The Race to Bash NASH: Emerging Targets and Drug Development in a Complex Liver Disease von Romero, F. Anthony, Jones, Christopher T, Xu, Yingzi, Fenaux, Martijn, Halcomb, Randall L

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GS-9620, an Oral Agonist of Toll-Like Receptor-7, Induces Prolonged Suppression of Hepatitis B Virus in Chronically Infected Chimpanzees von Lanford, Robert E, Guerra, Bernadette, Chavez, Deborah, Giavedoni, Luis, Hodara, Vida L, Brasky, Kathleen M, Fosdick, Abigail, Frey, Christian R, Zheng, Jim, Wolfgang, Grushenka, Halcomb, Randall L, Tumas, Daniel B

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Pharmacokinetic and pharmacodynamic properties of GS-9620, a novel Toll-like receptor 7 agonist, demonstrate interferon-stimulated gene induction without detectable serum interfero... von Fosdick, Abigail, Zheng, Jim, Pflanz, Stefan, Frey, Christian R, Hesselgesser, Joseph, Halcomb, Randall L, Wolfgang, Grushenka, Tumas, Daniel B

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Identification and Optimization of Pteridinone Toll-like Receptor 7 (TLR7) Agonists for the Oral Treatment of Viral Hepatitis von Roethle, Paul A, McFadden, Ryan M, Yang, Hong, Hrvatin, Paul, Hui, Hon, Graupe, Michael, Gallagher, Brian, Chao, Jessica, Hesselgesser, Joseph, Duatschek, Paul, Zheng, Jim, Lu, Bing, Tumas, Daniel B, Perry, Jason, Halcomb, Randall L

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Total Synthesis of (+)-Phomactin A Using a B-Alkyl Suzuki Macrocyclization von Mohr, Peter J, Halcomb, Randall L

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Selective thyroid hormone receptor β agonists with oxadiazolone acid isosteres von Kirschberg, Thorsten A., Jones, Christopher T., Xu, Yingzi, Fenaux, Martijn, Halcomb, Randall L., Wang, Yujin, Klucher, Kevin

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Synthesis of the Ring System of Phomactin D Using a Suzuki Macrocyclization von Kallan, Nicholas C, Halcomb, Randall L

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Synthesis of an Isostere of an O-Linked Glycopeptide von Whalen, Lisa J, Halcomb, Randall L

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On the direct epoxidation of glycals: application of a reiterative strategy for the synthesis of .beta.-linked oligosaccharides von Halcomb, Randall L, Danishefsky, Samuel J

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Synthesis of a Six-Carbon Sialic Acid Using an Indium-Mediated Coupling von Chappell, Mark D, Halcomb, Randall L

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Solution- and Solid-Phase Synthesis of Inhibitors of H. pylori Attachment and E-Selectin-Mediated Leukocyte Adhesion von Halcomb, Randall L, Huang, Hongmei, Wong, Chi-Huey

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Design and Synthesis of Conformationally Constrained Glycosylated Amino Acids von Koviach, Jennifer L, Chappell, Mark D, Halcomb, Randall L

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Antibody–Drug Conjugates (ADCs) Derived from Interchain Cysteine Cross-Linking Demonstrate Improved Homogeneity and Other Pharmacological Properties over Conventional Heterogeneous... von Behrens, Christopher R, Ha, Edward H, Chinn, Lawrence L, Bowers, Simeon, Probst, Gary, Fitch-Bruhns, Maureen, Monteon, Jorge, Valdiosera, Amanda, Bermudez, Abel, Liao-Chan, Sindy, Wong, Tiffany, Melnick, Jonathan, Theunissen, Jan-Willem, Flory, Mark R, Houser, Derrick, Venstrom, Kristy, Levashova, Zoia, Sauer, Paul, Migone, Thi-Sau, van der Horst, Edward H, Halcomb, Randall L, Jackson, David Y

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Application of Serine- and Threonine-Derived Cyclic Sulfamidates for the Preparation of S-Linked Glycosyl Amino Acids in Solution- and Solid-Phase Peptide Synthesis von Cohen, Scott B, Halcomb, Randall L

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Ligand Recognition by E-Selectin: Synthesis, Inhibitory Activity and Conformational Analysis of Bivalent Sialyl Lewis x Analogs von DeFrees, Shawn A, Kosch, Winfried, Way, William, Paulson, James C, Sabesan, Subramanian, Halcomb, Randall L, Huang, Dee-Hua, Ichikawa, Yoshitaka, Wong, Chi-Huey

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New design concepts for constraining glycosylated amino acids von Lane, Jonathan W, Halcomb, Randall L

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Exploration of factors driving incorporation of unnatural dNTPS into DNA by Klenow fragment (DNA polymerase I) and DNA polymerase α von Kincaid, Kristi, Beckman, Jeff, Zivkovic, Aleksandra, Halcomb, Randall L., Engels, Joachim W., Kuchta, Robert D.

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Convergent Enantioselective Synthesis of the Tricyclic Core of Phomactin A von Mohr, Peter J, Halcomb, Randall L

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Clinical targeting of HIV capsid protein with a long-acting small molecule von Link, John O., Rhee, Martin S., Tse, Winston C., Zheng, Jim, Somoza, John R., Rowe, William, Begley, Rebecca, Chiu, Anna, Mulato, Andrew, Hansen, Derek, Singer, Eric, Tsai, Luong K., Bam, Rujuta A., Chou, Chien-Hung, Canales, Eda, Brizgys, Gediminas, Zhang, Jennifer R., Li, Jiayao, Graupe, Michael, Morganelli, Philip, Liu, Qi, Wu, Qiaoyin, Halcomb, Randall L., Saito, Roland D., Schroeder, Scott D., Lazerwith, Scott E., Bondy, Steven, Jin, Debi, Hung, Magdeleine, Novikov, Nikolai, Liu, Xiaohong, Villaseñor, Armando G., Cannizzaro, Carina E., Hu, Eric Y., Anderson, Robert L., Appleby, Todd C., Lu, Bing, Mwangi, Judy, Liclican, Albert, Niedziela-Majka, Anita, Papalia, Giuseppe A., Wong, Melanie H., Leavitt, Stephanie A., Xu, Yili, Koditek, David, Stepan, George J., Yu, Helen, Pagratis, Nikos, Clancy, Sheila, Ahmadyar, Shekeba, Cai, Terrence Z., Sellers, Scott, Wolckenhauer, Scott A., Ling, John, Callebaut, Christian, Margot, Nicolas, Ram, Renee R., Liu, Ya-Pei, Hyland, Rob, Sinclair, Gary I., Ruane, Peter J., Crofoot, Gordon E., McDonald, Cheryl K., Brainard, Diana M., Lad, Latesh, Swaminathan, Swami, Sundquist, Wesley I., Sakowicz, Roman, Chester, Anne E., Lee, William E., Daar, Eric S., Yant, Stephen R., Cihlar, Tomas

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Synthesis of S-Linked Glycosyl Amino Acids in Aqueous Solution with Unprotected Carbohydrates von Cohen, Scott B, Halcomb, Randall L

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