Cereblon is a direct protein target for immunomodulatory and antiproliferative activities of lenalidomide and pomalidomide von Lopez-Girona, A, Mendy, D, Ito, T, Miller, K, Gandhi, A K, Kang, J, Karasawa, S, Carmel, G, Jackson, P, Abbasian, M, Mahmoudi, A, Cathers, B, Rychak, E, Gaidarova, S, Chen, R, Schafer, P H, Handa, H, Daniel, T O, Evans, J F, Chopra, R

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Apremilast, a cAMP phosphodiesterase‐4 inhibitor, demonstrates anti‐inflammatory activity in vitro and in a model of psoriasis von Schafer, PH, Parton, A, Gandhi, AK, Capone, L, Adams, M, Wu, L, Bartlett, JB, Loveland, MA, Gilhar, A, Cheung, Y‐F, Baillie, GS, Houslay, MD, Man, H‐W, Muller, GW, Stirling, DI

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Inhibition of the Nrf2 transcription factor by the alkaloid trigonelline renders pancreatic cancer cells more susceptible to apoptosis through decreased proteasomal gene expression... von Arlt, A, Sebens, S, Krebs, S, Geismann, C, Grossmann, M, Kruse, M-L, Schreiber, S, Schäfer, H

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Isolation or Replenishment? The Case of Partner Network Exclusivity and Partner Loss in Later Life von Sun, Haosen, Schafer, Markus H

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Phase 2 Trial of Iberdomide in Systemic Lupus Erythematosus von Merrill, Joan T, Werth, Victoria P, Furie, Richard, van Vollenhoven, Ronald, Dörner, Thomas, Petronijevic, Milan, Velasco, Jorge, Majdan, Maria, Irazoque-Palazuelos, Fedra, Weiswasser, Michael, Korish, Shimon, Ye, Ying, Gaudy, Allison, Schafer, Peter H, Liu, Zhaohui, Agafonova, Nataliya, Delev, Nikolay

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Neurochemical Monitoring of Traumatic Brain Injury by the Combined Analysis of Plasma Beta-Synuclein, NfL, and GFAP in Polytraumatized Patients von Halbgebauer, Rebecca, Halbgebauer, Steffen, Oeckl, Patrick, Steinacker, Petra, Weihe, Eberhard, Schafer, Martin K.-H., Roselli, Francesco, Gebhard, Florian, Huber-Lang, Markus, Otto, Markus

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Discussion networks, physician visits, and non-conventional medicine: Probing the relational correlates of health care utilization von Schafer, Markus H.

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Apremilast is a selective PDE4 inhibitor with regulatory effects on innate immunity von Schafer, P.H., Parton, A., Capone, L., Cedzik, D., Brady, H., Evans, J.F., Man, H.-W., Muller, G.W., Stirling, D.I., Chopra, R.

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Phosphodiesterase 4 in inflammatory diseases: Effects of apremilast in psoriatic blood and in dermal myofibroblasts through the PDE4/CD271 complex von Schafer, Peter H., Truzzi, Francesca, Parton, Anastasia, Wu, Lei, Kosek, Jolanta, Zhang, Ling-Hua, Horan, Gerald, Saltari, Annalisa, Quadri, Marika, Lotti, Roberta, Marconi, Alessandra, Pincelli, Carlo

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CC-122, a pleiotropic pathway modifier, mimics an interferon response and has antitumor activity in DLBCL von Hagner, Patrick R., Man, Hon-Wah, Fontanillo, Celia, Wang, Maria, Couto, Suzana, Breider, Mike, Bjorklund, Chad, Havens, Courtney G., Lu, Gang, Rychak, Emily, Raymon, Heather, Narla, Rama Krishna, Barnes, Leo, Khambatta, Gody, Chiu, Hsiling, Kosek, Jolanta, Kang, Jian, Amantangelo, Michael D., Waldman, Michelle, Lopez-Girona, Antonia, Cai, Ti, Pourdehnad, Michael, Trotter, Matthew, Daniel, Thomas O., Schafer, Peter H., Klippel, Anke, Thakurta, Anjan, Chopra, Rajesh, Gandhi, Anita K.

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The Pharmacodynamic Impact of Apremilast, an Oral Phosphodiesterase 4 Inhibitor, on Circulating Levels of Inflammatory Biomarkers in Patients with Psoriatic Arthritis: Substudy Res... von Wang, Andrew, Fang, Lorraine, Chen, Peng, Schafer, Peter H., Chopra, Rajesh

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On the locality of asymmetric close relations: spatial proximity and health differences in a senior community von Schafer, Markus H

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Aiolos Overexpression in Systemic Lupus Erythematosus B Cell Subtypes and BAFF-Induced Memory B Cell Differentiation Are Reduced by CC-220 Modulation of Cereblon Activity von Nakayama, Yumi, Kosek, Jolanta, Capone, Lori, Hur, Eun Mi, Schafer, Peter H, Ringheim, Garth E

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Childhood Misfortune as a Threat to Successful Aging: Avoiding Disease von Schafer, Markus H., Ferraro, Kenneth F.

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Increased proteasome subunit protein expression and proteasome activity in colon cancer relate to an enhanced activation of nuclear factor E2-related factor 2 (Nrf2) von Arlt, A, Bauer, I, Schafmayer, C, Tepel, J, Müerköster, S Sebens, Brosch, M, Röder, C, Kalthoff, H, Hampe, J, Moyer, M P, Fölsch, U R, Schäfer, H

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Health and Network Centrality in a Continuing Care Retirement Community von Schafer, Markus H.

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Childhood (Mis)fortune, Educational Attainment, and Adult Health: Contingent Benefits of a College Degree? von Schafer, Markus H., Wilkinson, Lindsay R., Ferraro, Kenneth F.

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Lenalidomide downregulates the cell survival factor, interferon regulatory factor‐4, providing a potential mechanistic link for predicting response von Lopez‐Girona, Antonia, Heintel, Daniel, Zhang, Ling‐Hua, Mendy, Derek, Gaidarova, Svetlana, Brady, Helen, Bartlett, Justin Blake, Schafer, Peter H., Schreder, Martin, Bolomsky, Arnold, Hilgarth, Bernadette, Zojer, Niklas, Gisslinger, Heinz, Ludwig, Heinz, Daniel, Tom, Jäger, Ulrich, Chopra, Rajesh

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Measuring cereblon as a biomarker of response or resistance to lenalidomide and pomalidomide requires use of standardized reagents and understanding of gene complexity von Gandhi, Anita K., Mendy, Derek, Waldman, Michelle, Chen, Gengxin, Rychak, Emily, Miller, Karen, Gaidarova, Svetlana, Ren, Yan, Wang, Maria, Breider, Michael, Carmel, Gilles, Mahmoudi, Afshin, Jackson, Pilgrim, Abbasian, Mahan, Cathers, Brian E., Schafer, Peter H., Daniel, Tom O., Lopez‐Girona, Antonia, Thakurta, Anjan, Chopra, Rajesh

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Age Identity, Gender, and Perceptions of Decline: Does Feeling Older Lead to Pessimistic Dispositions About Cognitive Aging? von Schafer, Markus H., Shippee, Tetyana P.

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