Genetic Ablation of CD38 Protects against Western Diet-Induced Exercise Intolerance and Metabolic Inflexibility von Chiang, Shian-Huey, Harrington, W Wallace, Luo, Guizhen, Milliken, Naphtali O, Ulrich, John C, Chen, Jing, Rajpal, Deepak K, Qian, Ying, Carpenter, Tiffany, Murray, Rusty, Geske, Robert S, Stimpson, Stephen A, Kramer, Henning F, Haffner, Curt D, Becherer, J David, Preugschat, Frank, Billin, Andrew N

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Discovery, Synthesis, and Biological Evaluation of Thiazoloquin(az)olin(on)es as Potent CD38 Inhibitors von Haffner, Curt D, Becherer, J. David, Boros, Eric E, Cadilla, Rodolfo, Carpenter, Tiffany, Cowan, David, Deaton, David N, Guo, Yu, Harrington, Wallace, Henke, Brad R, Jeune, Michael R, Kaldor, Istvan, Milliken, Naphtali, Petrov, Kim G, Preugschat, Frank, Schulte, Christie, Shearer, Barry G, Shearer, Todd, Smalley, Terrence L, Stewart, Eugene L, Stuart, J. Darren, Ulrich, John C

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Differential recognition of HIV-stimulated IL-1β and IL-18 secretion through NLR and NAIP signalling in monocyte-derived macrophages von Triantafilou, Kathy, Ward, Christopher J K, Czubala, Magdalena, Ferris, Robert G, Koppe, Emma, Haffner, Curt, Piguet, Vincent, Patel, Vipulkumar K, Amrine-Madsen, Heather, Modis, Louise K, Masters, Seth L, Triantafilou, Martha

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Discovery of 4‑Amino-8-quinoline Carboxamides as Novel, Submicromolar Inhibitors of NAD-Hydrolyzing Enzyme CD38 von Becherer, J. David, Boros, Eric E., Carpenter, Tiffany Y., Cowan, David J., Deaton, David N., Haffner, Curt D., Jeune, Michael R., Kaldor, Istvan W., Poole, J. Chuck, Preugschat, Frank, Rheault, Tara R., Schulte, Christie A., Shearer, Barry G., Shearer, Todd W., Shewchuk, Lisa M., Smalley, Terrence L., Stewart, Eugene L., Stuart, J. Darren, Ulrich, John C.

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2,4-Diamino-8-quinazoline carboxamides as novel, potent inhibitors of the NAD hydrolyzing enzyme CD38: Exploration of the 2-position structure-activity relationships von Deaton, David N., Haffner, Curt D., Henke, Brad R., Jeune, Michael R., Shearer, Barry G., Stewart, Eugene L., Stuart, J. Darren, Ulrich, John C.

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Identification of a Chemical Tool for the Orphan Nuclear Receptor FXR von Maloney, Patrick R, Parks, Derek J, Haffner, Curt D, Fivush, Adam M, Chandra, Gyan, Plunket, Kelli D, Creech, Katrina L, Moore, Linda B, Wilson, Joan G, Lewis, Michael C, Jones, Stacey A, Willson, Timothy M

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Discovery of Pyrazolocarboxamides as Potent and Selective Receptor Interacting Protein 2 (RIP2) Kinase Inhibitors von Haffner, Curt D, Charnley, Adam K, Aquino, Christopher J, Casillas, Linda, Convery, Máire A, Cox, Julie A, Elban, Mark A, Goodwin, Nicole C, Gough, Peter J, Haile, Pamela A, Hughes, Terry V, Knapp-Reed, Beth, Kreatsoulas, Constantine, Lakdawala, Ami S, Li, Huijie, Lian, Yiqian, Lipshutz, David, Mehlmann, John F, Ouellette, Michael, Romano, Joseph, Shewchuk, Lisa, Shu, Arthur, Votta, Bartholomew J, Zhou, Huiqiang, Bertin, John, Marquis, Robert W

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Novel selective small molecule agonists for peroxisome proliferator-activated receptor δ (PPARδ)—synthesis and biological activity von Sznaidman, Marcos L., Haffner, Curt D., Maloney, Patrick R., Fivush, Adam, Chao, Esther, Goreham, Donna, Sierra, Michael L., LeGrumelec, Christelle, Xu, H.Eric, Montana, Valerie G., Lambert, Millard H., Willson, Timothy M., Oliver, William R., Sternbach, Daniel D.

