Mouse models of nonalcoholic steatohepatitis in preclinical drug development von Hansen, Henrik H., Feigh, Michael, Veidal, Sanne S., Rigbolt, Kristoffer T., Vrang, Niels, Fosgerau, Keld

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Metabolic and gut microbiome changes following GLP-1 or dual GLP-1/GLP-2 receptor agonist treatment in diet-induced obese mice von Madsen, Mette Simone Aae, Holm, Jacob Bak, Pallejà, Albert, Wismann, Pernille, Fabricius, Katrine, Rigbolt, Kristoffer, Mikkelsen, Martin, Sommer, Morten, Jelsing, Jacob, Nielsen, Henrik Bjørn, Vrang, Niels, Hansen, Henrik H.

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Metabolic and hepatic effects of liraglutide, obeticholic acid and elafibranor in diet-induced obese mouse models of biopsy-confirmed nonalcoholic steatohepatitis von Tølbøl, Kirstine S, Kristiansen, Maria Nb, Hansen, Henrik H, Veidal, Sanne S, Rigbolt, Kristoffer Tg, Gillum, Matthew P, Jelsing, Jacob, Vrang, Niels, Feigh, Michael

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The GLP-1 receptor agonist liraglutide reduces pathology-specific tau phosphorylation and improves motor function in a transgenic hTauP301L mouse model of tauopathy von Hansen, Henrik H, Barkholt, Pernille, Fabricius, Katrine, Jelsing, Jacob, Terwel, Dick, Pyke, Charles, Knudsen, Lotte Bjerre, Vrang, Niels

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Towards a standard diet-induced and biopsy-confirmed mouse model of non-alcoholic steatohepatitis: Impact of dietary fat source von Boland, Michelle L, Oró, Denise, Tølbøl, Kirstine S, Thrane, Sebastian T, Nielsen, Jens Christian, Cohen, Taylor S, Tabor, David E, Fernandes, Fiona, Tovchigrechko, Andrey, Veidal, Sanne S, Warrener, Paul, Sellman, Bret R, Jelsing, Jacob, Feigh, Michael, Vrang, Niels, Trevaskis, James L, Hansen, Henrik H

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Therapeutic effects of lisinopril and empagliflozin in a mouse model of hypertension-accelerated diabetic kidney disease von Østergaard, Mette V., Secher, Thomas, Christensen, Michael, Salinas, Casper Gravesen, Roostalu, Urmas, Skytte, Jacob Lercke, Rune, Ida, Hansen, Henrik H., Jelsing, Jacob, Vrang, Niels, Fink, Lisbeth N.

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Semaglutide reduces tumor burden in the GAN diet-induced obese and biopsy-confirmed mouse model of NASH-HCC with advanced fibrosis von Hansen, Henrik H., Pors, Susanne, Andersen, Maja W., Vyberg, Mogens, Nøhr-Meldgaard, Jacob, Nielsen, Malte Hasle, Oró, Denise, Madsen, Martin Rønn, Lewinska, Monika, Møllerhøj, Mathias B., Madsen, Andreas Nygaard, Feigh, Michael

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Human translatability of the GAN diet-induced obese mouse model of non-alcoholic steatohepatitis von Hansen, Henrik H, Ægidius, Helene M, Oró, Denise, Evers, Simon S, Heebøll, Sara, Eriksen, Peter Lykke, Thomsen, Karen Louise, Bengtsson, Anja, Veidal, Sanne S, Feigh, Michel, Suppli, Malte P, Knop, Filip K, Grønbæk, Henning, Miranda, Diego, Trevaskis, James L, Vrang, Niels, Jelsing, Jacob, Rigbolt, Kristoffer T G

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Long-Term Treatment with Liraglutide, a Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist, Has No Effect on β-Amyloid Plaque Load in Two Transgenic APP/PS1 Mouse Models of Alzheimer... von Hansen, Henrik H, Fabricius, Katrine, Barkholt, Pernille, Kongsbak-Wismann, Pernille, Schlumberger, Chantal, Jelsing, Jacob, Terwel, Dick, Termont, Annelies, Pyke, Charles, Knudsen, Lotte Bjerre, Vrang, Niels

