Temporal regulation of EGF signalling networks by the scaffold protein Shc1 von Zheng, Yong, Zhang, Cunjie, Croucher, David R., Soliman, Mohamed A., St-Denis, Nicole, Pasculescu, Adrian, Taylor, Lorne, Tate, Stephen A., Hardy, W. Rod, Colwill, Karen, Dai, Anna Yue, Bagshaw, Rick, Dennis, James W., Gingras, Anne-Claude, Daly, Roger J., Pawson, Tony

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ShcA Adaptor Protein Promotes Nephrin Endocytosis and Is Upregulated in Proteinuric Nephropathies von Martin, Claire E, Petersen, Kelly A, Aoudjit, Lamine, Tilak, Manali, Eremina, Vera, Hardy, W Rod, Quaggin, Susan E, Takano, Tomoko, Jones, Nina

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Homotypic and heterotypic immune responses to Omicron variant in immunocompromised patients in diverse clinical settings von Ferreira, Victor H., Solera, Javier T., Hu, Queenie, Hall, Victoria G., Arbol, Berta G., Rod Hardy, W., Samson, Reuben, Marinelli, Tina, Ierullo, Matthew, Virk, Avneet Kaur, Kurtesi, Alexandra, Mavandadnejad, Faranak, Majchrzak-Kita, Beata, Kulasingam, Vathany, Gingras, Anne-Claude, Kumar, Deepali, Humar, Atul

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Accelerated waning of immunity to SARS-CoV-2 mRNA vaccines in patients with immune-mediated inflammatory diseases von Dayam, Roya M, Law, Jaclyn C, Goetgebuer, Rogier L, Chao, Gary Yc, Abe, Kento T, Sutton, Mitchell, Finkelstein, Naomi, Stempak, Joanne M, Pereira, Daniel, Croitoru, David, Acheampong, Lily, Rizwan, Saima, Rymaszewski, Klaudia, Milgrom, Raquel, Ganatra, Darshini, Batista, Nathalia V, Girard, Melanie, Lau, Irene, Law, Ryan, Cheung, Michelle W, Rathod, Bhavisha, Kitaygorodsky, Julia, Samson, Reuben, Hu, Queenie, Hardy, W Rod, Haroon, Nigil, Inman, Robert D, Piguet, Vincent, Chandran, Vinod, Silverberg, Mark S, Gingras, Anne-Claude, Watts, Tania H

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Omicron variant neutralizing antibodies following BNT162b2 BA.4/5 versus mRNA-1273 BA.1 bivalent vaccination in patients with end-stage kidney disease von Yau, Kevin, Kurtesi, Alexandra, Qi, Freda, Delgado-Brand, Melanie, Tursun, Tulunay R., Hu, Queenie, Dhruve, Miten, Kandel, Christopher, Enilama, Omosomi, Levin, Adeera, Jiang, Yidi, Hardy, W. Rod, Yuen, Darren A., Perl, Jeffrey, Chan, Christopher T., Leis, Jerome A., Oliver, Matthew J., Colwill, Karen, Gingras, Anne-Claude, Hladunewich, Michelle A.

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Preclinical evaluation of a SARS-CoV-2 mRNA vaccine PTX-COVID19-B von Liu, Jun, Budylowski, Patrick, Samson, Reuben, Griffin, Bryan D, Babuadze, Giorgi, Rathod, Bhavisha, Colwill, Karen, Abioye, Jumai A, Schwartz, Jordan A, Law, Ryan, Yip, Lily, Ahn, Sang Kyun, Chau, Serena, Naghibosadat, Maedeh, Arita, Yuko, Hu, Queenie, Yue, Feng Yun, Banerjee, Arinjay, Hardy, W Rod, Mossman, Karen, Mubareka, Samira, Kozak, Robert A, Pollanen, Michael S, Martin Orozco, Natalia, Gingras, Anne-Claude, Marcusson, Eric G, Ostrowski, Mario A

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Screening for PTB Domain Binding Partners and Ligand Specificity Using Proteome-Derived NPXY Peptide Arrays von Smith, Matthew J., Hardy, W. Rod, Murphy, James M., Jones, Nina, Pawson, Tony

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An Embryonic Stem Cell-Specific NuRD Complex Functions through Interaction with WDR5 von Ee, Ly-Sha, McCannell, Kurtis N., Tang, Yang, Fernandes, Nancy, Hardy, W. Rod, Green, Michael R., Chu, Feixia, Fazzio, Thomas G.

