Snowshoe-ski that allows user to glide downhill as well as climb von HARKIN JAMES B

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Integrated tumor identification and automated scoring minimizes pathologist involvement and provides new insights to key biomarkers in breast cancer von Bankhead, Peter, Fernández, José A, McArt, Darragh G, Boyle, David P, Li, Gerald, Loughrey, Maurice B, Irwin, Gareth W, Harkin, D Paul, James, Jacqueline A, McQuaid, Stephen, Salto-Tellez, Manuel, Hamilton, Peter W

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Identification and Validation of an Anthracycline/ Cyclophosphamide-Based Chemotherapy Response Assay in Breast Cancer von MULLIGAN, Jude M, HILL, Laura A, QUINN, Jennifer E, LINDOR, Noralane M, MULLAN, Paul B, JAMES, Colin R, WALKER, Steven M, KERR, Peter, JAMES, Jacqueline, DAVISON, Timothy S, PROUTSKI, Vitali, SALTO-TELLEZ, Manuel, DEHARO, Steve, JOHNSTON, Patrick G, COUCH, Fergus J, HARKIN, D. Paul, KENNEDY, Richard D, IRWIN, Gareth, BOYLE, David, KEATING, Katherine E, RAJI, Olaide Y, MCDYER, Fionnuala A, O'BRIEN, Eamonn, BYLESJO, Max

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Validation of a Metastatic Assay using biopsies to improve risk stratification in patients with prostate cancer treated with radical radiation therapy von Jain, S., Lyons, C.A., Walker, S.M., McQuaid, S., Hynes, S.O., Mitchell, D.M., Pang, B., Logan, G.E., McCavigan, A.M., O’Rourke, D., McArt, D.G., McDade, S.S., Mills, I.G., Prise, K.M., Knight, L.A., Steele, C.J., Medlow, P.W., Berge, V., Katz, B., Loblaw, D.A., Harkin, D.P., James, J.A., O'sullivan, J.M., Kennedy, R.D., Waugh, D.J.

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Transformer-based biomarker prediction from colorectal cancer histology: A large-scale multicentric study von Wagner, Sophia J., Reisenbüchler, Daniel, West, Nicholas P., Niehues, Jan Moritz, Zhu, Jiefu, Foersch, Sebastian, Veldhuizen, Gregory Patrick, Quirke, Philip, Grabsch, Heike I., van den Brandt, Piet A., Hutchins, Gordon G.A., Richman, Susan D., Yuan, Tanwei, Langer, Rupert, Jenniskens, Josien C.A., Offermans, Kelly, Mueller, Wolfram, Gray, Richard, Gruber, Stephen B., Greenson, Joel K., Rennert, Gad, Bonner, Joseph D., Schmolze, Daniel, Jonnagaddala, Jitendra, Hawkins, Nicholas J., Ward, Robyn L., Morton, Dion, Seymour, Matthew, Magill, Laura, Nowak, Marta, Hay, Jennifer, Koelzer, Viktor H., Church, David N., Church, David, Domingo, Enric, Edwards, Joanne, Glimelius, Bengt, Gogenur, Ismail, Harkin, Andrea, Hay, Jen, Iveson, Timothy, Jaeger, Emma, Kelly, Caroline, Kerr, Rachel, Maka, Noori, Morgan, Hannah, Oien, Karin, Orange, Clare, Palles, Claire, Roxburgh, Campbell, Sansom, Owen, Saunders, Mark, Tomlinson, Ian, Matek, Christian, Geppert, Carol, Peng, Chaolong, Zhi, Cheng, Ouyang, Xiaoming, James, Jacqueline A., Loughrey, Maurice B., Salto-Tellez, Manuel, Brenner, Hermann, Hoffmeister, Michael, Truhn, Daniel, Schnabel, Julia A., Boxberg, Melanie, Peng, Tingying, Kather, Jakob Nikolas

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BRCA1 mRNA Expression Levels Predict for Overall Survival in Ovarian Cancer after Chemotherapy von Quinn, Jennifer E, James, Colin R, Stewart, Gail E, Mulligan, Jude M, White, Patricia, Chang, Gary K F, Mullan, Paul B, Johnston, Patrick G, Wilson, Richard H, Harkin, D Paul

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The prognostic significance of the aberrant extremes of p53 immunophenotypes in breast cancer von Boyle, David P, McArt, Darragh G, Irwin, Gareth, Wilhelm-Benartzi, Charlotte S, Lioe, Tong F, Sebastian, Elena, McQuaid, Stephen, Hamilton, Peter W, James, Jacqueline A, Mullan, Paul B, Catherwood, Mark A, Harkin, D Paul, Salto-Tellez, Manuel

