A Pharmacokinetic and Pharmacodynamic Analysis of CPT‐11 and Its Active Metabolite SN‐38 von Sasaki, Yasutsuna, Hakusui, Hideo, Mizuno, Shoichi, Morita, Masashige, Miya, Toshimichi, Eguchi, Kenji, Shinkai, Tetsu, Tamura, Tomohide, Ohe, Yuichiro, Saijo, Nagahiro

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Interaction of Quinolones with Metal Cations in Aqueous Solution von KAWAI, Yukinori, MATSUBAYASHI, Kyuichi, HAKUSUI, Hideo

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Direct HPLC separation of enantiomers of pantoprazole and other benzimidazole sulfoxides using cellulose-based chiral stationary phases in reversed-phase mode von Tanaka, Makoto, Yamazaki, Hideki, Hakusui, Hideo

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Pharmacological Correlation between Total Drug Concentration and Lactones of CPT‐11 and SN‐38 in Patients Treated with CPT‐11 von Sasaki, Yasutsuna, Yoshida, Yasushi, Sudoh, Kenichi, Hakusui, Hideo, Fujii, Hirofumi, Ohtsu, Tomoko, Wakita, Hisashi, Igarashi, Tadahiko, Itoh, Kuniaki

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Pharmacokinetics and Safety of Ascending Single Doses of DZ-2640, a New Oral Carbapenem Antibiotic, Administered to Healthy Japanese Subjects von TANAKA, M, KATO, K, HAKUSUI, H, MURAKAMI, Y, SATO, K, ITO, Y, KAWAMOTO, K

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Assay and Disposition of Carvedilol Enantiomers in Humans and Monkeys: Evidence of Stereoselective Presystemic Metabolism von Fujimaki, Masayoshi, Murakoshi, Yuklko, Hakusui, Hideo

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Effects of proton pump inhibitors on thyroid hormone metabolism in rats von Masubuchi, Noriko, Hakusui, Hideo, Okazaki, Osamu

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Effect of Dehydration on the Formation of Levofloxacin Pseudopolymorphs von KITAOKA, Hiroaki, WADA, Chisa, MOROI, Reimei, HAKUSUI, Hideo

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Metabolism of Irinotecan to SN-38 in a Tissue-Isolated Tumor Model von ATSUMI, Ryo, OKAZAKI, Osamu, HAKUSUI, Hideo

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Chemical Characterization of a Sulfated Polysaccharide-Peptidoglycan Complex from an Arthrobacter sp von Yamazaki, Ken-ichi, Suzuki, Makoto, Inukai, Kazuyoshi, Hakusui, Hideo

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Metabolic Activation of CPT-11, 7-Ethyl-10-[4-(1-piperidino)-1-piperidino] carbonyloxycamptothecin, a Novel Antitumor Agent, by Carboxylesterase von SATOH, Tetsuo, HOSOKAWA, Masakiyo, ATSUMI, Ryo, SUZUKI, Wataru, HAKUSUI, Hideo, NAGAI, Eiichi

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Thermal Dehydration of Nafagrel Hydrochloride Hydrate at Controlled Water Vapor Partial Pressures von KITAOKA, Hiroaki, OHYA, Kazumi, HAKUSUI, Hideo

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Pharmacokinetics of SN-38 ((+)-(4S)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano(3',4':6,7)-indolizino(1,2-b)quinoline-3,14(4H,12H)-dione), an Active Metabolite of Irinotecan, after a Sing... von ATSUMI, Ryo, OKAZAKI, Osamu, HAKUSUI, Hideo

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Metabolic disposition of pantoprazole, a proton pump inhibitor, in relation to S‐mephenytoin 4′‐hydroxylation phenotype and genotype von Tanaka, Makoto, Ohkubo, Tadashi, Otani, Koichi, Suzuki, Akihito, Kaneko, Sunao, Sugawara, Kazunobu, Ryokawa, Yuichi, Hakusui, Hideo, Yamamori, Shunji, Ishizaki, Takashi

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Modulation of Subcellular Particles of the Rat Small Intestine and Liver by Ebselen von MIZOGUCHI, Tadashi, NISHINAKA, Tohru, NANJO, Hirofumi, YAGI, Kiyohito, HAKUSUI, Hideo

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Resolution of enantiomers of a novel thromboxane synthetase inhibitor by HPLC on a chiral stationary phase von TANAKA, Makoto, HAKUSUI, Hideo

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Metabolic Activation of CPT-11, 7-Ethyl-10-(4-(1-piperidino)-1-piperidino)carbonyloxycamptothecin, a Novel Antitumor Agent, by Carboxylesterase von SATOH, Tetsuo, HOSOKAWA, Masakiyo, ATSUMI, Ryo, SUZUKI, Wataru, HAKUSUI, Hideo, NAGAI, Eiichi

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Effects of proton pump inhibitors on thyroid hormone metabolism in rats: A comparison of UDP-glucuronyltransferase induction von Masubuchi, Noriko, Hakusui, Hideo, Okazaki, Osamu

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Report on Questionnaires about the Present and the New PK Guidelines of Japan to Companies in JPMA von HAKUSUI, Hideo

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TOXICOKINETICS:ITS SIGNIFICANCE AND PRACTICAL PROBLEMS von KATO, Ryuichi, CASE, David E., HAKUSUI, Hideo, NODA, Kosei, SAGAMI, Fumio, HORII, Ikuo, MAYAHARA, Hiroshi, CAYEN, Mitchell N., MARRIOTT, Thomas B., IGARASHI, Toshiji

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