Genetic Analysis of 779 Advanced Differentiated and Anaplastic Thyroid Cancers von Pozdeyev, Nikita, Gay, Laurie M, Sokol, Ethan S, Hartmaier, Ryan, Deaver, Kelsi E, Davis, Stephanie, French, Jena D, Borre, Pierre Vanden, LaBarbera, Daniel V, Tan, Aik-Choon, Schweppe, Rebecca E, Fishbein, Lauren, Ross, Jeffrey S, Haugen, Bryan R, Bowles, Daniel W

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Recurrent Loss of NFE2L2 Exon 2 Is a Mechanism for Nrf2 Pathway Activation in Human Cancers von Goldstein, Leonard D., Lee, James, Gnad, Florian, Klijn, Christiaan, Schaub, Annalisa, Reeder, Jens, Daemen, Anneleen, Bakalarski, Corey E., Holcomb, Thomas, Shames, David S., Hartmaier, Ryan J., Chmielecki, Juliann, Seshagiri, Somasekar, Gentleman, Robert, Stokoe, David

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Candidate mechanisms of acquired resistance to first-line osimertinib in EGFR-mutated advanced non-small cell lung cancer von Chmielecki, Juliann, Gray, Jhanelle E., Cheng, Ying, Ohe, Yuichiro, Imamura, Fumio, Cho, Byoung Chul, Lin, Meng-Chih, Majem, Margarita, Shah, Riyaz, Rukazenkov, Yuri, Todd, Alexander, Markovets, Aleksandra, Barrett, J. Carl, Hartmaier, Ryan J., Ramalingam, Suresh S.

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STK11/LKB1 Mutations and PD-1 Inhibitor Resistance in KRAS -Mutant Lung Adenocarcinoma von Skoulidis, Ferdinandos, Goldberg, Michael E, Greenawalt, Danielle M, Hellmann, Matthew D, Awad, Mark M, Gainor, Justin F, Schrock, Alexa B, Hartmaier, Ryan J, Trabucco, Sally E, Gay, Laurie, Ali, Siraj M, Elvin, Julia A, Singal, Gaurav, Ross, Jeffrey S, Fabrizio, David, Szabo, Peter M, Chang, Han, Sasson, Ariella, Srinivasan, Sujaya, Kirov, Stefan, Szustakowski, Joseph, Vitazka, Patrik, Edwards, Robin, Bufill, Jose A, Sharma, Neelesh, Ou, Sai-Hong I, Peled, Nir, Spigel, David R, Rizvi, Hira, Aguilar, Elizabeth Jimenez, Carter, Brett W, Erasmus, Jeremy, Halpenny, Darragh F, Plodkowski, Andrew J, Long, Niamh M, Nishino, Mizuki, Denning, Warren L, Galan-Cobo, Ana, Hamdi, Haifa, Hirz, Taghreed, Tong, Pan, Wang, Jing, Rodriguez-Canales, Jaime, Villalobos, Pamela A, Parra, Edwin R, Kalhor, Neda, Sholl, Lynette M, Sauter, Jennifer L, Jungbluth, Achim A, Mino-Kenudson, Mari, Azimi, Roxana, Elamin, Yasir Y, Zhang, Jianjun, Leonardi, Giulia C, Jiang, Fei, Wong, Kwok-Kin, Lee, J Jack, Papadimitrakopoulou, Vassiliki A, Wistuba, Ignacio I, Miller, Vincent A, Frampton, Garrett M, Wolchok, Jedd D, Shaw, Alice T, Jänne, Pasi A, Stephens, Philip J, Rudin, Charles M, Geese, William J, Albacker, Lee A, Heymach, John V

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The genomic landscape of metastatic breast cancer: Insights from 11,000 tumors von Rinaldi, Jacob, Sokol, Ethan S, Hartmaier, Ryan J, Trabucco, Sally E, Frampton, Garrett M, Goldberg, Michael E, Albacker, Lee A, Daemen, Anneleen, Manning, Gerard

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Analysis of acquired resistance mechanisms to osimertinib in patients with EGFR-mutated advanced non-small cell lung cancer from the AURA3 trial von Chmielecki, Juliann, Mok, Tony, Wu, Yi-Long, Han, Ji-Youn, Ahn, Myung-Ju, Ramalingam, Suresh S., John, Thomas, Okamoto, Isamu, Yang, James Chih-Hsin, Shepherd, Frances A., Bulusu, Krishna C., Laus, Gianluca, Collins, Barbara, Barrett, J. Carl, Hartmaier, Ryan J., Papadimitrakopoulou, Vassiliki

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A Novel Next-Generation Sequencing Approach to Detecting Microsatellite Instability and Pan-Tumor Characterization of 1000 Microsatellite Instability–High Cases in 67,000 Patient S... von Trabucco, Sally E., Gowen, Kyle, Maund, Sophia L., Sanford, Eric, Fabrizio, David A., Hall, Michael J., Yakirevich, Evgeny, Gregg, Jeffrey P., Stephens, Phil J., Frampton, Garrett M., Hegde, Priti S., Miller, Vincent A., Ross, Jeffrey S., Hartmaier, Ryan J., Huang, Shih-Min A., Sun, James X.

