Therapeutic Targeting of Oncogenic K-Ras by a Covalent Catalytic Site Inhibitor von Lim, Sang Min, Westover, Kenneth D., Ficarro, Scott B., Harrison, Rane A., Choi, Hwan Geun, Pacold, Michael E., Carrasco, Martin, Hunter, John, Kim, Nam Doo, Xie, Ting, Sim, Taebo, Jänne, Pasi A., Meyerson, Matthew, Marto, Jarrod A., Engen, John R., Gray, Nathanael S.

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ExoSTING, an extracellular vesicle loaded with STING agonists, promotes tumor immune surveillance von Jang, Su Chul, Economides, Kyriakos D., Moniz, Raymond J., Sia, Chang Ling, Lewis, Nuruddeen, McCoy, Christine, Zi, Tong, Zhang, Kelvin, Harrison, Rane A., Lim, Joanne, Dey, Joyoti, Grenley, Marc, Kirwin, Katherine, Ross, Nikki L., Bourdeau, Raymond, Villiger-Oberbek, Agata, Estes, Scott, Xu, Ke, Sanchez-Salazar, Jorge, Dooley, Kevin, Dahlberg, William K., Williams, Douglas E., Sathyanarayanan, Sriram

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Conformational insight into multi-protein signaling assemblies by hydrogen–deuterium exchange mass spectrometry von Harrison, Rane A, Engen, John R

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A versatile platform for generating engineered extracellular vesicles with defined therapeutic properties von Dooley, Kevin, McConnell, Russell E., Xu, Ke, Lewis, Nuruddeen D., Haupt, Sonya, Youniss, Madeleine R., Martin, Shelly, Sia, Chang Ling, McCoy, Christine, Moniz, Raymond J., Burenkova, Olga, Sanchez-Salazar, Jorge, Jang, Su Chul, Choi, Bryan, Harrison, Rane A., Houde, Damian, Burzyn, Dalia, Leng, Charan, Kirwin, Katherine, Ross, Nikki L., Finn, Jonathan D., Gaidukov, Leonid, Economides, Kyriakos D., Estes, Scott, Thornton, James E., Kulman, John D., Sathyanarayanan, Sriram, Williams, Douglas E.

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Modulating the strength of hydrogen bond acceptors to achieve low Caco2 efflux for oral bioavailability of PARP inhibitors blocking centrosome clustering von Gu, Chungang, Lamb, Michelle L., Johannes, Jeffrey W., Sylvester, Mark A., Eisman, Mark S., Harrison, Rane A., Hu, Haiqing, Kazmirski, Steven, Mikule, Keith, Peng, Bo, Su, Nancy, Wang, Wenxian, Ye, Qing, Zheng, Xiaolan, Lyne, Paul D., Scott, David A.

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Structural Dynamics in Ras and Related Proteins upon Nucleotide Switching von Harrison, Rane A., Lu, Jia, Carrasco, Martin, Hunter, John, Manandhar, Anuj, Gondi, Sudershan, Westover, Kenneth D., Engen, John R.

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KRAS G12C Drug Development: Discrimination between Switch II Pocket Configurations Using Hydrogen/Deuterium-Exchange Mass Spectrometry von Lu, Jia, Harrison, Rane A., Li, Lianbo, Zeng, Mei, Gondi, Sudershan, Scott, David, Gray, Nathanael S., Engen, John R., Westover, Kenneth D.

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Therapeutic Targeting of Oncogenic K-Ras by a Covalent Catalytic Site Inhibitor von Lim, Sang Min, Westover, Kenneth D., Ficarro, Scott B., Harrison, Rane A., Choi, Hwan Geun, Pacold, Michael E., Carrasco, Martin, Hunter, John, Kim, Nam Doo, Xie, Ting, Sim, Taebo, Jänne, Pasi A., Meyerson, Matthew, Marto, Jarrod A., Engen, John R., Gray, Nathanael S.

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KRAS G12C Drug Development: Discrimination between Switch II Pocket Configurations Using Hydrogen/Deuterium-Exchange Mass Spectrometry von Lu, Jia, Harrison, Rane A., Li, Lianbo, Zeng, Mei, Gondi, Sudershan, Scott, David, Gray, Nathanael S., Engen, John R., Westover, Kenneth D.

