No shortcuts to SARS-CoV-2 antivirals von Edwards, Aled, Hartung, Ingo V.

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Expanding Chemical Probe Space: Quality Criteria for Covalent and Degrader Probes von Hartung, Ingo V., Rudolph, Joachim, Mader, Mary M., Mulder, Monique P. C., Workman, Paul

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Rules were made to be broken von Hartung, Ingo V., Huck, Bayard R., Crespo, Alejandro

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Identification and characterization of the new generation soluble guanylate cyclase stimulator BAY‐747 designed for the treatment of resistant hypertension von Wunder, Frank, Stasch, Johannes‐Peter, Knorr, Andreas, Mondritzki, Thomas, Brockschnieder, Damian, Becker‐Pelster, Eva‐Maria, Sandner, Peter, Tinel, Hanna, Redlich, Gorden, Hartung, Ingo V., Vakalopoulos, Alexandros, Follmann, Markus

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Which Small Molecule? Selecting Chemical Probes for Use in Cancer Research and Target Validation von Mader, Mary M, Rudolph, Joachim, Hartung, Ingo V, Uehling, David, Workman, Paul, Zuercher, William

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Discovery of Molidustat (BAY 85‐3934): A Small‐Molecule Oral HIF‐Prolyl Hydroxylase (HIF‐PH) Inhibitor for the Treatment of Renal Anemia von Beck, Hartmut, Jeske, Mario, Thede, Kai, Stoll, Friederike, Flamme, Ingo, Akbaba, Metin, Ergüden, Jens‐Kerim, Karig, Gunter, Keldenich, Jörg, Oehme, Felix, Militzer, Hans‐Christian, Hartung, Ingo V., Thuss, Uwe

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New Generation of sGC Stimulators: Discovery of Imidazo[1,2‑a]pyridine Carboxamide BAY 1165747 (BAY-747), a Long-Acting Soluble Guanylate Cyclase Stimulator for the Treatment of Re... von Vakalopoulos, Alexandros, Wunder, Frank, Hartung, Ingo V., Redlich, Gorden, Jautelat, Rolf, Buchgraber, Philipp, Hassfeld, Jorma, Gromov, Alexey V., Lindner, Niels, Bierer, Donald, Gries, Jörg, Kroh, Walter, Paulsen, Holger, Mittendorf, Joachim, Lang, Dieter, Becker-Pelster, Eva, Brockschnieder, Damian, Geiss, Volker, Li, Volkhart, Straub, Alexander, Knorr, Andreas, Mondritzki, Thomas, Trübel, Hubert, Raschke, Marian, Schaefer, Martina, Thomas, Dirk, Sandner, Peter, Stasch, Johannes-Peter, Follmann, Markus

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The European Federation for Medicinal Chemistry (EFMC) Best Practice Initiative: Validating Chemical Probes von Quancard, Jean, Cox, Brian, Finsinger, Dirk, Guéret, Stéphanie M., Hartung, Ingo V., Koolman, Hannes F., Messinger, Josef, Sbardella, Gianluca, Laufer, Stefan

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A miniaturized mode-of-action profiling platform enables high throughput characterization of the molecular and cellular dynamics of EZH2 inhibition von Falkenstern, Lilia, Georgi, Victoria, Bunse, Stefanie, Badock, Volker, Husemann, Manfred, Roehn, Ulrike, Stellfeld, Timo, Fitzgerald, Mark, Ferrara, Steven, Stöckigt, Detlef, Stresemann, Carlo, Hartung, Ingo V., Fernández-Montalván, Amaury

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The Chemistry and Biology of Soluble Guanylate Cyclase Stimulators and Activators von Follmann, Markus, Griebenow, Nils, Hahn, Michael G., Hartung, Ingo, Mais, Franz-Josef, Mittendorf, Joachim, Schäfer, Martina, Schirok, Hartmut, Stasch, Johannes-Peter, Stoll, Friederike, Straub, Alexander

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Discovery and Characterization of a Highly Potent and Selective Aminopyrazoline-Based in Vivo Probe (BAY-598) for the Protein Lysine Methyltransferase SMYD2 von Eggert, Erik, Hillig, Roman C, Koehr, Silke, Stöckigt, Detlef, Weiske, Jörg, Barak, Naomi, Mowat, Jeffrey, Brumby, Thomas, Christ, Clara D, ter Laak, Antonius, Lang, Tina, Fernandez-Montalvan, Amaury E, Badock, Volker, Weinmann, Hilmar, Hartung, Ingo V, Barsyte-Lovejoy, Dalia, Szewczyk, Magdalena, Kennedy, Steven, Li, Fengling, Vedadi, Masoud, Brown, Peter J, Santhakumar, Vijayaratnam, Arrowsmith, Cheryl H, Stellfeld, Timo, Stresemann, Carlo

