Gamma-glutamyl transpeptidase: redox regulation and drug resistance von Hanigan, Marie H

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Gamma-glutamyl compounds: Substrate specificity of gamma-glutamyl transpeptidase enzymes von Wickham, Stephanie, West, Matthew B., Cook, Paul F., Hanigan, Marie H.

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Structure of 6‐diazo‐5‐oxo‐norleucine‐bound human gamma‐glutamyl transpeptidase 1, a novel mechanism of inactivation von Terzyan, Simon S., Cook, Paul F., Heroux, Annie, Hanigan, Marie H.

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Metabolism of cisplatin to a nephrotoxin in proximal tubule cells von TOWNSEND, Danyelle M, MEI DENG, LEI ZHANG, LAPUS, Maia G, HANIGAN, Marie H

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Inhibition of human γ-glutamyl transpeptidase: development of more potent, physiologically relevant, uncompetitive inhibitors von Wickham, Stephanie, Regan, Nicholas, West, Matthew B, Thai, Justin, Cook, Paul F, Terzyan, Simon S, Li, Pui Kai, Hanigan, Marie H

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Design and evaluation of novel analogs of 2-amino-4-boronobutanoic acid (ABBA) as inhibitors of human gamma-glutamyl transpeptidase von Nguyen, Luong, Schultz, Daniel C., Terzyan, Simon S., Rezaei, Mohammad, Songb, Jinhua, Li, Chenglong, You, Youngjae, Hanigan, Marie H.

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SAR of L-ABBA analogs for GGT1 inhibitory activity and L-ABBA's effect on plasma cysteine and GSH species von Bist, Ganesh, Luong, Nguyen T., Mahabubur Rahman, Kazi Md, Ruszaj, Donna M., Li, Chenglong, Hanigan, Marie H., You, Youngjae

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Crystal structures of glutathione- and inhibitor-bound human GGT1: critical interactions within the cysteinylglycine binding site von Terzyan, Simon S., Nguyen, Luong T., Burgett, Anthony W.G., Heroux, Annie, Smith, Clyde A., You, Youngjae, Hanigan, Marie H.

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Novel Insights into Eukaryotic γ-Glutamyltranspeptidase 1 from the Crystal Structure of the Glutamate-bound Human Enzyme von West, Matthew B., Chen, Yunyu, Wickham, Stephanie, Heroux, Ann, Cahill, Kyle, Hanigan, Marie H., Mooers, Blaine H.M.

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Sphingosine-1-Phosphate Lyase Regulates Sensitivity of Human Cells to Select Chemotherapy Drugs in a p38-Dependent Manner von Min, Junxia, Van Veldhoven, Paul P, Zhang, Lei, Hanigan, Marie H, Alexander, Hannah, Alexander, Stephen

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Human γ-Glutamyl Transpeptidase 1: STRUCTURES OF THE FREE ENZYME, INHIBITOR-BOUND TETRAHEDRAL TRANSITION STATES, AND GLUTAMATE-BOUND ENZYME REVEAL NOVEL MOVEMENT WITHIN THE ACTIVE... von Terzyan, Simon S, Burgett, Anthony W G, Heroux, Annie, Smith, Clyde A, Mooers, Blaine H M, Hanigan, Marie H

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Human Tumor Antigens Tn and Sialyl Tn Arise from Mutations in Cosmc von TONGZHONG JU, LANNEAU, Grainger S, LASZIK, Zoltan, BENBROOK, Doris M, HANIGAN, Marie H, CUMMINGS, Richard D, GAUTAM, Tripti, YINGCHUN WANG, BAOYUN XIA, STOWELL, Sean R, WILLARD, Margaret T, WENYI WANG, XIA, Jonathan Y, ZUNA, Rosemary E

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Immunolabeling of gamma-glutamyl transferase 5 in normal human tissues reveals that expression and localization differ from gamma-glutamyl transferase 1 von Hanigan, Marie H., Gillies, Elizabeth M., Wickham, Stephanie, Wakeham, Nancy, Wirsig-Wiechmann, Celeste R.

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Role of glutathione S -transferase Pi in cisplatin-induced nephrotoxicity von Townsend, Danyelle M, Tew, Kenneth D, He, Lin, King, Jarrod B, Hanigan, Marie H

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Autocatalytic Cleavage of Human γ-Glutamyl Transpeptidase Is Highly Dependent on N-Glycosylation at Asparagine 95 von West, Matthew B., Wickham, Stephanie, Quinalty, Leslie M., Pavlovicz, Ryan E., Li, Chenglong, Hanigan, Marie H.

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A Novel, Species-specific Class of Uncompetitive Inhibitors of γ-Glutamyl Transpeptidase von King, Jarrod B., West, Matthew B., Cook, Paul F., Hanigan, Marie H.

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Human GGT2 does not autocleave into a functional enzyme: A cautionary tale for interpretation of microarray data on redox signaling von West, Matthew B, Wickham, Stephanie, Parks, Eileen E, Sherry, David M, Hanigan, Marie H

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Sphingosine Kinase Regulates the Sensitivity of Dictyostelium discoideum Cells to the Anticancer Drug Cisplatin von Min, Junxia, Traynor, David, Stegner, Andrew L, Zhang, Lei, Hanigan, Marie H, Alexander, Hannah, Alexander, Stephen

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N-Acetylcysteine interacts with copper to generate hydrogen peroxide and selectively induce cancer cell death von Zheng, Jie, Lou, Jessica R, Zhang, Xiao-Xi, Benbrook, Doris M, Hanigan, Marie H, Lind, Stuart E, Ding, Wei-Qun

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Stress response inhibits the nephrotoxicity of cisplatin von Hanigan, Marie H, Deng, Mei, Zhang, Lei, Taylor, Jr, Peyton T, Lapus, Maia G

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