Synthesis and Biological Evaluation of 2- and 3-Aminobenzo[b]thiophene Derivatives as Antimitotic Agents and Inhibitors of Tubulin Polymerization von Romagnoli, Romeo, Baraldi, Pier Giovanni, Carrion, Maria Dora, Cara, Carlota Lopez, Preti, Delia, Fruttarolo, Francesca, Pavani, Maria Giovanna, Tabrizi, Mojgan Aghazadeh, Tolomeo, Manlio, Grimaudo, Stefania, Di Cristina, Antonella, Balzarini, Jan, Hadfield, John A, Brancale, Andrea, Hamel, Ernest

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Novel Syntheses of Cis and Trans Isomers of Combretastatin A-4 von Gaukroger, Keira, Hadfield, John A, Hepworth, Lucy A, Lawrence, Nicholas J, McGown, Alan T

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The total synthesis of an aurone isolated from Uvaria hamiltonii: Aurones and flavones as anticancer agents von LAWRENCE, Nicholas J, RENNISON, David, MCGOWN, Alan T, HADFIELD, John A

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A 2-step synthesis of Combretastatin A-4 and derivatives as potent tubulin assembly inhibitors von Barnes, Natalie G., Parker, Anthony W., Ahmed Mal Ullah, Amjed A., Ragazzon, Patricia A., Hadfield, John A.

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Anticancer phototherapy using activation of E-combretastatins by two-photon-induced isomerization von Scherer, Kathrin M, Bisby, Roger H, Botchway, Stanley W, Hadfield, John A, Parker, Anthony W

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Tubulin-binding dibenz[c,e]oxepines: Part 2. Structural variation and biological evaluation as tumour vasculature disrupting agents von Rossington, Steven B, Hadfield, John A, Shnyder, Steven D, Wallace, Timothy W, Williams, Kaye J

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Tubulin as a target for anticancer drugs: Agents which interact with the mitotic spindle von Jordan, Allan, Hadfield, John A., Lawrence, Nicholas J., McGown, Alan T.

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Three-dimensional imaging and uptake of the anticancer drug combretastatin in cell spheroids and photoisomerization in gels with multiphoton excitation von Scherer, Kathrin M, Bisby, Roger H, Botchway, Stanley W, Hadfield, John A, Haycock, John W, Parker, Anthony W

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Novel cyanocombretastatins as potent tubulin polymerisation inhibitors von Jalily, Pouria H., Hadfield, John A., Hirst, Nicholas, Rossington, Steven B.

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Fluorescence lifetime imaging of E- combretastatin uptake and distribution in live mammalian cells von Bisby, Roger H, Botchway, Stanley W, Hadfield, John A, McGown, Alan T, Parker, Anthony W, Scherer, Kathrin M

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Tubulin-binding dibenz[c,e]oxepines as colchinol analogues for targeting tumour vasculature von Edwards, David J, Hadfield, John A, Wallace, Timothy W, Ducki, Sylvie

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Structural requirements for the interaction of combretastatins with tubulin: how important is the trimethoxy unit? von Gaukroger, Keira, Hadfield, John A, Lawrence, Nicholas J, Nolan, Steven, McGown, Alan T

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Potent antimitotic and cell growth inhibitory properties of substituted chalcones von Ducki, Sylvie, Forrest, Richard, Hadfield, John A., Kendall, Alex, Lawrence, Nicholas J., McGown, Alan T., Rennison, David

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Time-resolved nanosecond fluorescence lifetime imaging and picosecond infrared spectroscopy of combretastatin A-4 in solution and in cellular systems von Bisby, Roger H, Botchway, Stanley W, Greetham, Greg M, Hadfield, John A, McGown, Alan T, Parker, Anthony W, Scherer, Kathrin M, Towrie, Mike

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Positron emission tomography of murine liver metastases and the effects of treatment by combretastatin A-4 von Zhao, Sha, Moore, James V., Waller, Michael L., McGown, Alan T., Hadfield, John A., Pettit, George R, Hastings, David L.

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Cytotoxic michael-type amine adducts of α-methylene lactones alantolactone and isoalantolactone von LAWRENCE, Nicholas J, MCGOWN, Alan T, NDUKA, Jane, HADFIELD, John A, PRITCHARD, Robin G

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Synthesis and evaluation of double bond substituted combretastatins von Hadfield, John A., Gaukroger, Keira, Hirst, Nicholas, Weston, Anna P., Lawrence, Nicholas J., McGown, Alan T.

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A High-Yielding Synthesis of the Naturally Occurring Antitumour Agent Irisquinone von Hadfield, John A, McGown, Alan T, Butler, John

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A practical radiosynthesis of a tritium-labelled fluorocombretastatin von Hadfield, John A., Hirst, Nicholas, Gaukroger, Keira, Lawrence, Nicholas J., McGown, Alan T.

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Synthesis of cytotoxic furonaphthoquinones: Regiospecific synthesis of diodantunezone and 2-ethylfuronaphthoquinones von Perry, Philip J, Pavlidis, Vasilios H, Hadfield, John A

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