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Combinatorial ShcA Docking Interactions Support Diversity in Tissue Morphogenesis von Hardy, W. Rod, Li, Lingying, Wang, Zhi, Sedy, Jiri, Fawcett, James, Frank, Eric, Kucera, Jan, Pawson, Tony

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The ShcA PTB Domain Functions as a Biological Sensor of Phosphotyrosine Signaling during Breast Cancer Progression von AHN, Ryuhjin, SABOURIN, Valerie, SIEGEL, Peter M, PAWSON, Tony, URSINI-SIEGEL, Josie, HA, Jacqueline R, CORY, Sean, MARIC, Gordana, YOUNG KYUEN IM, HARDY, W. Rod, HONG ZHAO, PARK, Morag, HALLETT, Michael

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The adaptor protein Grb2 is not essential for the establishment of the glomerular filtration barrier von Bisson, Nicolas, Ruston, Julie, Jeansson, Marie, Vanderlaan, Rachel, Hardy, W Rod, Du, Jianmei, Hussein, Samer M, Coward, Richard J, Quaggin, Susan E, Pawson, Tony

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Differential serum neutralisation of omicron sublineages in patients receiving prophylaxis with tixagevimab–cilgavimab von Solera, Javier T, Arbol, Berta G, Ferreira, Victor H, Kurtesi, Alexandra, Hu, Queenie, Ierullo, Matthew, Valverde-Zuniga, Adriana, Raslan, Ismail, Nasir, Asma, Grizales, Clara, Hardy, W Rod, Kulasingam, Vathany, Gingras, Anne-Claude, Humar, Atul, Kumar, Deepali

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Analysis of a Shc Family Adaptor Protein, ShcD/Shc4, That Associates with Muscle-Specific Kinase von Jones, Nina, Hardy, W. Rod, Friese, Matthew B., Jorgensen, Claus, Smith, Matthew J., Woody, Neil M., Burden, Steven J., Pawson, Tony

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The PTB domain of ShcA couples receptor activation to the cytoskeletal regulator IQGAP1 von Smith, Matthew J, Hardy, W Rod, Li, Guang-Yao, Goudreault, Marilyn, Hersch, Steven, Metalnikov, Pavel, Starostine, Andrei, Pawson, Tony, Ikura, Mitsuhiko

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Omicron BA.4/5 Neutralization and T-Cell Responses in Organ Transplant Recipients After Booster Messenger RNA Vaccine: A Multicenter Cohort Study von Ferreira, Victor H, Ierullo, Matthew, Mavandadnejad, Faranak, Kurtesi, Alexandra, Hu, Queenie, Hardy, W Rod, Hall, Victoria G, Pinzon, Natalia, Yotis, Demitra, Gingras, Anne-Claude, Belga, Sara, Shalhoub, Sarah, Hébert, Marie-Josée, Humar, Atul, Kabbani, Dima, Kumar, Deepali

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ShcA signalling is essential for tumour progression in mouse models of human breast cancer von Ursini-Siegel, Josie, Hardy, W Rod, Zuo, Dongmei, Lam, Sonya H L, Sanguin-Gendreau, Virginie, Cardiff, Robert D, Pawson, Tony, Muller, William J

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Distinct Phosphotyrosine-dependent Functions of the ShcA Adaptor Protein Are Required for Transforming Growth Factor β (TGFβ)-induced Breast Cancer Cell Migration, Invasion, and Me... von Northey, Jason J., Dong, Zhifeng, Ngan, Elaine, Kaplan, Andrew, Hardy, W. Rod, Pawson, Tony, Siegel, Peter M.

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Modification of the Creator recombination system for proteomics applications--improved expression by addition of splice sites von Colwill, Karen, Wells, Clark D, Elder, Kelly, Goudreault, Marilyn, Hersi, Kadija, Kulkarni, Sarang, Hardy, W Rod, Pawson, Tony, Morin, Gregg B

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UNC-129 regulates the balance between UNC-40 dependent and independent UNC-5 signaling pathways von MacNeil, Lesley T, Hardy, W Rod, Pawson, Tony, Wrana, Jeffrey L, Culotti, Joseph G

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Modulation of Erbb2 signaling during development: a threshold level of Erbb2 signaling is required for development von Chan, Richard, Hardy, W Rod, Dankort, David, Laing, Michael A, Muller, William J

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