Ph-like acute lymphoblastic leukemia: a high-risk subtype in adults von Jain, Nitin, Roberts, Kathryn G., Jabbour, Elias, Patel, Keyur, Eterovic, Agda Karina, Chen, Ken, Zweidler-McKay, Patrick, Lu, Xinyan, Fawcett, Gloria, Wang, Sa A., Konoplev, Sergej, Harvey, Richard C., Chen, I-Ming, Payne-Turner, Debbie, Valentine, Marcus, Thomas, Deborah, Garcia-Manero, Guillermo, Ravandi, Farhad, Cortes, Jorge, Kornblau, Steven, O'Brien, Susan, Pierce, Sherry, Jorgensen, Jeffrey, Shaw, Kenna R.Mills, Willman, Cheryl L., Mullighan, Charles G., Kantarjian, Hagop, Konopleva, Marina

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Clinical diagnostics and treatment strategies for Philadelphia chromosome–like acute lymphoblastic leukemia von Harvey, Richard C., Tasian, Sarah K.

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Potent efficacy of combined PI3K/mTOR and JAK or ABL inhibition in murine xenograft models of Ph-like acute lymphoblastic leukemia von Tasian, Sarah K., Teachey, David T., Li, Yong, Shen, Feng, Harvey, Richard C., Chen, I-Ming, Ryan, Theresa, Vincent, Tiffaney L., Willman, Cheryl L., Perl, Alexander E., Hunger, Stephen P., Loh, Mignon L., Carroll, Martin, Grupp, Stephan A.

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Rearrangement of CRLF2 in B-progenitor- and Down syndrome-associated acute lymphoblastic leukemia von Mullighan, Charles G, Collins-Underwood, J Racquel, Phillips, Letha A A, Loudin, Michael G, Liu, Wei, Zhang, Jinghui, Ma, Jing, Coustan-Smith, Elaine, Harvey, Richard C, Willman, Cheryl L, Mikhail, Fady M, Meyer, Julia, Carroll, Andrew J, Williams, Richard T, Cheng, Jinjun, Heerema, Nyla A, Basso, Giuseppe, Pession, Andrea, Pui, Ching-Hon, Raimondi, Susana C, Hunger, Stephen P, Downing, James R, Carroll, William L, Rabin, Karen R

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Targeting JAK1/2 and mTOR in murine xenograft models of Ph-like acute lymphoblastic leukemia von Maude, Shannon L., Tasian, Sarah K., Vincent, Tiffaney, Hall, Junior W., Sheen, Cecilia, Roberts, Kathryn G., Seif, Alix E., Barrett, David M., Chen, I-Ming, Collins, J. Racquel, Mullighan, Charles G., Hunger, Stephen P., Harvey, Richard C., Willman, Cheryl L., Fridman, Jordan S., Loh, Mignon L., Grupp, Stephan A., Teachey, David T.

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Aberrant STAT5 and PI3K/mTOR pathway signaling occurs in human CRLF2-rearranged B-precursor acute lymphoblastic leukemia von Tasian, Sarah K., Doral, Michelle Y., Borowitz, Michael J., Wood, Brent L., Chen, I-Ming, Harvey, Richard C., Gastier-Foster, Julie M., Willman, Cheryl L., Hunger, Stephen P., Mullighan, Charles G., Loh, Mignon L.

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Truncating Erythropoietin Receptor Rearrangements in Acute Lymphoblastic Leukemia von Iacobucci, Ilaria, Li, Yongjin, Roberts, Kathryn G., Dobson, Stephanie M., Kim, Jaeseung C., Payne-Turner, Debbie, Harvey, Richard C., Valentine, Marcus, McCastlain, Kelly, Easton, John, Yergeau, Donald, Janke, Laura J., Shao, Ying, Chen, I-Ming L., Rusch, Michael, Zandi, Sasan, Kornblau, Steven M., Konopleva, Marina, Jabbour, Elias, Paietta, Elisabeth M., Rowe, Jacob M., Pui, Ching-Hon, Gastier-Foster, Julie, Gu, Zhaohui, Reshmi, Shalini, Loh, Mignon L., Racevskis, Janis, Tallman, Martin S., Wiernik, Peter H., Litzow, Mark R., Willman, Cheryl L., McPherson, John D., Downing, James R., Zhang, Jinghui, Dick, John E., Hunger, Stephen P., Mullighan, Charles G.

