Tracking the clonal origin of lethal prostate cancer von Haffner, Michael C, Mosbruger, Timothy, Esopi, David M, Fedor, Helen, Heaphy, Christopher M, Walker, David A, Adejola, Nkosi, Gürel, Meltem, Hicks, Jessica, Meeker, Alan K, Halushka, Marc K, Simons, Jonathan W, Isaacs, William B, De Marzo, Angelo M, Nelson, William G, Yegnasubramanian, Srinivasan

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Decreased 5-hydroxymethylcytosine is associated with neural progenitor phenotype in normal brain and shorter survival in malignant glioma von Orr, Brent A, Haffner, Michael C, Nelson, William G, Yegnasubramanian, Srinivasan, Eberhart, Charles G

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Targeting advanced prostate cancer with STEAP1 chimeric antigen receptor T cell and tumor-localized IL-12 immunotherapy von Bhatia, Vipul, Kamat, Nikhil V., Pariva, Tiffany E., Wu, Li-Ting, Tsao, Annabelle, Sasaki, Koichi, Sun, Huiyun, Javier, Gerardo, Nutt, Sam, Coleman, Ilsa, Hitchcock, Lauren, Zhang, Ailin, Rudoy, Dmytro, Gulati, Roman, Patel, Radhika A., Roudier, Martine P., True, Lawrence D., Srivastava, Shivani, Morrissey, Colm M., Haffner, Michael C., Nelson, Peter S., Priceman, Saul J., Ishihara, Jun, Lee, John K.

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Asporin Restricts Mesenchymal Stromal Cell Differentiation, Alters the Tumor Microenvironment, and Drives Metastatic Progression von Hughes, Robert M, Simons, Brian W, Khan, Hamda, Miller, Rebecca, Kugler, Valentina, Torquato, Samantha, Theodros, Debebe, Haffner, Michael C, Lotan, Tamara, Huang, Jessie, Davicioni, Elai, An, Steven S, Riddle, Ryan C, Thorek, Daniel L J, Garraway, Isla P, Fertig, Elana J, Isaacs, John T, Brennen, W Nathaniel, Park, Ben H, Hurley, Paula J

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Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers von Haffner, Michael C, Chaux, Alcides, Meeker, Alan K, Esopi, David M, Gerber, Jonathan, Pellakuru, Laxmi G, Toubaji, Antoun, Argani, Pedram, Iacobuzio-Donahue, Christine, Nelson, William G, Netto, George J, De Marzo, Angelo M, Yegnasubramanian, Srinivasan

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SND1 binds to ERG and promotes tumor growth in genetic mouse models of prostate cancer von Liao, Sheng-You, Rudoy, Dmytro, Frank, Sander B., Phan, Luan T., Klezovitch, Olga, Kwan, Julian, Coleman, Ilsa, Haffner, Michael C., Li, Dapei, Nelson, Peter S., Emili, Andrew, Vasioukhin, Valeri

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Reciprocal YAP1 loss and INSM1 expression in neuroendocrine prostate cancer von Asrani, Kaushal, Torres, Alba FC, Woo, Juhyung, Vidotto, Thiago, Tsai, Harrison K, Luo, Jun, Corey, Eva, Hanratty, Brian, Coleman, Ilsa, Yegnasubramanian, Srinivasan, De Marzo, Angelo M, Nelson, Peter S, Haffner, Michael C, Lotan, Tamara L

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An in Situ Atlas of Mitochondrial DNA in Mammalian Tissues Reveals High Content in Stem and Proliferative Compartments von Chen, Jiayu, Zheng, Qizhi, Peiffer, Lauren B., Hicks, Jessica L., Haffner, Michael C., Rosenberg, Avi Z., Levi, Moshe, Wang, Xiaoxin X., Ozbek, Busra, Baena-Del Valle, Javier, Yegnasubramanian, Srinivasan, De Marzo, Angelo M.

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DNA hypomethylation arises later in prostate cancer progression than CpG island hypermethylation and contributes to metastatic tumor heterogeneity von Yegnasubramanian, Srinivasan, Haffner, Michael C, Zhang, Yonggang, Gurel, Bora, Cornish, Toby C, Wu, Zhijin, Irizarry, Rafael A, Morgan, James, Hicks, Jessica, DeWeese, Theodore L, Isaacs, William B, Bova, G Steven, De Marzo, Angelo M, Nelson, William G

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Convergent network effects along the axis of gene expression during prostate cancer progression von Charmpi, Konstantina, Guo, Tiannan, Zhong, Qing, Wagner, Ulrich, Sun, Rui, Toussaint, Nora C, Fritz, Christine E, Yuan, Chunhui, Chen, Hao, Rupp, Niels J, Christiansen, Ailsa, Rutishauser, Dorothea, Rüschoff, Jan H, Fankhauser, Christian, Saba, Karim, Poyet, Cedric, Hermanns, Thomas, Oehl, Kathrin, Moore, Ariane L, Beisel, Christian, Calzone, Laurence, Martignetti, Loredana, Zhang, Qiushi, Zhu, Yi, Martínez, María Rodríguez, Manica, Matteo, Haffner, Michael C, Aebersold, Ruedi, Wild, Peter J, Beyer, Andreas

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Disulfiram is a DNA demethylating agent and inhibits prostate cancer cell growth von Lin, Jianqing, Haffner, Michael C., Zhang, Yonggang, Lee, Byron H., Brennen, W. Nathaniel, Britton, Justin, Kachhap, Sushant K., Shim, Joong Sup, Liu, Jun O., Nelson, William G., Yegnasubramanian, Srinivasan, Carducci, Michael A.