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Pyrrolidinyl pyridone and pyrazinone analogues as potent inhibitors of prolyl oligopeptidase (POP) von Haffner, Curt D., Diaz, Caroline J., Miller, Aaron B., Reid, Robert A., Madauss, Kevin P., Hassell, Annie, Hanlon, Mary H., Porter, David J.T., Becherer, J. David, Carter, Luke H.

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N-{3-[(1,1-dioxido-1,2-benzothiazol-3-yl)(phenyl)amino]propyl}benzamide analogs as potent Kv1.3 inhibitors. Part 1 von Haffner, Curt D., Thomson, Stephen A., Guo, Yu, Schaller, Lee T., Boggs, Sharon, Dickerson, Scott, Gobel, Jeff, Gillie, Dan, Condreay, J. Patrick

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Substituted N-{3-[(1,1-dioxido-1,2-benzothiazol-3-yl)(phenyl)amino]propyl}benzamide analogs as potent Kv1.3 ion channel blockers. Part 2 von Haffner, Curt D., Thomson, Stephen A., Guo, Yu, Petrov, Kimberly, Larkin, Andrew, Banker, Pierette, Schaaf, Gregory, Dickerson, Scott, Gobel, Jeff, Gillie, Dan, Condreay, J. Patrick, Poole, Chuck, Carpenter, Tiffany, Ulrich, John

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The Palladium-Catalyzed Enyne Cycloisomerization Reaction in a General Approach to the Asymmetric Syntheses of the Picrotoxane Sesquiterpenes. Part I. First-Generation Total Synthe... von Trost, Barry M, Haffner, Curt D, Jebaratnam, David J, Krische, Michael J, Thomas, Andrew P

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Structure-Based Design of Potent Retinoid X Receptor α Agonists von Haffner, Curt D., Lenhard, James M., Miller, Aaron B., McDougald, Darryl L., Dwornik, Kate, Ittoop, Olivia R., Gampe, Robert T., Xu, H. Eric, Blanchard, Steve, Montana, Valerie G., Consler, Tom G., Bledsoe, Randy K., Ayscue, Andrea, Croom, Dallas

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2-Cyano-4-fluoro-1-thiovalylpyrrolidine analogues as potent inhibitors of DPP-IV von Haffner, Curt D., McDougald, Darryl L., Reister, Steven M., Thompson, Brian D., Conlee, Christopher, Fang, Jing, Bass, Jonathan, Lenhard, James M., Croom, Dallas, Secosky-Chang, Melissa B., Tomaszek, Thaddeus, McConn, Donavon, Wells-Knecht, Kevin, Johnson, Paul R.

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Differential recognition of HIV-stimulated IL-1[beta] and IL-18 secretion through NLR and NAIP signalling in monocyte-derived macrophages von Triantafilou, Kathy, Ward, Christopher J. K, Czubala, Magdalena, Ferris, Robert G, Koppe, Emma, Haffner, Curt, Piguet, Vincent, Patel, Vipulkumar K, Amrine-Madsen, Heather, Modis, Louise, Masters, Seth L, Triantafilou, Martha

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N-{3-[(1,1-dioxido-1,2-benzothiazol-3-yl)(phenyl)amino]propyl}benz amide analogs as potent Kv1.3 inhibitors. Part 1 von Haffner, Curt D, Thomson, Stephen A, Guo, Yu, Schaller, Lee T, Boggs, Sharon, Dickerson, Scott, Gobel, Jeff, Gillie, Dan, Condreay, JPatrick

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Diastereomeric atropisomers of the tricyclo[9.3.1.03,8]pentadecane ring system. Synthesis and structural studies von Shea, K. J, Gilman, Jeffrey W, Haffner, Curt D, Dougherty, T. Kirk

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Substituted N-{3-[(1,1-dioxido-1,2-benzothiazol-3-yl)(phenyl)amino]propyl}b enzamide analogs as potent Kv1.3 ion channel blockers. Part 2 von Haffner, Curt D, Thomson, Stephen A, Guo, Yu, Petrov, Kimberly, Larkin, Andrew, Banker, Pierette, Schaaf, Gregory, Dickerson, Scott, Gobel, Jeff, Gillie, Dan, Condreay, JPatrick, Poole, Chuck, Carpenter, Tiffany, Ulrich, John

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An efficient synthesis of 3-pyridyl-N-oxide steroides: Inhibitors of 5α-reductase von Haffner, Curt

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Synthesis of 6-azacholesten-3-ones: Potent inhibitors of 5α-reductase von Haffner, Curt

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