Recent Advances in Prostate Cancer Treatment and Drug Discovery von Nevedomskaya, Ekaterina, Baumgart, Simon J, Haendler, Bernard

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From Omics to Multi-Omics Approaches for In-Depth Analysis of the Molecular Mechanisms of Prostate Cancer von Nevedomskaya, Ekaterina, Haendler, Bernard

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Targeting DNA Damage Response in Prostate and Breast Cancer von Wengner, Antje M., Scholz, Arne, Haendler, Bernard

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Transcriptional addiction in cancer cells is mediated by YAP/TAZ through BRD4 von Zanconato, Francesca, Battilana, Giusy, Forcato, Mattia, Filippi, Letizia, Azzolin, Luca, Manfrin, Andrea, Quaranta, Erika, Di Biagio, Daniele, Sigismondo, Gianluca, Guzzardo, Vincenza, Lejeune, Pascale, Haendler, Bernard, Krijgsveld, Jeroen, Fassan, Matteo, Bicciato, Silvio, Cordenonsi, Michelangelo, Piccolo, Stefano

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Addressing the Reciprocal Crosstalk between the AR and the PI3K/AKT/mTOR Signaling Pathways for Prostate Cancer Treatment von Raith, Fabio, O'Donovan, Daniel H, Lemos, Clara, Politz, Oliver, Haendler, Bernard

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Preclinical Anticipation of On- and Off-Target Resistance Mechanisms to Anti-Cancer Drugs: A Systematic Review von Dziubańska-Kusibab, Paulina J, Nevedomskaya, Ekaterina, Haendler, Bernard

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Exploiting Epigenetic Alterations in Prostate Cancer von Baumgart, Simon J, Haendler, Bernard

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Dysregulated Transcriptional Control in Prostate Cancer von Baumgart, Simon J, Nevedomskaya, Ekaterina, Haendler, Bernard

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Discovery of a Chemical Tool Inhibitor Targeting the Bromodomains of TRIM24 and BRPF von Bennett, James, Fedorov, Oleg, Tallant, Cynthia, Monteiro, Octovia, Meier, Julia, Gamble, Vicky, Savitsky, Pavel, Nunez-Alonso, Graciela A, Haendler, Bernard, Rogers, Catherine, Brennan, Paul E, Müller, Susanne, Knapp, Stefan

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Darolutamide antagonizes androgen signaling by blocking enhancer and super‐enhancer activation von Baumgart, Simon J., Nevedomskaya, Ekaterina, Lesche, Ralf, Newman, Richard, Mumberg, Dominik, Haendler, Bernard

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Inhibition of BET bromodomain-dependent XIAP and FLIP expression sensitizes KRAS-mutated NSCLC to pro-apoptotic agents von Klingbeil, Olaf, Lesche, Ralf, Gelato, Kathy A, Haendler, Bernard, Lejeune, Pascale

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Preclinical evaluation of the BET bromodomain inhibitor BAY 1238097 for the treatment of lymphoma von Bernasconi, Elena, Gaudio, Eugenio, Lejeune, Pascale, Tarantelli, Chiara, Cascione, Luciano, Kwee, Ivo, Spriano, Filippo, Rinaldi, Andrea, Mensah, Afua A., Chung, Elaine, Stathis, Anastasios, Siegel, Stephan, Schmees, Norbert, Ocker, Matthias, Zucca, Emanuele, Haendler, Bernard, Bertoni, Francesco

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Enhanced Antitumor Efficacy of Radium-223 and Enzalutamide in the Intratibial LNCaP Prostate Cancer Model von Suominen, Mari I, Knuuttila, Matias, Schatz, Christoph A, Schlicker, Andreas, Vääräniemi, Jukka, Sjöholm, Birgitta, Alhoniemi, Esa, Haendler, Bernard, Mumberg, Dominik, Käkönen, Sanna-Maria, Scholz, Arne

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The fate of the duplicated androgen receptor in fishes: a late neofunctionalization event? von Douard, Véronique, Brunet, Frédéric, Boussau, Bastien, Ahrens-Fath, Isabelle, Vlaeminck-Guillem, Virginie, Haendler, Bernard, Laudet, Vincent, Guiguen, Yann

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Dual targeting of the androgen receptor and PI3K/AKT/mTOR pathways in prostate cancer models improves antitumor efficacy and promotes cell apoptosis von Sugawara, Tatsuo, Nevedomskaya, Ekaterina, Heller, Simon, Böhme, Annika, Lesche, Ralf, Ahsen, Oliver, Grünewald, Sylvia, Nguyen, Holly M., Corey, Eva, Baumgart, Simon J., Georgi, Victoria, Pütter, Vera, Fernández‐Montalván, Amaury, Vasta, James D., Robers, Matthew B., Politz, Oliver, Mumberg, Dominik, Haendler, Bernard

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The potent AMPK inhibitor BAY-3827 shows strong efficacy in androgen-dependent prostate cancer models von Lemos, Clara, Schulze, Volker K., Baumgart, Simon J., Nevedomskaya, Ekaterina, Heinrich, Tobias, Lefranc, Julien, Bader, Benjamin, Christ, Clara D., Briem, Hans, Kuhnke, Lara P., Holton, Simon J., Bömer, Ulf, Lienau, Philip, von Nussbaum, Franz, Nising, Carl F., Bauser, Marcus, Hägebarth, Andrea, Mumberg, Dominik, Haendler, Bernard

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Recent developments in antiandrogens and selective androgen receptor modulators von Haendler, Bernard, Cleve, Arwed

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The ubiquitin-specific protease USP10 modulates androgen receptor function von Faus, Hortensia, Meyer, Hellmuth-Alexander, Huber, Martina, Bahr, Inke, Haendler, Bernard

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BAY 1024767 blocks androgen receptor mutants found in castration-resistant prostate cancer patients von Sugawara, Tatsuo, Lejeune, Pascale, Köhr, Silke, Neuhaus, Roland, Faus, Hortensia, Gelato, Kathy A, Busemann, Matthias, Cleve, Arwed, Lücking, Ulrich, von Nussbaum, Franz, Brands, Michael, Mumberg, Dominik, Jung, Klaus, Stephan, Carsten, Haendler, Bernard

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Darolutamide is a potent androgen receptor antagonist with strong efficacy in prostate cancer models von Sugawara, Tatsuo, Baumgart, Simon J., Nevedomskaya, Ekaterina, Reichert, Kristin, Steuber, Holger, Lejeune, Pascale, Mumberg, Dominik, Haendler, Bernard

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