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Clinical efficacy of ruxolitinib and chemotherapy in a child with Philadelphia chromosome-like acute lymphoblastic leukemia with GOLGA5-JAK2 fusion and induction failure von Ding, Yang Y, Stern, Julie W, Jubelirer, Tracey F, Wertheim, Gerald B, Lin, Fumin, Chang, Fengqi, Gu, Zhaohui, Mullighan, Charles G, Li, Yong, Harvey, Richard C, Chen, I-Ming, Willman, Cheryl L, Hunger, Stephen P, Li, Marilyn M, Tasian, Sarah K

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JAK mutations in high-risk childhood acute lymphoblastic leukemia von Mullighan, Charles G, Zhang, Jinghui, Harvey, Richard C, Collins-Underwood, J. Racquel, Schulman, Brenda A, Phillips, Letha A, Tasian, Sarah K, Loh, Mignon L, Su, Xiaoping, Liu, Wei, Devidas, Meenakshi, Atlas, Susan R, Chen, I. Ming, Clifford, Robert J, Gerhard, Daniela S, Carroll, William L, Reaman, Gregory H, Smith, Malcolm, Downing, James R, Hunger, Stephen P, Willman, Cheryl L

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Gene expression classifiers for relapse-free survival and minimal residual disease improve risk classification and outcome prediction in pediatric B-precursor acute lymphoblastic l... von Kang, Huining, Chen, I.-Ming, Wilson, Carla S., Bedrick, Edward J., Harvey, Richard C., Atlas, Susan R., Devidas, Meenakshi, Mullighan, Charles G., Wang, Xuefei, Murphy, Maurice, Ar, Kerem, Wharton, Walker, Borowitz, Michael J., Bowman, W. Paul, Bhojwani, Deepa, Carroll, William L., Camitta, Bruce M., Reaman, Gregory H., Smith, Malcolm A., Downing, James R., Hunger, Stephen P., Willman, Cheryl L.

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Evaluation of the in vitro and in vivo efficacy of the JAK inhibitor AZD1480 against JAK-mutated acute lymphoblastic leukemia von Suryani, Santi, Bracken, Lauryn S, Harvey, Richard C, Sia, Keith C S, Carol, Hernan, Chen, I-Ming, Evans, Kathryn, Dietrich, Philipp A, Roberts, Kathryn G, Kurmasheva, Raushan T, Billups, Catherine A, Mullighan, Charles G, Willman, Cheryl L, Loh, Mignon L, Hunger, Stephen P, Houghton, Peter J, Smith, Malcolm A, Lock, Richard B

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A pediatric regimen for older adolescents and young adults with acute lymphoblastic leukemia: results of CALGB 10403 von Stock, Wendy, Luger, Selina M., Advani, Anjali S., Yin, Jun, Harvey, Richard C., Mullighan, Charles G., Willman, Cheryl L., Fulton, Noreen, Laumann, Kristina M., Malnassy, Greg, Paietta, Elisabeth, Parker, Edy, Geyer, Susan, Mrózek, Krzysztof, Bloomfield, Clara D., Sanford, Ben, Marcucci, Guido, Liedtke, Michaela, Claxton, David F., Foster, Matthew C., Bogart, Jeffrey A., Grecula, John C., Appelbaum, Frederick R., Erba, Harry, Litzow, Mark R., Tallman, Martin S., Stone, Richard M., Larson, Richard A.