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Identification and Metabolic Profiling of a Novel Human Gut-derived LEAP2 Fragment von Hagemann, Christoffer A, Zhang, Chen, Hansen, Henrik H, Jorsal, Tina, Rigbolt, Kristoffer T G, Madsen, Martin R, Bergmann, Natasha C, Heimbürger, Sebastian M N, Falkenhahn, Mechthilde, Theis, Stefan, Breitschopf, Kristin, Holm, Stephanie, Hedegaard, Morten A, Christensen, Mikkel B, Vilsbøll, Tina, Holst, Birgitte, Vrang, Niels, Jelsing, Jacob, Knop, Filip K

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Hepatoprotective effects of semaglutide, lanifibranor and dietary intervention in the GAN diet‐induced obese and biopsy‐confirmed mouse model of NASH von Møllerhøj, Mathias B., Veidal, Sanne S., Thrane, Kirstine Tølbøl, Oró, Denise, Overgaard, Agnete, Salinas, Casper Gravesen, Madsen, Martin Rønn, Pfisterer, Larissa, Vyberg, Mogens, Simon, Eric, Broermann, Andre, Vrang, Niels, Jelsing, Jacob, Feigh, Michael, Hansen, Henrik H.

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Dietary intervention reverses molecular markers of hepatocellular senescence in the GAN diet-induced obese and biopsy-confirmed mouse model of NASH von Flensted-Jensen, Mathias, Oró, Denise, Rørbeck, Emma A, Zhang, Chen, Madsen, Martin Rønn, Madsen, Andreas Nygaard, Norlin, Jenny, Feigh, Michael, Larsen, Steen, Hansen, Henrik H

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Characterization of combined linagliptin and Y2R agonist treatment in diet-induced obese mice von Hansen, Henrik H., Grønlund, Rikke V., Baader-Pagler, Tamara, Haebel, Peter, Tammen, Harald, Larsen, Leif Kongskov, Jelsing, Jacob, Vrang, Niels, Klein, Thomas

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Whole-brain activation signatures of weight-lowering drugs von Hansen, Henrik H., Perens, Johanna, Roostalu, Urmas, Skytte, Jacob Lercke, Salinas, Casper Gravesen, Barkholt, Pernille, Thorbek, Ditte Dencker, Rigbolt, Kristoffer T.G., Vrang, Niels, Jelsing, Jacob, Hecksher-Sørensen, Jacob

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The DPP-IV inhibitor linagliptin and GLP-1 induce synergistic effects on body weight loss and appetite suppression in the diet-induced obese rat von Hansen, Henrik H., Hansen, Gitte, Paulsen, Sarah, Vrang, Niels, Mark, Michael, Jelsing, Jacob, Klein, Thomas

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Lipidated PrRP31 metabolites are long acting dual GPR10 and NPFF2 receptor agonists with potent body weight lowering effect von Alexopoulou, Flora, Bech, Esben Matzen, Pedersen, Søren Ljungberg, Thorbek, Ditte Dencker, Leurs, Ulrike, Rudkjær, Lise Christine Biehl, Fosgerau, Keld, Hansen, Henrik H., Vrang, Niels, Jelsing, Jacob, Elster, Lisbeth

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Quantitative whole-brain 3D imaging of tyrosine hydroxylase-labeled neuron architecture in the mouse MPTP model of Parkinson's disease von Roostalu, Urmas, Salinas, Casper B G, Thorbek, Ditte D, Skytte, Jacob L, Fabricius, Katrine, Barkholt, Pernille, John, Linu M, Jurtz, Vanessa Isabell, Knudsen, Lotte Bjerre, Jelsing, Jacob, Vrang, Niels, Hansen, Henrik H, Hecksher-Sørensen, Jacob

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Whole-brain three-dimensional imaging for quantification of drug targets and treatment effects in mouse models of neurodegenerative diseases von Hansen, Henrik, Roostalu, Urmas, Hecksher-Sørensen, Jacob

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6-OR: Renal Cell Type—Associated Therapeutic Effects of Semaglutide in a Mouse Model of Hypertension-Accelerated Diabetic Kidney Disease von TOZZI, MARCO, HANSEN, HENRIK H., CHRISTENSEN, MICHAEL

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1642-P: Metabolic Effects of Semaglutide and Resmetirom at Thermoneutrality in the Diet-Induced Obese Mouse von TOZZI, MARCO, FEIGH, MICHAEL, HANSEN, HENRIK H.

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