Role of Complement and Complement Regulatory Proteins in the Complications of Diabetes von Ghosh, Pamela, Sahoo, Rupam, Vaidya, Anand, Chorev, Michael, Halperin, Jose A

Volltext

Small-Molecule Inhibition of the Interaction between the Translation Initiation Factors eIF4E and eIF4G von Moerke, Nathan J., Aktas, Huseyin, Chen, Han, Cantel, Sonia, Reibarkh, Mikhail Y., Fahmy, Amr, Gross, John D., Degterev, Alexei, Yuan, Junying, Chorev, Michael, Halperin, Jose A., Wagner, Gerhard

Volltext

Plasma glycated CD59 predicts postpartum glucose intolerance after gestational diabetes von Benhalima, Katrien, Ma, Diane D, Laenen, Annouschka, Mathieu, Chantal, Halperin, Jose A

Volltext

Plasma Glycated CD59, a Novel Biomarker for Detection of Pregnancy-Induced Glucose Intolerance von Ghosh, Pamela, Luque-Fernandez, Miguel A, Vaidya, Anand, Ma, Dongdong, Sahoo, Rupam, Chorev, Michael, Zera, Chloe, McElrath, Thomas F, Williams, Michelle A, Seely, Ellen W, Halperin, Jose A

Volltext

The Role of Early Pregnancy Maternal pGCD59 Levels in Predicting Neonatal Hypoglycemia-Subanalysis of the DALI Study von Bogdanet, Delia, Luque-Fernandez, Miguel Angel, Toth-Castillo, Michelle, Desoye, Gernot, O'Shea, Paula M, Dunne, Fidelma P, Halperin, Jose A

Volltext

Enhanced complement activation and MAC formation accelerates severe COVID-19 von Ellsworth, Calder R., Chen, Zheng, Xiao, Mark T., Qian, Chaosi, Wang, Chenxiao, Khatun, Mst Shamima, Liu, Shumei, Islamuddin, Mohammad, Maness, Nicholas J., Halperin, Jose A., Blair, Robert V., Kolls, Jay K., Tomlinson, Stephen, Qin, Xuebin

Volltext

Structure of the eukaryotic translation initiation factor eIF4E in complex with 4EGI-1 reveals an allosteric mechanism for dissociating eIF4G von Papadopoulos, Evangelos, Jenni, Simon, Kabha, Eihab, Takrouri, Khuloud J, Yi, Tingfang, Salvi, Nicola, Luna, Rafael E, Gavathiotis, Evripidis, Mahalingam, Poornachandran, Arthanari, Haribabu, Rodriguez-Mias, Ricard, Yefidoff-Freedman, Revital, Aktas, Bertal H, Chorev, Michael, Halperin, Jose A, Wagner, Gerhard

Volltext

Glycation of the Complement Regulatory Protein CD59 Is a Novel Biomarker for Glucose Handling in Humans von Ghosh, Pamela, Vaidya, Anand, Sahoo, Rupam, Goldfine, Allison, Herring, Neil, Bry, Lynn, Chorev, Michael, Halperin, Jose A

Volltext

Synthesis and Conformational Analysis of a Cyclic Peptide Obtained via i to i+4 Intramolecular Side-Chain to Side-Chain Azide−Alkyne 1,3-Dipolar Cycloaddition von Cantel, Sonia, Le Chevalier Isaad, Alexandra, Scrima, Mario, Levy, Jay J, DiMarchi, Richard D, Rovero, Paolo, Halperin, Jose A, D’Ursi, Anna Maria, Papini, Anna Maria, Chorev, Michael

Volltext

Human CD59 Inhibitor Sensitizes Rituximab-Resistant Lymphoma Cells to Complement-Mediated Cytolysis von WEIGUO HU, XIAOWEN GE, BROWN, Jennifer R, XUEBIN QIN, TAO YOU, TING XU, JINYAN ZHANG, GONGXIONG WU, ZHIHAI PENG, CHOREV, Michael, AKTAS, Bertal H, HALPERIN, Jose A

Volltext

The ability of pGCD59 to predict adverse pregnancy outcomes: a prospective study of non-diabetic pregnant women in Ireland von Bogdanet, Delia, Castillo, Michelle Toth, Doheny, Helen, Dervan, Louise, Luque-Fernandez, Miguel Angel, Halperin, Jose A., O’Shea, Paula M., Dunne, Fidelma P.

Volltext

Complement Regulator CD59 Protects Against Atherosclerosis by Restricting the Formation of Complement Membrane Attack Complex von Wu, Gongxiong, Hu, Weiguo, Shahsafaei, Aliakbar, Song, Wenping, Dobarro, Martin, Sukhova, Galina K, Bronson, Rod R, Shi, Guo-ping, Rother, Russell P, Halperin, Jose A, Qin, Xuebin

Volltext

Cell surface complement regulators moderate experimental myasthenia gravis pathology von Kusner, Linda L., Halperin, Jose A., Kaminski, Henry J.

Volltext

The Diagnostic Accuracy of Second Trimester Plasma Glycated CD59 (pGCD59) to Identify Women with Gestational Diabetes Mellitus Based on the 75 g OGTT Using the WHO Criteria: A Pros... von Bogdanet, Delia, Toth Castillo, Michelle, Doheny, Helen, Dervan, Louise, Luque-Fernandez, Miguel-Angel, Halperin, Jose A, O'Shea, Paula M, Dunne, Fidelma P

Volltext

Ultrahigh-resolution (1)H-(13)C HSQC spectra of metabolite mixtures using nonlinear sampling and forward maximum entropy reconstruction von Hyberts, Sven G, Heffron, Gregory J, Tarragona, Nestor G, Solanky, Kirty, Edmonds, Katherine A, Luithardt, Harry, Fejzo, Jasna, Chorev, Michael, Aktas, Huseyin, Colson, Kimberly, Falchuk, Kenneth H, Halperin, Jose A, Wagner, Gerhard

Volltext

DAF/CD55 and Protectin/CD59 modulate adaptive immunity and disease outcome in experimental autoimmune myasthenia gravis von Soltys, Jindrich, Halperin, Jose A, Xuebin, Qin

Volltext

Small-Molecule targeting of translation initiation for cancer therapy von Aktas, Bertal H, Qiao, Yuan, Ozdelen, Esra, Schubert, Roland, Sevinc, Sema, Harbinski, Fred, Grubissich, Luciano, Singer, Samuel, Halperin, Jose A

Volltext

Depletion of eIF2·GTP·Met-tRNAi translation initiation complex up-regulates BRCA1 expression in vitro and in vivo von Aktas, Bertal H, Bordelois, Paula, Peker, Selen, Merajver, Sophia, Halperin, Jose A

Volltext

3-Substituted Indazoles as Configurationally Locked 4EGI-1 Mimetics and Inhibitors of the eIF4E/eIF4G Interaction von Yefidoff-Freedman, Revital, Chen, Ting, Sahoo, Rupam, Chen, Limo, Wagner, Gerhard, Halperin, Jose A., Aktas, Bertal H., Chorev, Michael

Volltext

Complement Regulator CD59 Protects Against Angiotensin II-Induced Abdominal Aortic Aneurysms in Mice von GONGXIONG WU, TING CHEN, SHAHSAFAEI, Aliakbar, WEIGUO HU, BRONSON, Roderick T, SHI, Guo-Ping, HALPERIN, Jose A, AKTAS, Huseyin, XUEBIN QIN

Volltext