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High-Throughput Genomic Profiling of Adult Solid Tumors Reveals Novel Insights into Cancer Pathogenesis von Hartmaier, Ryan J, Albacker, Lee A, Chmielecki, Juliann, Bailey, Mark, He, Jie, Goldberg, Michael E, Ramkissoon, Shakti, Suh, James, Elvin, Julia A, Chiacchia, Samuel, Frampton, Garrett M, Ross, Jeffrey S, Miller, Vincent, Stephens, Philip J, Lipson, Doron

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Actionable Activating Oncogenic ERBB2/HER2 Transmembrane and Juxtamembrane Domain Mutations von Pahuja, Kanika Bajaj, Nguyen, Thong T., Jaiswal, Bijay S., Prabhash, Kumar, Thaker, Tarjani M., Senger, Kate, Chaudhuri, Subhra, Kljavin, Noelyn M., Antony, Aju, Phalke, Sameer, Kumar, Prasanna, Mravic, Marco, Stawiski, Eric W., Vargas, Derek, Durinck, Steffen, Gupta, Ravi, Khanna-Gupta, Arati, Trabucco, Sally E., Sokol, Ethan S., Hartmaier, Ryan J., Singh, Ashish, Chougule, Anuradha, Trivedi, Vaishakhi, Dutt, Amit, Patil, Vijay, Joshi, Amit, Noronha, Vanita, Ziai, James, Banavali, Sripad D., Ramprasad, Vedam, DeGrado, William F., Bueno, Raphael, Jura, Natalia, Seshagiri, Somasekar

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Clinical impact of subclonal EGFR T790M mutations in advanced-stage EGFR-mutant non-small-cell lung cancers von Vaclova, Tereza, Grazini, Ursula, Ward, Lewis, O’Neill, Daniel, Markovets, Aleksandra, Huang, Xiangning, Chmielecki, Juliann, Hartmaier, Ryan, Thress, Kenneth S., Smith, Paul D., Barrett, J. Carl, Downward, Julian, de Bruin, Elza C.

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Sensitive Detection of Mono- and Polyclonal ESR1 Mutations in Primary Tumors, Metastatic Lesions, and Cell-Free DNA of Breast Cancer Patients von Wang, Peilu, Bahreini, Amir, Gyanchandani, Rekha, Lucas, Peter C, Hartmaier, Ryan J, Watters, Rebecca J, Jonnalagadda, Amruth R, Trejo Bittar, Humberto E, Berg, Aaron, Hamilton, Ronald L, Kurland, Brenda F, Weiss, Kurt R, Mathew, Aju, Leone, Jose Pablo, Davidson, Nancy E, Nikiforova, Marina N, Brufsky, Adam M, Ambros, Tadeu F, Stern, Andrew M, Puhalla, Shannon L, Lee, Adrian V, Oesterreich, Steffi

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Epigenomic Deconvolution of Breast Tumors Reveals Metabolic Coupling between Constituent Cell Types von Onuchic, Vitor, Hartmaier, Ryan J., Boone, David N., Samuels, Michael L., Patel, Ronak Y., White, Wendy M., Garovic, Vesna D., Oesterreich, Steffi, Roth, Matt E., Lee, Adrian V., Milosavljevic, Aleksandar

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Osimertinib + Savolitinib to Overcome Acquired MET-Mediated Resistance in Epidermal Growth Factor Receptor-Mutated, MET-Amplified Non-Small Cell Lung Cancer: TATTON von Hartmaier, Ryan J, Markovets, Aleksandra A, Ahn, Myung Ju, Sequist, Lecia V, Han, Ji-Youn, Cho, Byoung Chul, Yu, Helena A, Kim, Sang-We, Yang, James Chih-Hsin, Lee, Jong-Seok, Su, Wu-Chou, Kowalski, Dariusz M, Orlov, Sergey, Ren, Song, Frewer, Paul, Ou, Xiaoling, Cross, Darren A E, Kurian, Nisha, Cantarini, Mireille, Jänne, Pasi A