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BRCA1, a Potential Predictive Biomarker in the Treatment of Breast Cancer von James, Colin R., Quinn, Jennifer E., Mullan, Paul B., Johnston, Patrick G., Harkin, D. Paul

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Induction of GADD45 and JNK/SAPK-Dependent Apoptosis following Inducible Expression of BRCA1 von Harkin, D.Paul, Bean, James M, Miklos, David, Song, Young-Han, Truong, Vivi B, Englert, Christoph, Christians, Fred C, Ellisen, Leif W, Maheswaran, Shyamala, Oliner, Jonathan D, Haber, Daniel A

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Molecular Basis for Estrogen Receptor α Deficiency in BRCA1-Linked Breast Cancer von Hosey, Alison M., Gorski, Julia J., Murray, Margaret M., Quinn, Jennifer E., Chung, Wen Y., Stewart, Gail E., James, Colin R., Farragher, Susan M., Mulligan, Jude M., Scott, Alistair N., Dervan, Peter A., Johnston, Patrick G., Couch, Fergus J., Daly, Peter A., Kay, Elaine, McCann, Amanda, Mullan, Paul B., Harkin, D. Paul

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Immune microenvironment modulation following neoadjuvant therapy for oesophageal adenocarcinoma: a translational analysis of the DEBIOC clinical trial von Scanlon, E., Lavery, A., Albraikat, M., Stevenson, L., Kennedy, C., Byrne, R., Walker, A., Mullan-Young, B., McManus, D.T., Virdee, P.S., Elhussein, L., Turbitt, J., Collinson, D., Miedzybrodzka, Z., Van Schaeybroeck, S., McQuaid, S., James, J.A., Craig, S.G., Blayney, J.K., Petty, R.D., Harkin, D.P., Kennedy, R.D., Eatock, M.M., Middleton, M.R., Thomas, A., Turkington, R.C.

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BRCA1 and c-Myc associate to transcriptionally repress psoriasin, a DNA damage-inducible gene von Kennedy, Richard D, Gorski, Julia J, Quinn, Jennifer E, Stewart, Gail E, James, Colin R, Moore, Stephen, Mulligan, Karl, Emberley, Ethan D, Lioe, Tong F, Morrison, Patrick J, Mullan, Paul B, Reid, George, Johnston, Patrick G, Watson, Peter H, Harkin, D Paul

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Delirium is prevalent in older hospital inpatients and associated with adverse outcomes: results of a prospective multi-centre study on World Delirium Awareness Day von Kumbun, Gary, Treml, Jonathan, Moseley, Alice, Reid, James, Furmedge, Daniel, Mohammedseid-Nurhussien, Awolkhier, Welch, Carly, Briggs, Laura, Macharouthu, Ajay, Horton, Robbie, Moore, Emily, Layton, Georgia R, Holmes, Elizabeth, Brown, Harriet, Dove, James, Valentine, Janine, Glasser, Martin, Kearney, Matthew, Pyc, Wioletta, Page, Valerie, Nicholls, Isabelle, Tinson, Guy, Hunt, Clare, Stratton, Emma, McCulloch, Alison, Abdelbadiee, Sherif, Yunus, Aayenah, Jatti, Puja, Cox, Natalie, Williamson, Katherine, Mills, Sam, Cheah, Khai Lee, Hindley, Esther, Chuter, Charlotte, Le Poideven, Andre, Harkin, Teresa, Taylor, Joanne, Pang, Norman, Iqbal, Shoaib, Jackson, Peter, Naish, George, Kuek, Dorothy, Chapman, George E, Mahida, Rahul, McClelland, Sarah B, Nandra, Taran, Greaves, Isabel, Lonsdale-Eccles, Elizabeth, Bultynck, Celine, Nagumantry, Shonit, Morrow, Olivia, Lewis, Anna, Wu, Edward, Abdullah, Saad, Chilton, Angharad, Porter, Lucy, Marshall, John, Sen, Michael, Ibanichuka, Jacqueline, Rickard, Frances, Jones, Howell, Studley, Mark, Hornsby, Alex, Adam, Muhammad, Todd, Oliver, Critchlow, Tamsin, Darko, Sandra, Swietoslawski, Adam, Currie, Hannah, Bygate, Rachael, Lee, Tammy, Foster, Kate, Velusamy, Karthika, Bei, Zhao Xiao, Evans, Olivia, Bowden, Helen, Annamalai, Arunkumar, Thake, Miriam, Deacon, Elizabeth, Prasad, Vishnu, Parkinson, Megan, Rose, Emily, Jones, Laura, Stapley, Simon, Mayor, Kara, Moore, Kirsty, A-Odame, Paapa, Kirrane, Kim, Subhan, Zahid, Ni Lochlainn, Mary, Bahsoon, Farrah, Chourot, Christian, Cohen, Sam, Krishan, Anjli, McCormack, Roisin, Wheeler, Alice, McQuillan, Alex, Aamir, Ayesha, Tan, Felicia, Nashed, Nader

