Lin28b Is Sufficient to Drive Liver Cancer and Necessary for Its Maintenance in Murine Models von Nguyen, Liem H., Robinton, Daisy A., Seligson, Marc T., Wu, Linwei, Li, Lin, Rakheja, Dinesh, Comerford, Sarah A., Ramezani, Saleh, Sun, Xiankai, Parikh, Monisha S., Yang, Erin H., Powers, John T., Shinoda, Gen, Shah, Samar P., Hammer, Robert E., Daley, George Q., Zhu, Hao

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Acetate Dependence of Tumors von Comerford, Sarah A., Huang, Zhiguang, Du, Xinlin, Wang, Yun, Cai, Ling, Witkiewicz, Agnes K., Walters, Holly, Tantawy, Mohammed N., Fu, Allie, Manning, H. Charles, Horton, Jay D., Hammer, Robert E., McKnight, Steven L., Tu, Benjamin P.

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Hepatic ribosomal protein S6 (Rps6) insufficiency results in failed bile duct development and loss of hepatocyte viability; a ribosomopathy-like phenotype that is partially p53-dep... von Comerford, Sarah A, Hinnant, Elizabeth A, Chen, Yidong, Hammer, Robert E

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Interplay between ChREBP and SREBP-1c coordinates postprandial glycolysis and lipogenesis in livers of mice[S] von Linden, Albert G., Li, Shili, Choi, Hwa Y., Fang, Fei, Fukasawa, Masashi, Uyeda, Kosaku, Hammer, Robert E., Horton, Jay D., Engelking, Luke J., Liang, Guosheng

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Acss2/HIF-2 signaling facilitates colon cancer growth and metastasis von Garcia, Joseph A, Chen, Rui, Xu, Min, Comerford, Sarah A, Hammer, Robert E, Melton, Shelby D, Feagins, Linda A

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White Fat Progenitor Cells Reside in the Adipose Vasculature von Tang, Wei, Zeve, Daniel, Suh, Jae Myoung, Bosnakovski, Darko, Kyba, Michael, Hammer, Robert E, Tallquist, Michelle D, Graff, Jonathan M

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Insulin stimulation of SREBP-1c processing in transgenic rat hepatocytes requires p70 S6-kinase von Owen, Joshua L, Zhang, Yuanyuan, Bae, Soo-Han, Farooqi, Midhat S, Liang, Guosheng, Hammer, Robert E, Goldstein, Joseph L, Brown, Michael S

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Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41 von Samuel, Buck S, Shaito, Abdullah, Motoike, Toshiyuki, Rey, Federico E, Backhed, Fredrik, Manchester, Jill K, Hammer, Robert E, Williams, S. Clay, Crowley, Jan, Yanagisawa, Masashi, Gordon, Jeffrey I

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A Neuroligin-3 Mutation Implicated in Autism Increases Inhibitory Synaptic Transmission in Mice von Tabuchi, Katsuhiko, Blundell, Jacqueline, Etherton, Mark R., Hammer, Robert E., Liu, Xinran, Powell, Craig M., Südhof, Thomas C.

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p53 genes function to restrain mobile elements von Wylie, Annika, Jones, Amanda E, D'Brot, Alejandro, Lu, Wan-Jin, Kurtz, Paula, Moran, John V, Rakheja, Dinesh, Chen, Kenneth S, Hammer, Robert E, Comerford, Sarah A, Amatruda, James F, Abrams, John M

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Modeling Renal Cell Carcinoma in Mice: Bap1 and Pbrm1 Inactivation Drive Tumor Grade von Gu, Yi-Feng, Cohn, Shannon, Christie, Alana, McKenzie, Tiffani, Wolff, Nicholas, Do, Quyen N, Madhuranthakam, Ananth J, Pedrosa, Ivan, Wang, Tao, Dey, Anwesha, Busslinger, Meinrad, Xie, Xian-Jin, Hammer, Robert E, McKay, Renée M, Kapur, Payal, Brugarolas, James

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miR-26 suppresses adipocyte progenitor differentiation and fat production by targeting Fbxl19 von Acharya, Asha, Berry, Daniel C, Zhang, He, Jiang, Yuwei, Jones, Benjamin T, Hammer, Robert E, Graff, Jonathan M, Mendell, Joshua T

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A substitution mutation in a conserved domain of mammalian acetate-dependent acetyl CoA synthetase 2 results in destabilized protein and impaired HIF-2 signaling von Nagati, Jason S, Xu, Min, Garcia, Trent, Comerford, Sarah A, Hammer, Robert E, Garcia, Joseph A

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Deletion of ELOVL5 leads to fatty liver through activation of SREBP-1c in mice von Moon, Young-Ah, Hammer, Robert E., Horton, Jay D.

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FGF21 counteracts alcohol intoxication by activating the noradrenergic nervous system von Choi, Mihwa, Schneeberger, Marc, Fan, Wei, Bugde, Abhijit, Gautron, Laurent, Vale, Kevin, Hammer, Robert E., Zhang, Yuan, Friedman, Jeffrey M., Mangelsdorf, David J., Kliewer, Steven A.

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The master negative regulator REST/NRSF controls adult neurogenesis by restraining the neurogenic program in quiescent stem cells von Gao, Zhengliang, Ure, Kerstin, Ding, Peiguo, Nashaat, Mostafa, Yuan, Laura, Ma, Jing, Hammer, Robert E, Hsieh, Jenny

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LRP1 integrates murine macrophage cholesterol homeostasis and inflammatory responses in atherosclerosis von Xian, Xunde, Ding, Yinyuan, Dieckmann, Marco, Zhou, Li, Plattner, Florian, Liu, Mingxia, Parks, John S, Hammer, Robert E, Boucher, Philippe, Tsai, Shirling, Herz, Joachim

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Bap1 is essential for kidney function and cooperates with Vhl in renal tumorigenesis von Wang, Shan-Shan, Gu, Yi-Feng, Wolff, Nicholas, Stefanius, Karoliina, Christie, Alana, Dey, Anwesha, Hammer, Robert E., Xie, Xian-Jin, Rakheja, Dinesh, Pedrosa, Ivan, Carroll, Thomas, McKay, Renée M., Kapur, Payal, Brugarolas, James

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Target-directed microRNA degradation regulates developmental microRNA expression and embryonic growth in mammals von Jones, Benjamin T, Han, Jaeil, Zhang, He, Hammer, Robert E, Evers, Bret M, Rakheja, Dinesh, Acharya, Asha, Mendell, Joshua T

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Unconventional mechanism of action and resistance to rapalogs in renal cancer von Yang, Juan, Butti, Ramesh, Cohn, Shannon, Toffessi-Tcheuyap, Vanina, Mal, Arijit, Nguyen, Mylinh, Stevens, Christina, Christie, Alana, Mishra, Akhilesh, Ma, Yuanqing, Kim, Jiwoong, Abraham, Robert, Kapur, Payal, Hammer, Robert E, Brugarolas, James

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