichi, Kagawa, Shunsuke, Uno, Futoshi, Kuroda, Shinji, Tazawa, Hiroshi, Kyo, Satoru, Mizuguchi, Hiroyuki, Urata, Yasuo, Tanaka, Noriaki, Fujiwara, Toshiyoshi

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Telomerase-Dependent Oncolytic Adenovirus Sensitizes Human Cancer Cells to Ionizing Radiation via Inhibition of DNA Repair Machinery von KURODA, Shinji, FUJIWARA, Toshiya, URATA, Yasuo, KAGAWA, Shunsuke, FUJIWARA, Toshiyoshi, SHIRAKAWA, Yasuhiro, YAMASAKI, Yasumoto, YANO, Shuya, UNO, Futoshi, TAZAWA, Hiroshi, HASHIMOTO, Yuuri, WATANABE, Yuichi, NOMA, Kazuhiro

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Establishment of biological and pharmacokinetic assays of telomerase‐specific replication‐selective adenovirus von Hashimoto, Yuuri, Watanabe, Yuichi, Shirakiya, Yoshiko, Uno, Futoshi, Kagawa, Shunsuke, Kawamura, Hitoshi, Nagai, Katsuyuki, Tanaka, Noriaki, Kumon, Horomi, Urata, Yasuo, Fujiwara, Toshiyoshi

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Immune checkpoint blockade as a potential therapeutic target: surveying CNS malignancies von Garber, Sarah T., Hashimoto, Yuuri, Weathers, Shiao-Pei, Xiu, Joanne, Gatalica, Zoran, Verhaak, Roel G. W., Zhou, Shouhao, Fuller, Gregory N., Khasraw, Mustafa, de Groot, John, Reddy, Sandeep K., Spetzler, David, Heimberger, Amy B.

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Glioblastoma stem cell-derived exosomes induce M2 macrophages and PD-L1 expression on human monocytes von Gabrusiewicz, Konrad, Li, Xu, Wei, Jun, Hashimoto, Yuuri, Marisetty, Anantha L., Ott, Martina, Wang, Fei, Hawke, David, Yu, John, Healy, Luke M., Hossain, Anwar, Akers, Johnny C., Maiti, Sourindra N., Yamashita, Shinji, Shimizu, Yuzaburo, Dunner, Kenneth, Zal, M. Anna, Burks, Jared K., Gumin, Joy, Nwajei, Felix, Rezavanian, Aras, Zhou, Shouhao, Rao, Ganesh, Sawaya, Raymond, Fuller, Gregory N., Huse, Jason T., Antel, Jack P., Li, Shulin, Cooper, Laurence, Sulman, Erik P., Chen, Clark, Geula, Changiz, Kalluri, Raghu, Zal, Tomasz, Heimberger, Amy B.

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Viral transduction of the HER2-extracellular domain expands trastuzumab-based photoimmunotherapy for HER2-negative breast cancer cells von Shimoyama, Kyoko, Kagawa, Shunsuke, Ishida, Michihiro, Watanabe, Shinichiro, Noma, Kazuhiro, Takehara, Kiyoto, Tazawa, Hiroshi, Hashimoto, Yuuri, Tanabe, Shunsuke, Matsuoka, Junji, Kobayashi, Hisataka, Fujiwara, Toshiyoshi

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Preclinical Evaluation of Telomerase-Specific Oncolytic Virotherapy for Human Bone and Soft Tissue Sarcomas von SASAKI, Tsuyoshi, TAZAWA, Hiroshi, MORIMOTO, Yuki, URATA, Yasuo, OZAKI, Toshifumi, FUJIWARA, Toshiyoshi, HASEI, Jo, KUNISADA, Toshiyuki, YOSHIDA, Aki, HASHIMOTO, Yuuri, YANO, Shuya, YOSHIDA, Ryosuke, UNO, Futoshi, KAGAWA, Shunsuke

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Biological Ablation of Sentinel Lymph Node Metastasis in Submucosally Invaded Early Gastrointestinal Cancer von Kikuchi, Satoru, Kishimoto, Hiroyuki, Tazawa, Hiroshi, Hashimoto, Yuuri, Kuroda, Shinji, Nishizaki, Masahiko, Nagasaka, Takeshi, Shirakawa, Yasuhiro, Kagawa, Shunsuke, Urata, Yasuo, Hoffman, Robert M, Fujiwara, Toshiyoshi

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Preclinical evaluation of synergistic effect of telomerase-specific oncolytic virotherapy and gemcitabine for human lung cancer von Liu, Dong, Kojima, Toru, Ouchi, Masaaki, Kuroda, Shinji, Watanabe, Yuichi, Hashimoto, Yuuri, Onimatsu, Hideki, Urata, Yasuo, Fujiwara, Toshiyoshi

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The hTERT promoter enhances the antitumor activity of an oncolytic adenovirus under a hypoxic microenvironment von Hashimoto, Yuuri, Tazawa, Hiroshi, Teraishi, Fuminori, Kojima, Toru, Watanabe, Yuichi, Uno, Futoshi, Yano, Shuya, Urata, Yasuo, Kagawa, Shunsuke, Fujiwara, Toshiyoshi

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