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Intensified chemotherapy without SCT in infant ALL: Results from COG P9407 (Cohort 3) von Dreyer, ZoAnn E., Hilden, Joanne M., Jones, Tamekia L., Devidas, Meenakshi, Winick, Naomi J., Willman, Cheryl L., Harvey, Richard C., Chen, I-Ming, Behm, Fred G., Pullen, Jeanette, Wood, Brent L., Carroll, Andrew J., Heerema, Nyla A., Felix, Carolyn A., Robinson, Blaine, Reaman, Gregory H., Salzer, Wanda L., Hunger, Stephen P., Carroll, William L., Camitta, Bruce M.

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The genomic landscape of pediatric and young adult T-lineage acute lymphoblastic leukemia von Liu, Yu, Easton, John, Shao, Ying, Maciaszek, Jamie, Wang, Zhaoming, Wilkinson, Mark R, McCastlain, Kelly, Edmonson, Michael, Pounds, Stanley B, Shi, Lei, Zhou, Xin, Ma, Xiaotu, Sioson, Edgar, Li, Yongjin, Rusch, Michael, Gupta, Pankaj, Pei, Deqing, Cheng, Cheng, Smith, Malcolm A, Auvil, Jaime Guidry, Gerhard, Daniela S, Relling, Mary V, Winick, Naomi J, Carroll, Andrew J, Heerema, Nyla A, Raetz, Elizabeth, Devidas, Meenakshi, Willman, Cheryl L, Harvey, Richard C, Carroll, William L, Dunsmore, Kimberly P, Winter, Stuart S, Wood, Brent L, Sorrentino, Brian P, Downing, James R, Loh, Mignon L, Hunger, Stephen P, Zhang, Jinghui, Mullighan, Charles G

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The genomic landscape of pediatric acute lymphoblastic leukemia von Brady, Samuel W., Roberts, Kathryn G., Gu, Zhaohui, Shi, Lei, Pounds, Stanley, Pei, Deqing, Cheng, Cheng, Dai, Yunfeng, Devidas, Meenakshi, Qu, Chunxu, Hill, Ashley N., Payne-Turner, Debbie, Ma, Xiaotu, Iacobucci, Ilaria, Baviskar, Pradyuamna, Wei, Lei, Arunachalam, Sasi, Hagiwara, Kohei, Liu, Yanling, Flasch, Diane A., Liu, Yu, Parker, Matthew, Chen, Xiaolong, Elsayed, Abdelrahman H., Pathak, Omkar, Li, Yongjin, Fan, Yiping, Michael, J. Robert, Rusch, Michael, Wilkinson, Mark R., Foy, Scott, Hedges, Dale J., Newman, Scott, Zhou, Xin, Wang, Jian, Reilly, Colleen, Sioson, Edgar, Rice, Stephen V., Pastor Loyola, Victor, Wu, Gang, Rampersaud, Evadnie, Reshmi, Shalini C., Gastier-Foster, Julie, Guidry Auvil, Jaime M., Gesuwan, Patee, Smith, Malcolm A., Winick, Naomi, Carroll, Andrew J., Heerema, Nyla A., Harvey, Richard C., Willman, Cheryl L., Larsen, Eric, Raetz, Elizabeth A., Borowitz, Michael J., Wood, Brent L., Carroll, William L., Zweidler-McKay, Patrick A., Rabin, Karen R., Mattano, Leonard A., Maloney, Kelly W., Winter, Stuart S., Burke, Michael J., Salzer, Wanda, Dunsmore, Kimberly P., Angiolillo, Anne L., Crews, Kristine R., Downing, James R., Jeha, Sima, Pui, Ching-Hon, Evans, William E., Yang, Jun J., Relling, Mary V., Gerhard, Daniela S., Loh, Mignon L., Hunger, Stephen P., Zhang, Jinghui, Mullighan, Charles G.

