Ratiometric dosing of anticancer drug combinations: Controlling drug ratios after systemic administration regulates therapeutic activity in tumor-bearing mice von Mayer, Lawrence D, Harasym, Troy O, Tardi, Paul G, Harasym, Natashia L, Shew, Clifford R, Johnstone, Sharon A, Ramsay, Euan C, Bally, Marcel B, Janoff, Andrew S

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Modulating the Therapeutic Activity of Nanoparticle Delivered Paclitaxel by Manipulating the Hydrophobicity of Prodrug Conjugates von Ansell, Steven M, Johnstone, Sharon A, Tardi, Paul G, Lo, Lily, Xie, Sherwin, Shu, Yu, Harasym, Troy O, Harasym, Natashia L, Williams, Laura, Bermudes, David, Liboiron, Barry D, Saad, Walid, Prud’homme, Robert K, Mayer, Lawrence D

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Treatment of colorectal cancer using a combination of liposomal irinotecan (Irinophore C™) and 5-fluorouracil von Hare, Jennifer I, Neijzen, Robert W, Anantha, Malathi, Dos Santos, Nancy, Harasym, Natashia, Webb, Murray S, Allen, Theresa M, Bally, Marcel B, Waterhouse, Dawn N

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In vivo maintenance of synergistic cytarabine:daunorubicin ratios greatly enhances therapeutic efficacy von Tardi, Paul, Johnstone, Sharon, Harasym, Natashia, Xie, Sherwin, Harasym, Troy, Zisman, Natalia, Harvie, Pierrot, Bermudes, David, Mayer, Lawrence

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Development of a weak-base docetaxel derivative that can be loaded into lipid nanoparticles von Zhigaltsev, Igor V., Winters, Geoff, Srinivasulu, Masuna, Crawford, Jason, Wong, Matthew, Amankwa, Lawrence, Waterhouse, Dawn, Masin, Dana, Webb, Murray, Harasym, Natashia, Heller, Lindsay, Bally, Marcel B., Ciufolini, Marco A., Cullis, Pieter R., Maurer, Norbert

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Coencapsulation of irinotecan and floxuridine into low cholesterol-containing liposomes that coordinate drug release in vivo von Tardi, Paul G., Gallagher, Ryan C., Johnstone, Sharon, Harasym, Natashia, Webb, Murray, Bally, Marcel B., Mayer, Lawrence D.

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Liposomal Irinotecan von Messerer, Corrie Lynn, Ramsay, Euan C., Waterhouse, Dawn, Ng, Rebecca, Simms, Eva-Maria, Harasym, Natashia, Tardi, Paul, Mayer, Lawrence D., Bally, Marcel B.

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Irinophore C™, a lipid nanoparticle formulation of irinotecan, abrogates the gastrointestinal effects of irinotecan in a rat model of clinical toxicities von Waterhouse, Dawn N., Sutherland, Brent W., Santos, Nancy Dos, Masin, Dana, Osooly, Maryam, Strutt, Dita, Ostlund, Christina, Anantha, Malathi, Harasym, Natashia, Manisali, Irina, Wehbe, Mohamed, Bally, Marcel B., Webb, Murray S.

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Treatment of Colorectal Cancer Using a Combination of Liposomal Irinotecan von Hare, Jennifer I, Neijzen, Robert W, Anantha, Malathi, Dos Santos, Nancy, Harasym, Natashia, Webb, Murray S, Allen, Theresa M, Bally, Marcel B, Waterhouse, Dawn N

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Liposomal irinotecan: Formulation development and therapeutic assessment in murine xenograft models of colorectal cancer von MESSERER, Corrie Lynn, RAMSAY, Euan C, WATERHOUSE, Dawn, NG, Rebecca, SIMMS, Eva-Maria, HARASYM, Natashia, TARDI, Paul, MAYER, Lawrence D, BALLY, Marcel B

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In vitro and in vivo characterization of a combination chemotherapy formulation consisting of vinorelbine and phosphatidylserine von Webb, Murray S., Johnstone, Sharon, Morris, Tara J., Kennedy, Allison, Gallagher, Ryan, Harasym, Natashia, Harasym, Troy, Shew, Clifford R., Tardi, Paul, Dragowska, Wieslawa H., Mayer, Lawrence D., Bally, Marcel B.

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In vitro and in vivo characterization of a combination chemotherapy formulation consisting of vinorelbine and phosphatidylserine: Drug delivery: a Canadian perspective von WEBB, Murray S, JOHNSTONE, Sharon, MAYER, Lawrence D, BALLY, Marcel B, MORRIS, Tara J, KENNEDY, Allison, GALLAGHER, Ryan, HARASYM, Natashia, HARASYM, Troy, SHEW, Clifford R, TARDI, Paul, DRAGOWSKA, Wieslawa H

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O-288 Anti-metastatic and anti-tumor efficacy of G3139, a Bcl-2 antisense oligonucleotide, as single agent or in combination with vinorelbine, in murine orthotopic and ectopic xeno... von Hu, Yanping, Yan, Hong, Masin, Dana, Ng, Rebecca, Tan, Sophia, Harasym, Natashia, Bally, Marcel, Mayer, Lawrence

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