Gene Expression Profiling Indicates the Roles of Host Oxidative Stress, Apoptosis, Lipid Metabolism, and Intracellular Transport Genes in the Replication of Hepatitis C Virus von Blackham, Samantha, Baillie, Andrew, Al-Hababi, Fadel, Remlinger, Katja, You, Shihyun, Hamatake, Robert, McGarvey, Michael J

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Identification and structure–activity relationships of substituted pyridones as inhibitors of Pim-1 kinase von Cheney, I. Wayne, Yan, Shunqi, Appleby, Todd, Walker, Heli, Vo, Todd, Yao, Nanhua, Hamatake, Robert, Hong, Zhi, Wu, Jim Z.

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Therapeutic vaccine BRII-179 restores HBV-specific immune responses in patients with chronic HBV in a phase Ib/IIa study von Ma, Haiyan, Lim, Tien Huey, Leerapun, Apinya, Weltman, Martin, Jia, Jidong, Lim, Young-suk, Tangkijvanich, Pisit, Sukeepaisarnjaroen, Wattana, Ji, Yun, Le Bert, Nina, Li, Dong, Zhang, Yao, Hamatake, Robert, Tan, Nicole, Li, Chunming, Strasser, Simone I., Ding, Huiguo, Yoon, Jung-Hwan, Stace, Nigel H., Ahmed, Tanvir, Anderson, Dave E., Yan, Li, Bertoletti, Antonio, Zhu, Qing, Yuen, Man-Fung

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Hepatitis C Replication Inhibitors That Target the Viral NS4B Protein von Miller, John F., Chong, Pek Y., Shotwell, J. Brad, Catalano, John G., Tai, Vincent W.-F., Fang, Jing, Banka, Anna L., Roberts, Christopher D., Youngman, Michael, Zhang, Huichang, Xiong, Zhiping, Mathis, Amanda, Pouliot, Jeffery J., Hamatake, Robert K., Price, Daniel J., Seal, John W., Stroup, Lisa L., Creech, Katrina L., Carballo, Luz H., Todd, Dan, Spaltenstein, Andrew, Furst, Sylvia, Hong, Zhi, Peat, Andrew J.

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Entecavir for Treatment of Hepatitis B Virus Displays No In Vitro Mitochondrial Toxicity or DNA Polymerase Gamma Inhibition von MAZZUCCO, Charles E, HAMATAKE, Robert K, COLONNO, Richard J, TENNEY, Daniel J

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Preclinical Characterization of GSK2336805, a Novel Inhibitor of Hepatitis C Virus Replication That Selects for Resistance in NS5A von WALKER, Jill, CROSBY, Renae, HAMATAKE, Robert, AMY WANG, WOLDU, Ermias, VAMATHEVAN, Jessica, VOITENLEITNER, Christian, SHIHYUN YOU, REMLINGER, Katja, MAOSHANG DUAN, KAZMIERSKI, Wieslaw

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A Randomized, Double‐Blind, Placebo‐Controlled, First‐Time‐in‐Human Study to Assess the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Doses of GSK3389... von Han, Kelong, Cremer, Jennifer, Elston, Robert, Oliver, Stuart, Baptiste‐Brown, Sharon, Chen, Shuguang, Gardiner, David, Davies, Matt, Saunders, Joanne, Hamatake, Robert, Losos, Jan, Leivers, Martin, Hood, Steve, Berg, Frans, Paff, Melanie, Ritter, James M., Theodore, Dickens

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Hepatitis C genotype 1a replicon improved through introduction of fitness mutations von Voitenleitner, Christian, Bechtel, Jill, Arfsten, Ann, Hamatake, Robert

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A Novel Nonnucleoside Analogue That Inhibits Human Immunodeficiency Virus Type 1 Isolates Resistant to Current Nonnucleoside Reverse Transcriptase Inhibitors von ZHIJUN ZHANG, WEN XU, KOH, Yung-Hyo, JAE HOON SHIM, GIRARDET, Jean-Luc, YEH, Li-Tain, HAMATAKE, Robert K, ZHI HONG

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In Vitro Characterization of GSK2485852, a Novel Hepatitis C Virus Polymerase Inhibitor von VOITENLEITNER, Christian, CROSBY, Renae, HORTON, Joseph, CREECH, Katrina, SHOTWELL, J. Brad, ZHI HONG, HAMATAKE, Robert, WALKER, Jill, REMLINGER, Katja, VAMATHEVAN, Jessica, WANG, Amy, SHIHYUN YOU, JOHNSON, John, WOLDU, Ermias, VAN HORN, Stephanie

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Pharmacokinetic characteristics, pharmacodynamic effect and in vivo antiviral efficacy of liver-targeted interferon alpha von Rycroft, Daniel, Sosabowski, Jane, Coulstock, Edward, Davies, Marie, Morrey, John, Friel, Sarah, Kelly, Fiona, Hamatake, Robert, Ovečka, Milan, Prince, Rob, Goodall, Laura, Sepp, Armin, Walker, Adam

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Novel Nonnucleoside Inhibitors That Select Nucleoside Inhibitor Resistance Mutations in Human Immunodeficiency Virus Type 1 Reverse Transcriptase von ZHIJUN ZHANG, WALKER, Michelle, WEN XU, JAE HOON SHIM, GIRARDET, Jean-Luc, HAMATAKE, Robert K, ZHI HONG

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Thiazolone-acylsulfonamides as novel HCV NS5B polymerase allosteric inhibitors: Convergence of structure-based drug design and X-ray crystallographic study von Yan, Shunqi, Appleby, Todd, Larson, Gary, Wu, Jim Z., Hamatake, Robert K., Hong, Zhi, Yao, Nanhua

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In Vitro Inhibition of Hepadnavirus Polymerases by the Triphosphates of BMS-200475 and Lobucavir von SEIFER, M, HAMATAKE, R. K, COLONNO, R. J, STANDRING, D. N

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Hepatitis B and d Protocols: Volume 2: Immunology, Model Systems, and Clinical Studies von Hamatake, Robert K, Lau, Johnson Y. N

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Isothiazoles as active-site inhibitors of HCV NS5B polymerase von Yan, Shunqi, Appleby, Todd, Gunic, Esmir, Shim, Jae Hoon, Tasu, Tania, Kim, Hongwoo, Rong, Frank, Chen, Huaming, Hamatake, Robert, Wu, Jim Z., Hong, Zhi, Yao, Nanhua

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Cyclic monophosphate prodrugs of base-modified 2′- C-methyl ribonucleosides as potent inhibitors of hepatitis C virus RNA replication von Gunic, Esmir, Girardet, Jean-Luc, Ramasamy, Kanda, Stoisavljevic-Petkov, Vesna, Chow, Suetying, Yeh, Li-Tain, Hamatake, Robert K., Raney, Anneke, Hong, Zhi

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Duck Hepatitis B Virus Model in the Study of Hepatitis B Virus von Cova, Lucyna, Zoulim, Fabien

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Hepatitis B and d Protocols: Volume 1: Detection, Genotypes, and Characterization von Hamatake, Robert K, Lau, Johnson Y. N

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The Tupaia Model for the Study of Hepatitis B Virus: Direct Infection and HBV Genome Transduction of Primary Tupaia Hepatocytes von von Weizsäcker, Fritz, Köck, Josef, MacNelly, Sabine, Ren, Shaotang, Blum, Hubert E., Nassal, Michael

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