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Abstract 944: exoSTING: An engineered exosome therapeutic that selectively delivers STING agonist to the tumor resident antigen-presenting cells resulting in improved tumor antigen... von Jang, Su Chul, Moniz, Raymond J., Sia, Chang Ling, Harrison, Rane A., Houde, Damian, Ross, Nikki, Xu, Ke, Lewis, Nuruddeen, Bourdeau, Raymond, McCoy, Christine, Zi, Tong, Villiger-Oberbek, Agata, Estes, Scott, Sanchez-Salazar, Jorge, Dooley, Kevin, Dahlberg, William K., Sathyanarayanan, Sriram, Economides, Kyriakos D.

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PREPARATION OF THERAPEUTIC EXOSOMES USING MEMBRANE PROTEINS von HOUDE DAMIAN, HAUPT SONYA, ROSS NIKKI, XU KE, HARRISON RANE A, WILLIAMS DOUGLAS E, KULMAN JOHN D, MCCONNELL RUSSELL E, DOOLEY KEVIN P

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조작된 세포외 소포체 및 이의 용도 von HAUPT SONYA, XU KE, HOUDE DAMIAN J, YOUNISS MADELEINE, HARRISON RANE A, WILLIAMS DOUGLAS E, KULMAN JOHN D, MCCONNELL RUSSELL E, DOOLEY KEVIN P

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PREPARATION OF THERAPEUTIC EXOSOMES USING MEMBRANE PROTEINS von XU, Ke, ROSS, Nikki, MCCONNELL, Russell E, KULMAN, John D, HOUDE, Damian J, HAUPT, Sonya, DOOLEY, Kevin P, HARRISON, Rane A, WILLIAMS, Douglas E

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COMPOSITIONS OF ENGINEERED EXOSOMES AND METHODS OF LOADING LUMINAL EXOSOMES PAY-LOADS von XU, Ke, MCCONNELL, Russell E, KULMAN, John D, HOUDE, Damian J, HAUPT, Sonya, DOOLEY, Kevin P, YOUNISS, Madeleine, HARRISON, Rane A, WILLIAMS, Douglas E

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STING-작용제를 포함하는 세포외 소수포 von ECONOMIDES KYRIAKOS, LEWIS NURUDDEEN D, SATHYANARAYANAN SRIRAM, SIA CHANG LING, JANG SU CHUL, HARRISON RANE A, WILLIAMS DOUGLAS E, MONIZ RAYMOND J

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Preparation of therapeutic exosomes using membrane proteins von McConnell, Russell E, Ross, Nikki, Dooley, Kevin P, Houde, Damian J, Williams, Douglas E, Harrison, Rane A, Kulman, John D, Xu, Ke, Haupt, Sonya

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조작된 엑소좀의 조성물 및 내강 엑소좀 페이로드의 로딩 방법 von HAUPT SONYA, XU KE, HOUDE DAMIAN J, YOUNISS MADELEINE, HARRISON RANE A, WILLIAMS DOUGLAS E, KULMAN JOHN D, MCCONNELL RUSSELL E, DOOLEY KEVIN P

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막 단백질을 사용한 치료용 엑소좀의 제조 von HOUDE DAMIAN, HAUPT SONYA, ROSS NIKKI, XU KE, HARRISON RANE A, WILLIAMS DOUGLAS E, KULMAN JOHN D, MCCONNELL RUSSELL E, DOOLEY KEVIN P

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ENGINEERED EXTRACELLULAR VESICLES AND USES THEREOF von XU, Ke, MCCONNELL, Russell E, KULMAN, John D, HOUDE, Damian J, HAUPT, Sonya, DOOLEY, Kevin P, YOUNISS, Madeleine, HARRISON, Rane A, WILLIAMS, Douglas E

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ENGINEERED EXTRACELLULAR VESICLES AND USES THEREOF von XU, Ke, MCCONNELL, Russell E, KULMAN, John D, HOUDE, Damian J, HAUPT, Sonya, DOOLEY, Kevin P, YOUNISS, Madeleine, HARRISON, Rane A, WILLIAMS, Douglas E

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