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NF-κB is a critical mediator of BRCA1-induced chemoresistance von Harte, M T, Gorski, J J, Savage, K I, Purcell, J W, Barros, E M, Burn, P M, McFarlane, C, Mullan, P B, Kennedy, R D, Perkins, N D, Harkin, D P

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Molecular classification of non-invasive breast lesions for personalised therapy and chemoprevention von Buckley, Niamh, Boyle, David, McArt, Darragh, Irwin, Gareth, Harkin, D Paul, Lioe, Tong, McQuaid, Stephen, James, Jacqueline A, Maxwell, Perry, Hamilton, Peter, Mullan, Paul B, Salto-Tellez, Manuel

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Immune activation by DNA damage predicts response to chemotherapy and survival in oesophageal adenocarcinoma von Turkington, Richard C, Knight, Laura A, Blayney, Jaine K, Secrier, Maria, Douglas, Rosalie, Parkes, Eileen E, Sutton, Eilis K, Stevenson, Leanne, McManus, Damian, Halliday, Sophia, McCavigan, Andrena M, Logan, Gemma E, Walker, Steven M, Steele, Christopher J, Perner, Juliane, Bornschein, Jan, MacRae, Shona, Miremadi, Ahmad, McCarron, Eamon, McQuaid, Stephen, Arthur, Kenneth, James, Jacqueline A, Eatock, Martin M, O’Neill, Robert, Noble, Fergus, Underwood, Timothy J, Harkin, D Paul, Salto-Tellez, Manuel, Fitzgerald, Rebecca C, Kennedy, Richard D

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JAK/STAT3 represents a therapeutic target for colorectal cancer patients with stromal-rich tumors von Pennel, Kathryn A F, Hatthakarnkul, Phimmada, Wood, Colin S, Lian, Guang-Yu, Al-Badran, Sara S F, Quinn, Jean A, Legrini, Assya, Inthagard, Jitwadee, Alexander, Peter G, van Wyk, Hester, Kurniawan, Ahmad, Hashmi, Umar, Gillespie, Michael A, Mills, Megan, Ammar, Aula, Hay, Jennifer, Andersen, Ditte, Nixon, Colin, Rebus, Selma, Chang, David K, Kelly, Caroline, Harkin, Andrea, Graham, Janet, Church, David, Tomlinson, Ian, Saunders, Mark, Iveson, Tim, Lannagan, Tamsin R M, Jackstadt, Rene, Maka, Noori, Horgan, Paul G, Roxburgh, Campbell S D, Sansom, Owen J, McMillan, Donald C, Steele, Colin W, Jamieson, Nigel B, Park, James H, Roseweir, Antonia K, Edwards, Joanne

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BRCA1 transcriptionally regulates genes associated with the basal-like phenotype in breast cancer von Gorski, Julia J, James, Colin R, Quinn, Jennifer E, Stewart, Gail E, Staunton, Kieran Crosbie, Buckley, Niamh E, McDyer, Fionnuala A, Kennedy, Richard D, Wilson, Richard H, Mullan, Paul B, Harkin, D. Paul

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Assessment of Progression-Free Survival as a Surrogate End Point of Overall Survival in First-Line Treatment of Ovarian Cancer: A Systematic Review and Meta-analysis von Paoletti, Xavier, Lewsley, Liz-Anne, Daniele, Gennaro, Cook, Adrian, Yanaihara, Nozomu, Tinker, Anna, Kristensen, Gunnar, Ottevanger, Petronella B, Aravantinos, Gerasimos, Miller, Austin, Boere, Ingrid A, Fruscio, Robert, Reyners, Anna K L, Pujade-Lauraine, Eric, Harkin, Andrea, Pignata, Sandro, Kagimura, Tatsuo, Welch, Stephen, Paul, James, Karamouza, Eleni, Glasspool, Rosalind M

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TBX2 represses CST6 resulting in uncontrolled legumain activity to sustain breast cancer proliferation: a novel cancer-selective target pathway with therapeutic opportunities von D'Costa, Zenobia C, Higgins, Catherine, Ong, Chee Wee, Irwin, Gareth W, Boyle, David, McArt, Darragh G, McCloskey, Karen, Buckley, Niamh E, Crawford, Nyree T, Thiagarajan, Lalitha, Murray, James T, Kennedy, Richard D, Mulligan, Karl A, Harkin, D Paul, Waugh, David J J, Scott, Chris J, Salto-Tellez, Manuel, Williams, Richard, Mullan, Paul B

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