Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate von Harlan, John E, Hajduk, Philip J, Yoon, Ho Sup, Fesik, Stephen W

Volltext

Structure and ligand recognition of the phosphotyrosine binding domain of Shc von Zhou, Ming-Ming, Ravichandran, Kodimangalam S, Olejniczak, Edward T, Petros, Andrew M, Meadows, Robert P, Sattler, Michael, Harlan, John E, Wade, Warren S, Burakoff, Steven J, Fesik, Stephen W

Volltext

X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death von MUCHMORE, S. W, SATTLER, M, NG, S.-C, FESIK, S. W, LIANG, H, MEADOWS, R. P, HARLAN, J. E, YOON, H. S, NETTESHEIM, D, CHANG, B. S, THOMPSON, C. B, WONG, S.-L

Volltext

Evidence for a requirement for both phospholipid and phosphotyrosine binding via the Shc phosphotyrosine-binding domain in vivo von Ravichandran, Kodimangalam S., Zhou, Ming-Ming, Pratt, Joanne C., Harlan, John E., Walk, Scott F., Fesik, Stephen W., Burakoff, Steven J.

Volltext

NMR Structure and Mutagenesis of the N-Terminal Dbl Homology Domain of the Nucleotide Exchange Factor Trio von Liu, Xiaohong, Wang, Hong, Eberstadt, Matthias, Schnuchel, Arndt, Olejniczak, Edward T, Meadows, Robert P, Schkeryantz, Jeff M, Janowick, David A, Harlan, John E, Harris, Edith A.S, Staunton, Donald E, Fesik, Stephen W

Volltext

Driving affinity selection by centrifugal force von Harlan, J E, Egan, D A, Ladror, U S, Snyder, S, Tang, M I, Buko, A, Holzman, T F

Volltext

Drosophila seizure disorders： genetic suppression of seizure susceptibility von Saras, Arunesh, Simon, Laura E., Brawer, Harlan J., Price, Richard E., Tanouye, Mark A.

Volltext

Structural Characterization of the Interaction between a Pleckstrin Homology Domain and Phosphatidylinositol 4,5-Bisphosphate von Harlan, John E, Yoon, Ho Sup, Hajduk, Philip J, Fesik, Stephen W

Volltext

The BH3 domain of Bcl-x(S) is required for inhibition of the antiapoptotic function of Bcl-x(L) von Chang, B S, Kelekar, A, Harris, M H, Harlan, J E, Fesik, S W, Thompson, C B

Volltext

Binding Affinities of Tyrosine-phosphorylated Peptides to the COOH-terminal SH2 and NH2-terminal Phosphotyrosine Binding Domains of Shc (∗) von Zhou, Ming-Ming, Harlan, John E., Wade, Warren S., Crosby, Seth, Ravichandran, Kodimangalam S., Burakoff, Steven J., Fesik, Stephen W.

Volltext

Structure of Bcl-x-Bak peptide complex: recognition between regulators of apoptosis von Sattler, Michael, Nettesheim, David, Meadows, Robert P, Harlan, John E, Eberstadt, Matthias, Yoon, Ho Sup, Shuker, Suzanne B, Chang, Brian S, Minn, Andy J, Thompson, Craig B, Fesik, Stephen W

Volltext

Calibration of Size-Exclusion Chromatography: Use of a Double Gaussian Distribution Function to Describe Pore Sizes von Harlan, J.E., Picot, D., Loll, P.J., Garavito, R.M.

Volltext

Bad is a BH3 domain-containing protein that forms an inactivating dimer with Bcl-XL von Kelekar, Ameeta, Chang, Brian S., Harlan, John E., Fesik, Stephen W., Thompson, Craig B.

Volltext

Structure of Bcl-xL-Bak peptide complex : Recognition between regulators of apoptosis von SATTLER, M, LIANG, H, THOMPSON, C. B, FESIK, S. W, NETTESHEIM, D, MEADOWS, R. P, HARLAN, J. E, EBERSTADT, M, HO SUP YOON, SHUKER, S. B, CHANG, B. S, MINN, A. J

Volltext

Discovery of Potent Inhibitors of Dihydroneopterin Aldolase Using CrystaLEAD High-Throughput X-ray Crystallographic Screening and Structure-Directed Lead Optimization von Sanders, William J, Nienaber, Vicki L, Lerner, Claude G, McCall, J. Owen, Merrick, Sean M, Swanson, Susan J, Harlan, John E, Stoll, Vincent S, Stamper, Geoffrey F, Betz, Stephen F, Condroski, Kevin R, Meadows, Robert P, Severin, Jean M, Walter, Karl A, Magdalinos, Peter, Jakob, Clarissa G, Wagner, Rolf, Beutel, Bruce A

Volltext

Structure of MurF from Streptococcus pneumoniae co‐crystallized with a small molecule inhibitor exhibits interdomain closure von Longenecker, Kenton L., Stamper, Geoffrey F., Hajduk, Philip J., Fry, Elizabeth H., Jakob, Clarissa G., Harlan, John E., Edalji, Rohinton, Bartley, Diane M., Walter, Karl A., Solomon, Larry R., Holzman, Thomas F., Gu, Yu Gui, Lerner, Claude G., Beutel, Bruce A., Stoll, Vincent S.

Volltext

NMR Studies of the Anti-Apoptotic Protein Bcl-xL in Micelles von Losonczi, Judit A, Olejniczak, Edward T, Betz, Stephen F, Harlan, John E, Mack, Jamey, Fesik, Stephen W

Volltext

Rubella susceptibility in sixth graders: effectiveness of current immunization practice von Lawless, M R, Abramson, J S, Harlan, J E, Kelsey, D S

Volltext

A highly potent and selective farnesyltransferase inhibitor ABT-100 in preclinical studies von Gu, Wen-Zhen, Joseph, Ingrid, Wang, Yi-Chun, Frost, David, Sullivan, Gerard M, Wang, Le, Lin, Nan-Horng, Cohen, Jerry, Stoll, Vincent S, Jakob, Clarissa G, Muchmore, Steven W, Harlan, John E, Holzman, Tom, Walten, Karl A, Ladror, Uri S, Anderson, Mark G, Kroeger, Paul, Rodriguez, Luis E, Jarvis, Kenneth P, Ferguson, Debra, Marsh, Kennan, Ng, Shichung, Rosenberg, Saul H, Sham, Hing L, Zhang, Haiying

Volltext

The BH3 Domain of Bcl-x sub(S) Is Required for Inhibition of the Antiapoptotic Function of Bcl-x sub(L) von Chang, B S, Kelekar, A, Harris, M H, Harlan, JE, Fesik, S W, Thompson, C B

Volltext