Thienothiopyran-2-sulfonamides: a novel class of water-soluble carbonic anhydrase inhibitors von Ponticello, Gerald S, Freedman, Mark B, Habecker, Charles N, Lyle, Paulette A, Schwam, Harvey, Varga, Sandor L, Christy, Marcia E, Randall, William C, Baldwin, John J

Volltext

Identification and SAR for a selective, nonpeptidyl thrombin inhibitor von Naylor-Olsen, Adel M., Ponticello, Gerald S., Lewis, S.Dale, Mulichak, Anne M., Chen, Zhonguo, Habecker, Charles N., Phillips, Brian T., Sanders, William M., Tucker, Thomas J., Shafer, Jules A., Vacca, Joseph P.

Volltext

Positions of His‐64 and a bound water in human carbonic anhydrase II upon binding three structurally related inhibitors von Smith, Graham M., Alexander, Richard S, Christianson, David W., Mckeever, Brian M., Ponticello, Gerald S., Springer, James P., Randall, William C., Baldwin, John J., Habecker, Charles N.

Volltext

Topically active carbonic anhydrase inhibitors. 2. Benzo[b]thiophenesulfonamide derivatives with ocular hypotensive activity von Graham, Samuel L, Shepard, Kenneth L, Anderson, Paul S, Baldwin, John J, Best, Darryl B, Christy, Marcia E, Freedman, Mark B, Gautheron, Pierre, Habecker, Charles N

Volltext

A deuterium isotope effect on the inhibition of gastric secretion by N,N-dimethyl-N'-[2-(diisopropylamino)ethyl]-N'-(4,6-dimethyl-2-pyridyl)urea. Synthesis of metabolites von Hoffman, Jacob M, Habecker, Charles N, Pietruszkiewicz, Adolph M, Bolhofer, William A, Cragoe, Edward J, Torchiana, Mary Lou, Hirschmann, Ralph

Volltext

Utilization of .alpha.,.beta.-unsaturated acids as Michael acceptors for the synthesis of thieno[2,3-b]thiopyrans von Ponticello, Gerald S, Freedman, Mark B, Habecker, Charles N, Holloway, M. Katharine, Amato, Joseph S, Conn, Robin S, Baldwin, John J

Volltext

An unusual dimer of 2-mercaptothiophene von Ponticello, Gerald S, Habecker, Charles N, Varga, Sandor L, Pitzenberger, Steven M

Volltext

Beta 1-selective adrenoceptor antagonists: examples of the 2-[4-[3-(substituted amino)-2-hydroxypropoxy]phenyl]imidazole class. 2 von Baldwin, J J, Christy, M E, Denny, G H, Habecker, C N, Freedman, M B, Lyle, P A, Ponticello, G S, Varga, S L, Gross, D M, Sweet, C S

Volltext

Conformational requirements for histamine H2-receptor inhibitors: a structure-activity study of phenylene analogs related to cimetidine and tiotidine von Hoffman, Jacob M, Pietruszkiewicz, Adolph M, Habecker, Charles N, Phillips, Brian T, Bolhofer, William A, Cragoe, Edward J, Torchiana, Mary Lou, Lumma, William C, Baldwin, John J

Volltext

Inhibition of gastric acid secretion by 1,8-naphthyridin-2(1H)-ones von Bolhofer, William A, Hoffman, Jacob M, Habecker, Charles N, Pietruszkiewicz, Adolph M, Cragoe, Edward J, Torchiana, Mary Lou

Volltext

2-Mercaptoacetamidines as gastric antisecretory agents von Bolhofer, William A, Habecker, Charles N, Pietruszkiewicz, Adolph M, Torchiana, Mary Lou, Jacoby, Henry I, Stone, Clement A

Volltext

4-Oxospiro[benzopyran-2,4'-piperidines] as class III antiarrhythmic agents. Pharmacological studies on 3,4-dihydro-1'-[2-(benzofurazan-5-yl)ethyl]-6-methanesulfonamidospiro[(2H)-1-... von Elliott, Jason M, Selnick, Harold G, Claremon, David A, Baldwin, John J, Buhrow, Susan A, Butcher, John W, Habecker, Charles N, King, Stella W, Lynch, Joseph J

Volltext

Maleamic Acids That Affect Plasma Cholesterol and Penicillin Excretion von Schultz, Everett M, Bolhofer, William A, Augenblick, Albert, Bicking, John B, Habecker, Charles N, Horner, J. Kenneth, Kwong, Sara F, Pietruszkiewicz, Adolph M

Volltext

4-Oxospiro[benzopyran-2,4'-piperidines] as class III antiarrhythmic agents. Pharmacological studies on 3,4-dihydro-1'-[2-(benzofurazan-5-yl)- ethyl]-6-methanesulfonamidospiro[(2H)-... von Elliott, J M, Selnick, H G, Claremon, D A, Baldwin, J J, Buhrow, S A, Butcher, J W, Habecker, C N, King, S W, Lynch, Jr, J J, Phillips, B T

Volltext

Inhibitors of gastric acid secretion: 3,4-diamino-1,2,5-thiadiazole 1-oxides and 1,1-dioxides as urea equivalents in a series of histamine H2 receptor antagonists von Lumma, William C, Anderson, Paul S, Baldwin, John J, Bolhofer, William A, Britcher, Susan F, Clineschmidt, Bradley V, Denny, George H, Habecker, Charles N, Hirshfield, Jordan M

Volltext

Topically active carbonic anhydrase inhibitors. 2. Benzo(b)thiophene sulfonamide derivatives with ocular hypotensive activity von Graham, S L, Shepard, K L, Anderson, P S, Baldwin, J J, Best, D B, Christy, ME, Freedman, M B, Gautheron, P, Habecker, C N

Volltext

Inhibitors of gastric acid secretion: antisecretory 2-pyridylurea derivatives von Bolhofer, William A, Deana, Albert A, Habecker, Charles N, Hoffman, Jacob M, Gould, Norman P, Pietruszkiewicz, Adolph M, Prugh, John D, Torchiana, Mary Lou, Cragoe, Edward J, Hirschmann, Ralph

Volltext

Topically active carbonic anhydrase inhibitors. II: Benzo[b]thiophenesulfonamide derivatives with ocular hypotensive activity von GRAHAM, S. L, SHEPARD, K. L, LYLE, P. A, MICHELSON, S. R, PONTICELLO, G. S, ROBB, C. M, SCHWAM, H, SMITH, A. M, SMITH, R. L, SONDEY, J. M, STROHMAIER, K. M, SUGRUE, M. F, ANDERSON, P. S, VARGA, S. L, BALDWIN, J. J, BEST, D. B, CHRISTY, M. E, FREEDMAN, M. B, GAUTHERON, P, HABECKER, C. N, HOFFMAN, J. M

Volltext

β1-Selective adrenoceptor antagonists: examples of the 2-[4-[3-(substituted amino)-2-hydroxypropoxy]phenyl]imidazole class. 2 von BALDWIN, J. J, CHRISTY, M. E, DENNY, G. H, HABECKER, C. N, FREEDMAN, M. B, LYLE, P. A, PONTICELLO, G. S, VARGA, S. L, GROSS, D. M, SWEET, C. S

Volltext

Conformational requirements for histamine H sub(2)-receptor inhibitors: A structure-activity study of phenylene analogues related to cimetidine and tiotidine von Hoffman, J M, Pietruszkiewicz, AM, Habecker, C N, Phillips, B T, Bolhofer, WA, Cragoe, EJ Jr, Torchiana, M L, Lumma, WC Jr, Baldwin, J J

Volltext