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Genomic analysis identifies frequent deletions of Dystrophin in olfactory neuroblastoma von Gallia, Gary L., Zhang, Ming, Ning, Yi, Haffner, Michael C., Batista, Denise, Binder, Zev A., Bishop, Justin A., Hann, Christine L., Hruban, Ralph H., Ishii, Masaru, Klein, Alison P., Reh, Douglas D., Rooper, Lisa M., Salmasi, Vafi, Tamargo, Rafael J., Wang, Qing, Williamson, Tara, Zhao, Tianna, Zou, Ying, Meeker, Alan K., Agrawal, Nishant, Vogelstein, Bert, Kinzler, Kenneth W., Papadopoulos, Nickolas, Bettegowda, Chetan

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Genome-wide comparison of the transcriptomes of highly enriched normal and chronic myeloid leukemia stem and progenitor cell populations von Gerber, Jonathan M, Gucwa, Jessica L, Esopi, David, Gurel, Meltem, Haffner, Michael C, Vala, Milada, Nelson, William G, Jones, Richard J, Yegnasubramanian, Srinivasan

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MYC is a regulator of androgen receptor inhibition-induced metabolic requirements in prostate cancer von Crowell, Preston D., Giafaglione, Jenna M., Jones, Anthony E., Nunley, Nicholas M., Hashimoto, Takao, Delcourt, Amelie M.L., Petcherski, Anton, Agrawal, Raag, Bernard, Matthew J., Diaz, Johnny A., Heering, Kylie Y., Huang, Rong Rong, Low, Jin-Yih, Matulionis, Nedas, Navone, Nora M., Ye, Huihui, Zoubeidi, Amina, Christofk, Heather R., Rettig, Matthew B., Reiter, Robert E., Haffner, Michael C., Boutros, Paul C., Shirihai, Orian S., Divakaruni, Ajit S., Goldstein, Andrew S.

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Prostate-specific membrane antigen expression in the neovasculature of gastric and colorectal cancers von Haffner, Michael C., MD, Kronberger, Irmgard E., MD, Ross, Jeffrey S., MD, Sheehan, Christine E., MD, Zitt, Matthias, MD, Mühlmann, Gilbert, MD, Öfner, Dietmar, MD, Zelger, Bettina, MD, Ensinger, Christian, MD, Yang, Ximing J., MD, PhD, Geley, Stephan, MD, Margreiter, Raimund, MD, Bander, Neil H., MD

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Global 5-Hydroxymethylcytosine Levels Are Profoundly Reduced in Multiple Genitourinary Malignancies von Munari, Enrico, Chaux, Alcides, Vaghasia, Ajay M, Taheri, Diana, Karram, Sarah, Bezerra, Stephania M, Gonzalez Roibon, Nilda, Nelson, William G, Yegnasubramanian, Srinivasan, Netto, George J, Haffner, Michael C

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AIM1 is an actin-binding protein that suppresses cell migration and micrometastatic dissemination von Haffner, Michael C., Esopi, David M., Chaux, Alcides, Gürel, Meltem, Ghosh, Susmita, Vaghasia, Ajay M., Tsai, Harrison, Kim, Kunhwa, Castagna, Nicole, Lam, Hong, Hicks, Jessica, Wyhs, Nicolas, Biswal Shinohara, Debika, Hurley, Paula J., Simons, Brian W., Schaeffer, Edward M., Lotan, Tamara L., Isaacs, William B., Netto, George J., De Marzo, Angelo M., Nelson, William G., An, Steven S., Yegnasubramanian, Srinivasan

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Chromosome-wide mapping of DNA methylation patterns in normal and malignant prostate cells reveals pervasive methylation of gene-associated and conserved intergenic sequences von Yegnasubramanian, Srinivasan, Wu, Zhijin, Haffner, Michael C, Esopi, David, Aryee, Martin J, Badrinath, Raghav, He, Tony L, Morgan, James D, Carvalho, Benilton, Zheng, Qizhi, De Marzo, Angelo M, Irizarry, Rafael A, Nelson, William G

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Epigenetic and transcriptional analysis reveals a core transcriptional program conserved in clonal prostate cancer metastases von Severson, Tesa M., Zhu, Yanyun, De Marzo, Angelo M., Jones, Tracy, Simons, Jonathan W., Nelson, William G., Yegnasubramanian, Srinivasan, Freedman, Matthew L., Wessels, Lodewyk, Bergman, Andries M., Haffner, Michael C., Zwart, Wilbert

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Reversible epigenetic alterations mediate PSMA expression heterogeneity in advanced metastatic prostate cancer von Sayar, Erolcan, Patel, Radhika A, Coleman, Ilsa M, Roudier, Martine P, Zhang, Ailin, Mustafi, Pallabi, Low, Jin-Yih, Hanratty, Brian, Ang, Lisa S, Bhatia, Vipul, Adil, Mohamed, Bakbak, Hasim, Quigley, David A, Schweizer, Michael T, Hawley, Jessica E, Kollath, Lori, True, Lawrence D, Feng, Felix Y, Bander, Neil H, Corey, Eva, Lee, John K, Morrissey, Colm, Gulati, Roman, Nelson, Peter S, Haffner, Michael C

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