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SWOG 1318: A Phase II Trial of Blinatumomab Followed by POMP Maintenance in Older Patients With Newly Diagnosed Philadelphia Chromosome–Negative B-Cell Acute Lymphoblastic Leukemia... von Advani, Anjali S, Moseley, Anna, O'Dwyer, Kristen M, Wood, Brent L, Fang, Min, Wieduwilt, Matthew J, Aldoss, Ibrahim, Park, Jae H, Klisovic, Rebecca B, Baer, Maria R, Stock, Wendy, Bhave, Rupali R, Othus, Megan, Harvey, Richard C, Willman, Cheryl L, Litzow, Mark R, Stone, Richard M, Sharon, Elad, Erba, Harry P

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Genetic Alterations Activating Kinase and Cytokine Receptor Signaling in High-Risk Acute Lymphoblastic Leukemia von Roberts, Kathryn G., Morin, Ryan D., Zhang, Jinghui, Hirst, Martin, Zhao, Yongjun, Su, Xiaoping, Chen, Shann-Ching, Payne-Turner, Debbie, Churchman, Michelle L., Harvey, Richard C., Chen, Xiang, Kasap, Corynn, Yan, Chunhua, Becksfort, Jared, Finney, Richard P., Teachey, David T., Maude, Shannon L., Tse, Kane, Moore, Richard, Jones, Steven, Mungall, Karen, Birol, Inanc, Edmonson, Michael N., Hu, Ying, Buetow, Kenneth E., Chen, I-Ming, Carroll, William L., Wei, Lei, Ma, Jing, Kleppe, Maria, Levine, Ross L., Garcia-Manero, Guillermo, Larsen, Eric, Shah, Neil P., Devidas, Meenakshi, Reaman, Gregory, Smith, Malcolm, Paugh, Steven W., Evans, William E., Grupp, Stephan A., Jeha, Sima, Pui, Ching-Hon, Gerhard, Daniela S., Downing, James R., Willman, Cheryl L., Loh, Mignon, Hunger, Stephen P., Marra, Marco A., Mullighan, Charles G.

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Genomic and outcome analyses of Ph-like ALL in NCI standard-risk patients: a report from the Children's Oncology Group von Roberts, Kathryn G., Reshmi, Shalini C., Harvey, Richard C., Chen, I-Ming, Patel, Kinnari, Stonerock, Eileen, Jenkins, Heather, Dai, Yunfeng, Valentine, Marc, Gu, Zhaohui, Zhao, Yaqi, Zhang, Jinghui, Payne-Turner, Debbie, Devidas, Meenakshi, Heerema, Nyla A., Carroll, Andrew J., Raetz, Elizabeth A., Borowitz, Michael J., Wood, Brent L., Mattano, Leonard A., Maloney, Kelly W., Carroll, William L., Loh, Mignon L., Willman, Cheryl L., Gastier-Foster, Julie M., Mullighan, Charles G., Hunger, Stephen P.

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Rise and fall of subclones from diagnosis to relapse in pediatric B-acute lymphoblastic leukaemia von Ma, Xiaotu, Edmonson, Michael, Yergeau, Donald, Muzny, Donna M., Hampton, Oliver A., Rusch, Michael, Song, Guangchun, Easton, John, Harvey, Richard C., Wheeler, David A., Ma, Jing, Doddapaneni, HarshaVardhan, Vadodaria, Bhavin, Wu, Gang, Nagahawatte, Panduka, Carroll, William L., Chen, I-Ming, Gastier-Foster, Julie M., Relling, Mary V., Smith, Malcolm A., Devidas, Meenakshi, Auvil, Jaime M. Guidry, Downing, James R., Loh, Mignon L., Willman, Cheryl L., Gerhard, Daniela S., Mullighan, Charles G., Hunger, Stephen P., Zhang, Jinghui

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Rearrangement of CRLF2 is associated with mutation of JAK kinases, alteration of IKZF1, Hispanic/Latino ethnicity, and a poor outcome in pediatric B-progenitor acute lymphoblastic... von Harvey, Richard C., Mullighan, Charles G., Chen, I-Ming, Wharton, Walker, Mikhail, Fady M., Carroll, Andrew J., Kang, Huining, Liu, Wei, Dobbin, Kevin K., Smith, Malcolm A., Carroll, William L., Devidas, Meenakshi, Bowman, W. Paul, Camitta, Bruce M., Reaman, Gregory H., Hunger, Stephen P., Downing, James R., Willman, Cheryl L.

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