Human B Cells Secrete Granzyme B When Recognizing Viral Antigens in the Context of the Acute Phase Cytokine IL-21 von Hagn, Magdalena, Schwesinger, Elisabeth, Ebel, Verena, Sontheimer, Kai, Maier, Julia, Beyer, Thamara, Syrovets, Tatiana, Laumonnier, Yves, Fabricius, Dorit, Simmet, Thomas, Jahrsdorfer, Bernd

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B-CLL cells acquire APC- and CTL-like phenotypic characteristics after stimulation with CpG ODN and IL-21 von Hagn, Magdalena, Blackwell, Sue E, Beyer, Thamara, Ebel, Verena, Fabricius, Dorit, Lindner, Stefanie, Stilgenbauer, Stefan, Simmet, Thomas, Tam, Constantine, Neeson, Paul, Trapani, Joseph A, Schrezenmeier, Hubert, Weiner, George J, Jahrsdörfer, Bernd

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Why do human B cells secrete granzyme B? Insights into a novel B-cell differentiation pathway von Hagn, Magdalena, Jahrsdörfer, Bernd

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Interleukin 21―Induced Granzyme B―Expressing B Cells Infiltrate Tumors and Regulate T Cells von LINDNER, Stefanie, DAHLKE, Karen, LUNOV, Oleg, NIENHAUS, G. Ulrich, SIMMET, Thomas, KREIENBERG, Rolf, MÖLLER, Peter, SCHREZENMEIER, Hubert, JAHRSDÖRFER, Bernd, SONTHEIMER, Kai, HAGN, Magdalena, KALTENMEIER, Christof, BARTH, Thomas F. E, BEYER, Thamara, REISTER, Frank, FABRICIUS, Dorit, LOTFI, Ramin

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Human B cells differentiate into granzyme B-secreting cytotoxic B lymphocytes upon incomplete T-cell help von Hagn, Magdalena, Sontheimer, Kai, Dahlke, Karen, Brueggemann, Sabine, Kaltenmeier, Christof, Beyer, Thamara, Hofmann, Stefanie, Lunov, Oleg, Barth, Thomas FE, Fabricius, Dorit, Tron, Kyrylo, Nienhaus, Gerd Ulrich, Simmet, Thomas, Schrezenmeier, Hubert, Jahrsdörfer, Bernd

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A method for detecting intracellular perforin in mouse lymphocytes von Brennan, Amelia J, House, Imran G, Oliaro, Jane, Ramsbottom, Kelly M, Hagn, Magdalena, Yagita, Hideo, Trapani, Joseph A, Voskoboinik, Ilia

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Activated mouse B cells lack expression of granzyme B von Hagn, Magdalena, Belz, Gabrielle T, Kallies, Axel, Sutton, Vivien R, Thia, Kevin Y, Tarlinton, David M, Hawkins, Edwin D, Trapani, Joseph A

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A Colorimetric Assay that Specifically Measures Granzyme B Proteolytic Activity: Hydrolysis of Boc-Ala-Ala-Asp-S-Bzl von Hagn, Magdalena, Sutton, Vivien R., Trapani, Joseph A.

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CD5⁺ B cells from individuals with systemic lupus erythematosus express granzyme B von Hagn, Magdalena, Ebel, Verena, Sontheimer, Kai, Schwesinger, Elisabeth, Lunov, Oleg, Beyer, Thamara, Fabricius, Dorit, Barth, Thomas F.E, Viardot, Andreas, Stilgenbauer, Stephan, Hepp, Julia, Scharffetter-Kochanek, Karin, Simmet, Thomas, Jahrsdörfer, Bernd

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A colorimetric assay that specifically measures Granzyme B proteolytic activity: hydrolysis of Boc-Ala-Ala-Asp-S-Bzl von Hagn, Magdalena, Sutton, Vivien R, Trapani, Joseph A

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CD27(+)IgD(-) B cells in the peripheral blood of colorectal cancer patients: on anti-tumor or tumor-protective mission? von Jahrsdörfer, Bernd, Lindner, Stefanie, Hagn, Magdalena, Schrezenmeier, Hubert

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Viral and bacterial antigens as well as agonists for TLR4 and TLR9 can trigger granzyme B secretion by human B cells in the presence of interleukin 21 (154.21) von Kaltenmeier, Christof, Brüggeman, Sabine, Beyer, Thamara, Sontheimer, Kai, Hagn, Magdalena, Simmet, Thomas, Jahrsdörfer, Bernd

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Naïve B Cells Differentiate into Highly Activated Granzyme B-Secreting B Cells in Response to Interleukin 21 and B Cell Receptor Stimulation von Schwesinger, Elisabeth, Hagn, Magdalena, Simmet, Thomas, Jahrsdoerfer, Bernd

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Specific Induction of Granzyme B in Human B Cells by Viral Antigens von Hagn, Magdalena, Maier, Julia, Syrovets, Tatjana, Simmet, Thomas, Jahrsdoerfer, Bernd

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Naïve B Cells Differentiate into Highly Activated Granzyme B-Secreting B Cells in Response to Interleukin 21 and B Cell Receptor Stimulation von Schwesinger, Elisabeth, Hagn, Magdalena, Simmet, Thomas, Jahrsdoerfer, Bernd

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Interleukin-21-induced granzyme B-expressing B lymphocytes regulate T cells and infiltrate tumors (P1088) von Lindner, Stefanie, Dahlke, Karen, Sontheimer, Kai, Hagn, Magdalena, Kaltenmeier, Christof, Barth, Thomas, Beyer, Thamara, Reister, Frank, Fabricius, Dorit, Lotfi, Ramin, Lunov, Oleg, Nienhaus, G. Ulrich, Simmet, Thomas, Kreienberg, Rolf, Möller, Peter, Schrezenmeier, Hubert, Jahrsdörfer, Bernd

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Viral Antigens Trigger Granzyme B Secretion by Human CD5+ B1 Cells in the Presence of Interleukin 21 von Sontheimer, Kai, Hagn, Magdalena, Ebel, Verena, Beyer, Thamara, Simmet, Thomas, Jahrsdörfer, Bernd

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Interleukin-21-Induced Granzyme B-Expressing B Lymphocytes Infiltrate Tumors and Regulate T Cells von Lindner, Stefanie, Dahlke, Karen, Sontheimer, Kai, Hagn, Magdalena, Kaltenmeier, Christof, Barth, Thomas F.E., Beyer, Thamara, Reister, Frank, Fabricius, Dorit, Lotfi, Ramin, Lunov, Oleg, Nienhaus, Ulrich, Simmet, Thomas, Kreienberg, Rolf, Moeller, Peter, Schrezenmeier, Hubert, Jahrsdörfer, Bernd

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Induction of a CTL-Like Phenotype In B-CLL Cells Stimulated with Interleukin 21 and CpG Oligodeoxynucleotides von Jahrsdoerfer, Bernd, Blackwell, Sue E, Hagn, Magdalena, Ebel, Verena, Beyer, Thamara, Sontheimer, Kai, Dahlke, Karen, Weiner, George, Simmet, Thomas

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Viral Antigens Trigger Granzyme B Secretion by Human CD5+ B1 Cells in the Presence of Interleukin 21 von Sontheimer, Kai, Blackwell, Sue, Hagn, Magdalena, Ebel, Verena, Beyer, Thamara, Simmet, Thomas, Jahrsdoerfer, Bernd

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