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Osimertinib plus Selumetinib in EGFR-Mutated Non-Small Cell Lung Cancer After Progression on EGFR-TKIs: A Phase Ib, Open-Label, Multicenter Trial (TATTON Part B) von Yang, James Chih-Hsin, Ohe, Yuichiro, Chiu, Chao-Hua, Ou, Xiaoling, Cantarini, Mireille, Jänne, Pasi A, Hartmaier, Ryan J, Ahn, Myung Ju

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Genomic analysis of 63,220 tumors reveals insights into tumor uniqueness and targeted cancer immunotherapy strategies von Hartmaier, Ryan J, Charo, Jehad, Fabrizio, David, Goldberg, Michael E, Albacker, Lee A, Pao, William, Chmielecki, Juliann

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Early Clearance of Plasma Epidermal Growth Factor Receptor Mutations as a Predictor of Outcome on Osimertinib in Advanced Non-Small Cell Lung Cancer; Exploratory Analysis from AURA... von Gray, Jhanelle E, Ahn, Myung-Ju, Oxnard, Geoffrey R, Shepherd, Frances A, Imamura, Fumio, Cheng, Ying, Okamoto, Isamu, Cho, Byoung Chul, Lin, Meng-Chih, Wu, Yi-Long, Majem, Margarita, Gautschi, Oliver, Boyer, Michael, Bulusu, Krishna C, Markovets, Aleksandra, Barrett, J Carl, Hodge, Rachel, McKeown, Astrid, Hartmaier, Ryan J, Chmielecki, Juliann, Papadimitrakopoulou, Vassiliki A, Ramalingam, Suresh S

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Transcriptome Characterization of Matched Primary Breast and Brain Metastatic Tumors to Detect Novel Actionable Targets von Varešlija, Damir, Priedigkeit, Nolan, Fagan, Ailís, Purcell, Siobhan, Cosgrove, Nicola, O'Halloran, Philip J, Ward, Elspeth, Cocchiglia, Sinéad, Hartmaier, Ryan, Castro, Carlos A, Zhu, Li, Tseng, George C, Lucas, Peter C, Puhalla, Shannon L, Brufsky, Adam M, Hamilton, Ronald L, Mathew, Aju, Leone, Jose P, Basudan, Ahmed, Hudson, Lance, Dwyer, Róisín, Das, Sudipto, O'Connor, Darran P, Buckley, Patrick G, Farrell, Michael, Hill, Arnold D K, Oesterreich, Steffi, Lee, Adrian V, Young, Leonie S

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Author Correction: Candidate mechanisms of acquired resistance to first-line osimertinib in EGFR-mutated advanced non-small cell lung cancer von Chmielecki, Juliann, Gray, Jhanelle E., Cheng, Ying, Ohe, Yuichiro, Imamura, Fumio, Cho, Byoung Chul, Lin, Meng-Chih, Majem, Margarita, Shah, Riyaz, Rukazenkov, Yuri, Todd, Alexander, Markovets, Aleksandra, Barrett, J. Carl, Hartmaier, Ryan J., Ramalingam, Suresh S.

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ERBB3 and IGF1R Signaling Are Required for Nrf2-Dependent Growth in KEAP1-Mutant Lung Cancer von Vartanian, Steffan, Lee, James, Klijn, Christiaan, Gnad, Florian, Bagniewska, Maria, Schaefer, Gabriele, Zhang, Donglu, Tan, Jenille, Watson, Sara A, Liu, Liling, Chen, Honglin, Liang, Yuxin, Watanabe, Colin, Cuellar, Trinna, Kan, David, Hartmaier, Ryan J, Lau, Ted, Costa, Michael R, Martin, Scott E, Merchant, Mark, Haley, Benjamin, Stokoe, David

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A phase Ib study of the highly selective MET-TKI savolitinib plus gefitinib in patients with EGFR-mutated, MET-amplified advanced non-small-cell lung cancer von Yang, Jin-Ji, Fang, Jian, Shu, Yong-Qian, Chang, Jian-Hua, Chen, Gong-Yan, He, Jian Xing, Li, Wei, Liu, Xiao-Qing, Yang, Nong, Zhou, Caicun, Huang, Jian An, Frigault, Melanie M., Hartmaier, Ryan, Ahmed, Ghada F., Egile, Coumaran, Morgan, Shethah, Verheijen, Remy B., Mellemgaard, Anders, Yang, Liu, Wu, Yi-Long

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