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Targeting the aryl hydrocarbon receptor (AhR) with BAY 2416964: a selective small molecule inhibitor for cancer immunotherapy von Kober, Christina, Roewe, Julian, Schmees, Norbert, Roese, Lars, Roehn, Ulrike, Bader, Benjamin, Stoeckigt, Detlef, Prinz, Florian, Gorjánácz, Mátyás, Roider, Helge Gottfried, Olesch, Catherine, Leder, Gabriele, Irlbacher, Horst, Lesche, Ralf, Lefranc, Julien, Oezcan-Wahlbrink, Mine, Batra, Ankita Sati, Elmadany, Nirmeen, Carretero, Rafael, Sahm, Katharina, Oezen, Iris, Cichon, Frederik, Baumann, Daniel, Sadik, Ahmed, Opitz, Christiane A, Weinmann, Hilmar, Hartung, Ingo V, Kreft, Bertolt, Offringa, Rienk, Platten, Michael, Gutcher, Ilona

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Discovery of BAY-405: An Azaindole-Based MAP4K1 Inhibitor for the Enhancement of T‑Cell Immunity against Cancer von Mowat, Jeffrey, Carretero, Rafael, Leder, Gabriele, Aiguabella Font, Nuria, Neuhaus, Roland, Berndt, Sandra, Günther, Judith, Friberg, Anders, Schäfer, Martina, Briem, Hans, Raschke, Marian, Miyatake Ondozabal, Hideki, Buchmann, Bernd, Boemer, Ulf, Kreft, Bertolt, Hartung, Ingo V., Offringa, Rienk

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Systematic Potency and Property Assessment of VHL Ligands and Implications on PROTAC Design von Krieger, Johannes, Sorrell, Fiona J., Wegener, Ansgar A., Leuthner, Birgitta, Machrouhi‐Porcher, Fouzia, Hecht, Martin, Leibrock, Eva M., Müller, Juliane E., Eisert, Jonathan, Hartung, Ingo V., Schlesiger, Sarah

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Discovery and Characterization of BAY-184: A New Potent and Selective Acylsulfonamide-Benzofuran In Vivo-Active KAT6AB Inhibitor von ter Laak, Antonius, Hillig, Roman C., Ferrara, Steven J., Korr, Daniel, Barak, Naomi, Lienau, Philip, Herbert, Simon, Fernández-Montalván, Amaury Ernesto, Neuhaus, Roland, Gorjánácz, Mátyás, Puetter, Vera, Badock, Volker, Bone, Wilhelm, Strathdee, Craig, Siegel, Franziska, Schatz, Christoph, Nowak-Reppel, Katrin, Doehr, Olaf, Gradl, Stefan, Hartung, Ingo V., Meyerson, Matthew, Bouché, Léa

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Electronic and Steric Control of Regioselectivities in Rh(I)-Catalyzed (5 + 2) Cycloadditions: Experiment and Theory von Liu, Peng, Sirois, Lauren E, Cheong, Paul Ha-Yeon, Yu, Zhi-Xiang, Hartung, Ingo V, Rieck, Heiko, Wender, Paul A, Houk, K. N

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The European Federation for Medicinal Chemistry and Chemical Biology (EFMC) Best Practice Initiative: Hit Generation von Quancard, Jean, Vulpetti, Anna, Bach, Anders, Cox, Brian, Guéret, Stéphanie M., Hartung, Ingo V., Koolman, Hannes F., Laufer, Stefan, Messinger, Josef, Sbardella, Gianluca, Craft, Russell

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The 17th EFMC Short Course on Medicinal Chemistry on Small Molecule Protein Degraders von Ciulli, Alessio, O'Connor, Suzanne, Chung, Chun‐Wa, Hartung, Ingo V., Testa, Andrea, Daniels, Danette L., Heitman, Laura H.

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Donated chemical probes for open science von Müller, Susanne, Ackloo, Suzanne, Arrowsmith, Cheryl H, Bauser, Marcus, Baryza, Jeremy L, Blagg, Julian, Böttcher, Jark, Bountra, Chas, Brown, Peter J, Bunnage, Mark E, Carter, Adrian J, Damerell, David, Dötsch, Volker, Drewry, David H, Edwards, Aled M, Edwards, James, Elkins, Jon M, Fischer, Christian, Frye, Stephen V, Gollner, Andreas, Grimshaw, Charles E, IJzerman, Adriaan, Hanke, Thomas, Hartung, Ingo V, Hitchcock, Steve, Howe, Trevor, Hughes, Terry V, Laufer, Stefan, Li, Volkhart Mj, Liras, Spiros, Marsden, Brian D, Matsui, Hisanori, Mathias, John, O'Hagan, Ronan C, Owen, Dafydd R, Pande, Vineet, Rauh, Daniel, Rosenberg, Saul H, Roth, Bryan L, Schneider, Natalie S, Scholten, Cora, Singh Saikatendu, Kumar, Simeonov, Anton, Takizawa, Masayuki, Tse, Chris, Thompson, Paul R, Treiber, Daniel K, Viana, Amélia Yi, Wells, Carrow I, Willson, Timothy M, Zuercher, William J, Knapp, Stefan, Mueller-Fahrnow, Anke

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The European Federation for Medicinal Chemistry and Chemical Biology (EFMC) Best Practice Initiative: Phenotypic Drug Discovery von Quancard, Jean, Bach, Anders, Cox, Brian, Craft, Russell, Finsinger, Dirk, Guéret, Stéphanie M., Hartung, Ingo V., Laufer, Stefan, Messinger, Josef, Sbardella, Gianluca, Koolman, Hannes F.

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